Clinical trials: Treatment as usual
Myocardial Infarction
Left Atrial Distensibility and Left Ventricular Filling Pressure in Acute Myocardial Infarction
Left atrial volume (LAV) provides the significant prognostic information in the general population and patients with heart disease, including acute myocardial infarction, left ventricular dysfunction, mitral regurgitation…
- Trial name
- NCT01168609
- Testing
- Primary percutaneous coronary intervention
- Where
- Taiwan
- Volunteers
- 521 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Somatic Symptom Disorder
App-Based Self-Management for Somatic Symptom Disorder and MUS: A Pilot Study
Objectives The primary objective of this study is to evaluate the effectiveness of an eight-week self-management mobile application for adults experiencing somatic symptom disorder (SSD) or medically unexplained symptoms (MUS).
- Trial name
- NCT07296406
- Testing
- Arm I (App Intervention), Arm II (Waitlist Control)
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Gangnam Severance Hospital
Older Adults
STAND UP - Sedentary Behaviour in Older Adults: Investigating a New Therapeutic Paradigm
Research has shown that reducing the time spent sitting can reduce the risk of many diseases, such as diabetes and heart disease, and improve health.
- Trial name
- STAND-UP (NCT02453204)
- Testing
- Sitting, Standing, Walking
- Where
- 2 sites in United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Substance-Related Disorders
Behavioral Treatment for Substance Abuse
This pilot project will evaluate a new mind-body intervention called Mind-Body Bridging (MBB) for reducing substance abuse problems in women who are undergoing a substance abuse treatment program.
- Trial name
- NCT01438346
- Testing
- Substance Abuse Education, Mind-body Bridging
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Utah
Non-Insertional Achilles Tendinopathy
Dry Needling and Exercise for Mid-portion Achilles Tendinopathy
The purpose of this study is to determine if adding ultrasound-guided tendon dry needling with mechanical needle stimulation to a standard heavy, slow resistance (HSR) exercise program improves outcomes for individuals with…
- Trial name
- NCT07642583
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Brooke Army Medical Center
Arthritis, Rheumatoid, Arthritis, Psoriatic
WORKWELL: Testing Work Advice for People With Arthritis
Background: Inflammatory arthritis (IA) causes work disability, absenteeism (sick leave) and presenteeism (reduced productivity) at high cost to individuals, employers and society.
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Arthritis, Inflammatory
- Trial name
- WORKWELL (NCT03942783)
- Testing
- WORKWELL, Control
- Where
- 18 sites in United Kingdom
- Volunteers
- 249 people
- Sponsor
- University of Salford
Self-Injurious Behavior
Zero Self-Harm - a Mobile Phone Application to Reduce Non-suicidal Self-injury
Non-suicidal self-injury (NSSI), the deliberate, self-inflicted destruction of body tissue without suicidal intent and for purposes not socially sanctioned, is an increasing health care problem in Denmark.
- Trial name
- NCT04463654
- Testing
- Zero Self-Harm app
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Prevent Disorders in Children Adopted From Foster Care
Adoption-specific Treatment Prevention Pilot Trial
This study seeks to pilot a manualized adoption-specific intervention aimed at providing a preventive intervention for families adopting children ages 5-14 years where family reunification has been terminated and the family is…
- Trial name
- ADAPT (NCT01744951)
- Testing
- ADAPT
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pain, Postoperative, Tonsillar Bleeding
Dexamethasone and Postoperative Bleeding Following Tonsillectomy in Children
Tonsillectomy is one of the most frequently performed surgical interventions in children. However, it is associated with a high incidence of PostOperative Nausea and Vomiting (PONV), severe pain and haemorrhage.
- Conditions
- Pain, Postoperative, Tonsillar Bleeding, Postoperative Nausea and Vomiting
- Trial name
- Blueberry (NCT04188431)
- Testing
- Dexamethasone, Sodium chloride
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 523 people
- Sponsor
- Walid HABRE
Arterial Hypertension
Temperature-elevating Armbaths for Arterial Hypertension
The goal of this randomized controlled trial is to learn about the effect of a hydrotherapeutic approach - a temperature-elevating armbath - in people with arterial hypertention.
- Trial name
- NCT05928702
- Testing
- temperature-elevating armbath
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Kliniken Essen-Mitte
Stress Disorders, Post-Traumatic
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life.
- Trial name
- ANG-P (NCT02560805)
- Testing
- Microneurography, Combat virtual reality video clip, Handgrip Exercise
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Behavior Problems, Oppositional Defiant Disorder
The Effectiveness of Parent-Child Interaction Therapy (PCIT)
The purpose of this study was to investigate whether a type of parent-based intervention, Parent-Child Interaction Therapy will lower symptoms of behavior problems in young children more than treatment as usual.
- Conditions
- Behavior Problems, Oppositional Defiant Disorder, Conduct Disorder
- Trial name
- NCT01085305
- Testing
- Parent-Child Interaction Therapy, TAU
- Where
- 2 sites in Norway
- Volunteers
- 63 people
- Sponsor
- Norwegian University of Science and Technology
Depression, Anxiety, Palliative Care
Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care
This study is a randomized clinical trial of a problem-solving therapy intervention for family caregivers of individuals with cancer receiving outpatient palliative care.
- Conditions
- Depression, Anxiety, Palliative Care, Caregivers, Cancer
- Trial name
- NCT04867122
- Testing
- Problem-Solving Therapy, Attention-matched Control, In-depth interviews
- Where
- 3 sites in United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Heart Failure
Effectiveness of a Multidisciplinary Care Management Program for High-risk Patients With Heart Failure (PROMIC)
OBJECTIVE: To evaluate the effectiveness of a multidisciplinary care management collaborative program for high-risk patients with heart failure (HF) who are admitted at hospital, based on the 6 components of the Chronic Care…
- Trial name
- PROMIC (NCT02436161)
- Testing
- Care management program "PROMIC"
- Volunteers
- 250 people
- Sponsor
- Basque Health Service
Cardiac Rehabilitation
Incentives and Case Management to Improve Cardiac Care: Healthy Lifestyle Program
Participation in outpatient cardiac rehabilitation (CR) decreases morbidity and mortality for patients hospitalized with myocardial infarction, coronary bypass surgery or percutaneous revascularization.
- Trial name
- HeLP (NCT03759873)
- Testing
- Incentives, Case Management
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- University of Vermont
Substance Use Disorder (SUD)
Culturally Adapted Motivational Interviewing With CBT and Mindfulness Based Relapse Prevention for Substance Use Disorder in Pakistan (CAMIAB)
The study has both quantitative and qualitative components. The aim of study is to: 1. Culturally adapt and integrate the existing Motivational Interviewing with Cognitive Behavioral Therapy(MICBT) and Mindfulness based Relapse…
- Trial name
- NCT04885569
- Testing
- Motivational interviewing with CBT (MICBT), Mindfulness based Relapse Prevention (MBRP), CAMIAB
- Where
- Pakistan
- Volunteers
- 260 people
- Sponsor
- Pakistan Institute of Living and Learning
Mental Health Impairment
Effectiveness of Tracking Goals in Counselling
Recent evidence suggests that focusing on positive goals rather than problems to avoid, may be associated with better psychological health and attainment of goals.
- Trial name
- Goals in MIND (NCT03000153)
- Testing
- Completing the Goals Form
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Problem Behavior
Examining Variation in the Impact of School-Wide Positive Behavioral Interventions and Supports (PBIS)
To conduct a randomized controlled trial of School-Wide Positive Behavioral Interventions and Supports, which is a school-based prevention program aimed at reducing behavior problems in children.
- Trial name
- NCT01583127
- Testing
- Positive Behavioral Interventions & Supports
- Where
- United States
- Volunteers
- 32,986 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Asthma
Clinical Effect of Reflexology and Homeopathy Added to Conventional Asthma Management
There is a lack of scientific evidence that homeopathy and reflexology is effective treatment of asthma. Systematic reviews have found that many clinical trials testing homeopathy and reflexology have major flaws, such as small…
- Trial name
- NCT01426061
- Testing
- Reflexology plus conventional treatment, Homeopathy plus conventional treatment, Conventional treatment
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- University of Aarhus
Non-Muscle Invasive Bladder Cancer
A Study Comparing Standard Treatments in People With Non-Muscle Invasive Bladder Cancer (NMIBC)
The purpose of this study is to compare the effectiveness of different FDA-approved/NCCN-recommended drug treatments for NMIBC. In particular, the FDA-approved drug nadofaragene firadenovec will be compared to usual care with…
- Trial name
- NCT06929286
- Testing
- Nadofaragene Firadenovec, Gemcitabine, Docetaxel
- Where
- 9 sites in United States
- Volunteers
- 125 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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