Clinical trials: Treatment as usual
Individual Psychiatric Disorder, Couple Dysfunction
Assessing Psychotherapy Outcome With Feedback
This study is a comparison of client outcomes in two different types of psychotherapy treatment. In one condition clients will receive treatment-as-usual (TAU); the therapy that they would normally receive.
- Conditions
- Individual Psychiatric Disorder, Couple Dysfunction, Family Dysfunction
- Trial name
- NCT02023736
- Testing
- Systemic Therapy Inventory of Change (STIC), Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- The Family Institute at Northwestern University
Histiocytosis
A Study of Memory, Thinking, and Brain Imaging in Adults With Histiocytosis
The purpose of this study is to try to understand how histopcytosis can cause symptoms or problems in the brain. The tests being done in the study will look at memory and thinking as well as brain function via MRI scan.
- Trial name
- NCT03127709
- Testing
- Trail Making Test, Parts A & B, Brief Test of Attention, Symbol Span
- Where
- 4 sites in United States
- Volunteers
- 13 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Psychological Distress
Integrated Mindfulness-Based Cognitive Therapy for Singapore Malay Muslims
Singapore's Institute of Mental Health (IMH) identified the need for culture-based research and clinical intervention catering to the minority populations in Singapore to foster treatment sustainability and recovery.
- Trial name
- IPS-MBCT (NCT05237336)
- Testing
- Mindfulness-based Cognitive Therapy, Counselling as usual
- Where
- 2 sites in Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- International Islamic University Malaysia
Stroke
Effects of Training Caregivers on the Outcomes of Stroke Survivors and Caregivers in Zimbabwe
The burden of stroke has continued to increase in Zimbabwe in the last 3 decades. resulting in increased burden of care to family caregivers.
- Trial name
- NCT02569099
- Testing
- Caregiver training
- Where
- Zimbabwe
- Volunteers
- 376 people
- Sponsor
- University of Zimbabwe
Access to Care, Psychological Distress
ACT Workshops: A Novel Delivery Modality to Increase Access to Care for Rural Veterans
This study investigates access, effectiveness, and acceptability of 1-day ACT workshops on problematic mental health symptoms.
- Trial name
- NCT05196464
- Testing
- Acceptance and Commitment Therapy (ACT) Workshop, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Syracuse VA Medical Center
Pediatric Cancer, Leukemia
Integrative Neuromuscular Training in Adolescents and Children Treated for Cancer
The INTERACT study is a nation-wide, population-based randomized controlled trial to investigate the effects of 6-month integrative neuromuscular training during anti-cancer treatment on lower body muscle strength, metabolic…
- Conditions
- Pediatric Cancer, Leukemia, Neoplasms, Lymphoma
- Trial name
- INTERACT (NCT04706676)
- Testing
- Integrative neuromuscular training (INT), Active control group: home-based training program, motivational counseling session
- Where
- 3 sites in Denmark
- Volunteers
- 132 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Heart Disease
Program Using a Mobile Application Versus Telephone Advice on Patients at Risk of Coronary Heart Disease : a Pilot RCT
Topic: Effectiveness of the nurse-led support programme using a mobile application versus telephone advice on patients at risk of coronary heart disease - a randomized controlled trial Aims: The study aims to compare the effects…
- Trial name
- NCT04054258
- Testing
- App support Programme (ASP) group
- Where
- 2 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Unipolar Depression, Anxiety Disorder
Improve: Integrating Emotion Focused Components Into Psychological Therapy
The primary purpose of this study is to compare the efficacy of two treatment-as-usual (TAU) conditions: TAU with integration of emotion focused components (EFT) and TAU with focus on self-regulation (SR).
- Conditions
- Unipolar Depression, Anxiety Disorder, Adjustment Disorder
- Trial name
- Improve (NCT02822443)
- Testing
- Psychological therapy (PT) as TAU with integrated emotion focused components (TAU - EFT), Psychological therapy (PT) as TAU with focus on self-regulation (TAU - SR)
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- University of Bern
Head and Neck Cancer
Induction Chemotherapy Followed by Cetuximab and Radiation Therapy for Head and Neck Cancer
More than 50% of Head and Neck cancers are locally advanced at presentation. Although surgery, in combination with other modalities like radiation therapy can achieve 40-50% five year survival rates, resection in the head and…
- Trial name
- DREXNECK (NCT01467115)
- Testing
- Radiotherapy, Leucovorin, Cetuximab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Drexel University College of Medicine
Septic Shock
Albumin Replacement Therapy in Septic Shock
Albumin is a key regulator of fluid distribution within the extracellular space and possesses several properties beyond its oncotic activity, including binding and transport of several endogenous molecules, anti-inflammatory and…
- Trial name
- ARISS (NCT03869385)
- Testing
- Albutein® 200 g/L or Plasbumin® 20
- Where
- 27 sites in Germany
- Volunteers
- 440 people
- Sponsor
- Jena University Hospital
Posttraumatic Stress Disorder, Substance Use Disorders
Written Exposure in Substance Treatment
The purpose of this pilot randomized clinical trial is to test the feasibility and efficacy of written exposure therapy (WET) for posttraumatic stress disorder (PTSD) within the context of residential substance use disorder (SUD)…
- Trial name
- WEST (NCT06296940)
- Testing
- Written Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Potomac Health Foundations
Traumatic Brain Injury, Concussion, Brain
Early Team Based Neuro-rehabilitation After Traumatic Brain Injury - a Pilot Study
The aim is to evaluate the study design, procedure and measurements in a randomised controlled pilot study.
- Trial name
- NCT03771950
- Testing
- Early team based neuro-rehabilitation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Vastra Gotaland Region
Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression
Effects of Osteopathic Treatment on Pulmonary Function After Coronary Artery Bypass Graft Surgery
The purpose of this study is to determine the short and long term effects of osteopathic treatment on pulmonary function, pain and quality of life in patients after coronary artery bypass graft (CABG) surgery.
- Conditions
- Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression, Pain, Quality of Life
- Trial name
- OSTinCARE (NCT01714791)
- Testing
- Usual care, Osteopathic treatment
- Where
- Belgium
- Volunteers
- 112 people
- Sponsor
- Hartcentrum Hasselt
Language Impairment, Down Syndrome
Phenotypic Specific Communication Intervention for Children With Down Syndrome
Children with Down syndrome (DS) have greater difficulty acquiring expressive language than is predicted by their general cognitive abilities and language comprehension (Miller, 1999).
- Trial name
- Merck (NCT02158390)
- Testing
- Jasper-EMT with words and AAC
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
ADHD
FOCUS ADHD Mobile Health App for Adult ADHD Patients
The study is a randomized clinical trial to evaluate the efficacy on treatment adherence, performance and usability of the mobile health solution FOCUS ADHD, in combination with a discount application in the purchase of…
- Trial name
- NCT05551689
- Testing
- Psychostimulant, FOCUS ADHD App
- Where
- Brazil
- Volunteers
- 73 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Borderline Personality Disorder
BOSCOT : A Randomised Controlled Trial of Cognitive Behavioural Therapy in Borderline Personality Disorder
The aim of the study was to investigate if the addition of cognitive behavioural therapy to treatment as usual (CBT plus TAU) in participants with borderline personality disorder would decrease the number of participants with…
- Trial name
- BOSCOT (NCT00538135)
- Testing
- Cognitive Behavioural Therapy, Treatment as usual
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- University of Aberdeen
Elderly Infection, Frailty
Antibiotic Dosing in Geriatric Patients At the Emergency Department
In this pilot study, we will investigate whether - with the current dosing regimens, used in the Ghent University Hospital - pharmacodynamic targets regarding beta-lactam antibiotics (more specific Amoxicilline-Clavulanate…
- Conditions
- Elderly Infection, Frailty, Frail Elderly Syndrome, Infection, Bacterial
- Trial name
- AGED (NCT04436991)
- Testing
- Blood sampling, Sputum sample, Hemoculture
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- University Hospital, Ghent
Post-COVID19 Condition
Plasma Exchange Therapy for Post- COVID-19 Condition: A Pilot, Randomized Double-Blind Study
PAX is a prospective, randomized (1:1), double-blind, placebo-controlled study, that have as a objective to evaluate the safety and tolerability of plasma exchange (PE) in patients with Post Acute Covid-19 Syndrome (PCC)…
- Trial name
- NCT05445674
- Testing
- Plasma Exchange Procedure
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Segmental Long Bone Defects
Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects
The United States Department of Defense (DoD) is funding exciting new research at the University of Texas Medical Branch (UTMB) Department of Orthopaedic Surgery and Rehabilitation that can be a major improvement in the treatment…
- Trial name
- NCT02015390
- Testing
- Autogenous RIA bone grafting, Allogeneic bone grafting
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Dementia
Animal-assisted or Robot-assisted Interventions in Health Promotion for Elderly With Dementia
The overall research aim of this study is to investigate changes in measures related to the risk of falls among elderly with dementia participating in animal-assisted or robot-assisted interventions.
- Trial name
- NCT01998490
- Testing
- Animal-assisted activity, Robot-assisted activity
- Where
- 15 sites in Norway
- Volunteers
- 88 people
- Sponsor
- Norwegian University of Life Sciences
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