Clinical trials: Treatment as usual
Emotion Regulation
Neuroplastic Adaptations in Youth at High Risk for Developing Psychopathology
This pilot study aims to inform decision-making for a bigger study we intend to conduct in the future. The larger investigation will explore how helpful a treatment program for youth (ages 17 - 24) with emotion dysregulation (ED)…
- Trial name
- NCT05586425
- Testing
- Emotion Regulation Skills + Treatment as Usual, Treatment as Usual
- Volunteers
- 20 people
- Sponsor
- McMaster University
Metabolic Syndrome, Obesity
Prevention of the Metabolic Syndrome by New Lifestyle Intervention Methods
This intervention aims to reduce obesity by using new type of nutritional and lifestyle therapy and in parallel, tailored persuasive information and communications technology (ICT)-technology based application.
- Conditions
- Metabolic Syndrome, Obesity, Overweight, Cardiovascular Disease
- Trial name
- PrevMetSyn (NCT01959763)
- Testing
- Weight loss counseling program
- Where
- Finland
- Volunteers
- 574 people
- Sponsor
- University of Oulu
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Generalized Anxiety Disorder
Cognitive Behavioral Therapy (CBT) for Latinos With Generalized Anxiety Disorder in the General Medical Sector
The purpose of this project is to implement culturally adapted Cognitive Behavioral Therapy (CBT) based interventions in general health settings that are delivered to reduce Generalized Anxiety Disorder (GAD) symptoms, increase…
- Trial name
- NCT01203293
- Testing
- Cognitive behavior based therapy, Treatment as usual
- Where
- Puerto Rico
- Volunteers
- 90 people
- Sponsor
- University of Puerto Rico
Asthma
Effect of Electronic Monitoring and Feedback on Adherence to Easyhaler Controller Medication in Patients With Asthma
Effect of Electronic Monitoring and Feedback on Adherence to Easyhaler Controller Medication in Patients with Asthma
- Trial name
- eMOFEE (NCT04869384)
- Testing
- Reminders and feedback to improve adherence, No reminders and feedback to improve adherence
- Where
- Germany
- Volunteers
- 158 people
- Sponsor
- Orion Corporation, Orion Pharma
Military Family, Brain Injuries, Traumatic
Effects of PSTon Mental Health Outcomes in Caregivers of Post-9/11 Combat Veterans With a Traumatic Brain Injury
The primary aim of this study is to assess the efficacy of PST for positively impacting distressed military family caregiver's depression and burden levels (secondary outcomes), ultimately enhancing their mental health quality of…
- Trial name
- NCT03211884
- Testing
- Problem-Solving Thearpy
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Cerebral Hemorrhage, Stroke
The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial
Continued uncertainty exists over benefits of early intensive blood pressure (BP) lowering in acute intracerebral hemorrhage (ICH), related to the non-significant primary outcomes, patient selection, and discordant results of…
- Conditions
- Cerebral Hemorrhage, Stroke, Hypertension, Diabetes
- Trial name
- INTERACT3 (NCT03209258)
- Testing
- Care bundle of active management, Usual care
- Where
- China
- Volunteers
- 7,067 people
- Sponsor
- The George Institute for Global Health, China
Severe COPD
Advance Care Planning Individualised Approach and Research Projec
The study will investigate the effect of a palliative approach in the out-patient management of patients with COPD.
- Trial name
- AIR (NCT03915743)
- Testing
- palliative care
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Herlev and Gentofte Hospital
Rheumatoid Arthritis, Patient Involvement
E-learning in Patient Education to Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease that primarily causes pain, swelling and stiffness in the joints. The disease may reduce normal functioning and thereby quality of life.
- Conditions
- Rheumatoid Arthritis, Patient Involvement, Self Efficacy
- Trial name
- WEB-RA (NCT04669340)
- Testing
- E-learning patient education, Standard face-to-face patient education
- Where
- 5 sites in Denmark
- Volunteers
- 181 people
- Sponsor
- Aarhus University Hospital
Developmental Language Disorder
Maximizing Outcomes for Preschoolers With Developmental Language Disorders
The objective of the proposed study is to evaluate the efficacy of the Enhanced Milieu Teaching-Sentence Focus (EMT-SF) intervention, implemented by caregivers and interventionists, relative to a control condition enrolling 108…
- Trial name
- NCT03782493
- Testing
- the Enhanced Milieu Teaching-Sentence Focus
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Multiple Myeloma, Hodgkin Disease
Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma
The purpose of this study is to find out whether acupuncture treatments can reduce the need for opioid medication when managing pain caused by chemotherapy.
- Conditions
- Multiple Myeloma, Hodgkin Disease, Non-Hodgkin Lymphoma
- Trial name
- NCT04459416
- Testing
- Acupuncture, opioid, Assessments
- Where
- 2 sites in United States
- Volunteers
- 299 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Depression
Dance-movement Therapy in the Treatment of Adolescent Depression
The aim of this research is to measure the effectiveness of Dance movement therapy in the treatment of adolescent depression.
- Trial name
- DMT (NCT07293806)
- Testing
- Dance movement therapy
- Where
- 2 sites in Finland
- Volunteers
- 140 people
- Sponsor
- Helsinki University Central Hospital
Periodontitis (Stage 3), Periodontitis Stage IV
Application of a Fasting-mimicking Diet in Obese Patients With Periodontitis Stage III-IV
This study will evaluate whether a fasting-mimicking diet (FMD) can improve the systemic and periodontal response to non-surgical periodontal treatment in obese adults with severe periodontitis.
- Trial name
- NCT07549633
- Testing
- Fast mimicking diet group, Normal diet group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Urinary Tract Infections, Sepsis
Use of Antibiotic Based Irrigation for Ureteroscopic Treatment of Urolithiasis
The purpose of the study is to investigate whether the use of gentamicin-based irrigation fluid during ureteroscopy decreases the risk of UTIs and other post-operative infections after surgery.
- Trial name
- NCT06007352
- Testing
- Gentamicin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Mellitus, Type 2
Telehealth Remote Patient Monitoring Study in People With Type 2 Diabetes
Telehealth remote patient monitoring is a means of using communications technology - such as telephones, computers, and the Internet - to connect patients remotely with their healthcare team from their homes.
- Trial name
- NCT01715649
- Testing
- Patient education, self-monitoring of blood glucose and remote patient monitoring of blood glucose
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Sutter Health
Electroconvulsive Therapy Treated Patients
Neural Biomarkers of Electroconvulsive Therapy Response
In the proposed study, the investigators will utilize resting-state functional MRI (fMRI) and structural MRI-based electrical field modeling to study the effect of electroconvulsive therapy on human neural circuitry.
- Trial name
- NCT04763655
- Testing
- clinical and neuropsychological testing
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwell Health
HIV/AIDS
The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services
The BRIDGES Project seeks to test a program intended to help women living with HIV who face specific barriers due to culture, gender, violence, trauma, adverse mental health, and substance use to be able to better access HIV…
- Trial name
- BRIDGES (NCT04295876)
- Testing
- The BRIDGES Project Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Alcohol Use Disorder, Alcohol Abuse
Internet-delivered Cognitive Behavior Therapy for Problematic Alcohol Use in a Working Life Setting
Internet-based cognitive behavioral treatment (ICBT) for mental health issues has been successfully implemented in routine health care and research indicates that ICBT can also be applied to decrease problematic alcohol use in…
- Trial name
- Simba (NCT06774716)
- Testing
- Internet-based cognitive behavioural treatment and relapse prevention, Face-to-face cognitive behavioural treatment or short-term psycodynamic therapy with relapse prevention
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Stockholm University
Childhood Aggression
Adapting Dialectical Behavior Therapy for Children in Residential Care
I: Conduct Pilot Randomized Clinical Trial of Dialectical Behavior Therapy for children (DBT-C) in residential as compared with Treatment-As-Usual (TAU) (60 children in DBT-C and 60 children in the comparison condition).
- Trial name
- DBT-C (NCT01547052)
- Testing
- DBT for children, Enhanced Supportive-Educational therapy
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Weill Medical College of Cornell University
Hypercholesterolaemia
LATAM LOWERS LDL-C
This is an open label, patient-level 1:1 randomized clinical trial in a multi-country study aiming to evaluate the real-world impact of inclisiran + Usual Care (UC) vs UC alone on LDL-C lowering, patient-reported outcomes, and…
- Trial name
- NCT06501443
- Testing
- Usual care, KJX839
- Where
- 11 sites in Argentina, Brazil
- Volunteers
- 520 people
- Sponsor
- Novartis Pharmaceuticals
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