Clinical trials: Treatment as usual
Surgical Procedures, Operative
Arterial Pulse Waveform Contour Analysis for Intraoperative Goal Directed Therapy in Major Spine Surgery
This study evaluates whether using information from a special arterial blood pressure monitor to guide how much fluid is given during surgery changes how long a patient stays in the hospital after the surgery.
- Trial name
- NCT01124474
- Testing
- goal directed therapy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Loma Linda University
Parent-Child Relationship, Parenting
CARE Mentalizing-Focused Parenting Group Outcomes Study
The primary objective of this clinical trial is to evaluate the 12-week mentalizing-focused group parenting intervention, Connecting and Reflecting Experience (CARE), relative to a treatment as usual (TAU) group in an outpatient…
- Trial name
- NCT04580459
- Testing
- CARE Parenting Group Treatment, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Montefiore Medical Center
Emotional Distress
Experiential Avoidance as the Mechanism of Mindfulness Intervention in Reducing Emotional Distress: Daily Dairy Research
This study hopes to: 1. explore whether three weeks of MIED could promote experiential avoidance. 2. explore experiential avoidance could be a mediation of outcomes of MIED.
- Trial name
- NCT05981248
- Testing
- Mindfulness Intervention for Emotional Distress
- Volunteers
- 200 people
- Sponsor
- Peking University
Gastric Retention
Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery
Glucagon-like peptide-1 agonists (GLP-1RA) are a family of medications used for diabetes and weight loss. One of their effect is to slow down stomach emptying.
- Trial name
- RESIDUAL (NCT06500143)
- Testing
- Gastric ultrasound
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Depression, Couples (Persons)
Social Interaction and Compassion in Depression
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners.
- Trial name
- SIDE (NCT03080025)
- Testing
- CBCT® (Cognitively Based Compassion-Training)
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Behavior, Communication
Thirty Million Words- Well Baby Initiative
The purpose of the proposed study is to determine the efficacy of a multi-media educational curriculum in strengthening the early learning environments of vulnerable children, and positively impacting their language and cognitive…
- Conditions
- Behavior, Communication, Language
- Trial name
- TMW-WB (NCT02812017)
- Testing
- Thirty Million Words- Well Baby, Safety Starts at Home
- Where
- 10 sites in United States
- Volunteers
- 952 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Overweight, Obesity
Mindfulness Intervention for Overweight Primary Care Patients
Mindfulness has been applied in the United States and Europe to improve both physical and psychological health, however, it is still poorly studied in Brazil.
- Trial name
- MindEat (NCT02893150)
- Testing
- TAU, TAU+MBHP, TAU+MB-EAT
- Where
- Brazil
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Centro Mente Aberta de Mindfulness
Painful Diabetic Neuropathy
Multimodal Intervention for Painful Diabetic Neuropathy: NeuOst Feasibility Trial
This is the feasibility study of a single-site parallel three-armed participant-blinded controlled randomised efficacy trial of a 5-week course of the 'NeuOst treatment', compared to a designated control intervention, and to…
- Trial name
- NeuOst (NCT06423391)
- Testing
- NeuOst, Control Intervention, Usual Care
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University College of Osteopathy
Obesity and Overweight, Sleep Disorder
Overweight and Obesity in Adolescents - Sleep Behavioral Intervention
Sleep plays a crucial role in energy balance, alongside diet and physical activity. Research has linked poor sleep quality and short sleep duration to obesity and cardiometabolic risk, such as insulin resistance and hypertension.
- Trial name
- SLEEP-OB (NCT07255274)
- Testing
- Sleep Behavioral Intervention, Standard Obesity Treatment
- Where
- 2 sites in Portugal
- Volunteers
- 126 people
- Sponsor
- University of Beira Interior
Epilepsy, Aging Disorder
ZEBinix® Retention Rate in Epilepsy in Elderly Patients
The incidence of provoked and unprovoked seizures is known to increase with advancing age. Eslicarbazepine acetate (ESL) is one of the third generation of antiepileptic drugs (AEDs) that have been developed in the last ten years…
- Conditions
- Epilepsy, Aging Disorder, Aging, Epilepsy; Seizure
- Trial name
- ZEBRE (NCT04221282)
- Testing
- Zebinix
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Attention Deficit Hyperactivity Disorder
Mindfulness Training for Children With Attention-Deficit/Hyperactivity Disorder (ADHD) and Mindful Parenting
This study evaluates the effectiveness of an 8-week mindfulness group training for children (8-16 years old) with ADHD in combination with a parallel mindful parenting training for their parents.
- Trial name
- MindChamp (NCT03220308)
- Testing
- MYmind mindfulness training, Care-as-usual for children (8-16 years old) with ADHD
- Where
- 3 sites in Netherlands
- Volunteers
- 103 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Alcohol Use Disorder
Enhancing Prospective Thinking in Early Recovery (HOME)
The goal of this clinical trial is to use a novel virtual reality intervention to test for efficacy in reducing alcohol use and increasing abstinence, with concomitant increases in future self-identification, future time…
- Trial name
- HOME (NCT06302413)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Indiana University
Emotional Disorder, Depression
Cost-benefit Evaluation of a Transdiagnostic Psychological Treatment for Emotional Disorders in Primary Care
The aim of this study is to compare, in cost-effectiveness and cost-utility terms, a brief transdiagnostic cognitive-behavioural therapy in two different modes, individual and group, with the treatment usually administered in…
- Conditions
- Emotional Disorder, Depression, Somatoform Disorders, Anxiety Disorders
- Trial name
- PsicAP-Costs (NCT04847310)
- Testing
- Group brief transdiagnostic cognitive-behavioral therapy, Individual brief transdiagnostic cognitive-behavioral therapy, Treatment as usual
- Where
- 3 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Universidad de Córdoba
Myocardial Infarction With Non-Obstructive Coronary Artery, Ischemia With Non-Obstructive Coronary Artery
Intracoronary Provocative Test With Acetylcholine in Patients With INOCA and MINOCA
Coronary vasomotor disorders, occurring both at microvascular and epicardial level, have been demonstrated as responsible for myocardial ischemia in a sizeable group of patients undergoing coronary angiography (CAG), with…
- Trial name
- Provoke (NCT05714319)
- Testing
- Data collection, Clinical follow-up
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Type 1 Diabetes Mellitus, Depressive Symptoms
Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms in Adolescents With Type 1 Diabetes Mellitus
This study evaluates the use of an established internet-based cognitive behavioral therapy intervention in a group of adolescents with type 1 diabetes and mild to moderate depressive symptoms.
- Trial name
- NCT03655067
- Testing
- CATCH-IT
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Texas Southwestern Medical Center
Insomnia, Cancer
Clinical Benefit of Cognitive Behaviour Therapy (CBT) for Insomnia in Cancer Patients
The purpose of this study is to conduct a formal controlled evaluation of the potential benefits of CBT for insomnia in cancer patients.
- Trial name
- NCT00134108
- Testing
- Cognitive Behaviour Therapy
- Where
- United Kingdom
- Sponsor
- NHS Greater Glasgow and Clyde
Attention Deficit Hyperactivity Disorder
Psychoeducational Groups for Adults With ADHD
This pilot study aims to assess patient satisfaction and preliminary efficacy of a psychoeducational group treatment, using a randomized waitlist-controlled trial, at two different outpatient clinics in mid-Norway.
- Trial name
- NCT03337425
- Testing
- Psychoeducational group therapy, Waiting list, Standard treatment
- Where
- 2 sites in Norway
- Volunteers
- 46 people
- Sponsor
- Norwegian University of Science and Technology
Smoking Cessation
Motivating Change in Aging Smokers
The purpose of this research is to evaluate messages that motivate older smokers to make quit attempts using evidence based smoking treatments (EBSTs).
- Trial name
- NCT05194917
- Testing
- Older Smoker Motivational Intervention, Control Motivational Message
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hyperglycemia, Cardiovascular Diseases
REsearching Coronary REduction by Appropriately Targeting Euglycemia (RECREATE Pilot Study)
Insulin will safely reduce glucose levels in patients with acute ST-elevation myocardial infarction and admission hyperglycemia.
- Conditions
- Hyperglycemia, Cardiovascular Diseases, Myocardial Infarction
- Trial name
- RECREATE Pilot (NCT00640991)
- Testing
- glulisine insulin, glargine insulin
- Where
- 13 sites in Argentina, Canada and 1 more
- Volunteers
- 500 people
- Sponsor
- Population Health Research Institute
Obesity, Pregnancy Related
Optimizing Health From Pregnancy Through One Year Postpartum
This study will evaluate the impact of different combinations of intervention as a function of gestational weight gain in pregnant woman. Participants will be randomized at two points during the study.
- Trial name
- HABIT (NCT03069690)
- Testing
- HABITpreg, HABITpost
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- University of Pittsburgh
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