Clinical trials: Vitamin C
NPMc+ AML
Oral Arsenic Trioxide for NPM1-mutated AML
A prospective open-label phase 2 study will be designed to assess the efficacy of oral arsenic trioxide plus azacitidine in preventing relapses in patients with NPM1-mutant AML.
- Trial name
- NCT04689815
- Testing
- Oral Arsenic Trioxide Formulation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Chronic Rhinosinusitis, Intraoperative Bleeding
Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing Sinusoscopy
Functional endoscopic sinus surgery (FESS), or sinusoscopy, is a standard surgical procedure used to treat chronic rhinosinusitis and other conditions of the nasal sinuses.
- Conditions
- Chronic Rhinosinusitis, Intraoperative Bleeding, Blood Loss, Surgical
- Trial name
- NCT07866274
- Testing
- Ascorbic acid
- Volunteers
- 78 people
- Sponsor
- Assiut University
Minimal Erythema Dose
The Effect of 8-week Dietary Intake of Novel Food Supplement on Minimal Erythema Dose
This is a double-blind, randomized, placebo-controlled interventional study of the effect of multiple-dose dietary intake on minimal erythema dose and other skin parameters.
- Trial name
- VIST-TO-UV (NCT06343610)
- Testing
- Active product
- Where
- Slovenia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Burn
Burn Micronutrient Repletion Pilot Study
Burn injury patients undergo a series of metabolic changes that, if untreated, could lead to reduced health outcomes. Nutrition is thought to play a vital role in post-burn recovery.
- Trial name
- NCT00879723
- Testing
- Vitamin and Mineral supplementation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Southern Illinois University
Physical Activity
Training Intervention in a Controlled Population of Frail Elderly
Exercise has a beneficial role in geriatric patients categorized as frail. Nevertheless, it is not known physical training pattern more beneficial for these patients.
- Trial name
- EMTIFE (NCT02331459)
- Testing
- Multicomponent training intervention, Nutritional intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital de la Ribera
Pregnancy
Maternal Vitamin D for Infant Growth (MDIG) Trial
The primary aims of this study are: 1) to determine whether maternal prenatal vitamin D3 supplementation (4200 IU/week, 16,800 IU/week, or 28,000 IU/week) versus placebo increases or decreases infant length at 1 year of age, and…
- Trial name
- MDIG (NCT01924013)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Bangladesh
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Sarcopenia
Effects of L-ARGinine and Liposomal Vitamin C Supplementation On Physical Performance
In older age, reduced mobility is associated with an increased risk of reduced quality of life, disability, institutionalisation, and death, as well as increased healthcare expenditures.
- Trial name
- ARGO (NCT06865261)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
HIV Infections
The Safety and Effectiveness of Different Doses of Vitamin C in HIV-Infected Patients
This is a study to evaluate the tolerance and antiviral effect of oral vitamin C in HIV-infected.
- Trial name
- NCT00001070
- Testing
- Oral Vitamin C
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Alcoholics
Alcohol Abuse or Alcohol Withdrawal: Risk of Latent Scurvy
Scurvy, or latent scurvy, may be underestimated in developed countries, but continue to be described, often as case report. Little is known about the prevalence of vitamin C deficiency in a specific population as withdrawal…
- Trial name
- NCT03467022
- Testing
- Vitamin C
- Volunteers
- 47 people
- Sponsor
- SCP Battistelli
Dup15q Syndrome, Autism Spectrum Disorder
Investigating the Therapeutic Efficacy of All-trans Retinoic Acid in Autism Spectrum Disorder Patients With 15q11-13 Duplication Syndrome
Autism spectrum disorder (ASD) , hereafter referred to as autism, is a group of neurodevelopmental disorders caused by genetic and environmental factors.
- Conditions
- Dup15q Syndrome, Autism Spectrum Disorder, Therapy, All-trans Retinoic Acid
- Trial name
- NCT07079696
- Testing
- ATRA
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Septic Shock, Sepsis
Triple Therapy in Septic Shock Patients
this study is conducted to evaluate the role of the novel triple therapy combination in reducing the mortality rate, reducing the shock time, and reversal of organ damage.
- Conditions
- Septic Shock, Sepsis, Organ Dysfunction Syndrome Sepsis
- Trial name
- NCT04508946
- Testing
- vitamin c - thiamine- hydrocortisone
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Air Force Specialized Hospital, Cairo, Egypt
Critical Limb Ischemia, Peripheral Arterial Disease
Revascularization of Stenosed Vessels Using Optimized Treatment of Rejuveinix for Reversing Endothelial Dysfunction
A Phase I/IIa Dose-Escalation Study Evaluating the Safety, Tolerability and Efficacy of Rejuveinix in Combination With Standard Interventional Therapy for Critical Limb Ischemia Patients with Rutherford Class 4, 5 and 6 Disease
- Trial name
- RESTORE (NCT03041259)
- Testing
- Rejuveinix Low Dose, Rejuveinix High Dose
- Volunteers
- 320 people
- Sponsor
- Reven Pharmaceuticals, Inc.
Xerostomia, Dryness of Mouth
Testing of a Candy in Five Different Versions for the Additional Humidification of the Oral Cavity
This study is to investigate whether a candy can increase moisture of the oral cavity and reduce dryness of mouth.
- Trial name
- DESERTO (NCT04554342)
- Testing
- V01 candy, V02 candy, V03 candy
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Restless Leg Syndrome
Restless Legs Syndrome in Hemodialysis Patients
Restless legs syndrome (RLS) is defined as the spontaneous movement of the limbs (mainly legs) associated with unpleasant - painful sensation which is relieved by moving the affected limb.
- Trial name
- NCT03337529
- Testing
- Vitamin C
- Where
- Lebanon
- Volunteers
- 19 people
- Sponsor
- Makassed General Hospital
Neuroblastoma
ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma
The goal of this clinical research study is to find the highest safe dose of the drug ZactimaTM (ZD6474) in patients with neuroblastoma or medulloblastoma that has gotten worse, has come back, or has not responded to the…
- Trial name
- NCT00533169
- Testing
- ZD6474, Retinoic Acid
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Iron-deficiency Anemia (IDA), Hemoglobin
Comparison of Ferrous Salt vs. Liposomal Iron in Adult Women With Iron-Deficiency Anemia
The goal of this study is to compare ferrous salt and liposomal iron for the treatment of iron-deficiency anemia in adult women. The study will also evaluate how well each treatment is tolerated.
- Conditions
- Iron-deficiency Anemia (IDA), Hemoglobin, Iron Deficiencies, Adverse Effect
- Trial name
- IDA (NCT07556731)
- Testing
- Oral ferrous fumarate administered every 24 hours, Ferrous fumarate administered orally every 48 hours., Liposomal iron formulation.
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Hospital General de Mexico
Anemia, Peritoneal Dialysis
Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis
People with kidney failure are at risk for the development of anemia. Anemia is a decrease in the production of hemoglobin, a substance that carries oxygen in the blood.
- Trial name
- NCT00920413
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Unity Health Toronto
Infertility, Female, Infertility, Male
Effects of Antioxidant Supplementation of Culture Media on IVF Embryos
The goal of this clinical trial is to investigate the impact of repeated antioxidant supplementation on blastocyst utilization and expansion rates in embryos under different oxygen concentrations.
- Trial name
- NCT05919186
- Testing
- EmbryORP®, O2 tension 20%, O2 tension 5%
- Where
- Mexico
- Volunteers
- 293 people
- Sponsor
- Liliana Berenice Ramírez Domínguez
Fusion of Spine (Disease)
The Effectiveness of Vitamin C in Postoperative Pain Management of Single-level Posterior Lumbar Interbody Fusion (PLIF)
Postoperative pain management remains a major challenge for surgeons. Despite huge technological advances in pain management, many researchers have documented that unrelieved pain remains common after surgeries, which is…
- Trial name
- NCT02127060
- Testing
- Vitamin C
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Colon Cleansing for Colonoscopy
Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy
Adequate bowel cleansing is essential for effective colonoscopy. Acceptance of colon preparation affects the quality of colon cleansing.
- Trial name
- NCT01603654
- Testing
- sodium picosulphate magnesium citrate, low-volume PEG -ascorbic acid
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- ASST Fatebenefratelli Sacco
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