Clinical trials: Vitamin D3, active
Bone Density, Bone Health
VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)
Vitamin D supplements are widely promoted for bone health. Both vitamin D and vitamin K are important for deposition of calcium in bone, but little is known about the relationship of vitamin K status and bone health.
- Conditions
- Bone Density, Bone Health, Fractures
- Trial name
- NCT04573946
- Testing
- Omega-3 fatty acids (fish oil), Vitamin D3
- Where
- United States
- Volunteers
- 25,871 people
- Sponsor
- Brigham and Women's Hospital
Fall, Fall Injury Prevention
From Screening to Safety: Implementing the AL-STEADI Initiative in Assisted Living Communities
The goal of this trial is to test the real-world efficacy of AL-STEADI, a fall prevention program, in participating assisted living centers.
- Conditions
- Fall, Fall Injury Prevention, Fall Prevention
- Trial name
- AL-STEADI (NCT07531641)
- Testing
- AL-STEADI, Usual Care Group
- Volunteers
- 700 people
- Sponsor
- Brown University
Corrosive Injury
Evaluation of the Role of N Acetyl Cysteine and Vitamin D in Improving Outcomes After Corrosive Ingestion
The goal of this clinical trial is to learn if N acetyl cysteine and vitaminD work to improve outcomes after corrosive ingestion in children.
- Trial name
- NCT07229456
- Testing
- N Acetyl Cysteine, Vitamin D (Cholecalciferol ), control group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Foot Injuries and Disorders, Ankle Injuries and Disorders
Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients
This clinical trial aims to determine the effects of a 6-day low-dose methylprednisolone course on pain, nausea, and total opioid consumption in patients undergoing foot and ankle surgeries.
- Conditions
- Foot Injuries and Disorders, Ankle Injuries and Disorders, Achilles Tendon Injury
- Trial name
- NCT06780202
- Testing
- medrol dosepak, HYDROcodone Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Emory University
Idiopathic Sudden Sensorineural Hearing Loss
Mechanism and Application of Vitamin D in Idiopathic Sudden Sensorineural Hearing Loss
Clinical Trial Protocol: Investigating the Therapeutic Efficacy of Vitamin D in ISSNHL。Core Research Questions Can vitamin D supplementation improve the prognosis of Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL)? What…
- Trial name
- N (NCT07045883)
- Testing
- Vitamin D Supplementation+ standard treatment, standard treatment
- Where
- China
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University
Anovulatory Infertility
Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome
Poly cystic Ovarian Syndrome (PCOS) is an endocrine disorder of reproductive age defined by "the presence of any two out of three criteria: oligo and/or anovulation, excess androgen activity and/or polycystic ovarian morphology…
- Trial name
- NCT06045351
- Testing
- Vitamin D, Active Comparator
- Where
- Pakistan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Osteoporosis Secondary, Breast Cancer Females
Vitamin k, D-chiro Inositol and α-lactalbumin in Bone Homeostasis
In women with breast cancer undergoing adjuvant hormone therapy, the marked tissue hypoestrogenism induced by therapy with aromatase inhibitors and/or tamoxifen ± GnRH analogues causes a significant acceleration in bone mass…
- Trial name
- Synostea (NCT07256769)
- Testing
- Group 1: calcium carbonate/cholecalciferol, Group 2: Synostea® (calcium carbonate/cholecalciferol/vitamin K/α-lactalbumin/ d-chiro-inositol)
- Where
- 2 sites in Italy
- Volunteers
- 134 people
- Sponsor
- Regina Elena Cancer Institute
Extrapulmonary Tuberculosis
A Multicentric Cohort and Biomarker Study for Improved Care of Patients with Extrapulmonary Tuberculosis
This is a prospective, multicenter, observational study (mEX-TB study) of patients with extrapulmonary tuberculosis (EPTB). Adult patients newly diagnosed with EPTB will prospectively be enrolled into the study.
- Trial name
- mEX-TB (NCT06875336)
- Testing
- biomarker analysis
- Where
- 6 sites in Germany
- Volunteers
- 150 people
- Sponsor
- University of Cologne
Ageing
ICOPE INTENSE-K Pilot Study
ICOPE could constitute the reference model of care for healthy aging. More specifically, our hypothesis is that the intervention implemented in ICOPE may directly or indirectly prevent immuno-senescence, the loss of mobility and…
- Trial name
- NCT07048860
- Testing
- ICOPE intense intervention, Ketone Ester (KE) supplementation, Vitamin D3
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Cardiovascular Risk Factors, Insulin Resistance
Pilot Validation of the STELA Preventive Medicine Platform to Reduce Modifiable Health Risk Factors in Adults (CPM-STELA)
This study evaluates a comprehensive digital health platform called STELA, developed at the Center for Preventive Medicine (CPM) of AGEL Hospital Trinec-Podlesi in Czechia.
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Obesity, Dyslipidemias
- Trial name
- CPM-STELA (NCT07551960)
- Testing
- STELA Digital Preventive Medicine Platform, Comprehensive Preventive Health Assessment
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Metabolic Disease, Mental Health Wellness 1
Healthy Early Life Moments in Singapore
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health…
- Conditions
- Metabolic Disease, Mental Health Wellness 1, Lifestyle Risk Reduction, Maternal Obesity
- Trial name
- HELMS (NCT05207059)
- Testing
- HELMS Lifestyle Intervention
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Birth Weight
Healthy Mums, Healthy Babies: Multiple Micronutrient Supplementation in Ethiopia
Background: This programme effectiveness study responds to the need for evidence on the effect on birthweight of switching from iron-folic acid supplementation (IFA) to multiple micronutrient supplementation (MMS) as part of…
- Trial name
- NCT05708183
- Testing
- Multiple micronutrient supplementation (MMS), Iron folate supplementation (IFA)
- Where
- 6 sites in Ethiopia
- Volunteers
- 25,620 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Allergic Rhinitis, Allergic Rhinitis (AR)
Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis
The goal of this clinical trial is to learn if taking probiotics, vitamin D, or both together can help lower symptoms of allergic rhinitis (AR) and improve quality of life in adults.
- Trial name
- NCT07115342
- Testing
- Standard Allergic Rhinitis Treatment, Combined Vitamin D and Probiotics Supplementation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Oropharynx Cancer, Larynx Cancer
Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck Carcinoma
The aim of this study is to investigate the effect of ATRA (Vesanoid) and the effect of tailored radiotherapy in patients with squamous cell carcinoma of the oropharynx, larynx or hypopharynx.
- Conditions
- Oropharynx Cancer, Larynx Cancer, Hypopharynx Cancer, Primary Head and Neck Tumor
- Trial name
- LYSARI (NCT06706401)
- Testing
- Vesanoid, Standard radiotherapy, Tailored radiotherapy
- Where
- 8 sites in France
- Volunteers
- 460 people
- Sponsor
- Centre Leon Berard
Kidney Diseases, Dialysis; Complications
PRevEnting FracturEs in REnal Disease - 1
PREFERRED-1 is a pilot study designed to determine the feasibility of a large randomized, pragmatic, open-label, comparative-effectiveness trial of denosumab for the prevention of fragility fractures in people receiving…
- Conditions
- Kidney Diseases, Dialysis; Complications, Fragility Fracture, Chronic Kidney Disease-Mineral and Bone Disorder
- Trial name
- PREFERRED-1 (NCT05096195)
- Testing
- Denosumab 60 mg/ml, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate
- Where
- 6 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Inflammatory Bowel Diseases
Association Between Vitamin D Deficiency and Inflammatory Bowel Disease
Crohn's disease (CD) and ulcerative colitis (UC) are two major types of inflammatory bowel disease (IBD) that are identified by different clinical, endoscopic, pathological, and radiologic diagnostic methods.
- Trial name
- NCT07259603
- Testing
- Serum 25(OH)D (Vitamin D3), C- reactive protein, Erthrocyte sedimentation rate
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetes (DM), Vitamin D Deficiency
Comparison of Different Doses of Vitamin D Supplementation on Glycated Haemoglobin and Blood Glucose Parameters With Type II Diabetes Mellitus Having Vitamin d Deficiency
COMPARISON OF DIFFERENT DOSES OF VITAMIN D SUPPLEMENTATION ON GLYCATED HEMOGLOBIN (HbA1c) and BLOOD GLUCOSE PARAMETRS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS HAVING VITAMIN D DEFICIENCY"
- Trial name
- NCT07321223
- Testing
- Vitamin D
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- University of Lahore
Postnatal Women, Vitamin D
Pilates vs Aerobic Exercises on Vitamin D and Ionized Calcium in Postnatal
Vitamin D and calcium levels are negatively affected during postpartum period, making postnatal woman more vulnerable to health issues and consequently lowering her quality of life.
- Trial name
- NCT07566715
- Testing
- Exercise
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Adly A Adam
Autism or Autistic Traits
Clinical Cohort Study of DHA in Neurodevelopmental Disorders
Neurodevelopmental disorders are a group of developmental disorders, including autism spectrum disorders (ASDs), attention deficit hyperactivity disorder (ADHD) and others, that begin at a developmental stage and severely affect…
- Trial name
- NCT05841927
- Testing
- Docosahexaenoic acid supplement
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Fudan University