Clinical trials: Water, completed
Healthy Subjects
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2027 in Healthy Subjects
The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of multiple ascending oral doses of E2027 in healthy participants.
- Trial name
- NCT02873156
- Testing
- E2027
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Gut Microbiome
Effects of a Novel Food Product Containing Microbiota Accessible Carbohydrates on the Human Microbiome
This is a randomized, 2-period crossover study aimed at assessing the effect of taking a food supplement containing a blend of microbial accessible carbohydrates on the diversity of the gut microbiome.
- Trial name
- NCT03058575
- Testing
- Dietary MACs, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study
The overall objective of the proposed study is to determine if Dexmedetomidine HCl (BXCL501) is safe for treatment of alcohol use disorder (AUD) with comorbid posttraumatic stress disorder (PTSD) and also shows potential signals…
- Trial name
- NCT04827056
- Testing
- Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg, Ethanol Infusion
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Type2 Diabetes
Using Nanotechnology Structured Water to Control Blood Glucose in Type 2 Diabetic Patients.
Type 2 DM is due to insulin resistance or low insulin secretion or sometimes a combination of both. Nanotechnology structured water is a type of water that is produced using energy field modulators to change the biological…
- Trial name
- NCT04082351
- Testing
- Nanotechnology structured water ( Magnalife), ordinary water
- Volunteers
- 387 people
- Sponsor
- ALI KAMAL M. SAMI
Skin Diseases, Infectious
Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management
The purpose of this study is to determine if antibiotics are required in the management of skin abscess following incision and drainage.
- Trial name
- NCT00679302
- Testing
- Trimethoprim-sulfamethoxazole
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- St. Louis University
Irritable Bowel Syndrome
Fructose and Fructans in Irritabla Bowel Syndrome
The purpose of the study is to investigate if patients with Irritable Bowel Syndrome (IBS) who also report bloating are more likely to report clinically important gastrointestinal symptoms after consuming fructose or fructans…
- Trial name
- FABS (NCT01776853)
- Testing
- Glucose, Fructose, Fructans
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cerebrovascular Accident
Comparative Efficacy Research of Robot-Assisted Therapy With and Without Constraint-Induced Therapy in Stroke Rehabilitation
There are 3 specific study purposes. First, we will examine the treatment effects of RT combined with dCIT (RT + dCIT) compared to RT, dCIT, and a dose-matched control therapy (DMCT) in stroke patients.
- Trial name
- NCT01907139
- Testing
- Robot-assisted therapy, Distributed constraint-induced therapy, Dose-matched control therapy
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Healthy
Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction
This study will investigate whether growth hormone is modulated by the enzyme SIRT1 and by that is stimulating lipolysis on expense of IGF-I production.
- Trial name
- NCT01209429
- Testing
- GH hormone infusion, 42 hour fast, 12 hour fast
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hydration Status
Hydration Status and Cognitive Performance in Adolescents
Objective: to evaluate hydration status and his impact on cognitive performance in adolescents-based cohort study. Methods: A randomized controlled pilot study is active in ten classes of one middle school (n=214 adolescents aged…
- Trial name
- SMARTH2O (NCT03483831)
- Testing
- Intervention group
- Where
- Italy
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Gastric Varices
Angiography for Evaluation of the Feeder Vessel in EUS-guided Coils and Cyanoacrylate Therapy for Gastric Varices
INTRODUCTION: Bleeding from gastric varices (GV) is associated with a high mortality rate. Injection of cyanoacrylate (CYA) using standard gastroscope has demonstrated to achieve higher hemostasis and lower rebleeding rates…
- Trial name
- NCT03277937
- Testing
- angiography in EUS-injection of coils + CYA
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Cirrhosis
Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis
The methacetin breath test (MBT) is a non-invasive liver function test which measures the ability of the liver to metabolize a tracer dose of a compound to carbon dioxide, which is exhaled.
- Trial name
- NCT01157845
- Testing
- BreathID (Methacetin breath test)
- Where
- 4 sites in United States, Israel
- Volunteers
- 165 people
- Sponsor
- Virginia Commonwealth University
Crohn Disease
Anorectal Function in Perianal Crohn's Disease
Perianal Crohn's disease is a disabling disease associated with increased morbidity and impaired quality of life. It is associated with pain, discharge, fecal incontinence and sexual and psychological impairment.
- Trial name
- NCT03819257
- Testing
- Endoanal ultrasound, High-resolution anorectal manometry, Balloon expulsion test
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Cardiac Ischemia
Ringer Acetate Based Modified Del Nido Cardioplegia Solution Versus HTK Solution Cardioplegia Solution in Cardiac Surgery
Low chloride solutions were proved to be better in resuscitation of emergency cases and decrease the resulting hyperchloremic metabolic acidosis in the last decade.
- Trial name
- HTK (NCT06414330)
- Testing
- Ringer acetate based Del Nido cardioplegia, HTK
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Assiut University
Dehydration
Dehydration, Rehydration, and Blood Viscosity
The purpose of this study is to examine and compare the rehydration effect of Essentia Water, an electrolyzed high-pH bottled water, with industry-standard bottled water purified by reverse osmosis with minerals added, on (1)…
- Trial name
- NCT02118883
- Testing
- Essentia Water, Bottled water
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essentia Water, LLC
Hyperglycemia
Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health
The study aims to assess whether a nutritional drink taken before conception and continuing through pregnancy, assists in the maintenance of healthy glucose metabolism in the mother and promotes offspring health.
- Trial name
- NiPPeR (NCT02509988)
- Testing
- Study nutritional drink, Standard nutritional drink
- Where
- 3 sites in New Zealand, Singapore and 1 more
- Volunteers
- 1,729 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Ovarian Cancer
Vargatef in Addition to First Line Chemotherapy With Interval Debulking Surgery in Patients With Ovarian Cancer
Patients with extensive and bulky disease are often those whose initial surgery is delayed after 3 or 4 cycles of neo-adjuvant chemotherapy.
- Trial name
- CHIVA (NCT01583322)
- Testing
- vargatef
- Where
- 36 sites in France
- Volunteers
- 188 people
- Sponsor
- ARCAGY/ GINECO GROUP
Anesthesia
Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
During major surgical procedures, intravascular volume is maintained with the administration of isotonic fluids such as Lactated Ringers (LR), Normal Saline (NS) or Normosol-R.
- Trial name
- NCT03054922
- Testing
- Normal Saline, Lactated Ringer, Normosol-R Inj
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Nationwide Children's Hospital
Hyperglycemia, Postprandial
Effect of Baobab Fruit on Postprandial Glycaemia in Healthy Adults
Baobab fruits have been traditionally used in Africa due to its therapeutic proprieties attributed to it high polyphenol content.
- Trial name
- NCT05140629
- Testing
- Baobab fruit aqueous extract
- Where
- Portugal
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
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