Clinical trials: Water, completed
Graves Disease, Hyperthyroidism
Impact of SSKI Pre-Treatment on Blood Loss in Thyroidectomy for Graves Disease
The purpose of this study is to determine whether a brief course of SSKI (saturated solution of potassium iodide) administered preoperatively provides any benefit in the surgical management of patients undergoing thyroidectomy as…
- Trial name
- NCT00946296
- Testing
- Potassium Iodide
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Massachusetts, Worcester
Diabetes Mellitus, Type 2
Clinical Study to Assess the Safety and Pharmacokinetics of SRT2104 in Type 2 Diabetic Human Subjects
The primary purpose of this study is to determine the safety and tolerability of SRT2104 (0.25, 0.5, 1.0, and 2.0 g/day) in type 2 diabetic subjects when administered once daily for 28 consecutive days, and to characterize the…
- Trial name
- NCT00937326
- Testing
- SRT2104
- Where
- 61 sites in Bulgaria, Estonia and 6 more
- Volunteers
- 227 people
- Sponsor
- Sirtris, a GSK Company
Dental Caries
Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal
The evolution of conservative dentistry that adopts the preservation of tooth structure and affected dentin that can remineralize and save the pulp from exposure, in addition to pain and fear that companies' traditional caries…
- Trial name
- NCT05733923
- Testing
- Traditional Escavation, Excavation with Sodium Hypochlorite Gel 2.5%., Excavation with Papacarie Duo
- Where
- Syria
- Volunteers
- 90 people
- Sponsor
- Damascus University
Pregnancy
Effects of Antenatal Pelvic Floor Preparation Techniques for Childbirth
Perineal trauma during childbirth is an important etiological factor of various undesirable complications to women's health, with emphasis on pelvic floor dysfunction.
- Trial name
- EAPFPTC (NCT02582580)
- Testing
- Perineal massage, Vaginal Dilator, Pelvic floor muscles training
- Where
- Brazil
- Volunteers
- 63 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Venous Insufficiency
Assessment of the Effect of Spa Therapy on the Quality of Life of Patients with Chronic Venous Insufficiency (NEYRAC)
Evaluation of the effectiveness of a phlebology-oriented spa therapy at 6 months on the quality of life of patients suffering from chronic venous insufficiency of the lower limbs
- Trial name
- NEYRAC (NCT05449743)
- Testing
- Spa therapy
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Le Syndicat Intercommunal pour le Thermalisme et l'Environnement
Influenza
A Randomised, Double-blind, Placebo-controlled Phase IIb Trial to Test FLU-v Vaccine
FLU-v is a vaccine that aims to protect against a wide range of flu viruses. The purpose of this study is to measure the immune responses induced by FLU-v vaccine.
- Trial name
- NCT02962908
- Testing
- FLU-v, adjuvanted FLU-v, Saline
- Where
- Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- PepTcell Limited
Metabolic Syndrome
Dose-response Effect of Whey Protein Consumed as Pre-meal on Postprandial Lipaemia in Subjects With Metabolic Syndrome
Cardiovascular disease (CVD) is one of the most important and frequent causes of death. Postprandial lipidemia (PPL) is an independent risk factor for CVD, besides the traditional risk factors e.g.
- Trial name
- NCT02087124
- Testing
- Whey protein
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital
Obstructive Sleep Apnea-hypopnea Syndrome (OSAHS)
Study of the Effect of an Elastic Compression Medical Device, on Water Balance Change in Healthy Subjects
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by the occurrence of abnormally frequent episodes of interrupted ventilation (apnea) or significant reduction of ventilation (hypopnea) during sleep.
- Trial name
- NCT04911725
- Testing
- Elastic Compression Prototype
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Laboratoires Innothera
Thermogenesis by Different-dosage Mustard Flour Footbaths
Dose-response Relationship of Mustard Flour Footbaths in Healthy Volunteers
A study to explore whether different dosages of mustard flour in footbaths cause different effects on warmth development as well as on general well-being and the autonomic nervous system.
- Trial name
- NCT04321720
- Testing
- 3-g mustard footbath, 6-g mustard footbath, 12-g mustard footbath
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
COVID-19
Povidone-Iodine Vs Essential Oil Vs Tap Water Gargling For COVID-19 Patients
The purpose of this study is to assess the ability of regular gargling to eliminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the throat and nasopharynx.
- Trial name
- GARGLES (NCT04410159)
- Testing
- Povidone-Iodine, Essential oils, Tap water
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Universiti Sains Islam Malaysia
HIV Infections
Evaluating Safety and Immune Response to the HIV-1 CH505 Transmitted/Founder gp120 Adjuvanted With GLA-SE in Healthy, HIV-exposed Uninfected Infants
This study evaluated the safety and immune response in healthy HIV-exposed and uninfected infants to the protein vaccine, CH505TF gp120, adjuvanted with GLA-SE.
- Trial name
- HVTN 135 (NCT04607408)
- Testing
- CH505TF gp120, GLA-SE adjuvant
- Where
- South Africa
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- HIV Vaccine Trials Network
Glucose Metabolism
The Effects of L-arabinose in a Meal in Healthy Men
The purpose of this study is to investigate the effect of a meal containing different doses of L-arabinose, on the intestinal sucrase activity after intake We measure this by measuring the glucose, insulin and c-peptide after…
- Trial name
- NCT01801540
- Testing
- L-arabinose - effect on glucose metabolism
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Asthma
Bronchodilatation Effects of a Small Volume Spacer Used With a Metered-Dose Inhaler
The purpose of the present study is to determine whether use of a small volume spacer is associated with better bronchodilatation in an unselected population of patients with documented reversible airflow limitations.
- Trial name
- MDI (NCT00465413)
- Testing
- Small volume spacer and/or Rinsing the mouth with water
- Where
- 2 sites in Taiwan
- Volunteers
- 300 people
- Sponsor
- Mackay Memorial Hospital
Diabetes Mellitus, Type 2
To Compare the Effects of Non-nutritive Sweeteners Intake in Subjects With T2DM
ABSTRACT Introduction: There is no current data about the effects of non-nutritive sweeteners (NNS) about important factors, such as the energy intake, appetite and its relationship in people with diabetes when tasting sweet.
- Trial name
- NCT03680482
- Testing
- Intervention ingest a 48 mg of sucralose, Intervention ingest a 96 mg of stevia
- Volunteers
- 17 people
- Sponsor
- University of Chile
Healthy
Phase I Study to Investigate Safety, Tolerability, and Pharmacokinetics of VVZ-149 Injection
VVZ-149 is a novel analgesic drug candidate that shows a potential analgesic activity inhibiting GlyT2 and 5HT2A simultaneously.
- Trial name
- P1_VVZ149IV (NCT01905410)
- Testing
- VVZ-149 Injection
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Vivozon, Inc.
Satiety Response
The Effects of Whole Versus Processed Orange Consumption on Satiety
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the…
- Trial name
- NCT02288624
- Testing
- Processed orange juice
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Reading
Peripheral Arterial Disease
Heat Therapy to Reduce Pain and Improve Walking Tolerance
The purpose of this study is to investigate whether exposure to heat therapy improves calf muscle oxygenation and enhances walking tolerance in patients with symptomatic Peripheral Arterial Disease (PAD).
- Trial name
- NCT03435835
- Testing
- Heat Therapy (HT)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Indiana University
Colorectal Cancer
RCT of Air Insufflation Versus Water Infusion Colonoscopy
Compared with the conventional (air) method, patients examined by the study (water) method have lower pain scores and require less medication but have similar cecal intubation rate and willingness to repeat future colonoscopy.
- Trial name
- NCT00785889
- Testing
- water infusion colonoscopy
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Pelvic Floor Muscle Exercise
The Clinical Role of Anogenital Distance
Aims: To evaluate the predictive value of anogenital distance (AGD) measurements, including the anus-to-clitoris distance (AGDAC) and genital hiatus (GH), on the success of pelvic floor muscle training (PFMT) in women with stress…
- Trial name
- AGD (NCT07363174)
- Testing
- Anogenital Distance Measurements, pelvic floor muscle strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Cigdem Cinar
Corona Virus Infection
Role of Mega Dose of Vitamin C in Critical COVID-19 Patients
Vitamin C (ascorbic acid) is a water-soluble vitamin having anti-inflammatory, immunomodulatory, anti-oxidative, antithrombotic and antiviral properties.
- Trial name
- NCT04682574
- Testing
- Vitamin C
- Where
- Pakistan
- Volunteers
- 278 people
- Sponsor
- University of Lahore
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