Clinical trials: Water, completed
Normal Non-fluency
Effect of Short Term Atypical Antipsychotic Administration Compared to Placebo on Hepatic Insulin Extraction
Within the past 20 years, there has been a striking increase in the incidence of obesity 1;2, type 2 diabetes mellitus (T2DM) 3-5, and cardiovascular diseases (CVD) in the schizophrenic population 6-8 .
- Trial name
- NCT02447835
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Rickels
Glycemic Index
The Effect of Content of Barley Beta-glucans in Bread on Postprandial Blood Sugar
The effect of content of barley beta-glucans in bread on postprandial blood sugar will be measured with open-label crossover study.
- Trial name
- ARRS-bGL-01 (NCT03878576)
- Testing
- REFERENCE: white bread - BGL0 [RP], TEST: b-glucan enriched bread - BGL2 [IP1], TEST: b-glucan enriched bread - BGL3 [IP2]
- Where
- Slovenia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Pulpitis, Apical Periodontitis
Clinical and Microbiological Evaluation of 0.5% Versus 3% Sodium Hypochlorite in Root Canal Treatment
Aim: To compare the clinical antimicrobial and adverse effects of irrigation with Sodium Hypochlorite (NaOCl) 0.5% versus NaOCl 3% during root canal treatment.
- Trial name
- NCT02681276
- Testing
- Irrigation with 3% NaOCl, Irrigation with 0.5% NaOCl
- Where
- Sweden
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Primary Dysmenorrhea
The Effect Of Reiki And Massage With Sage Oil On Primary Dysmenorrhea
This study was a randomized controlled trial. It included young girls with primary dysmenorrhea in a district located in the south of Turkey and was conducted between March 01, 2021 and June 30, 2021.
- Trial name
- NCT05129852
- Testing
- Sage oil group, Reiki group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Gingival Recession
Effects of the Adjunctive Use of Hyaluronic Acid-based Gel With Coranally Advanced Flap in the Gingival Recession
The study aimed to evaluate the effect of Hyaluronic Acid-based gel use in addition to the coronally advanced flap (CAF) technique in type 1 gingival recession (RT1) on postoperative morbidity, clinical parameters, and patient…
- Trial name
- NCT07437885
- Testing
- Hyaluronic acid, Steril saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ordu University
Renal Failure, Anesthesia
Renal Function During Pediatric Anesthesia
It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic…
- Trial name
- NCT02571426
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Dental Diseases
Invivo Clinical Assessment of Dimethyl Sulfoxide in OT Primer Prior to Dental Adhesive
This study is conducted to assess the clinical effectiveness of 10% Dimethyl Sulfoxide in OT Primer prior to two step etch and rinse dental adhesive on the durability of composite restoration.
- Trial name
- DMSO (NCT05090085)
- Testing
- 3M Adper Single Bond2, Filtek Z350 XT, 3 M ESPE, St Paul, MN, USA), 3m ESPE etch
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- University of Turku
Metastatic Osteosarcoma, Relapsed Osteosarcoma
Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma
This is a trial for patients affected by metastatic or relapsed osteosarcoma which progressed after first or further line treatments.
- Trial name
- SERIO (NCT01804374)
- Testing
- Sorafenib, Everolimus
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Italian Sarcoma Group
Pain, Colorectal Adenomas
A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening
Water-aided method for colonoscopy can be broadly subdivided into two major categories. Water Immersion (WI), characterized by suction removal of the infused water predominantly during the withdrawal phase of colonoscopy, and…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01780818
- Testing
- Air Insufflation method., Water Immersion method., Water Exchange method.
- Where
- 3 sites in United States, Italy
- Volunteers
- 288 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Keloid, Hypertrophic Scar
A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars
Keloids are thought to result from derailments in the typical wound healing process following cutaneous injury. Current treatment options for keloids include intralesional corticosteroids, silicone gel sheeting, compression…
- Conditions
- Keloid, Hypertrophic Scar, Cicatrix, Hypertrophic
- Trial name
- NCT00754247
- Testing
- 0.5% hydrocortisone, silicone, vitamin E lotion, Onion extract gel, Cetearyl alcohol lotion
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Puncture Site Pain
Vapocoolant Spray Effectiveness On Arterial Puncture Pain: Randomized Double Blind Placebo-Controlled Trial
This study was aimed to compare pain levels from arterial blood gas (ABG) sampling performed with vapocoolant spray in comparison to placebo.
- Trial name
- NCT01860248
- Testing
- Vapocoolant spray, Water spray
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Hypoparathyroidism
Use of NPSP558 in the Treatment of Hypoparathyroidism
Use of PTH (1-84) a recombinant hormone in escalating doses for the treatment of adults with hypoparathyroidism. The use of PTH should result in a decrease of calcium and vitamin D supplements.
- Trial name
- REPLACE (NCT00732615)
- Testing
- NPSP558
- Where
- 31 sites in United States, Belgium and 6 more
- Volunteers
- 124 people
- Sponsor
- Shire
Ketonemia
Acute Medium Chain Triglycerides (MCT) Intake in Young and Older Participants
Compare plasma metabolites following different conditions paired with a dietary MCT beverage over an 8-hour metabolic day protocol in young and older participants.
- Trial name
- Opti-MCT (NCT03830268)
- Testing
- No MCT intake with breakfast, no lunch, No MCT intake with lunch, no breakfast, 10g of Betaquik
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Burns
Effect of rFVIIa on Peri-operative Blood Loss in Patients Undergoing Major Burn
The purpose of the study is to see if a medication (Recombinant Coagulation Factor VIIa or NovoSeven), normally used to stop bleeding in persons with a bleeding disorder, will lower the amount of blood lost during burn surgery.
- Trial name
- NCT00243243
- Testing
- Recombinant Factor VIIa
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Army Institute of Surgical Research
Healthy
A Study of Selpercatinib (LY3527723) in Healthy Participants
The main purpose of this study is to determine how safe and how well tolerated selpercatinib is when given as oral doses to healthy participants.
- Trial name
- NCT05338515
- Testing
- Selpercatinib
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Blood Glucose, High
BSE on Blood Glucose
Here we will investigate the effect of sulforaphane, provided as a broccoli sprout extract (BSE) on blood glucose in pre-diabetic individuals without metformin treatment.
- Trial name
- NCT03763240
- Testing
- BSE
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Region Skane
Diet, Healthy
Effects of a High-fat Meal on Exercise-mediated Sympatholysis
The goal of this trial is to examine the effects of a single high-fat meal with or without the co-ingestion of dietary nitrate on exercise-mediated sympatholysis. The main questions it aims to answer are: 1.
- Trial name
- NCT06186050
- Testing
- Beetroot drink, Control
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Hyperglycemia, Hyperglycemia, Postprandial
NUTRACORE, Glycaemic Index and Appetite
In recent decades, the world prevalence of obesity and type 2 diabetes (DMT2) has increased dramatically, resulting in a global epidemic.
- Conditions
- Hyperglycemia, Hyperglycemia, Postprandial, Appetitive Behavior, Hyperinsulinism
- Trial name
- NTRCR-vivo (NCT05528874)
- Testing
- Same intervention for both groups: glycaemic index assessment of 3 biscuits recipes, Crossover: Recipe 4 before recipe 5, Crossover: Recipe 5 before recipe 4
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Dermatitis, Atopic
Study Of Single And Ten Day Repeat Atopical Applications Of GW842470X Cream On The Skin Of Patients With Atopic Dermatitis
The purpose of this study of this study is to investigate the safety, tolerability and pharmacokinetics of GW842470X in patients with atopic dermatitis. GW842470X is an inhibitor of phosphodiesterase 4 (PDE4).
- Trial name
- NCT00356642
- Testing
- GW842470X
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- GlaxoSmithKline
HIV Infections
A Pharmacokinetic Study to Evaluate the Effect of Antacids on Raltegravir (MK-0518) in HIV-Infected Participants (MK-0518-247)
This study will evaluate: (1) the effect of co-administration of single doses of calcium carbonate antacid and magnesium/aluminum hydroxide antacid on the steady-state plasma pharmacokinetic profile of raltegravir in human…
- Trial name
- NCT01622673
- Testing
- Raltegravir, TUMS® Ultra Strength, MINTOX® Maximum Strength
- Volunteers
- 27 people
- Sponsor
- Merck Sharp & Dohme LLC
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