Clinical trials: Water
Fasting
Effects of Prolonged Fasting on Microbiome and HDL
Participants will undergo one day of habitual eating followed by 36 hours of water only fasting and final day of habitual eating of the exact same diet consumed on the first eating day.
- Trial name
- NCT03487679
- Testing
- Fasting
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Relapsed/Refractory Multiple Myeloma
A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy
This was a Phase 3, multicenter, randomized, double blind, placebo-controlled study evaluating the efficacy and safety of venetoclax plus bortezomib and dexamethasone in participants with relapsed or refractory multiple myeloma…
- Trial name
- Bellini (NCT02755597)
- Testing
- Venetoclax, Bortezomib, Dexamethasone
- Where
- 97 sites in United States, Australia and 14 more
- Volunteers
- 291 people
- Sponsor
- AbbVie
Obesity, Gastroesophageal Reflux
Ultrasound Assessment for Comparison of Gastric Residual Volume After Ingestion of Carbohydrate Drink and Water in Obesity Class II and III Volunteers at Risk of Aspiration
The goal of this clinical trial is to compare gastric residual volume between drinking a carbohydrate drink and water in obesity class II and III volunteers at risk of aspiration.
- Trial name
- CarbDrinkUltra (NCT06941623)
- Testing
- Ultrasonography of gastric residual volume, Point-of-care testing of glucose, Hunger numeric rating scale
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Diabetes Prevention, Obesity Prevention
Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children
The purpose of this study is to examine the effects of fluid dairy products on blood glucose and insulin, satiety and energy intake in normal weight and overweight/obese children in the age range of 9-14 y.
- Trial name
- NCT02147496
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Acute Lymphoblastic Leukemia
Rapamycin in Relapsed Acute Lymphoblastic Leukemia
This is a research study designed to look at the biological effects of two drugs on leukemia cells. In this study, we are comparing the effects of drugs called corticosteroids when used alone or with another drug called…
- Trial name
- NCT00874562
- Testing
- Corticosteroid, Rapamycin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Dana-Farber Cancer Institute
Caries Infiltration, Fluorosis
Resin Infiltration and Resin Infiltration With Bleaching in Improving the Esthetics for Fluorosis Stains
Dental fluorosis is a clinical manifestation of chronic exposure to high intakes of fluoride during the tooth development. The present study is planned to evaluate the efficacy of Resin Infiltration technique in improving the…
- Conditions
- Caries Infiltration, Fluorosis, Dental Care
- Trial name
- NCT01733888
- Testing
- Office Bleaching, Resin Infiltration, Resin Infiltration twice
- Where
- 2 sites in India
- Volunteers
- 80 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
High Grade Ovarian Serous Adenocarcinoma, Stage III Ovarian Cancer AJCC v8
Lavage of the Uterine Cavity for Diagnosis of Ovarian Cancer
The goal of this project is to develop a minimally invasive test to detect ovarian cancer, by searching for mutations from the tumor in samples obtained from the cervix (Pap smears), and from the uterus (uterine lavage) in…
- Conditions
- High Grade Ovarian Serous Adenocarcinoma, Stage III Ovarian Cancer AJCC v8, Stage IIIA Ovarian Cancer AJCC v8, Stage IIIA1 Ovarian Cancer AJCC v8
- Trial name
- NCT03606486
- Testing
- Biospecimen Collection, Laboratory Biomarker Analysis, Lavage
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Washington
Open Wound, Wound Heal
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
The purpose of this study is to assess the safety and efficacy of Micro/nanobubbles (MNB's) for the healing of acute and chronic wounds.
- Trial name
- MNB (NCT05169814)
- Testing
- Micro/nanobubble (MNB) - Irrigation, 0.9% Normal Saline - Irrigation, Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Tibial Meniscus Injuries, Knee Injuries
Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty Military
Knee injuries are common among active-duty military personnel. One of the most common knee injuries is a meniscus tear, which can have several consequences.
- Conditions
- Tibial Meniscus Injuries, Knee Injuries, Knee Injuries and Disorders
- Trial name
- NCT04274543
- Testing
- Lipogems, Normal Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Kessler Foundation
Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage
Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section
This study aims to define a safe prophylactic intravenous TXA dose with an advantage over others in reducing total blood loss volume at secondary uncomplicated LSCS.
- Trial name
- NCT02739815
- Testing
- Normal Saline containing a prophylactic Antibiotic 1 g, Tranexamic Acid
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Talkha Central Hospital
Body Weight
Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water
Sugar-sweetened beverages (SSBs) contribute an alarming ~7% of calories in the US diet among adults, making SSBs the single largest source of added sugar.
- Trial name
- SUB-POP (NCT04567108)
- Testing
- Maintain usual SSBs, Substitute to non-SSBs, Study app
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dysphagia
Yale Swallow Protocol in Extubated Patients
The purpose of this study is to determine if the Yale Swallow Protocol is an effective screen for aspiration in recently extubated patients.
- Trial name
- NCT03352908
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of Wisconsin, Madison
Stable Chronic Heart Failure
CD-NP in Subjects With Stable Chronic Heart Failure
This human physiologic study will evaluate the effects of a new drug called CD-NP in individuals with stable chronic heart failure, with a focus on evaluating responses of the kidneys and the hormonal system.
- Trial name
- CD-NP (NCT00620308)
- Testing
- CD-NP
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mayo Clinic
Cannabis Intoxication, Alcohol Intoxication
Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment
This human laboratory study will use cognitive, behavioral, and subjective measures to characterize impairment associated with co-use of alcohol and vaporized cannabis.
- Trial name
- NCT06293040
- Testing
- Cannabis, Alcohol
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Phenylketonuria
A Study of PTC923 in Participants With Phenylketonuria
The main purpose of this trial is to evaluate the efficacy of PTC923 in reducing blood phenylalanine (Phe) levels in participants with phenylketonuria as measured by mean change in blood Phe levels from baseline to Weeks 5 and 6…
- Trial name
- NCT05099640
- Testing
- PTC923
- Where
- 43 sites in United States, Australia and 13 more
- Volunteers
- 157 people
- Sponsor
- PTC Therapeutics
Healthy
Effect of Various Processed Oat Bran in a Beverage Matrix on Glycaemic Health
Whilst a cause-and-effect relationship between consumption of oat ß-glucans and reduction in PPGR has been demonstrated, little is understood about its: Application to liquid matrices: There are few studies which looked into the…
- Trial name
- NCT04930250
- Testing
- Beverage powder with 12% oat bran processed with method A, Beverage powder with 12% oat bran processed with method B, Beverage powder with 12% oat bran processed with method C
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Dentine Hypersensitivity
A Study to Evaluate the Dentinal Hypersensitivity Efficacy of Two Experimental Mouthwash Formulations
The aim of this study is to evaluate the clinical efficacy of two experimental mouthwash formulations, against a placebo mouthwash (without experimental ingredients).
- Trial name
- NCT07741032
- Testing
- 3% KNO3 Mouthwash, 2% HPC Mouthwash, 0% KNO3 Mouthwash
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- HALEON
Unconscious State
The Effect of Auditory Stimulation and the "Love Glove" Technique
The aim of this study was to determine the effect of the "love glove" intervention, combined with the voices of family members and nurses, on vital signs in unconscious patients in the intensive care unit.
- Trial name
- NCT07602998
- Testing
- Voice of a patient's relative, Voice of nurse, Love glove
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Manisa Celal Bayar University
Gingivitis, Dental Plaque
The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis
This study aims to evaluate the effect of novel mouthrinse formulations containing bamboo salt, magnolia bark and centella asiatica extracts on gingivitis and dental plaque.
- Trial name
- NCT03047798
- Testing
- Mouthrinse
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Chemotherapy Induced Nausea and Vomiting
This Study Will Investigate the Effectiveness of Peppermint Oil Inhalation in Reducing the Intensity and Frequency of Acute Nausea and Vomiting Among Cancer Patients Undergoing Chemotherapy. Chemotherapy-induced Nausea and Vomiting (CINV) Are Among the Most Distressing Side Effects Experienced by pa
Cancer is a major cause of death and disability worldwide and in South Asian countries. Cancer treatment options include chemotherapy, radiation therapy, surgery, and adjuvant therapy (Additional treatments after primary cancer…
- Trial name
- NCT06950632
- Testing
- Pepppermint oil inhalation
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- University of Health Sciences Lahore
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