Clinical trials: Water
Water-Related Diseases
SAFEWATER Health & Behaviour Impact Field Trials; Mexico
At least 1.8 billion people globally use a source of drinking water that is faecally contaminated and thus likely to lead to diarrheal illness: nearly 1,000 children die each day due to water and sanitation-related diarrhoeal…
- Trial name
- NCT04736615
- Testing
- SAFEWATER systems for drinking water disinfection, Behavior change interventions
- Where
- 3 sites in Colombia, Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Caffeine, Placebo
Acute Caffeine Ingestion on Futsal Performance
Caffeine supplementation has been recognized such as an useful strategy for improving performance in intermittent sports, however caffeine ingestion in futsal has been barely studied.
- Trial name
- CAFFFUTSAL (NCT04852315)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Endothelial Dysfunction, Nutritional Status
Effect of Non-alcoholic Beer in Cirrhosis
The implementation of nutritional strategies targeting several variables at once could benefit patients with cirrhosis. Non-alcoholic beer has different compounds derived from hops that exert antioxidant, anti-inflammatory and…
- Conditions
- Endothelial Dysfunction, Nutritional Status, Quality of Life
- Trial name
- LFN-NAB (NCT04041115)
- Testing
- Non-alcoholic beer, control
- Volunteers
- 42 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Hypoparathyroidism
Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism
The purpose of this study is to investigate the safety and tolerability of MBX 2109 administered once weekly to patients with hypoparathyroidism.
- Trial name
- NCT06465108
- Testing
- MBX 2109
- Where
- 33 sites in United States, Argentina and 1 more
- Volunteers
- 64 people
- Sponsor
- MBX Biosciences
Pulmonary Congestion
Thoracic Fluid Assessment by Contrast-enhanced Magnetic Resonance Imaging and Bioimpedance
Heart failure (HF) is a major health problem, which is characterized by reduced cardiac function leading to pulmonary congestion. Most episodes of acute HF requiring unplanned hospitalization are due to pulmonary congestion.
- Trial name
- NCT02364193
- Testing
- MRI, Gd-CA, BIS ImpediMed™ SFB7
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Gingivitis, Periodontitis
Alcohol-free Essential Oils Containing Mouthrinse Efficacy on 3-day Supragingival Plaque Regrowth
The purpose of this study is to evaluate the antiplaque effects of an alcohol-free essential-oil containing mouthrinse - Listerine Zero (LZ) and an alcohol-based essential oils (EO+) mouthwash compared to a positive control of…
- Trial name
- NCT02894593
- Testing
- alcohol free essential oils mouthwash, alcohol essential oils mouthwash, 0.20% chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Smoking, Smoking Cessation
Message Testing in Older Adult Smokers
This study is examining different messages to motivate older smokers to quit smoking. Participants will be current smokers, between the ages of 50-80 years old, who do not have a history of cognitive impairment or dementia.
- Trial name
- NCT05471349
- Testing
- Flyer and video
- Where
- United States
- Volunteers
- 820 people
- Sponsor
- University of Wisconsin, Madison
Obesity
Nicotinamide Riboside and Mitochondrial Metabolism
Vitamin B3 has recently been found to be a potent modifier of energy metabolism, especially the function of mitochondria. Mitochondria power up all cells in our bodies, by generating fuel, ATP, for cellular functions.
- Trial name
- VitaPower (NCT03951285)
- Testing
- NR in BMI-discordant twins, NR in BMI-concordant twins
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training Combined With General Exercise Training in COPD
Chronic Obstructive Pulmonary Disease (COPD) is a frequent disease, with increasing prevalence. Pulmonary rehabilitation through general exercise training (GET) is a corner stone of COPD care.
- Trial name
- IMTGET (NCT02392715)
- Testing
- Inspiratory muscle training with Threshold by respironics
- Volunteers
- 80 people
- Sponsor
- Hôpital Riviera-Chablais, Vaud-Valais
Moderate to Severe Bronchiolitis
Moderate to Severe Bronchiolitis: Standard Therapy Versus Therapy With NaCl 3% Inhalations
Our study will investigate inhalation therapy of NaCl 3% compared to standard therapy with no inhalation in the treatment of moderate to severe bronchiolitis. The impact on length of hospital stay will be analyzed.
- Trial name
- NCT01812525
- Testing
- NaCl 3%, Standard therapy
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Raphaelle Jaquet-Pilloud
Multiple Myeloma, Venous Thromboembolism (VTE)
Aspirin vs. Rivaroxaban for Thromboprophylaxis in Multiple Myeloma
The goal of this clinical trial is to compare the efficacy and safety of aspirin versus rivaroxaban for thromboprophylaxis in newly diagnosed multiple myeloma patients receiving immunomodulatory drug (IMiD)-based therapy.
- Trial name
- NCT07907211
- Testing
- Aspirin, Rivaroxaban
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chen Lijuan
Satisfaction, Quality of Life
Effect of Occlusal Accommodation of the Mouthguard on the Degree of Satisfaction of Water Polo Players
This study assesses the effect of adjusting the occlusal surface of a custom-made mouthguard on the degree of satisfaction with a mouthguard among water polo players.
- Trial name
- NCT03845621
- Testing
- Conventional Mouthguard, Occlusal-adjusted Mouthguard
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Major Depressive Disorder
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
The goal of this clinical trial is to learn if ABX-002 added to an existing antidepressant treatment will benefit depression symptoms in adults with moderate to severe major depressive disorder who have had an inadequate response…
- Trial name
- NCT06633016
- Testing
- ABX-002
- Where
- 50 sites in United States
- Volunteers
- 230 people
- Sponsor
- Autobahn Therapeutics, Inc.
Knee Osteoarthritis, Primary Total Knee Arthroplasty
Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.
The purpose of this study is to learn if using an Interspace between the Popliteal Artery and Capsule of the Knee (iPACK) injection technique (also called a "nerve block") that numbs the nerves going to the back part of the knee…
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain
- Trial name
- NCT03353233
- Testing
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Exercise Nutritional Physiology
Influence of Dietary Nitrate on Time Trial Performance in Swiss Paracycling Athletes
The aim of this study is to investigate wether beetroot juice or sodium nitrate enhances time trial performance in Swiss paracycling athletes compared to the ingestion of a placebo supplement.
- Trial name
- nitrate_TT (NCT02454049)
- Testing
- beetroot juice, sodium nitrate, water
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Different Fermentable Fiber, Satiation
The Effect of Dietary Fiber on Food Liking
This study will investigate the effects of different fermenting fibers on liking of foods.
- Trial name
- NCT03241238
- Testing
- Eating
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Persistent Pulmonary Hypertension
Efficacy and Safety of Milrinone Versus Sildenafil in the Treatment of Neonates With Persistent Pulmonary Hypertension
Compare the effect of milrinone versus sildenafil in treatment of neonates with persistent pulmonary hypertension.
- Trial name
- ESMPPHTN (NCT04391478)
- Testing
- Milrinone, Sildenafil
- Volunteers
- 40 people
- Sponsor
- Rania Ali El-Farrash
Elderly Women
Effects of Water-based Aerobic and Combined Training in Elderly Woman
Purpose: Investigate neuromuscular, cardiorespiratory, functional capacity, quality of life and cognitive adaptations of eight weeks of water-based aerobic and combined training in elderly women previously trained for eight weeks…
- Trial name
- ACTIVE (NCT03892278)
- Testing
- Water-based aerobic training, Water-based aerobic and combined training, Control group
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Vaginal Atrophy, Postmenopausal Symptoms
Vaginal Dehydroepiandrosterone (DHEA) in Postmenopausal Breast Cancer Survivors on Aromatase Inhibitors
The purpose of this research is to gather information on the safety and effectiveness of Intrarosa®, also known as Dehydroepiandrosterone (DHEA), and prasterone.
- Conditions
- Vaginal Atrophy, Postmenopausal Symptoms, Breast Cancer Female, Long-term Survivors
- Trial name
- NCT04493333
- Testing
- Vaginal Dehydroepiandrosterone, Vaginal Polycarbophil Moisturizer
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Arkansas
Caloric Intake and Energy Metabolism
Assessment of Energy Balance
The primary purpose of this study is to test different methods of measuring energy balance, including food intake and energy expenditure.
- Trial name
- EnergyBalanc (NCT01678885)
- Testing
- Digital Photography of Foods, doubly labeled water, IDEEA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Pennington Biomedical Research Center
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