Clinical trials: Water
Dermatitis, Atopic
Effect of Different Skin Creams on TEWL
Prospective, single center, clinical pilot study to test the hypothesis that lipid rich EpiCeram® is superior in improving skin barrier function compared to Aveeno Daily Moisturising Sheer Hydration Lotion®.
- Trial name
- NCT03663673
- Testing
- EpiCeram, Aveeno Daily Moisturising Sheer Hydration Lotion®
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Stanford University
Enteral Feeding, Nasogastric Feeding
Effects of Bolus and Continuous Nasogastric Feeding on Small Bowel Water Content and Blood Flow
Following surgery some patients are unable to swallow. For those requiring nutritional support a tube is sometimes passed through the nose into the stomach to provide feeding.
- Conditions
- Enteral Feeding, Nasogastric Feeding, Diarrhoea
- Trial name
- NCT01557673
- Testing
- NG bolus feeding over 5 min, Continuous NG feeding over 4 h
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Benign Prostatic Hyperplasia (BPH)
REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men
The study objective is to compare water vapor thermotherapy with the REZŪM™ System to dual drug therapy for the treatment of symptomatic benign prostatic hyperplasia refractory to alpha-blocker monotherapy in sexually active men.
- Trial name
- VAPEUR (NCT04838769)
- Testing
- REZŪM, alpha blocker and 5-alpha reductase inhibitor
- Where
- 21 sites in Australia, France
- Volunteers
- 155 people
- Sponsor
- Boston Scientific Corporation
Caries, Dental
Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
The aim of this study is to determine the effectiveness of Er:YAG pulse therapy for achieving pulpal analgesia in pediatric patients and to quantify the duration and extent of any effects assessed.
- Trial name
- NCT03412721
- Testing
- Laser analgesic procedure
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Effect of Food
Nutrient Profile and Muscle Protein Synthesis in Response to Corn Bread Made From Refined Versus Whole Grain Maize Flour
The purpose of the study is to quantify and compare the serum nutrient and hormonal profile, and muscle protein synthesis rates, in response to consuming isonitrogenous amounts of a traditional East African meal, mung bean stew…
- Trial name
- PRO-CORN (NCT06662214)
- Testing
- Refined maize flour, Whole grain flour
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sepsis
Validation of a Capillary Leak Index During Septic Shock, Based on Haemoglobin Level Variations Induced by Fluid Resuscitation. A Pilot Study.
This study aims to validate a simple and reproducible index of capillary leak (CLI) in septic shock, based on haemoglobin (Hb) variation induced by standardised fluid resuscitation.
- Trial name
- IFC-sepsis (NCT07733206)
- Testing
- TEST GROUP: A standardised fluid bolus of 8 mL/kg of ideal body weight using Ringer's lactate will be administered in septic shock patients., CONTROL GROUP: A standardised fluid bolus of 8 mL/kg of ideal body weight using Ringer's lactate will be administered in non-septic postoperative patients.
- Where
- Martinique
- Volunteers
- 100 people
- Sponsor
- University Hospital Center of Martinique
Acute ST Elevation Myocardial Infarction
Nitrites in Acute Myocardial Infarction
The research question to be addressed is "Does a 2.5 - 5 minute systemic intravenous injection of sodium nitrite administered immediately before opening of the infarct related artery result in significant reduction of ischaemia…
- Trial name
- NIAMI (NCT01388504)
- Testing
- sodium nitrite
- Where
- 3 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Aberdeen
Major Abdominal Surgeries
Cold Water Gargling After Major Abdominal Surgery
This randomized controlled trial examined the effect of cold water gargling on postoperative oral dryness, thirst severity, and patient satisfaction in patients who underwent major abdominal surgery.
- Trial name
- NCT07506226
- Testing
- Cold water gargling
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- TC Erciyes University
Peri-implant Mucositis
Management of Peri-implant Mucositis With Ozone Water Jet: a Randomized Clinical Trial.
The aim of this study is to assess if ozonized water can be used for the treatment of peri-implant mucositis in patients with dental implants.
- Trial name
- NCT04845087
- Testing
- Ozonized water
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Pavia
Nutritional Wasting, Nutritional Stunting
Ifaa Effectiveness Evaluation on Food Security and Nutrition
The Ifaa Project is a USAID-funded Resilience and Food Security Activity (RFSA) that is being implemented by Catholic Relief Services (CRS) and partners in the East Hararghe Zone of the Oromia Region in Ethiopia.
- Trial name
- NCT05825716
- Testing
- Ifaa Basic, Ifaa Enhanced, Ifaa Enhanced + Livelihoods
- Where
- Ethiopia
- Volunteers
- 3,317 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Thyroid; Functional Disturbance
Photodegraded Edible Food Dyes
Assess and contrast the effect of erythrosine and photodegraded erythrosine on thyroid function. Thyroid function will be evaluated as serum triiodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH), T3 resin…
- Trial name
- NCT04708704
- Testing
- Erythrosine, prepared in drinking water (0.69 mg/kg bw/day), SODIS-treated erythrosine, prepared in drinking water (0.69 mg/kg bw/day), Iodine, prepared in drinking water 0.075 mg/kg bw/day)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Anemia
The Invisible Fishers
This pilot study aims to introduce three interventions directed toward mitigating anemia among women in Ghana, including: 1) multi-sectoral behavior change, 2) strengthening market engagement of fish processors, 3) improving fish…
- Trial name
- NCT03498755
- Testing
- Mobile phone audio messaging, Peer-to-peer learning, Conditional cash transfer
- Where
- Ghana
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pulmonary Arterial Hypertension
Effect of Food on BIA 5-1058
The aim of this study is to investigate the effect of food on the pharmacokinetic (PK) profile of BIA 5-1058 after a single dose in healthy subjects.
- Trial name
- NCT04991155
- Testing
- BIA 5-1058
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity
A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants
This is a randomized, open-label, multiple-dose study to evaluate the effects of different volumes of administration water, post-dose fasting duration, and high-fat diet on the pharmacokinetics of the 15 mg dose of MWN109 tablets…
- Trial name
- NCT07801326
- Testing
- MWN109 Tablets
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Hip Fracture Surgeries
The Effect of Abdomınal Massage and Warm Water Consumptıon on Postoperatıve Constıpatıon Development and Qualıty of Recovery in Patıents Undergoıng Hıp Fractures Surgery
There is a need for studies investigating the effects of abdominal massage and warm water consumption on the development of postoperative constipation and quality of recovery in patients who have undergone hip fracture surgery.
- Trial name
- NCT07437014
- Testing
- ABDOMINAL MASSAGE AND WARM WATER CONSUMPTION, abdominal massage, Control (Standard treatment)
- Volunteers
- 81 people
- Sponsor
- Hacettepe University
NAFLD
Healthy Eating Through Reduction Of Excess Sugar
The purpose of the study is to determine the effect of dietary sugar reduction in obese children and examine whether there are differential effects based on genotype of a single amino acid substitution in the PNPLA3 gene that is…
- Trial name
- HEROES (NCT02948647)
- Testing
- Standard of care plus sugar-reduction education
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- University of Southern California
Smoking Cessation, Weight Loss
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
The purpose of this research study is to better understand (1) why people gain weight when they quit smoking and (2) whether certain types of smoking cessation (i.e.
- Trial name
- NCT02906787
- Testing
- BAS+, SC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Healthy
The Effects of Dietary Supplementation on Serum Protein Glycosylation
Two randomized double-blind placebo-controlled clinical studies to assess the effects of dietary glycan monomer supplementation on the immune system, especially antibody glycosylation in healthy adults.
- Trial name
- NCT05040204
- Testing
- Monosaccharide Powder
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Diabetes Mellitus, Type 2, Overweight and Obesity
A Clinical Trial of Overweight/Obesity With Type 2 Diabetes
In the previous intervention studies of Type 2 Diabetes Mellitus patients, changes in blood glucose and insulin resistance profiles before and after intervention indicated that different intervention methods had different effects…
- Trial name
- ELFOOD (NCT03972904)
- Testing
- Light-Fat Rice® combined with Active Peptide®+ lifestyle guidance, A staple food of comparable energy containing a small amount of dietary fiber combined with a comparable energy maltodextrin + lifestyle guidance
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Peking Union Medical College Hospital
Endothelial Dysfunction
Effect of Chlorogenic Acids on the Human Vasculature
This study evaluates effects of different doses of chlorogenic acids on vascular health.
- Trial name
- NCT03520452
- Testing
- Green coffee extract
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
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