Clinical trials: Water, completed
Healthy Nutrition
Studying Glucose and Appetite Response With Alternatives to Soda Pop
The primary aim of this clinical trial is to determine the acute effects of OLIPOP (a lower sugar, high fiber prebiotic soda) consumption, compared to consumption of a commercially available sugar-sweetened soda pop, on blood…
- Trial name
- SODA-SWAP (NCT06427915)
- Testing
- OLIPOP prebiotic soda, Traditional sugar-sweetened cola
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Olipop, PBC
Cervical Lesion
Bioactive Glass Air-abrasion and Non-carious Cervical Lesions
Evaluating the clinical behavior of composite restorations in NCCLs when the surface is pre-conditioned using bioactive glass air-abrasion has not been reported in the dental literature.
- Trial name
- NCT04578717
- Testing
- Air-abrasion, Adhesive application - Etch&rinse, Adhesive application - Self-etch
- Where
- Syria
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Damascus University
Obesity, Adolescent, Pre Diabetes
Effect of NNS on Metformin/GDF15, Pilot
Metformin use for diabetes has the benefit of causing weight loss in some. The investigators in a preclinical trial, demonstrated that mice consuming non-nutritive sweetened (NNS) drinks had worse glucose improvements and weight…
- Trial name
- NCT05400863
- Testing
- avoid sugary and NNS drinks plus start Metformin, avoid sugary drinks (allowed water and drinks sweetened with NNS) plus start Metformin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Infection, Human Immunodeficiency Virus
Effect of Rifampin (RIF) on the Pharmacokinetics (PK) of Oral Cabotegravir (CAB) in Healthy Subjects
CAB is an integrase inhibitor that is currently in Phase 2 clinical trials for the treatment and prevention of human immunodeficiency virus-1 (HIV-1) infection.
- Trial name
- NCT02411435
- Testing
- CAB, RIF
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Healthy
A Pilot Study of the Safety, Tolerability, and Effectiveness of Halo
This is a pilot study of the safety, tolerability, and effectiveness of Halo to prevent acute upper respiratory illness and respiratory virus infections.
- Trial name
- NCT02644135
- Testing
- Halo Oral Spray
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Iron Deficiency Anemia, Anemia
Iron Fish in Dominican Republic (DR) Children
The objective of the study is to assess the acceptability, feasibility, and barriers to Lucky Iron Fish™ (LIF) utilization among families with young children in a Latin American community with a high prevalence of iron deficiency…
- Conditions
- Iron Deficiency Anemia, Anemia, Iron-deficiency
- Trial name
- NCT03199235
- Testing
- Lucky Iron Fish, enhanced standard of care
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Herpes Zoster
The Safety and Immunogenicity Study of the Recombinant Zoster Vaccine (CHO Cell)
This is a randomized, observer-blinded, active-controlled Phase I study to evaluate the safety, reactogenicity, and immunogenicity of REC610, when administered as 2 intramuscular (IM) injections in healthy adults aged 40 years…
- Trial name
- NCT05769049
- Testing
- REC610, Shingrix
- Where
- Philippines
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiangsu Rec-Biotechnology Co., Ltd.
Persian Gulf Syndrome, Chronic Sinusitis
Gulf War Illness Nasal Irrigation Study
The purpose of this study is to determine whether nasal irrigation with Xylitol or saline are effective in the treatment of chronic rhinosinusitis and fatigue symptoms associated with Gulf War Illness.
- Conditions
- Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
- Trial name
- GWINIS (NCT01700725)
- Testing
- Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Patients With Severe Chronic Kidney Disease Being Evaluated With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson
Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging
The routine administration of 75 mg of intravenous aminophylline in patients with severe chronic kidney disease undergoing a nuclear stress test with regadenoson (Lexiscan®) can reduce or eliminate the incidence of diarrhea and…
- Trial name
- ASSUAGE-CKD (NCT01336140)
- Testing
- Aminophylline
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Rush University Medical Center
Healthy
The Effect of Semaglutide on Pituitary Function
The primary aim of the study is to describe the effect of a single oral dose of semaglutide 7 mg on growth hormone secretion.
- Trial name
- NCT04865744
- Testing
- Semaglutide 7 MG Oral Tablet, Semaglutide 14 MG Oral Tablet
- Where
- Estonia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Gingivitis, Dental Plaque
The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis
This study aims to evaluate the effect of novel mouthrinse formulations containing bamboo salt, magnolia bark and centella asiatica extracts on gingivitis and dental plaque.
- Trial name
- NCT03047798
- Testing
- Mouthrinse
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Hyperthermia, Thermoregulation
Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion
As overheating in buildings is expected to increase as global warming continues, proactive measures to increase heat resiliency in heat-vulnerable older people are needed, especially for those without access to home cooling or…
- Conditions
- Hyperthermia, Thermoregulation, Aging, Heat Acclimation and Thermotolerance
- Trial name
- NCT06670365
- Testing
- Heat acclimation by warm-water immersion
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Ventilator Associated Pneumonia
Oral Care Interventions and Ventilator Associated Pneumonia in Critically Ill Children
This experimental study aims to verify the influence of the oral hygiene performance with chlorhexidine digluconate 0.12% in the development of VAP in children.
- Trial name
- NCT01083407
- Testing
- 0.12% Chlorhexidine Digluconate, Toothbrushing
- Volunteers
- 146 people
- Sponsor
- Federal University of São Paulo
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Long-term Follow-up
This study extends follow up on of Native American (NA) mothers and their children (now age 3-5 years) enrolled in the 1:1 randomized controlled trial of the Family Spirit Nurture (FSN) intervention designed to prevent early…
- Conditions
- Obesity, Water; Lack of, Childhood Obesity, Feeding Behavior
- Trial name
- PECO1-LTF (NCT05424471)
- Testing
- Family Spirit Nurture (FSN), Control Group - Vehicle Safety
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Bioavailability
Study on Sapropterin Dihydrochloride Oral Suspension in Healthy Subjects
This is a single center, Phase 1, randomized, open-label, single-dose, 4 treatment, 4-period, 4-sequence, crossover study designed to compare the pharmacokinetics (PK) of sapropterin from the Test and Reference products, and to…
- Trial name
- NCT06481709
- Testing
- RLF-OD032, Kuvan
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- APR Applied Pharma Research s.a.
Muscle Function, Muscle Soreness
Vitamin D2, Muscle Damage, NASCAR Pitcrew
Hypothesis: Six weeks of supplementation with vitamin D (4000 IU/day) using Dole's Vitamin D Portobello Mushroom Powder will increase winter serum vitamin D levels, and improve muscle function and strength, and innate immunity…
- Conditions
- Muscle Function, Muscle Soreness, Vitamin D Status
- Trial name
- NCT01825616
- Testing
- Vitamin D2 mushroom powder
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Vaginal Microbiome
Influence of Probiotics on the Vaginal Microbiota
The study aims to assess the influence of a probiotic supplement (OMNi-BiOTiC® FLORA plus +) on the vaginal microbiome composition of women suffering from infertility.
- Trial name
- NCT04471116
- Testing
- OMNi-BiOTiC® FLORA plus+
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Kinderwunsch Institut GmbH
Premenstrual Syndrome
The Effect of Hydrogen-rich Water on Premenstrual Symptoms and Quality of Life
The aim of this study is to determine the effect of hydrogenated water on premenstrual symptoms and quality of life in students with premenstrual syndrome.
- Trial name
- NCT05556252
- Testing
- Hydrogenated water consumption, Drinking water consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Menekşe Nazlı AKER
Systemic Sclerosis
Ultrasound Therapy and Manual Therapy in Digital Ischemic Ulcers
The objective of this before-after non-randomized trial study is to evaluate the efficacy of ultrasound therapy in combination with manual therapy in the management of systemic sclerosis patients with IDU.
- Trial name
- NCT05907200
- Testing
- combination ultrasound therapy and manual therapy, manual therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University of Palermo
Chronic Kidney Failure
Furosemide and Creatinine Tubular Stress Test in Order to Measure Proximal Tubule Residual Function
This is a two phase study. The first part will take place at the National Institute of Cardiology in Mexico, the second phase will be made in collaboration with the University of California San Diego and University of Minnesota.
- Trial name
- NCT05105009
- Testing
- Furosemide Injection, Creatinine Powder, Iohexol
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
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