Clinical trials: Water, completed
Gingivitis
A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen
The study will determine the effects of adding mechanical plaque control to a person's oral care regimen. Participants who qualify to participate in the study will will have an equal chance of being assigned to one of three…
- Trial name
- NCT01419626
- Testing
- Interdental cleaning device with water, Interdental cleaning device with essential-oil mouthrinse
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Advanced Solid Malignancies, Non-Small Cell Lung Cancer (NSCLC)
A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies
This is a Phase 1, open-label, multicenter study of continuous oral dosing of AZD4635 administered to patients with advanced solid malignancies.
- Conditions
- Advanced Solid Malignancies, Non-Small Cell Lung Cancer (NSCLC), Metastatic Castrate-Resistant Prostate Carcinoma (mCRPC), Colorectal Carcinoma (CRC)
- Trial name
- NCT02740985
- Testing
- AZD4635, Durvalumab, Abiraterone Acetate
- Where
- 17 sites in United States
- Volunteers
- 313 people
- Sponsor
- AstraZeneca
Hyperthermia
Cold Water Immersion Stirring in Hyperthermic Individuals
The best way to cool a very hot person is using cold water immersion, however, the optimization of this technique has not been established.
- Trial name
- NCT04613843
- Testing
- Water Stirring, No Water Stirring
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Breast Cancer
Aquatic Versus Land Based Exercise on Lymphedema Post Mastectomy
Fifty eligible breast cancer survivors (median, 10 yrs after surgery) with arm lymph-edema (median, 21% inter limb difference) were included and randomized into the intervention(group A, n = 25) or control ( Group B, n = 25).
- Trial name
- NCT04257643
- Testing
- aquatic based exercise., land-based exercise.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Necrotizing Enterocolitis
Probiotics to Prevent NEC - a Historical Control Study
Probiotics is given routinely to infants admitted to the department of neonatology during the first 3 days of life with gestational age less than 30 weeks since March 2010.
- Trial name
- NCT01670916
- Testing
- probiotics
- Where
- Denmark
- Volunteers
- 714 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
C. Difficile
Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile
Clostridioides difficile (C. difficile) is the most common healthcare-associated pathogen, causing >500,000 infections and >29,000 deaths per year in the US.
- Trial name
- NCT05389904
- Testing
- Arm 1: Routine care, Arm 2: Preemptive C. difficile infection prevention bundle
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Brigham and Women's Hospital
Caries, Dental
Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
The aim of this study is to determine the effectiveness of Er:YAG pulse therapy for achieving pulpal analgesia in pediatric patients and to quantify the duration and extent of any effects assessed.
- Trial name
- NCT03412721
- Testing
- Laser analgesic procedure
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Healthy
Cross-over Study to Evaluate the Palatability of New Orally Disintegrating Tablets (ODTs) of Praziquantel (PZQ) and L-PZQ Versus Current PZQ Tablets in African Children Age 6-11 Years
The primary objective of the trial is to compare the "overall palatability" of the new orally disintegrating L-Praziquantel (L-PZQ ODT), the new racemate PZQ ODT (Rac-PZQ ODT) and the current available racemate PZQ tablets…
- Trial name
- NCT02315352
- Testing
- L-PZQ ODT, Rac-PZQ ODT, Cesol®
- Where
- Tanzania
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Liver Neoplasms
Percutaneous Microwave Ablation Under Ultrasound Guidance for Liver Cancer: a Multicenter Analysis
Ultrasound-guided percutaneous MWA of liver cancer is a relatively new technique with favorable long-term outcomes.Butthe results are mainly from single center reports.A larger scale data need to be analyzed to evaluate the…
- Trial name
- NCT03045952
- Testing
- microwave ablation device
- Where
- China
- Volunteers
- 1,908 people
- Sponsor
- Chinese PLA General Hospital
Celiac Disease
A Study to Investigate the Pharmacokinetics, Pharmacodynamic Effects, Safety and Tolerability of Repeated Dosing of RO5459072 in Volunteers With Celiac Disease
A randomized, double-blind, placebo-controlled, two treatment, parallel group study to investigate the effects of RO5459072, a cathepsin S inhibitor, on the immune response to a gluten challenge in volunteers with celiac disease.
- Trial name
- NCT02679014
- Testing
- RO5459072
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Hoffmann-La Roche
Healthy
Effects of FODMAPs on Small Bowel Water Content: an MRI Study
Some carbohydrates, particularly fructose, the sugar found in fruit and bread may cause bloating, pain and erratic bowel habits (diarrhoea and constipation) particularly in patients suffering from the irritable bowel syndrome…
- Trial name
- FODMAPs (NCT01459406)
- Testing
- Glucose, Fructose, Fructan
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
PostTraumatic Stress Disorder
Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder
The tasks of the project are to map the potency and kinetics of the neurologic, autonomic peripheral, inflammatory, and behavioral responses to vagal nerve stimulation (VNS) vs.
- Trial name
- NCT02992899
- Testing
- GammaCore/electroCore non-invasive VNS device, O-15 water
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Emory University
Colon Cancer, Lymphatic Metastasis
Sentinel Node Mapping With Indocyanine Green in Colon Cancer: a Feasibility Trial and a Descriptive Serie.
This study is a clinical feasibility trial that will contribute to the clarification of whether sentinel node mapping with indocyanine green (ICG) provides a better basis for staging of colorectal cancer.
- Trial name
- SENSE (NCT02167087)
- Testing
- Sentinel node mapping
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Ismail Gögenür
Sarcopenia
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Young Adults
This study will evaluate the adaptations in skeletal muscle that occur in response to 10 weeks of weight training with or without peanut protein supplementation in untrained men and women ages 18-30
- Trial name
- NCT04707963
- Testing
- Peanut protein powder, Full body resistance training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Auburn University
Tubular Adenoma, Colon Cancer
Prospective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based Setting
The purpose of this study is to determine if screening colonoscopy performed on adults with the water exchange method, as opposed to the air method, will have a higher adenoma detection rate.
- Conditions
- Tubular Adenoma, Colon Cancer, Hyperplastic Polyp
- Trial name
- NCT01729416
- Testing
- Water Exchange Colonoscopy, Air Colonoscopy
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of California, Davis
Psychomotor Impairment
Combined Alcohol and Cannabis Effects on Skills of Young Drivers
Alcohol and cannabis are the two most widely used substances of abuse in the world and are the psychoactive substances most often found in seriously and fatally injured drivers.
- Trial name
- NCT03106363
- Testing
- alcohol, delta 9 tetrahydrocannabinol
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Application Site Discomfort
The Effect of Intraoral Spray Application on Thirst and Thirst Comfort in Patients Undergoing Gynecological Surgery
It is important for healthcare professionals to provide care for gynecologic surgery patients using current evidence-based approaches.
- Trial name
- NCT06108687
- Testing
- water spray application
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Gaziantep Islam Science and Technology University
Pulpitis, Caries; Dentin
The Effect of Cryotherapy on the Outcome of Pulpotomy and Root Canal Treatment
The goal of this randomized clinical trial is to compare the outcome of total amputation and root canal treatment with or without cryotherapy in terms of postoperative pain, quality of life, and treatment success for the…
- Conditions
- Pulpitis, Caries; Dentin, Pain, Postoperative
- Trial name
- NCT06183021
- Testing
- Vital pulp cryotherapy, Intracanal cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Ondokuz Mayıs University
Gynecological Laparoscopy
Pain Relief by Intra-Peritoneal Nebulization of Ropivacaine Under Remifentanil Anesthesia for Gynecological Laparoscopy
In our prospective, randomized, placebo controlled and double-blinded study we will study the efficacy of intraperitoneal ropivacaine nebulization on pain relief during gynecologic laparoscopic surgery.
- Trial name
- PSDR (NCT00927979)
- Testing
- 10 mLRopivacaine 1%, Water for injection, 10 mL Ropivacaine 1%
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Meconium Aspiration Syndrome, Persistent Pulmonary Hypertension of Newborn
Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns
The purpose of this study is to to study the role of oral Sildenafil in Persistent Pulmonary Hypertension of Newborn (PPHN) secondary to Meconium Aspiration Syndrome (MAS) in newborns and to study risk factors of MAS developing…
- Trial name
- OSiNPH (NCT01757782)
- Testing
- Oral Sildenafil
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Sir Takhtasinhji General Hospital
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