Clinical trials: Water
Analgesic Response
Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals
The aim of this study is to examine the effects of opioid analgesics on acute pain in participants maintained on buprenorphine+naloxone (Suboxone) for opioid use disorders.
- Trial name
- NCT02136784
- Testing
- morphine sulfate, hydrocodone, hydromorphone HCI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Los Angeles
Erectile Dysfunction
A Relative Bioavailability Study Between Two Formulations Of Sildenafil Citrate
The purpose of this study is to perform a relative bioavailability study between two formulations of sildenafil citrate.
- Trial name
- A1481272 (NCT00904748)
- Testing
- sildenafil citrate 100 mg CT, Viagra®
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Maxillary Transverse Deficiency (MTD)
Effectiveness of Aligners Versus Rapid Maxillary Expansion
Aim of the study is to assess the effectiveness of Invisalign® First clear aligners compared to tooth-borne Hyrax-type maxillary expander on palatal morphology in growing subjects using 3D technology.
- Trial name
- NCT04760535
- Testing
- Invisalign® First Phase I treatment (Align Technology, Inc., Santa Clara, CA, USA), Tooth-borne Hyrax-type maxillary expander
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Turin, Italy
Diabetes, Hypertension
FFA Hypertension and Inflammation in Lean and Obese Subjects
Although a large number of obese patients develop high blood pressure, the cause is unknown. The purpose of this study is to look at the effect of high fatty acids (a type of fat) in the development of high blood pressure in…
- Conditions
- Diabetes, Hypertension, Obesity
- Trial name
- FFAADA (NCT00721617)
- Testing
- Intralipid 20%, Normal Saline, Oral fat load
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Metastatic Prostate Cancer
68Ga-PSMA PET/CT for Ra223 Assessment
Primary objective: i.The primary objective is to compare the diagnostic positivity in progression of 68Ga-PSMA PET and Bone scan.
- Trial name
- NCT04951817
- Testing
- Ga-68 PSMA ligand
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- Chang Gung Memorial Hospital
Pharmacokinetics
Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers
The primary objective was to compare the rate and extent of absorption of Metformin XR after administration of a Test Product Metformin 1000 mg Prolonged Release Tablets (JSC Farmak, Ukraine) and Reference Product Glucophage® XR…
- Trial name
- NCT05123781
- Testing
- Metformin 1000 mg Prolonged Release Tablets (JSC Farmak, Ukraine), Glucophage® XR 1000 mg Prolonged Release Tablets (Merck Serono Ltd, UK)
- Where
- Czechia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Joint Stock Company "Farmak"
Healthy
Pilot Study on the Effect of a XOS95 on the Human Gut Microbiome
The purpose of this clinical trial is to assess the efficacy of a novel prebiotic, XOS95, at two different dosages, in comparison to a placebo by assessing shifts in microbial populations after 8 weeks of supplementation…
- Trial name
- NCT03074019
- Testing
- Xylooligosaccacharide, Maltodextrin
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Prenexus Health
Ulcerative Colitis
Effect of Aloe Vera in the Inflammation of Patients With Mild Ulcerative Colitis
The Ulcerative Colitis (UC) belongs to the group of diseases called Inflammatory Bowel Disease (IBD) which is characterized by a chronic ulceration of the colon.
- Trial name
- AVIUC (NCT01783119)
- Testing
- Aloe Barbadensis Miller
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Venous Leg Ulcer, Diabetic Foot Ulcer
A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lower Leg Ulcers
This study will be a multicenter, prospective, open label, one-arm study intended to assess the clinical performance and safety of EX-02 in debridement of lower leg ulcers: Venous Leg Ulcers (VLU) and Diabetic Foot Ulcer (DFU).
- Trial name
- NCT04817228
- Testing
- EscharEx (EX-02 formulation)
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- MediWound Ltd
Squamous Cell Carcinoma of Head and Neck, Chemotherapy Induced Nausea and Vomiting
A Standardized Intervention to Improve the Management of Chemotherapy-induced Nausea and Vomiting
The goal of this clinical trial is to investigate the effect of a nurse-led standardized intervention on chemotherapy induced nausea and vomiting (CINV) in patients with head and neck squamous cell carcinoma.
- Trial name
- NCT05792228
- Testing
- nurse-led standardized intervention
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Laparoscopic Hysterectomy and/or Laparoscopic Sacrocolpopexy
Mechanical Bowel Preparation Before Laparoscopic Hysterectomy and Laparoscopic Sacrocolpopexy: a Randomized Controlled Trial
The purpose of this study is to learn about bowel preparation (cleansing) before laparoscopic hysterectomy and/or sacrocolpopexy.
- Trial name
- NCT01576965
- Testing
- Fleet Enema (sodium biphosphate and sodium phosphate)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
TENS and Spasticity in Stroke Patients
study aims to evaluate the efficacy of high and low frequency TENS on spasticity, strength and functional status in stroke patients.
- Trial name
- NCT05075109
- Testing
- High Frequency TENS, Low Frequency TENS, Task Related Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Tolerance, Pharmacokinetic
F573 Ia Clinical Trial
Tolerance and PK study of F573
- Trial name
- NCT04820049
- Testing
- F573
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Continent Pharmaceutical Co, Ltd.
COVID-19, Children, Only
Water and Land-based Exercise for Children With Post COVID-19 Condition
The latest data indicate that post COVID-19 condition is frequent in children and adolescents, with the most common symptoms being fatigue, shortness of breath, exercise intolerance and weakness.
- Conditions
- COVID-19, Children, Only, Lung Function Decreased, Quality of Life
- Trial name
- postcovidkids (NCT05216549)
- Testing
- Water-based exercise, Land-based exercise
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Józef Piłsudski University of Physical Education
Exercise, Hydration
Betaine Addition to Water Loading Prior to Running Exercise
This randomized, double-blind, placebo-controlled crossover study will investigate whether acute betaine ingestion as part of a pre-exercise hyperhydration strategy improves endurance running performance and influences…
- Trial name
- NCT07840248
- Testing
- Anhydrous Betaine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Cardiovascular Health
Evaluate Efficacy of Oxyjun on Cardiovascular Health in Healthy Individuals.
Terminalia arjuna, commonly known as arjuna, that belongs to the family of Combretaceae. Most clinical and experimental studies for Terminalia arjuna, have suggested that the crude drug possesses anti-ischemic, antioxidant…
- Trial name
- NCT04715126
- Testing
- Oxyjun
- Where
- 4 sites in India
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Healthy Nutrition
Studying Glucose and Appetite Response With Alternatives to Soda Pop
The primary aim of this clinical trial is to determine the acute effects of OLIPOP (a lower sugar, high fiber prebiotic soda) consumption, compared to consumption of a commercially available sugar-sweetened soda pop, on blood…
- Trial name
- SODA-SWAP (NCT06427915)
- Testing
- OLIPOP prebiotic soda, Traditional sugar-sweetened cola
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Olipop, PBC
Post Endodontic Pain
Effect of DCS on Post-Endodontic Pain
The aim of this randomized, triple-blind, parallel-group clinical trial was to evaluate the effects of calcium hydroxide (CH), diclofenac sodium (DCS), and their combination (CH+DCS) as intracanal medicaments on post-endodontic…
- Trial name
- NCT06632015
- Testing
- Calcium Hydroxide (CH), Diclofenac Sodium (DCS), Calcium Hydroxide + Diclofenac Sodium (CH + DCS)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Mustafa Kemal University
Cryotherapy Effect
Cryoprotection of Chemotherapy-induced Oral Mucositis After Autologous Stem Cell Transplantation, a Randomized Study
This study evaluates, among study patients with lymphoma or myeloma undergoing autologous SCT, whether cooling oral mucosa with a cooling device compared with ice cubes/crushed ice or ice pop succeeds in reducing the degree of…
- Trial name
- NCT03203733
- Testing
- Cooral™, cryotherapy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 182 people
- Sponsor
- Uppsala University
Overweight
Time to Eat Study - Pilot
The goals of this pilot study is to evaluate the safety and feasibility of time restricted feeding in an older adult population.
- Trial name
- NCT03590847
- Testing
- Intermittent Fasting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
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