Clinical trials: Water
RECTAL NEOPLASMS
Transanal Endoscopic Microsurgery Versus Endoscopic Submucosal Dissection For Large Rectal Adenomas
Objective: Recent non-randomized studies suggest that extended endoscopic submucosal dissection (ESD) is equally effective in removing large rectal adenomas as transanal endoscopic microsurgery (TEM).
- Trial name
- TEMENDO (NCT01023984)
- Testing
- TEM - Transanal Endoscopic Microsurgery, ESD - Endoscopic Submucosal Dissection
- Where
- Italy
- Sponsor
- European Association for Endoscopic Surgery
Dental Plaque
Efficacy of Plaque Removal of a Novel Brushing Device
The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.
- Trial name
- NCT05038293
- Testing
- Automated mouthpiece-based toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Familial Hypercholesterolemia - Homozygous
Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia
This was a pivotal phase III study designed to evaluate safety, tolerability, and efficacy of inclisiran in adolescents with homozygous familial hypercholesterolemia (HoFH) and elevated low density lipoprotein cholesterol (LDL-C).
- Trial name
- ORION-13 (NCT04659863)
- Testing
- Inclisiran
- Where
- 11 sites in United States, Canada and 6 more
- Volunteers
- 13 people
- Sponsor
- Novartis Pharmaceuticals
Gastrointestinal Injury, Acute Mountain Sickness
Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude
The aim of this randomized, crossover clinical trial is to determine the efficacy of a gut microbiota-targeted nutritional intervention containing a blend of fermentable fibers and polyphenols (FP) for mitigating increases in GI…
- Trial name
- NCT04111263
- Testing
- FP, High altitude, Sea level
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Constipation - Functional
Effectiveness and Safety of Benemix® in Constipation
The goal of this clinical trial is to find out whether the functional food Benemix® helps treat constipation in adults and whether it is safe to use.
- Trial name
- (Benemix-UdeA) (NCT07427914)
- Testing
- Benemix®, a functional food composed of turmeric, onion, magnesium, and lactose-free, skimmed milk powder
- Volunteers
- 80 people
- Sponsor
- Universidad de Antioquia
Exercise Performance
Effects of Beetroot Juice and Caffeinated Coffee on Exercise Performance in Recreationally Active Men
The goal of this clinical trial was to evaluate how acute intake of beetroot juice, caffeinated coffee, and their combination affected aerobic and anaerobic exercise performance in healthy recreationally active men.
- Trial name
- NCT07797062
- Testing
- Beetroot juice, Caffeinated Turkish Coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Constipation, Intestinal Functional Disorder
The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement
The objective of this study is to evaluate whether the TCI604 probiotics has the potential to enhance human gut function and alleviate constipation.
- Trial name
- NCT07135362
- Testing
- TCI604 probiotics
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Rotator Cuff Tears
Hydrotherapy Versus Classical Rehabilitation After Surgical Rotator Cuff Repair
Postoperative rehabilitation following rotator cuff repair is important to promote tendon healing, restore strength, and recover normal function.
- Trial name
- NCT05106842
- Testing
- Hydrotherapy, Land-based Therapy
- Where
- Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- La Tour Hospital
Fractures, Sprain
Epidemiology of Incidents and Accidents in Sport. Influence of Moisture.
sports accidents and incidents are relatively frequent. We hypothesize that the pursuit of good hydration, including days without training or competition could prevent their occurrence
- Conditions
- Fractures, Sprain, Stress Fractures, Aches
- Trial name
- NCT02346786
- Testing
- eau minérale d'Aix-Les-Bains, tap water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Rhumatologique et Thermal
Fluoridation
Oral Fluoride Bioavailability by the Consumption of Meals Prepared With Fluoridated Water or Salt
This study will assess the concentration of fluoride in saliva and dental biofilm (fluid and solids) during and up to 2 hours after the consumption of typical Brazilian meals prepared with fluoridated water (0.7 ppm F) or…
- Trial name
- NCT02776280
- Testing
- Meal
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Growth Problem, Low Weight
Evaluating the Effect of Nutritional Supplementation on Growth of Short and Lean Adolescents Boys
Study design: Double blind, randomized, placebo controlled study. Participants will be randomly assigned either to the intervention group or the placebo control group.
- Conditions
- Growth Problem, Low Weight, Short Stature
- Trial name
- NCT02389803
- Testing
- Nutritional supplementation standardized formula
- Where
- 3 sites in Israel
- Volunteers
- 160 people
- Sponsor
- Rabin Medical Center
Healthy
Bioequivalence Study For Orally-Disintegrating Tablet Of Sildenafil
The purpose of this study is to assess the bioequivalence of Sildenafil ODT 50 mg without water to Japanese commercial oral tablet of sildenafil citrate (Viagra® tablet) 50 mg under fasted conditions.
- Trial name
- NCT01737203
- Testing
- Viagra, sildenafil ODT
- Where
- Japan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hepatopancreaticobiliary (HPB) Malignancy, Surgery
The HepatoPancreaticoBiliary Resection Arginine Immunomodulation (PRIMe) Trial
This is a randomized controlled blinded superiority trial to evaluate the impact of perioperative immunosupplementation on immune function following resection for hepatopancreaticobiliary (HPB) malignancy.
- Trial name
- PRIMe (NCT04549662)
- Testing
- Active A, Active B, Lipid bolus
- Where
- 2 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Sunnybrook Health Sciences Centre
Healthy Volunteers
Crossover Study to Evaluate the Relative Bioavailability and Palatability of a Lenvatinib Suspension Compared to the Capsule Formulation in Adult Healthy Volunteers
The study will be conducted in adult healthy participants and will consist of two phases: Prerandomization and Randomization. The Prerandomization Phase will consist of 2 periods: a Screening Period and a Baseline Period.
- Trial name
- NCT02792829
- Testing
- Lenvatinib
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Liver Disease
A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices
Compare VBL and cyanoacrylate injection (CI) in the treatment of EV in patients with advanced liver disease regarding eradication, bleeding, mortality, complication and recurrence rates.
- Trial name
- NCT00799851
- Testing
- Variceal band ligation, cyanoacrylate injection
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of São Paulo
Congenital Fibrinogen Deficiency, Afibrinogenemia
Pharmacokinetic, Efficacy, and Safety Study of Octafibrin Compared to Haemocomplettan/Riastap
The purpose of this study is to investigate pharmacokinetic properties, surrogate efficacy and safety of Octafibrin compared to Haemocomplettan® P/RiaSTAPTM in patients with congenital fibrinogen deficiency
- Trial name
- NCT01575756
- Testing
- Octafibrin, Haemocomplettan® P or RiaSTAPTM
- Where
- 10 sites in United States, Bulgaria and 4 more
- Volunteers
- 22 people
- Sponsor
- Octapharma
Aging, Protein Metabolism
Metabolite Changes Following Consumption Of Different Protein Drinks In Singapore Older Adults
The study aims to investigate the acute effects of different protein sources (i.e., casein, whey, soy) on metabolomic profiles (e.g., amino acids in the blood), along with other outcomes such as cognitive function, mood, and…
- Trial name
- NCT06956131
- Testing
- Casein Protein Isolate Drink, Whey Protein Isolate Drink, Soy Protein Isolate Drink
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Mycosis
Sautour PHRC IR 2008
Fusarium are microscopic filamentous fungi that live as saprobiontics in outside environments. They are found in the soil, the air, in water and on numerous plants.
- Trial name
- SautourPHRCI08 (NCT02859831)
- Testing
- water samples
- Where
- France
- Volunteers
- 551 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pregabalin, Optic Nerve Sheath Diameter Measurement
Effect of Pregabalin on Optic Nerve Sheath Diameter in Craniotomy Patients.
When patients undergo brain tumor removal surgery (craniotomy), the pressure inside the skull may increase, which can lead to brain swelling and slower recovery.
- Conditions
- Pregabalin, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Changes
- Trial name
- NCT07630753
- Testing
- Pregabalin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Microbial Colonization
Probiotics and Intestinal Microbiome in Preterm Infants
The gut microbiome plays a significant role in balancing the inflammatory system in the immature gut. A breakdown in this balance with altered colonization of the microbiota in very low birth weight (VLBW) preterm infants is…
- Trial name
- NCT03422562
- Testing
- Florababy
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Belal Alshaikh
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