Clinical trials: Water, completed
Peroxisome Biogenesis Disorders
Betaine and Peroxisome Biogenesis Disorders
The PBD are a rare group of inherited disorders due to the failure to form functional cellular peroxisomes. Most patients have progressive hearing and visual loss, leading to deafness and blindness, as well as neurological…
- Trial name
- NCT01838941
- Testing
- Betaine
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Gastric Emptying
Gastric Emptying After Bread Consumption
The rate of gastric emptying is proposed to be one of the major determinants of postprandial glycemia. A slower gastric emptying will thus result in a less pronounced rise in blood glucose, which is especially desirable in…
- Trial name
- NCT04571866
- Testing
- Beta-glucan bread
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Skeletal Muscle, Extracellular Matrix
Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men
The purpose of this study is to assess which amino acids are affecting acute muscle collagen synthesis in response to supplementation and exercise.
- Conditions
- Skeletal Muscle, Extracellular Matrix, Amino Acids Metabolism, Exercise
- Trial name
- PECS (NCT04596553)
- Testing
- Essential Amino Acid, Collagen Peptide
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1815368 in the Blood
The main objective of this trial is to investigate the effect on the exposure of BI 1815368 in plasma when given as oral single dose together with multiple oral doses of itraconazole (Test, T) as compared to when given alone as…
- Trial name
- NCT05965583
- Testing
- BI 1815368, Itraconazole
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hypercholesterolemia
Study on the Effect of the Intake of a Calcium-bicarbonate Water on Cholesterol Levels
The goal of this study is to evaluate the hypolipidemic effect (reduction of Low Density Lipoprotein Cholesterol "LDL-C" values) of calcium-bicarbonate mineral water "Lete" (alkaline water, high in bicarbonate and calcium ions…
- Trial name
- NCT07026266
- Testing
- Water
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Società Generale delle Acque Minerali S.p.A.
Dental Caries in Children
Toothbrushing Program in Saudi Arabia "TOPS"
Project summary Introduction: Dental caries is a major oral health problem worldwide and is a particular public health challenge in Saudi Arabia. Dental caries cause pain, infection, and negatively impact quality of life.
- Trial name
- NCT05512156
- Testing
- Supervised Toothbrushing
- Where
- Saudi Arabia
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Obesity, Diabetes
Modeling the Epidemiologic Transition Study
This project examines whether individuals' amount of activity energy expenditure (AEE) is related to adiposity and adiposity/diabetes-related hormones in a diverse sample of 2500, and to test the ecological hypothesis that a…
- Trial name
- METS (NCT02925156)
- Where
- United States
- Volunteers
- 2,506 people, healthy volunteers welcome
- Sponsor
- Loyola University
Obstructive Sleep Apnea, Sleep-Disordered Breathing
A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
This is a short term open, randomized cross over trial to explore and compare the efficacy of pharmacological carbonic anhydrase (CA) inhibition on obstructive sleep apnea (OSA) related hypertension.
- Conditions
- Obstructive Sleep Apnea, Sleep-Disordered Breathing, Blood Pressure, Hypertension
- Trial name
- NCT02220803
- Testing
- Acetazolamide, nasal Continuous Positive Airway Pressure (nCPAP)
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Göteborg University
Xerostomia
Consumer Perception of an Experimental Mouthwash After a Single Use in Dry Mouth Subjects
The purpose of this study is to investigate the consumer perception of an experimental mouthwash formulation in population with dry mouth
- Trial name
- NCT03005041
- Testing
- Biotene mouthwash, Bottled mineral water
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes, Gestational
Acute Effects of an Aquatic Physical Exercise on Glycemic Control of Gestational Diabetes
Gestational diabetes mellitus (GDM) is increasing worldwide and has been associated with adverse perinatal outcomes and high risk for chronic disease both for the mother and for the child.
- Trial name
- NCT02931656
- Testing
- Aquatic exercise
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Peripheral Arterial Disease
Home-based Leg Heat Therapy
The objective of this study is to evaluate the benefits of participating for 8 weeks in a home-based daily treatment with heat therapy (HT) or a thermoneutral control intervention, as assessed by vascular function, walking…
- Trial name
- HHT (NCT03763331)
- Testing
- Heat Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Indiana University
Colorectal Cancer, Ovarian Cancer
A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies
This is a two-part Phase 1/2 dose escalation and dose expansion study of an Adenovirus Vector (Ad5/3-D24-GMCSF), Expressing GM-CSF (GM-CSF-encoding adenovirus), ONCOS-102, in combination with anti-programmed death ligand-1…
- Conditions
- Colorectal Cancer, Ovarian Cancer, Appendiceal Cancer
- Trial name
- NCT02963831
- Testing
- ONCOS-102, Durvalumab, Cyclophosphamide
- Where
- 6 sites in United States
- Volunteers
- 67 people
- Sponsor
- Ludwig Institute for Cancer Research
Hypovolemia
Plasma-Lyte 148® versUs Saline Study
The aim of PLUS is to conduct a multi-centre, blinded, randomised, controlled trial (RCT) to determine whether fluid resuscitation and therapy with a "balanced" crystalloid solution (Plasma-Lyte 148®) decreases 90-day mortality…
- Trial name
- PLUS (NCT02721654)
- Testing
- Plasma-Lyte 148®, 0.9% sodium chloride
- Where
- 51 sites in Australia, New Zealand
- Volunteers
- 5,037 people
- Sponsor
- The George Institute
Cardiovascular Risk, Hypercholerolemia
Study of the Effects of Yerba Mate on Cardiometabolic Health
The goal of this clinical trial is to learn if consuming a beverage prepared with yerba mate leaves helps to improve blood lipid levels in persons at high cardiovascular risk.
- Trial name
- INFU-SALUD (NCT06729905)
- Testing
- Yerba mate tea, Control drink
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Healthy Adult Female Participants, Health Behavior
The Effect of Water Conservation Education on Women's Water Use Behaviours
This research will be conducted to evaluate the effects of the Health Belief Model based water saving training prepared for women on the size of the water footprint, water consumption habits and water consumption amount.
- Conditions
- Healthy Adult Female Participants, Health Behavior, Climate Change, Water Use
- Trial name
- NCT06824246
- Testing
- Water conservation education, Monitoring water bill
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Atrial Fibrillation
ReVeRA-201: Etripamil in Atrial Fibrillation, Phase 2
Many patients with atrial fibrillation (AF) experience persistent tachycardia with episodes of rapid ventricular rate despite chronic treatment to reduce ventricular rate.
- Trial name
- NCT04467905
- Testing
- Etripamil
- Where
- 18 sites in Canada, Netherlands
- Volunteers
- 69 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Short Bowel Syndrome
rHGH and Intestinal Permeability in Intestinal Failure
Patients who are being asked to participate in this study have a short small bowel and will be prescribed to take the medication: Zorbtive® ("Zorbtive/Somatropin/(rHGH)").
- Trial name
- rHGH (NCT01380366)
- Testing
- Somatropin, Seven Day Food Diary, Blood Tests (standard of care)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwestern University
Healthy, Frailty
Geriatric Anorexia Study 2.0
Reduction in appetite and/or food intake among older individuals is referred to as anorexia of aging (AOA, also known as Geriatric Anorexia).
- Trial name
- GAS2 (NCT05211973)
- Testing
- Wrist Actigraphy Device, Smart Body Weight Scale, Chair Scale
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Boston University
Autonomic Nervous System Imbalance
Caffeine and the Autonomic Nervous System
Caffeine consumption has been linked to dysfunction of the autonomic nervous system. In this study the investigators analyze the effects of caffeine containing drinks (including energy drinks and coffee) on ECG based parameters…
- Trial name
- NCT04886869
- Testing
- caffeine
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Type 2 Diabetes
Computer Based Intervention for Type 2 Diabetes in Youth
Interactive multimedia programs have been demonstrated to produce substantial change in children's dietary behaviors. This SBIR-Phase 2 protocol will evaluate the two video game interventions designed to change diabetes related…
- Trial name
- NCT00570466
- Testing
- Video Games, Web and DVD knowledge
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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