Clinical trials: Water, completed
Burn Injury
Exercise in Burn Survivors: Cooling Modalities
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT04512976
- Testing
- Control (no cooling modalities), Water Spray Only, Fan Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
COVID-19
Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults
This Phase 1 clinical trial will evaluate the safety, reactogenicity, and immunogenicity of PepGNP-COVID19, a synthetic nanoparticle-based, T cell-priming peptide vaccine against SARS-CoV-2, when administered as a booster dose in…
- Trial name
- NCT07183709
- Testing
- PepGNP-COVID19, Sterile Water for Injection
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Subjects, Schizophrenia
Studies of Frontal Lobe Brain Functioning in Schizophrenia
The purpose of this study is to use brain imaging technology to investigate the role of the frontal lobe of the brain in the thinking of individuals with schizophrenia and other neuropsychiatric disorders and healthy volunteers.
- Conditions
- Healthy Subjects, Schizophrenia, Parkinson Disease
- Trial name
- NCT00001258
- Testing
- Oxygen-15 Water
- Where
- United States
- Volunteers
- 1,039 people
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia, Parkinson's Disease
PET Scanning in Parkinson s Disease
This is an in vivo positron emission tomography (PET) study of regional cerebral dopamine and blood flow in normal volunteers, persons with Parkinson s disease (both familial and sporadic), and those with schizophrenia spectrum…
- Trial name
- NCT00024622
- Testing
- O-15 Water, 18F-Fluoro-L-dopa
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- National Institute of Mental Health (NIMH)
Coronary Artery Disease
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
This a Phase 3, prospective, open-label, multicenter study of [15-O]-H2O injection for PET imaging of subjects with suspected CAD.
- Trial name
- NCT05134012
- Testing
- [O-15]-Water PET Myocardial Perfusion Imaging (MPI)
- Where
- 13 sites in United States, Canada and 4 more
- Volunteers
- 232 people
- Sponsor
- MedTrace Pharma A/S
Hiatal Hernia, Gastroesophageal Reflux Disease
Intrathoracic Sleeve Migration (Sliding Hiatal Hernia) One Year or More After Laparoscopic Sleeve Gastrectomy
Sleeve gastrectomy is the most commonly performed metabolic bariatric operation. After the operation, the upper part of the gastric sleeve can slide up through the opening in the diaphragm into the chest.
- Conditions
- Hiatal Hernia, Gastroesophageal Reflux Disease, Obesity, Postoperative Complications
- Trial name
- NCT07902895
- Testing
- Laparoscopic sleeve gastrectomy, CT of the thorax and abdomen with oral water-soluble contrast
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Kasr El Aini Hospital
Postnatal Adaptation and Stress in Healthy Newborns Born by Cesarean Section
Effect of Amniotic Fluid Odor on Newborn Adaptation and Stress (AFO-NAS)
This study aims to determine whether exposure to the odor of a newborn's own amniotic fluid affects postnatal adaptation and stress in healthy newborns born by cesarean section.
- Trial name
- AFO-NAS (NCT07736235)
- Testing
- Amniotic Fluid Odor Sterile Distilled Water Odor
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Thirst
Effectiveness of Enzyme Spray Intervention on Thirst Relief in Patients With Endotracheal Intubation.
Thirst is a common and distressing symptom among intensive care unit (ICU) patients with endotracheal intubation. Endotracheal intubation, nil per os (NPO) status, oxygen therapy, and medication effects may contribute to oral…
- Trial name
- NCT07533552
- Testing
- Enzyme-based oral spray (Oral7®), Distilled water oral spray
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Yeh,Shiao Feng
Sore Throat, Dysphagia
Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms
This study aims to evaluate the effects of chewing gum and gargling with cold water on common post-bronchoscopy symptoms, such as sore throat and difficulty swallowing (dysphagia).
- Conditions
- Sore Throat, Dysphagia, Patient Satisfaction, Bronchoscopy
- Trial name
- NCT07517926
- Testing
- Chewing Gum, Cold Water Gargle
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Sleep Quality
Effects of Different Footbath Immersion Depths on Sleep Quality Among Older Adults in Long-Term Care Facilities
Sleep disturbances are common among older adults residing in long-term care facilities. Warm-water footbaths may help improve sleep quality; however, different immersion depths may affect the body's response to warming.
- Trial name
- NCT07892560
- Testing
- Ankle-Level Warm-Water Footbath, Below-Knee Warm-Water Footbath
- Where
- 6 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- Cai-Syuan Jiang
Surgery, Nurse's Role
Effects of Aromatic Solution Applied After Surgery
Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required.
- Conditions
- Surgery, Nurse's Role, Throat, Sore, Thirst
- Trial name
- NCT05522023
- Testing
- group treated with aromatic solution, group treated with drinking water
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Healthy Volunteers, Muscle Strength
Acute Effects of Stretching, Kinesio Taping, Cold Water Immersion and Foam Rolling on Wrist Strength and Precise Force and Position Control
Static stretching, dynamic stretching, elastic (Kinesio) taping, brief cold water immersion and foam rolling are used daily in sport and rehabilitation to prepare the forearm and hand, but it is not known whether, immediately…
- Conditions
- Healthy Volunteers, Muscle Strength, Motor Control
- Trial name
- NCT07886736
- Testing
- Static stretching, Assisted dynamic stretching, Kinesio taping
- Where
- Croatia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Grgur Kovačić
Insulin Resistance, Hyperinsulinemia
Graded Insulin Suppression Test P&F
The goal of this study is to learn about how the hormone insulin controls blood sugar in a variety of people. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar…
- Conditions
- Insulin Resistance, Hyperinsulinemia, Obesity, Healthy
- Trial name
- GIST (NCT06592261)
- Testing
- Insulin regular, 2.0-3.2 mU/m2/min (euinsulinemia), Insulin regular, 32 mU/m2/min (hyperinsulinemia), Octreotide Acetate, 6-45 ng/kg/min
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Columbia University
Adiposity, Insulin Sensitivity
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old. The main purpose of the study is to evaluate if stevia has benefits for weight control and metabolic function relative to caloric sweeteners…
- Conditions
- Adiposity, Insulin Sensitivity, Weight Gain, Blood Pressure
- Trial name
- NCT05992688
- Testing
- Sucrose sweetened beverage, Stevia sweetened beverages, Calorie free flavored water beverage
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Pregnancy, Gestational Diabetes Mellitus (GDM)
Gastric Ultrasound After Clear Fluid Intake in Diabetic and Non-Diabetic Pregnant Women
Pulmonary aspiration of gastric contents during anesthesia is a serious perioperative complication associated with significant morbidity and mortality.
- Trial name
- NCT07482098
- Testing
- Oral water intake
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ankara City Hospital Bilkent
Healthy
Study of the Impact of Gastric Interoceptive Signals on the Body Schema Via the Water Load Test II ( GIBS)
The aim of this study was to evaluate whether gastric interoceptive information has a direct impact on the motor and tactile dimensions of the body schema.
- Trial name
- GIBS (NCT07633652)
- Testing
- SKIN test, MOVE, water load test II
- Where
- France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Cold Water Immersion, Immune Function
Cold Water Exposure and Immune Function Study
The purpose of this clinical trial is to explore the effects of a 4 week cold-water immersion (CWI) intervention on measures of immune function, sleep quality, mental health and well-being, and muscular strength.
- Conditions
- Cold Water Immersion, Immune Function, Muscular Strength, Mental Health
- Trial name
- NCT06667479
- Testing
- Cold Water Immersion (CWI) - Cold Tub Immersion (CI), Cold Water Immersion (CWI) - Cold Shower (CS), Control Group (CO)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Obesity
Water Deprivation Protocol
Background: One area in which obese and lean individuals may be different is how their bodies handle water balance and thirst. Studies done in animals suggest that individuals with greater body fat may tolerate periods without…
- Trial name
- NCT01224704
- Testing
- Hypertonic saline infusion, Water deprivation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hyperinsulinemia, Insulin Resistance
Glycemic Effect of Diazoxide in NAFLD
The goal of this clinical trial is to compare a two-week course of diazoxide (at two different doses) and placebo in people with overweight/obesity and insulin resistance (IR) with, or at high risk for, non-alcoholic fatty liver…
- Conditions
- Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State
- Trial name
- NCT05729282
- Testing
- Diazoxide oral suspension, 1 mg per kg per dose, Diazoxide oral suspension, 2 mg per kg per dose, FreeStyle Libre Pro
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Columbia University
Cold Exposure
Cold Water Exposure's Effects on Physical and Mental Health
An interest in cold-water immersion (CWI) to elicit diverse physiological effects has been prevalent for centuries. CWI typically consists of bodily exposure to water at temperatures ranging from 5-10º C for various durations.
- Trial name
- NCT06667193
- Testing
- Cold Water Immersion (CWI) - Cold Tub Immersion (CI), Cold Water Immersion (CWI) - Cold Shower (CS)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado