Clinical trials: conventional surgery, completed
Esophageal Cancer
Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00470184
- Testing
- capecitabine, oxaliplatin, gene expression analysis
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Roswell Park Cancer Institute
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Thyroid Diseases, Goiter
Thyroidectomy-specific Enhanced Recovery After Surgery (ERAS) Protocol
Thyroidectomy is generally considered a low-to-moderate risk operation; however, postoperative pain, nausea/vomiting, and prolonged hospital stays remain common issues.
- Conditions
- Thyroid Diseases, Goiter, Thyroid Neoplasms
- Trial name
- NCT07575243
- Testing
- Enhanced Recovery After Surgery protocol, Conventional perioperative care
- Where
- Egypt
- Volunteers
- 143 people
- Sponsor
- Assiut University
Spinal Metastases, Bone Metastases
Randomized Trial Comparing Conventional Radiotherapy With Stereotactic Radiotherapy in Patients With Bone Metastases - VERTICAL Study
The purpose of the study is to investigate effectiveness of stereotactic body radiotherapy in patients with bone metastatic disease.
- Trial name
- VERTICAL (NCT02364115)
- Testing
- Stereotactic Body Radiotherapy
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- UMC Utrecht
Bone Formation
Piezo-surgery Versus Conventional Drills
Purpose: The aim of this RCT was to evaluate and compare histomorphometric and immunohistochemical characteristics of peri-implant bone tissue after implant site preparation using piezoelectric tips versus conventional drills.
- Trial name
- NCT05753917
- Testing
- Piezo-surgery insert OR Conventional Drills
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- GBR Academy
Colorectal Disorders
Robotic Assisted Colon and Rectal Surgery Prognostic and Outcome Analysis
To analysis surgical outcome between robotic and laparoscopy colon and rectal surgery. Retrospective case-control study of single institute.
- Trial name
- NCT05210647
- Testing
- robotic surgery
- Where
- Taiwan
- Volunteers
- 291 people
- Sponsor
- Taichung Veterans General Hospital
Coronary Artery Bypass Graft Triple Vessel, Blood Coagulation Disorders
Goal-orientated Therapy of Perioperative Disturbance in Hemostasis in Cardiac Surgery
Aim of this study is to investigate whether patients preoperatively treated with acetylsalicylic acid and/or clopidogrel have fewer perioperative bleeding and lower amounts of blood substitution when managed by ROTEM (whole blood…
- Trial name
- NCT00516126
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Basel, Switzerland
Complete Edentulism Due to Periodontal Disease (Disorder)
Post Extraction Wound Healing Evaluation of Immediate Complete Denture Using IPR Scale
In the first part, after a brief introduction, the advantages and disadvantages of immediate dentures are compared. There is a detailed discussion on assessment and treatment planning which includes history taking, examination of…
- Trial name
- NCT05464914
- Testing
- CEO Pack
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Dental Implant
An Invivo Study to Compare the Stability of Dental Implants With or Without Platelet Rich Fibrin Application
The purpose of this study was to evaluate the effects of (Platelet Rich Fibrin) PRF application on implant osseointegration in the early phase of healing.
- Trial name
- NCT02190409
- Testing
- Dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ELİF ONCU
Colorectal Cancer
Capecitabine and Radiation Therapy With or Without Panitumumab in Treating Patients With Advanced Rectal Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00814619
- Testing
- panitumumab, capecitabine, therapeutic conventional surgery
- Where
- 24 sites in Hungary, Switzerland
- Volunteers
- 68 people
- Sponsor
- Swiss Cancer Institute
Pain, Head and Neck Disorder
Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery
Opioid tolerance in the perioperative period is inevitable especially with ultra-short acting agents such as remifentanil. Existing evidence had shown that opioid induced hyperalgesia due to neuroplastic changes in the central as…
- Trial name
- NCT02416752
- Testing
- Remifentanil, choice of intra-operative opioids were left to the discretion of anesthesiologist
- Where
- Singapore
- Volunteers
- 222 people
- Sponsor
- Singapore General Hospital
Visceral and Digestive Surgery
REmote Data Acquisition After SURgery
In this clinical study, the investigators will compare vital parameters measurements obtained using continuous data from reference monitors and continuous wireless MultiSense® monitoring patch in 60 patients immediately after…
- Trial name
- REDASUR (NCT04480385)
- Testing
- Remote Automated Monitoring System
- Where
- France
- Volunteers
- 63 people
- Sponsor
- IHU Strasbourg
Neuroblastoma
Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00017225
- Testing
- filgrastim, carboplatin, cisplatin
- Where
- 94 sites in Germany, Netherlands and 1 more
- Sponsor
- German Society for Pediatric Oncology and Hematology GPOH gGmbH
Pelvic Organ Prolapse
SORD-BILL Vs Conventional Options During Sacral Colpopexy for POP
This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic sacral colpopexy associated to subtotal hysterectomy for the treatment of POP could be further reduced using PKS BILL…
- Trial name
- NCT02479685
- Testing
- PKS BILL-PKS PlasmaSORD Versus Conventional surgical techniques
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Head and Neck Cancer
Bevacizumab, Docetaxel, and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00281840
- Testing
- bevacizumab, docetaxel, conventional surgery
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Case Comprehensive Cancer Center
Complications Due to Coronary Artery Bypass Graft
Effects of Segmental Breathing Exercise in Patients Awaiting Coronary Artery Bypass Graft Surgery (CABG)
To determine the effects of preoperative segmental breathing exercise on postoperative pulmonary complications in patients awaiting coronary artery bypass graft surgery (CABG). This study will be a randomized controlled trial.
- Trial name
- NCT05585138
- Testing
- segmental breathing exercise, deep breathing
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Readmission, Perioperative Care
Reducing Surgical Readmissions Through Mobile Technology
This randomized trial will study the effect of a mobile app that facilitates patient engagement (patients undergoing complex abdominal surgery will track metrics of interest to the surgeon, submit reports on their…
- Trial name
- NCT04540315
- Testing
- MobiMD
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Wisconsin, Madison
Intraoperative Hypotension, Intraoperative Complications
Comparison of Conventional Fluid Management Protocol With Targeted Pleth Variability Index (PVI) Monitoring Protocol During Total Abdominal Hysterectomy and Bilateral Salpingooferectomy Operation
This study aims to compare the volume management methods performed by using conventional method and PVI monitoring in intraoperative fluid treatment during bilateral salpingo-oophorectomy and total hysterectomy operation.
- Conditions
- Intraoperative Hypotension, Intraoperative Complications, Hypervolemia, Acute Renal Failure
- Trial name
- NCT04775576
- Testing
- Pleth Variability Index, Conventional fluid theraphy, Anesthesia method
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Analgesia
Rivanna Ultrasound for Neuraxial Block
We hypothesize that the Rivanna Accuro or similar U/S device would reduce time to success of identifying epidural and/or intrathecal spaces as compared to conventional palpation method.
- Trial name
- NCT03214640
- Testing
- Rivanna Accuro US Device, Palpation, Neuraxial Analgesia
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Wake Forest University Health Sciences
Chronic PJIs
Heraeus MicroDTTect Lyon Pilot Studyprosthetic Joint Infections (PJIs)
Prosthetic joint infections (PJIs) are one of the main causes of implant failure after joint arthroplasty. Identification of the causal organism is crucial for successful treatment.
- Trial name
- NCT04371068
- Testing
- Culture of removed prosthesis using DTT
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon