Clinical trials: conventional surgery, completed
Aortic Stenosis Symptomatic
ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03)
First-In-Man Study on the ACURATE TF™ Transfemoral Aortic Bioprosthesis Implantation in Patients with Severe Aortic Stenosis to collect human feasibility data pertaining to the safety and performance of the device.
- Trial name
- 2011-03 (NCT03752996)
- Testing
- ACURATE TF™ Aortic Valve System
- Where
- 5 sites in Brazil, Germany
- Volunteers
- 140 people
- Sponsor
- Symetis SA
Fast Track, Tranexamic Acid Adverse Reaction
Implementation of a Rapid Recovery Protocol in Total Knee Arthroplasty
Patients undergoing total knee arthroplasty will follow two different rehabilitation protocols. In one of them, they will start walking the day of surgery and discharged on a 48 hours basis.
- Conditions
- Fast Track, Tranexamic Acid Adverse Reaction, Knee Osteoarthritis
- Trial name
- NCT03823573
- Testing
- Walk within 24 hours
- Where
- Spain
- Volunteers
- 175 people
- Sponsor
- Ignacio Aguado Maestro
Complication of Surgical and Medical Care.
Enhanced Recovery After Surgery in Major Intrabdominal Procedures.
Enhanced Recovery After Surgery (ERAS) programs have been introduced with aims of attenuating the stress response to surgery and enabling rapid recovery.
- Trial name
- NCT01400711
- Testing
- ERAS perioperative care, Traditional
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- St. Andrew's General Hospital, Patras, Greece
Esophageal Cancer
Radiation Therapy and Combination Chemotherapy With or Without Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as fluorouracil and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by…
- Trial name
- NCT00416858
- Testing
- cisplatin, fluorouracil, adjuvant therapy
- Volunteers
- 40 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Atrial Fibrillation, Persistent
Comparison Between Extended Cryoablation, Standard Cryoablation, and Radiofrequency Ablation
The objective of this study is to test the efficacy hypothesis that extended cryoballoon ablation is superior to either standard cryoballoon ablation or radiofrequency ablation
- Trial name
- EXCAPE-AF (NCT07034378)
- Testing
- Radiofrequency ablation, Extended cryoballoon ablation, Standard cryoballoon ablation
- Where
- 3 sites in South Korea
- Volunteers
- 288 people
- Sponsor
- Asan Medical Center
Colorectal Cancer
Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as fluorouracil and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or…
- Trial name
- NCT00296608
- Testing
- fluorouracil, leucovorin calcium, conventional surgery
- Volunteers
- 762 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Thyroid Diseases, Goiter
Thyroidectomy-specific Enhanced Recovery After Surgery (ERAS) Protocol
Thyroidectomy is generally considered a low-to-moderate risk operation; however, postoperative pain, nausea/vomiting, and prolonged hospital stays remain common issues.
- Conditions
- Thyroid Diseases, Goiter, Thyroid Neoplasms
- Trial name
- NCT07575243
- Testing
- Enhanced Recovery After Surgery protocol, Conventional perioperative care
- Where
- Egypt
- Volunteers
- 143 people
- Sponsor
- Assiut University
Complication of Ventilation Therapy, Postoperative Respiratory Complications
Intraoperative Protective Ventilation and Postoperative Pulmonary Complications
The purpose of this pilot study is to identify the optimal way to ventilate patients during abdominal surgery in order to reduce the amount of post-operative pulmonary complications in patients at moderate and high-risk for them.
- Trial name
- NCT02671721
- Testing
- Maximal Compliance, Transpulmonary Pressure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Cesarean Section, Gum Chewing
Role of Gum Chewing in Post-operative Gut Motility After Cesarean Section
Many women deliver by caesarean section nowadays. The proportion of women who deliver by caesarean section ranges from 15% to over 50%, in some countries.
- Conditions
- Cesarean Section, Gum Chewing, Gut Motility
- Trial name
- NCT06952985
- Testing
- Sugar free chew gum, Nil Per Oral
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr Maryam Aslam
Glaucoma, Corneal Damage
Corneal Endothelium After Glaucoma Surgery
The purpose of this trial is to study the change in corneal endothelial cell after glaucoma surgery, non-contact specular microscopic examination is performed for the patients who underwent glaucoma surgery; trabeculectomy and…
- Conditions
- Glaucoma, Corneal Damage, Intraocular Pressure
- Trial name
- NCT00863018
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Chungnam National University
Menorrhagia, Pelvic Pain
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic Hysterectomy
Robotic-assisted surgery is becoming more prominent within the specialty of Gynecologic surgery with little direct evidence that it is if not better than traditional laparoscopic surgery, at least equivalent.
- Conditions
- Menorrhagia, Pelvic Pain, Hysterectomy
- Trial name
- NCT02118974
- Testing
- Hysterectomy
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Milton S. Hershey Medical Center
Anesthesia
Lung Recruitment and Postoperative CPAP
General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation.
- Trial name
- LRvsCPAP (NCT02502279)
- Testing
- Engström Datex-Ohmeda ICU Ventilator, Postoperative CPAP mask
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Scheduled Cardiac Surgery, Sternotomy
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters
Postoperative pain after cardiac surgery is a risk factor for postoperative complications. In cardiac surgery, pain is more intense during the first 48 hours and disturbs the patient's capacity of coughing, deep breathing, and…
- Conditions
- Scheduled Cardiac Surgery, Sternotomy, Elderly Patients, Obesity
- Trial name
- BLS-Sterno (NCT01828788)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Total Knee Arthroplasty Guidance Systems Study
In total knee replacement operations, the surgeon uses techniques and instruments to guide the operation and ensure that all parts of the prosthesis (the artificial knee surfaces) are placed into the correct position.
- Trial name
- NCT02830997
- Testing
- Stereotactic guidance system
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ormonde M. Mahoney, MD
Neuroblastoma
Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug, and giving them before surgery, may shrink the tumor so that it can be removed…
- Trial name
- NCT00025623
- Testing
- carboplatin, cyclophosphamide, doxorubicin hydrochloride
- Where
- 11 sites in Austria, Belgium and 9 more
- Sponsor
- European Infant Neuroblastoma Study Group - 1999
Dental Implant
Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation
A closed sinus augmentation is performed for dental implant placement.
- Trial name
- NCT06296459
- Testing
- 3D R100 scanner, Conventional Radiograph
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Tooth Loss
Study Comparing Osseodensification With Standard Drilling
The purpose of this study is to examine how Osseodensification, a well-defined bone preparation procedure utilizing special densifying burs (a tool to prepare bone) compares to the standard drilling procedure utilizing regular…
- Trial name
- OD/SD (NCT04779203)
- Testing
- Osseodensification Densah Bur
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Jackson Implant Surgery
Brain Cancer, Brain Tumors
Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid
The aim of the study "Fluorescence-guided resection of malignant gliomas with 5-Aminolevulinic acid (5-ALA) vs. conventional resection" is to determine how accurately contrast agent-accumulating tumour can be removed by primary…
- Conditions
- Brain Cancer, Brain Tumors, Cancer of Brain, Primary Brain Tumors
- Trial name
- NCT00241670
- Testing
- 5-aminolevulinic acid (5-ALA)
- Volunteers
- 415 people
- Sponsor
- medac GmbH
Colon Cancer
Safety and Efficacy of Single Port Laparoscopic Surgery in Colon Cancer
This randomized trial is designed to identify the safety and efficacy of single port laparoscopic surgery in colon cancer compared with conventional laparoscopic surgery.
- Trial name
- NCT01203969
- Testing
- Single port laparoscopic surgery, Conventional laparoscopic surgery
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Kyunghee University Medical Center
Early Gastric Cancer, Gastric Dysplasia
Conventional Biopsies vs pCLE for Diagnosis of Superficial Gastric Neoplasia
Confocal endomicroscopy (CLE) allows real-time in-vivo high-resolution and high-magnification imaging of the gastrointestinal epithelium, which is comparable to histopathology.
- Trial name
- pCLE (NCT01688687)
- Testing
- Endoscopic submucosal dissection
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Soonchunhyang University Hospital
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