Clinical trials: conventional surgery, completed
Endometrial Neoplasms
Robotic Versus Abdominal Surgery for Endometrial Cancer
This study is intended to explore differences in oncologic and surgical safety between robotic assisted laparoscopy and conventional abdominal surgery for high risk endometrial cancer.
- Trial name
- RASHEC (NCT01847703)
- Testing
- Robotic surgery, Abdominal surgery
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Hirschsprung Disease
Minimally Invasive Surgical Intervention for Hirschsprung's Disease in Pediatric Patients
Hirschsprung's disease (HD) is a congenital disorder characterized by the absence of enteric ganglion cells in the distal bowel, leading to functional obstruction, delayed meconium passage in neonates, and chronic defecation…
- Trial name
- NCT06874686
- Testing
- Minimally invasive laparoscopic pull-through surgery
- Where
- Vietnam
- Volunteers
- 1,050 people
- Sponsor
- National Children's Hospital, Vietnam
Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not known whether combining chemotherapy with bone marrow or peripheral stem cell transplantation is…
- Conditions
- Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Testicular Germ Cell Tumor
- Trial name
- NCT00002596
- Testing
- bleomycin sulfate, filgrastim, carboplatin
- Where
- 153 sites in United States, Australia and 2 more
- Volunteers
- 270 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Cardia Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery
This phase Ib/II trial studies the side effects and best way to give pembrolizumab with combination chemotherapy and radiation therapy before surgery and to see how well it works in treating adult patients with gastroesophageal…
- Conditions
- Gastric Cardia Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Stage IB Gastric Cancer AJCC v7, Stage II Gastric Cancer AJCC v7
- Trial name
- NCT02730546
- Testing
- Carboplatin, Computed Tomography, Fluorouracil
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Mayo Clinic
ST Elevation Myocardial Infarction
Minimal Invasive Procedure for Myocardial Infarction
In the setting of primary Percutaneous Coronary Intervention (PCI), the investigators hypothesize that a 24-48 hour delay strategy of stenting after successful thrombus aspiration and establishment of Thrombolysis In Myocardial…
- Trial name
- MIMI (NCT01360242)
- Testing
- MIMI procedure (two-step strategy), Immediate Stenting (one-step strategy)
- Where
- 24 sites in France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Cardiovascular Diseases
Continuous Hemofiltration During Cardiopulmonary Bypass and Its Effect on Lactatemia
This study aims to analyze the impact of using polysulfone membranes on continuous ultrafiltration with volume replacement in patients undergoing cardiac surgery.
- Trial name
- CPB-LACTATE (NCT03412968)
- Testing
- Polysulfone Filter, Procedure/ Surgery: without Polysulfone Filter
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- University of Cadiz
Burns
Effect of Autologous Fat Grafting on Acute Burn Wound Healing
the study evaluates the role of autologous fat grafting and the usage of nanofat in the treatment of the acute burn injuries in different genders and its influences on the healing time and hospital stay, pain control, the need…
- Trial name
- NCT03791710
- Testing
- autologous fat grafting, Topical Cream, split thickness skin grafting
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmed Mohamed Abouzaid
Cardiovascular Complication
Blood Pressure Management on Cardiovascular AdveRse Events After Major Abdominal Surgery
This study is a multicenter randomized controlled trial comparing an intensive intraoperative blood pressure management strategy versus conventional practice for preventing cardiovascular events in high-risk patients undergoing…
- Trial name
- BP-CARES (NCT04430920)
- Testing
- Intensive intraoperative blood pressure management, Conventional intraoperative blood pressure management
- Where
- 3 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cystocele
RUG-WEAVING PLICATION IN CYSTOCELE TREATMENT
In this study was to compare the 2-year results of the Rug Wave plication technique, which it present as a natural tissue repair technique in cystocele, with the conventional technique in terms of both recurrence and patient…
- Trial name
- NCT07336108
- Testing
- rug weaving-like plication technique, group 2:conventional technique cystocele treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Myopia, Myopic Astigmatism
Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia
The objectives of this study are to evaluate the safety and efficacy of a treatment regimen for high myopia and myopic astigmatism: LASIK followed by crosslinking performed with the KXL Crosslinking-System and VibeX Xtra…
- Conditions
- Myopia, Myopic Astigmatism, Crosslinking, Corneal Ectasia
- Trial name
- NCT03913338
- Testing
- LasikXtra, LASIK
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Comprehensive Complication Index
Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients With Diabetes
The goal of this multi-center, pragmatic, randomized controlled trial is to assess the effectiveness of continuous glucose monitoring (CGM) compared with conventional monitoring in enhancing surgical outcomes for diabetic…
- Trial name
- NCT06331923
- Testing
- Continuous glucose monitoring (CGM) device
- Where
- 8 sites in China
- Volunteers
- 9,877 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Pulmonary Wedge Resection
Small-diameter Closed Thoracic Drainage Tube Fixation Method
Objective: To explore the design feasibility and application effect of triple-buffer-system-fixed small-diameter (18 F) thoracic closed drainage tubes following lung wedge resection.
- Trial name
- NCT05601076
- Testing
- fixed with the triple-buffer system, fixed using the conventional lifting platform method
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University
Accelerate Tooth Movement
The Effect of Corticotomy in En-mass Retraction
To compare patients who will undergo orthodontics treatment involving upper premolar extraction for space of time whether with or without corticotomy by Piezotome.
- Trial name
- NCT03180151
- Testing
- piezotome assisted orthodontic tooth movement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Sarcoma
Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy before surgery may shrink the tumor so that it can be removed.
- Trial name
- NCT00091351
- Testing
- conventional surgery, radiation therapy
- Where
- 59 sites in United States, Canada
- Volunteers
- 370 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colorectal Cancer, Metastatic Cancer
Floxuridine, Dexamethasone, and Irinotecan After Surgery in Treating Patients With Liver Metastases From Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as floxuridine, dexamethasone, and irinotecan, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003753
- Testing
- dexamethasone, floxuridine, irinotecan hydrochloride
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Convergence Insufficiency Intermittent Exotropia (CI-IXT)
S-BLR Versus C-BLR for CI-IXT in Children
This is a multi-center, randomized single-blind controlled trial to compare the effectiveness of S-BLR with C-BLR for the treatment of CI-IXT in children.
- Trial name
- SCCIXT (NCT04064112)
- Testing
- S-BLR, C-BLR
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chen Zhao
Anesthesia, Local, Prolapse
Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
The purpose of this study is to assess whether the transversus abdominis plane block (Tap block) is different than the oral postoperative pain medications in controlling pain after robotic sacrocolpopexy.
- Conditions
- Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal
- Trial name
- SACROTAP (NCT04440475)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ProMedica Health System
Knee Osteoarthritis
Comparison of Conventional and Cooled Radiofrequency Ablation in Knee Osteoarthritis
The aim of this study was to examine and compare the effects of conventional and cooled radiofrequency ablation on pain and disability levels in patients with knee pain resistant to other treatments due to knee osteoarthritis.
- Trial name
- NCT06863181
- Testing
- Radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Tonsillectomy, Preoperative Care
Screen-delivered Augmented-reality Preparation and Anxiety Before Pediatric Adenotonsillectomy in China
Whether a nonwearable, screen-delivered augmented-reality animation adds measurable benefit to supportive pediatric perioperative care remains uncertain.
- Conditions
- Tonsillectomy, Preoperative Care, Anxiety
- Trial name
- NCT07760571
- Testing
- Screen-delivered augmented-reality group, Usual Care Group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Central South University
Colorectal Cancer
Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00006366
- Testing
- fluorouracil, irinotecan hydrochloride, conventional surgery
- Where
- 235 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
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