Clinical trials: conventional surgery, completed
Perioperative Analgesia in Endometriosis
Influence of Intraoperative Nociception Guided Analgesia on Perioperative Total Analgesic Requirement Endometriosis
Adequate analgesia in the perioperative setting is one of the most important pillars of anesthesiology. It is generally understood that poorly managed acute postoperative pain correlates with increased morbidity, prolonged…
- Trial name
- ENDONOL (NCT06732050)
- Testing
- nociception guided treatment
- Where
- Switzerland
- Volunteers
- 125 people
- Sponsor
- Prof Urs Zingg
Peri-Implant Marginal Bone Loss, Dental Implantation
CBCT Assessment of Marginal Bone Changes With Ozone Therapy
This study examined whether adding local gaseous ozone to standard dental implant treatment could reduce early bone loss around implants. Fifty adults requiring matched implants on opposite sides of the same jaw participated.
- Trial name
- ozone-ımplant (NCT07687641)
- Testing
- Gaseous Ozone Application, Conventional Implant Placement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Cervical Cancer, Venous Thromboembolism
People's Hospital of Xinjiang Uygur Autonomous Region
Objective: To evaluate the impact of enhanced recovery after surgery (ERAS)-based nursing intervention on venous thromboembolism (VTE) and lymphedema after radical hysterectomy for cervical cancer.
- Conditions
- Cervical Cancer, Venous Thromboembolism, Lymphedema
- Trial name
- NCT07612865
- Testing
- ERAS group
- Where
- China
- Volunteers
- 160 people
- Sponsor
- People's Hospital of Xinjiang Uygur Autonomous Region
Ischemic Stroke
Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China
The SAMMPRIS suggested that aggressive treatment was superior to intravascular stenting in patients with severe symptomatic intracranial atherosclerotic stenosis (ICAS) due to high complication rate in patients in stenting group.
- Trial name
- NCT01968122
- Testing
- intravascular stent therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongrong Miao
Lacrimal Duct Obstruction
A Comparative Study of Two Endoscopic Operations for Lacrimal Duct Obstruction
To compare the clinical effects between the silicone nasolacrimal intubation under nasoendoscopy and dacryocystorhinostomy on patients with lacrimal duct obstruction.
- Trial name
- ACSOTEOFLDO (NCT02636257)
- Testing
- Recessive Spherical Headed Silicone Intubation, Dacryocystorhinostomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Diabetes, Obesity
Influence of Bariatric Surgery on Serum Levels of 26RFa
The 26RFa was recently discovered in the hypothalamus. In rodents it seems to be related to glucose metabolism and obesity. However, no data exists in obese patients or in patients with diabetes.
- Trial name
- RFa-Ba-S (NCT01982019)
- Testing
- Meal test taking and hormones measure including 26RFa
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Rouen
Coronary Disease
Randomized Comparison of MynxGrip Vascular Closure Device and Manual Compression for Closure After Femoral Access Angiography. The Closure Devices Used in Every Day Practice Study, CLOSE-UP III Trial
Is the MynxGrip (test device) non-inferior to manuel compression (standard comparator) in the incidence of adverse access site related events in-hospital, at 30 days and at 6 months.
- Trial name
- CLOSE-UP III (NCT02237430)
- Testing
- MynxGrip, Manual compression
- Where
- Denmark
- Volunteers
- 869 people
- Sponsor
- Aarhus University Hospital Skejby
Prostate Cancer
Radical Prostatectomy in Treating Patients With Locally Advanced Prostate Cancer
RATIONALE: Radical prostatectomy may be an effective treatment for locally advanced prostate cancer. PURPOSE: Phase II trial to study the effectiveness of radical prostatectomy in treating patients who have locally advanced…
- Trial name
- NCT00027794
- Testing
- conventional surgery
- Where
- 5 sites in Belgium, Italy and 1 more
- Volunteers
- 40 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Distal Radius Fractures
Volar Locking Plate vs Fragment Specific Fixation in Wrist Fractures
The treatment of unstable, non-reducible distal radial fractures is still controversial. The aim of the present study is to compare the subjective, clinical and radiographic outcome of the TriMed fragment-specific system with a…
- Trial name
- NCT01311531
- Testing
- Open reduction and fixation with TriMed fragment-specific system, Open reduction and fixation with TriMed volar locking plate
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Anxiety Disorder, Breast Cancer
Hypnosis in Reducing Pain and Other Side Effects in Women Undergoing Surgery for Breast Cancer
RATIONALE: Hypnosis may be effective in reducing pain and other side effects in women undergoing surgery for breast cancer. PURPOSE: This clinical trial is studying how well hypnosis works in reducing pain and other side effects…
- Conditions
- Anxiety Disorder, Breast Cancer, Nausea and Vomiting, Pain
- Trial name
- NCT00748267
- Testing
- questionnaire administration, hypnotherapy, therapeutic conventional surgery
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Breast Cancer
Ritonavir and Its Effects on Biomarkers in Women Undergoing Surgery for Newly Diagnosed Breast Cancer
RATIONALE: Ritonavir may stop the growth of tumor cells by blocking some of the enzymes needed for cancer cell growth. Studying samples of blood and tissue from patients with breast cancer in the laboratory may help doctors learn…
- Trial name
- NCT01009437
- Testing
- ritonavir, therapeutic conventional surgery
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Breast Cancer
Tamoxifen With or Without Combination Chemotherapy in Treating Postmenopausal Women With Operable Invasive Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen.
- Trial name
- NCT00002581
- Testing
- cyclophosphamide, fluorouracil, methotrexate
- Where
- 9 sites in United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Scottish Cancer Therapy Network
Lung, Lung Cancer (NSCLC)
Tubeless VATS for Lung Cancer Surgery
This prospective cohort study evaluates lung injury, long-term clinical outcomes, and environmental impacts of tubeless video-assisted thoracic surgery (VATS) compared with conventional intubated VATS for lung cancer resection.
- Conditions
- Lung, Lung Cancer (NSCLC), VATS
- Trial name
- NCT07057531
- Testing
- Tubeless thoracic surgery
- Where
- China
- Volunteers
- 73 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Neoadjuvant Ifosfamide, Doxorubicin, Gemcitabine, and Cisplatin in Treating Patients Who Are Undergoing Radical Cystectomy for Locally Advanced Carcinoma (Cancer) of the Urothelium
RATIONALE: Drugs used in chemotherapy, such as ifosfamide, doxorubicin, gemcitabine, and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00080795
- Testing
- filgrastim, cisplatin, doxorubicin hydrochloride
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Implant Tissue Failure
One-abutment One-time for Immediate Restoration Procedure in the Esthetic Zone
Objectives: The aim of this randomized control trial was to compare immediate restoration procedure with a one abutment one-time technique using a conventional versus full digital workflow.
- Trial name
- IONE (NCT04139512)
- Testing
- guided surgery, conventionnel implant placement
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Liege
Airway Management
Comparison of I-gel LMA, Classical LMA With a New Supraglottic Airway the Baska Mask® in Urological Surgery
The most used airway management strategies are different types of supraglottic airway devices (SAD) for transurethral resection of bladder and ureteroscopy in urological surgery .
- Trial name
- BCIM (NCT03002857)
- Testing
- LMA-C, Baska Mask, I-gel
- Volunteers
- 150 people
- Sponsor
- Adiyaman University Research Hospital
Dental Implant Placement
Implant Placement in Combination With Connective Tissue Grafting
Suitable subjects who were in need of implant placement were randomised between two groups; Group-A (NA=23) received crestal implant placement.
- Trial name
- CTG_implant (NCT03728283)
- Testing
- implant placement in combination with connective tissue grafting, Implant placement
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Colorectal Cancer
Laparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon Cancer
RATIONALE: Less invasive types of surgery may help reduce the number of side effects and improve recovery. It is not yet known which type of surgery is more effective for colon cancer.
- Trial name
- NCT00002575
- Testing
- conventional surgery, laparoscopic surgery
- Where
- 158 sites in United States, Canada and 1 more
- Volunteers
- 810 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Sarcoma
MRI Sarcoma Non Invasive Thermometry
RATIONALE: Hyperthermia therapy kills tumor cells by heating them to several degrees above body temperature. Using MRI to measure heat may help to determine the effectiveness of hyperthermia therapy.
- Trial name
- NCT00093509
- Testing
- doxorubicin hydrochloride, ifosfamide and mesna, hyperthermia treatment with an MRI Compatible Radiofrequency Extremity Hyperthermia Applicator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mark Dewhirst
Laparoscopic Cholecystectomy
Pain in Single Incision Laparoscopic Surgery Cholecystectomy
The attempt to further reduce the operative trauma in laparoscopic cholecystectomy led in new techniques, as Natural Orifice Transluminal Endoscopic Surgery (NOTES) and Single Incision Laparoscopic Surgery (SILS).
- Trial name
- NCT00872287
- Testing
- Laparoscopic Cholecystectomy, SILS
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- G. Hatzikosta General Hospital
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