Clinical trials: flow cytometry, completed
Breast Cancer
Diet and Exercise or Normal Care in Overweight or Obese Women Who Have Undergone Treatment for Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Studying diet and exercise interventions in overweight and obese patients with breast cancer may help doctors learn more about how to help patients lose weight and change their body composition.
- Trial name
- NCT00689975
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Sheffield Hallam University
Pancreas Cancer
Perioperative Immune Function and Clinical Complications in Pancreaduodenectomy
Perioperative immunologic signatures can predict the risk of postoperative complications. The results will be puplished as two smanuscripts.
- Trial name
- NCT04774198
- Testing
- blood sample
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia
Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia
RATIONALE: Monoclonal antibodies, such as alemtuzumab and rituximab, can kill chronic lymphocytic leukemia (CLL) cells and are effective therapies for this disease.
- Conditions
- B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Stage 0 Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia
- Trial name
- NCT01269385
- Testing
- alemtuzumab, rituximab, PGG beta-glucan
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic
Acute Coronary Syndome
Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?
Background Acute coronary syndrome (ACS) is a term representing all diseases related to reduction in blood flow to the heart characterised by clot formation over a segment of blood vessel narrowing.
- Trial name
- PLATE NOX (NCT02169596)
- Testing
- Ticagrelor, EndoPAT - endothelial assessment
- Where
- United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Neuroblastoma, Sarcoma
Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma
Background: Pediatric solid tumors (Ewing's sarcoma, rhabdomyosarcoma, and neuroblastoma) are often difficult to cure with standard treatment.
- Conditions
- Neuroblastoma, Sarcoma, Rhabdomyosarcoma-Embryonal, Rhabdomyosarcoma- Alveolar
- Trial name
- NCT00923351
- Testing
- Tumor Purged/CD25 Depleted Lymphocytes, Tumor Purged/CD25 Depleted Lymphocytes with Tumor Lysate/KLH Pulsed Dendritic Cell Vaccine, rhIL-7
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute (NCI)
Allergy
Flow Cytometry Applied to the Diagnosis of Peri-anaesthesic Reactions
To assess diagnostic accuracy of flow cytometry applied to the diagnosis of allergy to neuro-muscular blockers and to the determination of the neuro-muscular blocker (NMB) which may be used for an ulterior anaesthesia in case of…
- Trial name
- CYPREANE (NCT01305161)
- Testing
- Blood simple
- Where
- 4 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Limoges
Colorectal Cancer
Immune Checkpoints in Intraabdominal Ascites Fluid
Colorectal cancers are the third most common type of cancer in the world. Peritoneal carcinomatosis and intraabdominal acid development occur in advanced stages of colorectal cancers.
- Trial name
- NCT04540159
- Testing
- Flow-cytometric analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Training and Research Hospital
Plasma Cell Disorder
Evaluation of the Plasma Cell Disorders Panel on the BD FACSLyric™ Flow Cytometer
Multi-site, prospective performance study to determine equivalency between the investigational OneFlow PCD panel on the FACSLyric system versus the final clinical diagnosis.
- Trial name
- NCT05032339
- Testing
- IUO Plasma Cell Disorders Panel
- Where
- 5 sites in United States, Portugal and 3 more
- Volunteers
- 208 people
- Sponsor
- Becton, Dickinson and Company
Heart Transplant Infection, Kidney Transplant Infection
CMV T Cell Immunity in Pediatric Solid Organ Transplant Recipients
CMV infection and disease remain a significant clinical challenge for pediatric solid organ transplant (SOT) recipients. Current prevention strategies are limited to prophylaxis in which antiviral medication is administered for a…
- Conditions
- Heart Transplant Infection, Kidney Transplant Infection, Liver Transplant Infection, CMV
- Trial name
- NCT03924219
- Testing
- CMV T cell Immunity Assay
- Where
- 12 sites in United States
- Volunteers
- 161 people
- Sponsor
- Vanderbilt University Medical Center
Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Bortezomib and Topotecan in Treating Patients With Advanced Solid Tumors
RATIONALE: Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as topotecan, work in different ways to stop the growth of tumor cells, either by…
- Trial name
- NCT00388089
- Testing
- bortezomib, topotecan hydrochloride, flow cytometry
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Davis
Myeloproliferative Syndrome
Efficacy of Heat-shock Protein (HSP) Inhibitors in Myeloproliferative Syndromes (MPS)
Heat-shock proteins (HSP) have been very highly conserved throughout the evolution of species and are characterized by their chaperone function, thanks to their ability to prevent aggregation and to promote the renaturation/break…
- Trial name
- HSP-SMP (NCT02873832)
- Testing
- Blood sample, Flow cytometry, western blot
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pancreatic Cancer
Study of Intratumoral Hypoxia Using Pre-operative Administration of Pimonidazole
This study involves the administration of a hypoxia marker, pimonidazole hydrochloride, taken orally approximately 24 hours before surgical resection of a pancreatic tumor in order to identify areas of lower oxygen content on…
- Trial name
- NCT01248637
- Testing
- Pimonidazole hydrochloride
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Advanced Cancer, Healthy
Laboratory Testing for Tie-2 Expressing Monocytes (TEMs) in Blood
Tie-2 expressing monocytes (TEMs) are a specific type of blood cell that are present in healthy individuals and in people with cancer.
- Trial name
- NCT01543841
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Breast Cancer
The Relationship Between the Differences in Blood Cytokine Values in Breast Cancers.
While classification of malignant breast tumors has traditionally been made according to their histological appearance, nowadays some subtypes have been defined according to their molecular features.
- Trial name
- NCT04540224
- Testing
- Flow-Cytometric analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
HER2-positive Breast Cancer, Stage III Ovarian Epithelial Cancer
Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer
RATIONALE: Vaccines may help the body build an effective immune response to kill tumor cells. Colony-stimulating factors, such as GM-CSF, may increase the number of immune cells found in bone marrow or peripheral blood.
- Conditions
- HER2-positive Breast Cancer, Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor, Stage IIIA Breast Cancer
- Trial name
- NCT00436254
- Testing
- pNGVL3-hICD vaccine, sargramostim, flow cytometry
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Washington
Acute Myocardial Infarction (AMI), Acute Coronary Syndrome (ACS)
Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers
Oxygen treatment is widely used in acutely ill patients, both pre-hospital and in hospital. The indication for oxygen is sometimes unquestionable, such as in many hypoxic patients, but in other situations its use is more of a…
- Conditions
- Acute Myocardial Infarction (AMI), Acute Coronary Syndrome (ACS), ST Elevation (STEMI) Myocardial Infarction, Ischemic Reperfusion Injury
- Trial name
- DETO2X-bio (NCT02290080)
- Testing
- Oxygen
- Where
- 2 sites in Sweden
- Volunteers
- 175 people
- Sponsor
- Karolinska Institutet
Allergy
Interest of Flow Cytometry for the Diagnosis, the Follow up and Specific Immunotherapy (SIT) Arrest of Hymenoptera Venom Allergy
The aim of this study is to show that flow cytometry can be an accurate tool to help physicians regarding the diagnosis, the SIT decision and the SIT arrest of hymenoptera venom allergy.
- Trial name
- Cytoven (NCT00805402)
- Testing
- flow cytometry
- Where
- France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Limoges
Prosthesis-Related Infections, Arthroplasty, Replacement, Hip
Exploring Novel Diagnostic Tools for Periprosthetic Joint Infection
Joint replacement is a valuable surgical intervention that improves quality of life, provides pain relief, and restores function of patients.
- Conditions
- Prosthesis-Related Infections, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- VECTOR-PJI (NCT05582460)
- Testing
- Reporter Gene Assay, Flow Cytometry
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Rijnstate Hospital
Castleman Disease, Angiofollicular Lymphoid Hyperplasia
Unlock the Cell: Castleman's Disease Flow Cytometry Study
Castleman disease, a rare lymphoproliferative disorder, is characterized by inflammatory cytokine production and multiple organ system dysfunction.
- Conditions
- Castleman Disease, Angiofollicular Lymphoid Hyperplasia, GLNH, Hyperplasia
- Trial name
- NCT02853968
- Testing
- Blood draw/buccal swab
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Patients in Good Health
Inflammatory Cytokines Profile in Individuals Subjected to Surgical Procedures Using Propofol or Isoflurane
The aim of this study is to assess the profile of cytokines IL-1beta, IL-6, IL-8, IL-10, IL-12 and TNF-alpha under inhalation anesthesia with isoflurane and intravenous anesthesia with propofol in healthy patients subjected to…
- Trial name
- NCT01111227
- Testing
- Propofol and isoflurane
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp