Clinical trials: flow cytometry, completed
Acute Myeloid Leukemia
Immune Checkpoint Receptors in AML-Leukemic Initiating Cells
This project aim at deciphering immune mechanisms that allow the immunoescape of AML initiating cells.
- Trial name
- ICAML-LIC (NCT03449745)
- Where
- France
- Volunteers
- 199 people
- Sponsor
- University Hospital, Bordeaux
Primary Peritoneal Cavity Cancer, Stage I Endometrial Carcinoma
EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer
This phase II trial is studying how well EF5 works in finding oxygen in tumor cells of patients who are undergoing surgery or biopsy for cervical, endometrial, or ovarian epithelial cancer.
- Conditions
- Primary Peritoneal Cavity Cancer, Stage I Endometrial Carcinoma, Stage I Ovarian Epithelial Cancer, Stage IA Cervical Cancer
- Trial name
- NCT00107445
- Testing
- EF5
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Cardiovascular Function
Investigation of the Influence of Gender on Cardiovascular Function
Inflammation is a key initiating and damaging factor in many illnesses including infection, arthritis and cancer but also of particular relevance to this study in diseases of the heart and blood vessels (i.e.
- Trial name
- NCT01582321
- Testing
- Typhoid vaccine, Cantharidin
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission
Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia
This clinical trial is studying biomarkers as a diagnostic tool in samples from younger patients with B-cell acute lymphoblastic leukemia.
- Conditions
- B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic Leukemia
- Trial name
- NCT01540578
- Testing
- laboratory biomarker analysis
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Children's Oncology Group
Crohn Disease
Histopathologic and Lymphocyte Subpopulations Evaluation of the Upper Gastrointestinal Tract of Crohn's Disease
Inflammatory bowel disease (IBD) comprises a series of disorders of unknown cause, such as ulcerative colitis (UC), Crohn's disease (CD) and indeterminate colitis (IC), associated with an over-the-top immune response that…
- Trial name
- CROHNLY (NCT05874349)
- Testing
- General variables, Clinical activity, Laboratory data
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Mutua de Terrassa
Recurrent Colon Cancer, Recurrent Gastric Cancer
Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer
RATIONALE: Vaccines made from a gene-modified virus may help the body build an effective immune response to kill tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of vaccine therapy in treating…
- Conditions
- Recurrent Colon Cancer, Recurrent Gastric Cancer, Recurrent Pancreatic Cancer, Recurrent Rectal Cancer
- Trial name
- NCT01191684
- Testing
- laboratory biomarker analysis, enzyme-linked immunosorbent assay, flow cytometry
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- City of Hope Medical Center
Acute Leukemia
Assessment of Antithrombin III, Protein C, Protein S and D-dimer in Acute Leukemia
The goal of this observational study is to evaluate the levels of Antithrombin III, Protein C, Protein S, and D-dimer in patients with Acute Leukemia (Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)).
- Trial name
- NCT07036809
- Testing
- Antithrombin III, Protein C, Protein S
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia
Flow Cytometric Analysis of Peripheral Blood Neutrophil Myeloperoxidase Expression and Myelodysplastic Syndromes
Myelodysplastic syndromes (MDS) constitute a heterogeneous group of clonal bone marrow neoplasms that predominate in the elderly, with a median age at diagnosis of 70 years.
- Trial name
- MPO-MDS-PILOT (NCT03363399)
- Testing
- Flow cytometry analysis of neutrophil myeloperoxidase expression
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Membranous Nephropathy
Effect of B-cell Depleting Therapies on PLA2R-specific B Cells in Patients With Membranous Nephropathy
This is a non-pharmacological interventional monocentric study to primarily assess the levels of circulating phospholipase A2 receptor (PLA2R)-specific B cells in patients with PLA2R-mediated MN enrolled in the ORION and MONET…
- Trial name
- DEEPER (NCT06994468)
- Testing
- Flow-cytometry tetramer-based antigen-bait assay
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Fetomaternal Hemorrhage, Neonatal Anemia
Identification of Early Predictors of Fetomaternal Hemorrhage
Objectives: 1) To determine risk factors for fetomaternal hemorrhage. 2) To identify a cost-effective method to detect fetomaternal hemorrhage prior to significant fetal anemia.
- Trial name
- NCT01232387
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atheroma; Myocardial
Plaque Erosion Prospective Study ii
Plaque erosion is associated with myocardial infarction (MI) in about 30% of cases and may require a different management approach to plaque rupture.
- Trial name
- PEPSii (NCT04701385)
- Testing
- Optical Coherence Tomography (OCT)
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Delirium
Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults
(From NIH reporter) Each year >16 million older Americans undergo anesthesia and surgery, and up to 40% of these patients develop postoperative cognitive dysfunction (POCD), a syndrome of postoperative thinking and memory…
- Trial name
- INTUIT (NCT03273335)
- Testing
- Millipore biomarker assay plate
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Duke University
Nonneoplastic Condition, Precancerous Condition
Human Papilloma Virus Infection in HIV-Positive Indian Men Who Have Sex With Men
RATIONALE: Gathering information about human papilloma virus (HPV) infection in HIV-positive men who have sex with men may help doctors learn more about the disease.
- Trial name
- NCT00919997
- Testing
- DNA analysis, polymerase chain reaction, fluorescence activated cell sorting
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- AIDS Malignancy Consortium
Leukemia
Biomarkers in Samples From Patients With Chronic Lymphocytic Leukemia Treated on Clinical Trial ECOG-2997
RATIONALE: Studying samples of cells in the laboratory from patients with cancer may help identify biomarkers related to cancer. It may also help doctors learn how patients respond to treatment.
- Trial name
- NCT00899873
- Testing
- cytogenetic analysis, flow cytometry, fluorescence activated cell sorting
- Volunteers
- 225 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Cardiovascular Diseases
PLATELET TISSUE FACTOR AS BIOMARKER OF THROMBOTIC RISK IN CORONARY ARTERY DISEASE PATIENTS (TRIT-ONE)
Enhancing thrombotic risk stratification in patients with coronary artery disease (CAD) is crucial for the prevention and management of cardiovascular disease.
- Trial name
- TRIT-ONE (NCT06919731)
- Testing
- whole blood flow cytometry analisys
- Volunteers
- 600 people
- Sponsor
- Centro Cardiologico Monzino
Surgical Wound Infection
Local Warming of Surgical Incisions
The purpose of this study is to determine if local warming of surgical wounds improves healing and helps prevent infection. The investigators want to see if warming surgical incisions improves oxygen levels and healing in skin…
- Trial name
- NCT01026259
- Testing
- Warming of surgical incision, Warming dressing without actual warming
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Washington
Idiopathic Thrombocytopenic Purpura
Study of Platelets Sialylation by Flow Cytometry for the Differential Diagnosis of ICT
Idiopathic thrombocytopenic purpura (ITP) is the most frequent auto-immune cytopenia. There is no specific biological marker and the diagnosis often results from the exclusion of other differential diagnoses, notably inherited…
- Trial name
- SYMPATHIC (NCT03421392)
- Testing
- non interventional study
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma
Iodine I 131 Tositumomab and Fludarabine Phosphate in Treating Older Patients Who Are Undergoing an Autologous or Syngeneic Stem Cell Transplant for Relapsed or Refractory Non-Hodgkin's Lymphoma
This phase I trial studies the side effects and best dose of fludarabine (fludarabine phosphate) when given together with iodine I 131 tositumomab in treating older patients who are undergoing an autologous or syngeneic stem cell…
- Conditions
- Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma
- Trial name
- NCT00110071
- Testing
- fludarabine phosphate, peripheral blood stem cell transplantation, iodine I 131 tositumomab
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Fred Hutchinson Cancer Center
Breast Cancer, Chronic Myeloproliferative Disorders
Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell Transplant
RATIONALE: Collecting and storing samples of blood, urine, and tissue from patients undergoing a donor stem cell transplant to test in the laboratory may help the study of graft-versus-host disease in the future.
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease
- Trial name
- NCT00900406
- Testing
- gene expression analysis, microarray analysis, polymorphism analysis
- Where
- 3 sites in United States
- Volunteers
- 190 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Glomerulonephritis Acute
Urinary T Lymphocytes Predict Renal Flares in Patients With Inactive ANCA-associated Glomerulonephritis
Urinary CD4+ and CD8+ T lymphocytes may predict renal flares in patients with inactive ANCA-associated vasculitis and thus serve as early non-invasive biomarkers.
- Trial name
- PRE-FLARED (NCT04428398)
- Testing
- Analysis of urine samples with flow cytometry
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany