Clinical trials: rTMS
Changes in EEG During and After Magnetic Stimulation
The Effect of Repetitive Transcranial Magnetic Stimulation on Brain Activity in Healthy Human Volunteers
The proposed study is designed to determine whether small changes in the positioning of a transcranial magnetic stimulation coil over the frontal parts of the brain cause different patterns of brain activation measured by…
- Trial name
- ERP (NCT01369264)
- Testing
- true left high frequency
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Alzheimer Disease, Mild Dementia
Acute Effect of Low-intensity Gamma rTMS on Cognitive and EEG Parameters in Adults With Mild Dementia by Alzheimer's Disease
Neurocognitive disorders have a growing prevalence and impact on public health; their main etiology corresponds to Alzheimer's disease. To date, there is no treatment that can reverse neuronal damage in these pathologies.
- Trial name
- NCT05784298
- Testing
- low-intensity rTMS
- Where
- Mexico
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Essential Tremor
Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor
The purpose of this study is to evaluate the efficacy and electrophysiology of repetitive transcranial magnetic stimulation in the treatment of essential tremor.
- Trial name
- rTMS (NCT06145932)
- Testing
- real rTMS
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Cocaine Use, Cocaine Dependence
Effect of rTMS on Neurotrophines Levels in CUD
Brief Summary: Background: Cocaine use disorders (CUD) is a multifactoral disease, involving several brain areas. One of the most investigated is the Dorsolateral Prefrontal Cortex (DLPFC) involved in impulsiveness control.
- Conditions
- Cocaine Use, Cocaine Dependence, Cocaine Abuse, Neurotropism
- Trial name
- BDNFcoca (NCT05824221)
- Testing
- rTMS
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Healthy
Non-invasive Cerebellar Stimulation on Motor Learning
A crossover trial with healthy volunteers will be conducted. Six sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT02559518
- Testing
- tDCS, rTMS, pp-TMS assessment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Smoking Cessation, Addiction
Evaluation of the Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) Low-frequency on Craving in Smoking Dependence
The fight against smoking is a public health priority. Without help, fewer than 5% of des smokers are abstinent at 12 months after smoking cessation.
- Trial name
- rTMS TABAC (NCT02812810)
- Testing
- active rTMS
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Stroke
A Novel Approach for Brain Stimulation in Severe Stroke
The long-term goal of this project is to develop upper limb rehabilitation interventions that can be utilized for stroke survivors, specifically survivors with more severe limitations in use of their affected upper limb.
- Trial name
- NCT03868410
- Testing
- New Repetitive Magnetic Stimulation (rTMS) Approach, Conventional Repetitive Magnetic Stimulation (rTMS) Approach
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Parkinson, Parkinson Disease
Cerebellar rTMS Theta Burst for Dual-task Walking in Parkinson's Disease
Objective of the study: To test the efficacy of theta burst cerebellar stimulation on dual task walking in Parkinson's disease using a cross-over design and wearing sensors technology Design: Twenty Parkinson's disease patients…
- Conditions
- Parkinson, Parkinson Disease, Gait Disorders, Neurologic, Parkinsonism
- Trial name
- NCT04238000
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Europea di Ricerca Biomedica Ferb Onlus
Major Depressive Disorder
Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD)
An open label study to assess the safety, tolerability, and effects of intranasal Ketamine in combination with rTMS for patients with treatment-resistant major depressive disorder (TRD).
- Trial name
- NCT04352621
- Testing
- intranasal ketamine, rTMS treatment
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Major Depressive Disorder
Antidepressive Effect on 5 Herz (Hz) rTMS Over Dorsomedial Prefrontal Cortex and Left Dorsolateral Prefrontal Cortex
This study evaluates the efficacy of 5Hz repetitive Transcranial Magnetic Stimulation (rTMS) over Left Dorsolateral Prefrontal Cortex and Dorsomedial Prefrontal Cortex on Major Depressive Disorder (MDD).
- Trial name
- NCT03571412
- Testing
- repetitive Transcranial Magnetic Stimulation
- Volunteers
- 26 people
- Sponsor
- Universidad Autonoma de Queretaro
Stuttering, Adult
The Effects of Brain Stimulation on Speech Fluency in Adults Who Stutter
The project is leading to investigate the effects of neuromodulation techniques on speech fluency among adults who stutter (AWS).
- Trial name
- NCT05472181
- Testing
- rTMS (Repetitive TMS), Speech training
- Where
- Hong Kong
- Volunteers
- 18 people
- Sponsor
- The University of Hong Kong
Transcranial Magnetic Stimulation, Repetitive, Depression - Major Depressive Disorder
Effect of Theta-burst rTMS Therapy on the Clinical and Cognitive Symptoms of Patients With Therapy Resistant Depression and Response Prediction With Neuroimaging Methods.
The primary aim of the study is to find the combination of neuroimaging-related markers, demographics, and clinical characteristics that predict the response of patients with therapy-resistant depression to theta-burst rTMS…
- Trial name
- TMS-DEP-2024 (NCT07207239)
- Testing
- repetative Transcranial Magnetic Stimulation (rTMS), theta-burst protocol
- Where
- Hungary
- Volunteers
- 54 people
- Sponsor
- Semmelweis University
Obsessive-Compulsive Disorder
The Use of Magnetic Brain Stimulation to Treat Obsessive Compulsive Disorder, a Pilot Study
The purpose of this study is two-fold: first, to observe the effect of one session of repetitive transcranial magnetic stimulation (rTMS) on the error-prediction abilities of patients with obsessive compulsive disorder (OCD) as…
- Trial name
- NCT02541812
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Primary Dysmenorrhea
Evaluation of the Effect of TMS on Primary Dysmenorrhea
Based on the pain threshold and visual simulation score, primary dysmenorrhea patients will be divided into treatment effective group or non-effective group.According to the functional magnetic resonance imaging, the…
- Trial name
- NCT04168489
- Testing
- active rTMS
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Attention-Deficit/Hyperactivity Disorder (ADHD)
Finding Alternatives to Standard Treatment for Attention-Deficit Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) is characterized by poor attention, impulsivity, hyperactivity and emotional-motivational dysregulation.
- Trial name
- FAST-ADHD (NCT04532190)
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
CRPS (Complex Regional Pain Syndromes)
The Effectiveness of Conservative Treatment in Patients With Complex Regional Pain Syndrome.
The aim of the study is to investigate and improve non-pharmacological rehabilitation methods for patients with Complex Regional Pain Syndrome (CRPS) to reduce pain and restore work and functional capacity to lower overall…
- Trial name
- NCT07208825
- Testing
- rTMS, Basic physical therapy treatment, Functional neurology
- Where
- Finland
- Volunteers
- 156 people
- Sponsor
- Oulu University Hospital
Migraine, Transcranial Magnetic Stimulation Repetitive
Individualized Location-based rTMS for Migraine Treatment: A Multicenter Clinical Study
For migraine patients experiencing at least four attack days per month and undergoing transcranial magnetic stimulation (TMS) treatment, a randomized, double-blind controlled trial is conducted, dividing participants into a…
- Trial name
- individua rTMS (NCT07086274)
- Testing
- Individualized location-based Repetitive Transcranial Magnetic Stimulation, Traditional location-based Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 152 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Sleep Disturbance
An Integration of Tai Chi and Repetitive Transcranial Magnetic Stimulation for Sleep Disturbance in Older Adults
The investigators designed an RCT aimed at 1) exploring the effectiveness of combining TC with rTMS for synergistically improving sleep disturbances in community-dwelling older adults, 2) investigating the mediating roles of…
- Trial name
- NCT05808517
- Testing
- Tai Chi, repetitive transcranial magnetic stimulation
- Where
- Hong Kong
- Volunteers
- 38 people
- Sponsor
- The Hong Kong Polytechnic University
Cortical Excitability, Primary Motor Cortex
rTMS Induced Reduction in M1 Excitability
When learning a new skill, much of the improvement comes from small alterations the brain makes with each repetition during practice, but this isn't the only time that improvements are made during the learning process.
- Conditions
- Cortical Excitability, Primary Motor Cortex, Motor Skills
- Trial name
- NCT07588113
- Testing
- rTMS
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Indiana University
Depressive Disorder, Major Depressive Disorder, Adolescence
Comparing 10 Hz rTMS and iTBS for Adolescent Depression
This trial compares two transcranial magnetic stimulation (TMS) protocols-10 Hz rTMS and intermittent theta burst stimulation (iTBS)-in adolescents with major depressive disorder.
- Trial name
- NCT07873060
- Testing
- 10 Hz Repetitive Transcranial Magnetic, Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University
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