Clinical trials: rTMS
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804296
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Paul E. Croarkin
Schizophrenia
Bilateral Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations Results
The primary purpose of this study was to conduct fMRI neuroimaging studies prior to and subsequent to the rTMS intervention. The intent was to ascertain changes in regional brain activation and connectivity that most robustly…
- Trial name
- NCT04548622
- Testing
- Magstim Rapid 2 system triggering Magstim Super Rapid system
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Essential Tremor
A Pilot Study to Assess the Effects of Pre-SMA LF-rTMS for the Treatment of Essential Tremor
The purpose of this study is to determine the effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (LF r-TMS) of the pre-Supplementary Motor Area (pre-SMA) on tremor as measured by the tremor rating scale (TRS)…
- Trial name
- NCT02763865
- Testing
- MagVenture MagProx100 Stimulator with a Cool-B65 A/P coil
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Aging
Using TMS to Increase Executive Function in Older Adults
Cognitive decline and dementia have become important public health issues in our time as medical science has increased lifespan and our society becomes progressively older.
- Trial name
- WMTMS (NCT02767323)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Duke University
Psychomotor Retardation, Psychomotor Slowing
Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders
Psychomotor slowing may occur in major psychiatric disorders, such as major depressive disorders or schizophrenia spectrum disorders. It refers to slowing of fine motor skills, motor planning and gross motor behavior.
- Conditions
- Psychomotor Retardation, Psychomotor Slowing, Schizophrenia and Related Disorders, Major Depressive Disorder
- Trial name
- NCT03275766
- Testing
- DLPFC facilitatory, SMA inhibitory, SMA facilitatory
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Bern
Opioid Use Disorder
Transcranial Magnetic Stimulation (rTMS) as a Tool to Decrease Pain and Improve Functioning
Despite the availability of opioid replacement therapies, many opioid use disordered Veterans are not able to remain abstinent. Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulation technique with…
- Trial name
- TMS (NCT03821337)
- Testing
- repetitive Trans Magnetic Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Office of Research and Development
Pain
Role of the Supraspinal Opioidergic Circuit in Prefrontal TMS-Induced Analgesia
Studies have shown that transcranial magnetic stimulation (TMS), a non-invasive form of brain stimulation, can reduce pain in the laboratory and in the clinic.
- Trial name
- NCT01643798
- Testing
- Real rTMS
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Schizophrenia
Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia
This will be a single site pilot study. 20 subjects with EPP (Early Phase Psychosis), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past 10 years, will be enrolled.
- Trial name
- rTMS-FPCC (NCT04309370)
- Testing
- 20 Hz rTMS
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Parkinson's Disease
Cognitive Dysfunction in Parkinson's Disease
This study plans to learn more about the brain function related to thinking problems in individuals with Parkinson's disease.
- Trial name
- NCT02346708
- Testing
- Real TMS
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Colorado, Denver
Obsessive-Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD)
This study will evaluate the clinical efficacy of functional Magnetic Resonance Imaging (fMRI) guided 1 Hz repetitive Transcranial Magnetic Stimulation (rTMS) applied to the Supplementary Motor Area (SMA) in OCD patients who have…
- Trial name
- NCT00106249
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- New York State Psychiatric Institute
Epilepsies, Partial
Treatment of Difficult to Control Focal Epilepsy With Repetitive Transcranial Magnetic Stimulation (rTMS)
The investigators will treat patients with fully characterized refractory unifocal neocortical epilepsy with a technique that delivers magnetic waves (transcranial magnetic stimulation, TMS) to the region that causes the…
- Trial name
- NCT01745952
- Testing
- figure-of-eight active rTMS coil, round active rTMS coil
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Motor Function
Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients
In this study investigator's aim to assess the effect of a type of non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) in conjunction with fluoxetine on motor recovery after stroke.
- Trial name
- NCT02208466
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS), Fluoxetine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Spaulding Rehabilitation Hospital
Schizophrenia
A Double-Blind Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Negative Symptoms in Schizophrenia
There is pilot data to suggest the therapeutic value of rTMS applied to the left prefrontal cortex in the treatment of negative symptoms.
- Trial name
- rTMS (NCT00168311)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Australia
- Volunteers
- 22 people
- Sponsor
- The Alfred
Amygdala Activation
Effects of Connectivity-based rTMS and State-Dependency on Amygdala Activation
Posttraumatic stress disorder (PTSD) is a highly debilitating disease with response rates to pharmacological treatment rarely exceeding 60%.
- Trial name
- ConnecTMS (NCT03746405)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Mild Cognitive Impairment
Network-guided TMS in Early Alzheimer's Disease
The proposed research will test a novel network-based neurostimulation approach using MRI-derived measures of brain connectivity to establish target sites for neurostimulation and test for the enhancement of memory function…
- Trial name
- NetTMS (NCT04549155)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Duke University
Focal Dystonia
rTMS and Retraining in Focal Hand Dystonia
This study is exploring a new experimental procedure in dystonia called repetitive transcranial magnetic brain stimulation (TMS) combined with rehabilitation.
- Trial name
- DSS (NCT01738581)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Sensorimotor Retraining, Non-specific Therapy
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Cervical Dystonia, Spasmodic Torticollis
Identification of Optimal Stimulation Site for Cervical Dystonia Symptoms: An Exploratory Study
The overall objective of this application is to therapeutically target the dysfunctional premotor-motor interaction in dystonia-and to provide a focused treatment of specific anatomical networks in order to reduce side effects…
- Trial name
- NCT01859247
- Testing
- rTMS
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of New Mexico
Tobacco Use Disorder
Examining the Effects of Neural Stimulation on Inhibitory Control and Cigarette Smoking
The purpose of this research study is to examine the effects of theta-burst Transcranial Magnetic Stimulation on inhibitory control and smoking among adult cigarette smokers.
- Trial name
- NCT03960138
- Testing
- Intermittent Theta-burst stimulation (iTBS), Continuous Theta-burst stimulation (cTBS)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Major Depressive Disorder
Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in Depressed Teens
This research study aims to test the safety and effectiveness of repetitive transcranial magnetic stimulation (rTMS) on teens with depression.
- Trial name
- NCT01502033
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Paul E. Croarkin
Parkinson Disease With Freezing of Gait
Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait
Freezing of gait (FoG) is a common and debilitating condition in Parkinson's Disease (PD) patients. FoG is described as an episodic inability to walk, which often triggers falls, hospitalization and is an important predictor of…
- Trial name
- TMS/FOG (NCT03273270)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina