Clinical trials: therapeutic conventional surgery
Squamous Cell Carcinoma
Laryngeal Preservation in Pyriform Sinus Carcinoma
Patients were eligible if they had biopsy proven, previously untreated T3 with fixed cord involvement squamous cell carcinoma of the pyriform sinus.
- Trial name
- NCT00770393
- Testing
- induction chemotherapy, Conventionnal chemotherapy
- Where
- 7 sites in France
- Volunteers
- 71 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neuroblastoma
Chemotherapy and Surgery Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Neuroblastoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs to kill…
- Trial name
- NCT00024193
- Testing
- filgrastim, busulfan, cisplatin
- Where
- France
- Sponsor
- Children's Cancer and Leukaemia Group
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Gemcitabine and Radiation Therapy in Treating Patients With Locally Advanced Upper Gastrointestinal Cancer
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT00544193
- Testing
- gemcitabine hydrochloride, polymerase chain reaction, immunohistochemistry staining method
- Volunteers
- 16 people
- Sponsor
- City of Hope Medical Center
Clinical Decision Support System
Development and Application of a Clinical Decision Support System for Exercise Rehabilitation in Patients With Osteoporotic Vertebral Compression Fractures
This study aims to develop a clinical decision support system for exercise rehabilitation in patients with osteoporotic vertebral compression fractures, based on evidence-based recommendations for postoperative exercise…
- Trial name
- NCT07623304
- Testing
- Decision Support System: A clinical decision support system for exercise rehabilitation in patients with osteoporotic vertebral compression fractures, Basic Postoperative Care, Conventional Postoperative Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiawei Jiang
Rectal Prolapse, Pelvic Organ Prolapse (POP)
RECTOSACROUTEROPEXY vs. WELLS
The goal of this clinical trial was to compare two surgical techniques in female patients with full-thickness rectal prolapse. The main questions it aimed to answer were: 1.
- Trial name
- RSUP (NCT07673406)
- Testing
- Modified rectosacrouteropexy, Wells rectopexy
- Where
- Azerbaijan
- Volunteers
- 36 people
- Sponsor
- Azerbaijan Medical University
Alveolar Bone Resorption, Dental Implant Failure Nos
Artificial Intelligence/Computer Guided Ridge Splitting for Treating Horizontal Ridge Defects
Aim of the current randomized clinical trial is to evaluate and compare the effectiveness of computer-guided ridge splitting approach assisted by artificial intelligence versus conventional approach combined with simultaneous…
- Trial name
- NCT06135506
- Testing
- free-hand ridge splitting, AI/guided ridge splitting
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Lung Cancer
Bevacizumab, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread.
- Trial name
- NCT00025389
- Testing
- bevacizumab, carboplatin, paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Chicago
Dizziness
Vestibular Evaluation After Vestibular Schwannoma Treatment
Vestibular schwannoma is a benign tumor located on the vestibular nerve. Patient could present dizziness symptoms cause to the tumor, and at least after the treatment by gamaknife radiosurgery or microsurgery resection.
- Trial name
- EVTSVCGEC (NCT03670589)
- Testing
- Radiosurgery gammaknife, Microsurgery resection
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Grenoble
Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7, Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
This phase II trial studies how well chemotherapy before surgery and radiation therapy works compared to surgery and radiation therapy alone in treating patients with nasal and paranasal sinus cancer that can be removed by…
- Trial name
- NCT03493425
- Testing
- Carboplatin, Cisplatin, Docetaxel
- Where
- 154 sites in United States
- Volunteers
- 82 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Melanin Hyperpigmentation
Vitamin C Depigmenattion Versus Conventional Technique
Although physiologic gingival hyperpigmentation is not a pathologic condition, it is considered one of the main esthetic problems in dentistry.
- Trial name
- NCT03719274
- Testing
- vitamin c depigementation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Avulsion Fracture
Early Rehabilitationin in Tibial Spine Avulsion Fracture Managed With Arthoscopic Fibre Wire Fixation
Tibial spine avulsion fracture is a common knee injury in adolescents and young adults, often caused by sports trauma or falls. It involves avulsion of the anterior cruciate ligament (ACL) attachment from the tibial eminence and…
- Trial name
- ER-TSAV (NCT07428291)
- Testing
- Early Postoperative Rehabilitation Program, Conventional (Delayed) Rehabilitation Program
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Abdul Jabbar
Liver Cancer
Sorafenib Tosylate in Treating Patients With Liver Cancer That Can Be Removed by Surgery
RATIONALE: Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT01182272
- Testing
- sorafenib tosylate, laboratory biomarker analysis, neoadjuvant therapy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Anaplastic Astrocytoma, Glioblastoma
Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma
This phase II/III trial studies how well vocimagene amiretrorepvec (Toca 511) and extended release flucytosine (Toca FC) work when added to the usual treatment (temozolomide and radiation therapy) in treating patients with newly…
- Conditions
- Anaplastic Astrocytoma, Glioblastoma, Oligodendroglioma, Supratentorial Glioblastoma
- Trial name
- NCT04105374
- Testing
- Extended Release Flucytosine, NovoTTF-100A Device, Quality-of-Life Assessment
- Sponsor
- NRG Oncology
Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
This randomized phase III trial studies chemoembolization and sorafenib tosylate to see how well they work compared with chemoembolization alone in treating patients with liver cancer that cannot be removed by surgery.
- Trial name
- NCT01004978
- Testing
- Cisplatin, Computed Tomography, Doxorubicin Hydrochloride
- Where
- 281 sites in United States
- Volunteers
- 235 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Radiation Therapy During and After Lumpectomy in Treating Women With Stage I or Stage II Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy during and after surgery may kill any tumor cells that remain after surgery.
- Trial name
- NCT00647582
- Testing
- adjuvant therapy, therapeutic conventional surgery, intraoperative radiation therapy
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Gastric Cancer
"Mechanisms and Biomarkers of Response and Resistance to Current Targeted Therapies in Gastric Cancer" (THERRES)
The main aim was to assess the tumor vascular perfusion pattern in gastric cancer (GC). The investigators used dynamic contrast harmonic imaging endoscopic ultrasound (CHI-EUS) and the results were compared with the…
- Trial name
- THERRES (NCT05051423)
- Testing
- Endoscopic ultrasound
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Infertility, Anesthesia
The Effect of Music Therapy on Glutathione Peroxidase, Malondialdehyde and Pain in Oocyt Pick Up Patients.
It is used by music therapists to help the social, physical, emotional, psychological and psychological needs of patients. In a study, music has a positive effect on pain, anxiety, depression, shortness of breath, mood, facial…
- Conditions
- Infertility, Anesthesia, Oxidative Stress, Pain, Postoperative
- Trial name
- NCT04175873
- Testing
- music
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Aortic Valve Stenosis
Transapical Transcatheter Treatment Versus Conventional Surgery in Patients With Native Aortic Valve Stenosis
This study is a randomised comparison of apical stent valve treatment versus conventional valve surgery in patients with severe aortic valve stenosis.
- Trial name
- NCT00986193
- Testing
- Transapical Aortic Valve Implantation, Conventional Aortic Valve Surgery
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital Skejby
Lung Edema, Hip Fractures
Ultrasound in Evaluation of Preoperative Fluid Management of Hip Fracture Surgery Patients
Goal directed fluid therapy is a new standard surgical procedure which is successful in patients undergoing hip revision arthroplasty, There has been a reduction of postoperative complications, most importantly surgery with a…
- Trial name
- NCT05916599
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Complications, Fluid Overload
Goal-directed Intraoperative Fluid Therapy in High-risk Surgery
This study is aim to assess the effect of goal-directed intraoperative fluid therapy on patient's postoperative incidence rates of complications, length of hospitalization and hospitalization cost.
- Trial name
- NCT02470221
- Testing
- Applying goal-directed fluid therapy by continuous hemodynamic monitoring system, Conventional fluid therapy
- Volunteers
- 600 people
- Sponsor
- Huang YuGuang
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