Clinical trials: sponsored by Aalborg University Hospital
Brain Metastases, Bone Metastases
Dual Energy CT - a Tool for Delineation of Tumor and Organs at Risk in Radiotherapy
The primary aim of this clinical study, 'Dual Energy CT - a tool for delineation of tumor and organs at risk in radiotherapy' (DART) is to evaluate whether dual-energy CT (DECT) is at least as effective as magnetic resonance…
- Conditions
- Brain Metastases, Bone Metastases, Head and Neck Cancer, Lung Cancer
- Trial name
- DART (NCT07185958)
- Testing
- Dual-energy CT (DECT), Iodine-based contrast agent, Magnetic Resonance Imaging (MRI)
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Depression, Bipolar
Lithium Versus Cariprazine in the Acute Phase Treatment of Bipolar Depression (DUAG9)
The goal is to study the effect of lithium compared to cariprazine in patients with depression in a bipolar disease. The main question it aims to answer is: Difference in change between the two groups from baseline to after 8…
- Trial name
- DUAG9 (NCT05913947)
- Testing
- Lithium, Cariprazine
- Where
- Denmark
- Volunteers
- 122 people
- Sponsor
- Aalborg University Hospital
Respiratory Inflammation
Exploring Biomarkers in the Heat and Moisture Exchange Filters
When patients undergo major surgery, they are connected to a ventilator during anesthesia. A heat and moisture exchange filter (HME filter) is routinely placed in the ventilator tubing to ensure that the inhaled air is warm and…
- Trial name
- HMEPRO (NCT07607977)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aalborg University Hospital
Type 2 Diabetes, Osteoporosis
Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes
The DIACTIVE study is a randomized controlled trial with a 5- year follow-up designed to evaluate the impact of comprehensive screening and multicomponent interventions on fall prevention, bone health, nerve function and…
- Conditions
- Type 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall Prevention
- Trial name
- DiaACTIVE (NCT06745544)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Maxillary Transverse Deficiency
Tooth-Borne (TBA) Versus Hybrid Expanders (HA) in Surgically Assisted Rapid Maxillary Expansion (SARME)
This randomized clinical trial will compare two types of expansion appliances used with surgically assisted rapid maxillary expansion (SARME) in adults with a narrow upper jaw.
- Trial name
- SARME-TBA/HA (NCT07849855)
- Testing
- Tooth-Borne Maxillary Expansion Appliance, Hybrid Tooth-Bone-Borne Maxillary Expansion Appliance
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 32 people
- Sponsor
- Aalborg University Hospital
Third Molars Extraction
Avatar-assisted Pre- and Post-operative Information Following Surgical Removal of a Mandibular Third Molar.
This study assess the efficacy of digital avatar-assisted pre- and post-operative information against nurse-led oral and written information following SRM3 including an analysis of potential risk factors associated with impaired…
- Trial name
- NCT07805304
- Testing
- Avatar-assisted pre- and post-operative information following surgical removal of an mandibular third molar
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Aortic Stenosis, Heart Failure
Quality of Life After Transcatheter Aortic Valve Implantation
This observational cohort study investigates whether hemodynamic improvements following transcatheter aortic valve implantation (TAVI) are associated with improvements in patient-reported quality of life among patients in Western…
- Conditions
- Aortic Stenosis, Heart Failure, Angina Pectoris, TAVI(Transcatheter Aortic Valve Implantation)
- Trial name
- TAVI-QoL (NCT07798713)
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Benign Paroxysmal Positional Vertigo (BPPV)
Comparison of Two Mechanical Rotation Chairs With Diagnostics of Benign Paroxysmal Positional Vertigo.
This study aims to investigate whether the diagnosis of benign paroxysmal positional vertigo (BPPV) is equally good with two different mechanical rotation chairs (MRCs) (TRV rotary chair and the Rotundum rotary chair).
- Trial name
- ROTATE (NCT07772973)
- Testing
- TRV® (Interacoustics©, Middelfart, Denmark), mechanical rotational chair, Rotundum® (balcare GmbH©, Küsnacht, Switzerland), mechanical rotational chair.
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Coronary Arterial Disease (CAD), Ischemic Heart Disease (IHD)
Revascularization of Calcified Coronary Arteries
The primary aim of this study is to evaluate changes in absolute coronary flow and pressure before and after percutaneous coronary intervention in calcified lesions.
- Conditions
- Coronary Arterial Disease (CAD), Ischemic Heart Disease (IHD), Percutaneous Coronary Intervention (PCI)
- Trial name
- PICA (NCT07724184)
- Testing
- Measurement of coronary flow and pressure
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aalborg University Hospital
Infertility
Food Intake Among Women and Men in Fertility Treatment
Worldwide infertility is highly prevalent and lifestyle factors, such as food intake, could have an essential role in the success of a fertility treatment.
- Trial name
- Food&Fertility (NCT05454046)
- Testing
- Food intake among women and men in fertility treatment
- Where
- 8 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Aalborg University Hospital
Ovarian Cancer
[68Ga]Ga-FAPI-46 PET/CT in Ovarian Cancer
Fifty (n=50) patients with newly diagnosed ovarian cancer will undergo FAPI PET/CTs in addition to routine diagnostic workup (including FDG PET/CT) at primary staging and restaging.
- Trial name
- NCT05903807
- Testing
- 68Ga-FAPi-46
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Low Anterior Resection Syndrome, Faecal Incontinence With Faecal Urgency
Understanding and Tailored Treatment of Low Anterior Resection Syndrome
The goal of this observational study is to learn why some patients develop low anterior resection syndrome (LARS) after colorectal cancer treatment.
- Conditions
- Low Anterior Resection Syndrome, Faecal Incontinence With Faecal Urgency, Faecal Incontinence, Colorectal (Colon or Rectal) Cancer Survivors
- Trial name
- PATO-LARS (NCT07573371)
- Where
- 3 sites in Denmark
- Volunteers
- 145 people
- Sponsor
- Aalborg University Hospital
Treatment Resistant Depression (TRD)
Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression
The trial utilizes a pragmatic, randomized, open label design with two parallel arms. Participants aged 18-65 with a diagnosis of unipolar depressive disorder and without stable remission in the past 12 months are randomized 1:1…
- Trial name
- NCT07080723
- Testing
- Algorithm guided treatment (AGT), Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Mental Health Help-Seeking, Mental Health Difficulties
Changes in Children and Young People's Well-being and Parental Stress While Seeking Help at CAMHS in Denmark. How Does Waiting Affect CYP and Their Parents Before, During and After CAMHS Assessments.
Questionnaire-based longitudinal cohort study. Families on the waiting list for an assessment with Child and Adolescent Mental Health Services (CAMHS) are invited to complete questionnaires including the Parental Stress Scale…
- Conditions
- Mental Health Help-Seeking, Mental Health Difficulties, Help-Seeking Behavior, Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes
- Trial name
- NCT07553104
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Diabetes Mellitus, Type 2
The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin
The objective of the trial is to investigate the effect of adherence to oral semaglutide dosing instructions on glycaemic control in people with type 2 diabetes, which are dysregulated on metformin and naïve to second line…
- Trial name
- DIACRON (NCT06333080)
- Where
- Denmark
- Volunteers
- 1 people
- Sponsor
- Aalborg University Hospital
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Urinary Incontinence, Daytime Wetting
The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.
The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI)…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urologic Diseases
- Trial name
- NCT07535619
- Where
- 4 sites in Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Thyroid Disease, Hashimoto's Thyroiditis
ThyMoves: Screening and Exercise to Improve Muscle, Enhance Quality of Life, and Reduce Fall Risk in Thyroid Disease
Objectives: This study aims to assess health-related quality of life (QoL) in adults with thyroid hormone disorders and identify modifiable factors to improve QoL in patients with Hashimoto's thyroiditis (HT) and multinodular…
- Conditions
- Thyroid Disease, Hashimoto's Thyroiditis, Hyperthyreosis and Goiter, Hypothyroidism
- Trial name
- ThyMoves (NCT06960005)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 148 people
- Sponsor
- Aalborg University Hospital
Orthognathic Surgery
Dietary Interventions to Reduce Postoperative Weight Loss and Improve Recovery After Orthognathic Surgery
Objectives This randomized controlled trial aimed to assess whether structured dietary interventions, implemented both before and after orthognathic surgery, could minimize postoperative weight loss and thereby enhance recovery…
- Trial name
- NCT07431268
- Testing
- Intervention group receiving nutritional supplements through G-tube and Protein drinks, Intervention group receiving nutritional supplements through Protein drinks
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aalborg University Hospital
Type 2 Diabetes Treated With Insulin
The Intelligent Diabetes TelemonitoRing Using Decision Support to Treat Patients on Insulin Therapy
The trial is an open-label, randomized controlled trial. Patients with T2D on insulin therapy will be randomized to an intelligent telemonitoring group (intervention), a telemonitoring group (control), and a usual care group…
- Trial name
- DiaTRUST (NCT06185296)
- Testing
- Intelligent telemonitoring, Telemonitoring
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- Aalborg University Hospital