Clinical trials: sponsored by Aalborg University Hospital
Robotic Cardiac Surgery Simulation
Robotic Cardiac Surgery Wet Lab Simulation Study
The goal of this study is to investigate validity of the wet lab robotic cardiac surgery model used for training in robotic cardiac surgery and to evaluate learning curves in trainees of different surgical specialities.
- Trial name
- NCT05043064
- Testing
- Wet lab tasks
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Urethral Stricture, Urethral Stricture, Anterior
Treatment of Bulbar Urethral Strictures With Optilume Drug-Coated Balloons in an Untreated Population
This randomized controlled trial investigates the effectiveness and safety of the Optilume® drug-coated balloon (DCB) compared to standard direct visual internal urethrotomy (DVIU) in the treatment of bulbar urethral strictures.
- Conditions
- Urethral Stricture, Urethral Stricture, Anterior, Urethral Stricture, Male, Urethral Stricture Less Than 2 cm
- Trial name
- FIRST-CARE (NCT06827210)
- Testing
- Optilume DCB, Standard Direct Visual Internal Urethrotomy (DVIU)
- Where
- 3 sites in Denmark
- Volunteers
- 140 people
- Sponsor
- Aalborg University Hospital
Head and Neck Squamous Cell Carcinoma
Specific Methylation Profiles in HNSCC
In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas.
- Trial name
- NCT04567056
- Testing
- Blood sample
- Where
- Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Small Cell Lung Cancer
Proteomics in Small Cell Lung Cancer
The aim of this study is to gather insight into tumor-derived circulating extracellular vesicles-proteins in patients with newly diagnosed small cell lung cancer.
- Trial name
- SCLC-OMICS (NCT05623956)
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Amyotrophic Lateral Sclerosis, Pseudobulbar Affect
Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect
The investigators aim to elucidate characteristics of structural and functional brain connectivity in patients with amyotrophic lateral sclerosis (ALS) and pseudobulbar affect (PBA) using diffusion kurtosis imaging (DKI) and…
- Trial name
- NCT06396260
- Testing
- Diffusion Kurtosis Imaging (DKI), Resting State Magnetoencephalography
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Radiation-induced Diarrhoea in Prostate and Rectal Cancer
Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer
Approx. 80% of patients with prostate and rectal cancer who receive radiation therapy (RT) experience acute radiation-induced diarrhea (RID).
- Trial name
- PRECANU (NCT05684432)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Pulmonary Embolism
Non-invasive Diagnosis of Pulmonary Embolism by Use of Biomarkers in Exhaled Breath
In this study, a new, non-invasive method for diagnosis of pulmonary embolism (PE) will be tested. In pre-clinical studies, the investigators have identified 151 putative biomarkers for pulmonary embolism in the exhaled breath…
- Trial name
- NILEX (NCT06135220)
- Testing
- New method for diagnosis of pulmonary embolism (PE) in order to validate/consolidate 151 putative identified biomarkers for PE in the exhaled breath.
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Telerehabilitation, COPD
Long-term Home-based Exercise for Patients With COPD: the COPDtoParis Project
This randomised controlled trial (RCT) aims to investigate the effect of long-term, interactive home-based cycle-exercise on patients with Chronic Obstructive Pulmonary Disease (COPD) after a COPD exacerbation requiring…
- Conditions
- Telerehabilitation, COPD, Quality of Life, Mobility Limitation
- Trial name
- COPDtoParis (NCT06235502)
- Testing
- Home-based cycle-exercise for COPD patients, Standard of Care
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Colon Disease
A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy
The trial is about comparing the efficacy of Plenvu with Picoprep. Both are bowel cleansing agents prior to visual examination of the large bowel to exclude cancer disease.
- Trial name
- NCT05436054
- Testing
- Picoprep, Plenvu
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aalborg University Hospital
Macular Edema, Non-infectious Uveitis
Incidence of Macular Edema in a Uveitis Population
Macular edema from uveitis is a serious condition that can lead to vision loss. Uveitis is an inflammation inside the eye, and macular edema is when fluid builds up in the central part of the retina, called the macula, which is…
- Trial name
- NCT06686641
- Testing
- Local and systemical treatment
- Where
- Denmark
- Volunteers
- 1,550 people
- Sponsor
- Aalborg University Hospital
Pancreatogenic Type 3C Diabetes Mellitus
Effect of Continuous Glucose Monitoring on Hypoglycemia in Adults With Pancreatogenic Diabetes
This study will investigate the effect of continuous glucose monitoring (CGM) (compared to self-monitoring) on hypoglycemia and glycemic control in patients with insulin-treated pancreatogenic diabetes.
- Trial name
- NCT05550480
- Testing
- Continuous glucose monitoring
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aalborg University Hospital
Eating Disorders
Prevalence of Eating Disorder Symptomatology Among Outpatients Referred to Health Promotion from Somatic Hospital Departments
The Department of Health Promotion at Aalborg University Hospital gets patients referred from all the hospital's departments. The Department of Health Promotion offers lifestyle courses to aid preventing disease relapses and…
- Trial name
- NCT05656859
- Testing
- Single group
- Where
- Denmark
- Volunteers
- 136 people
- Sponsor
- Aalborg University Hospital
Atrial Fibrillation, Heart Failure
Danish Evaluation of Early Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure
The DanAblate-HF trial will investigate whether early catheter ablation treatment for atrial fibrillation in patients with heart failure is superior to standard treatment.
- Trial name
- DanAblate-HF (NCT06560047)
- Testing
- Catheter ablation
- Where
- 6 sites in Denmark
- Volunteers
- 1,616 people
- Sponsor
- Aalborg University Hospital
Low Back Pain
Education of Municipality-based Physiotherapists in Managing Disabling Low Back Pain - an Observational Study
A consistent theme in the modern-day healthcare system is the difficulty of transferring research knowledge into clinical practice.
- Trial name
- NCT05794373
- Testing
- Standard physiotherapy for low back pain in a municipality setting
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Diabetic Peripheral Neuropathy, Diabetes
Diabetes, Falls, and Fractures
Comparing severity of diabetic peripheral neuropathy (small and large fibers including autonomic neuroapthy) to postural control and vestibular measurements
- Conditions
- Diabetic Peripheral Neuropathy, Diabetes, Balance; Distorted, Vestibular Neuropathy
- Trial name
- DIAFALL (NCT05389566)
- Testing
- Quantative Sensory Testing, NCStat-DPN-Check, Composite Autonomic Symptom Score 31
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Diabetes, Diabetes Mellitus, Type 1
Comparison of Histamine and Local Heating for Evoking the Axon-reflex Flare Response in Diabetes
Diabetic peripheral neuropathy is the most common complication to diabetes mellitus affecting as much as 50% of the population with diabetes.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetic Neuropathy Peripheral, Small Fiber Neuropathy
- Trial name
- HistaHeat (NCT05921097)
- Testing
- Histamin-induced axon-reflex flare response, Local heating-induced axon-reflex flare response, 2-point discrimination tasks
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Catheter-Related Infections, Catheter Related Complication
Comparison of Two Peripheral Inserted Intravenous Catheters
Central venous catheters are routinely used, however, with a complication rate exceeding 15%. Therefore, other types of venous catheters have been introduced such as a midline catheter.
- Trial name
- NCT04140916
- Testing
- Midline catheter, PICC-line catheter
- Where
- Denmark
- Volunteers
- 304 people
- Sponsor
- Aalborg University Hospital
Hypoxemic Respiratory Failure, Oxygen Toxicity
Handling Oxygenation Targets in COVID-19
Patients with COVID-19 and hypoxaemic respiratory failure and admitted to the intensive care unit (ICU) are treated with supplementary oxygen as a standard. However, quality of quantity evidence regarding this practise is low.
- Trial name
- HOT-COVID (NCT04425031)
- Testing
- Low oxygenation target, High oxygenation target
- Where
- 10 sites in Denmark, Norway and 1 more
- Volunteers
- 726 people
- Sponsor
- Aalborg University Hospital
Crohn Disease
The Innate Immune Response and Enteric Nervous System in Crohn's Disease.
The study aims to explore the relationships between inflammation, nerve changes, and the expression of interferon-stimulated proteins in inflamed and non-inflamed bowel areas from patients with Crohn's disease.
- Trial name
- NCT06485193
- Testing
- Immunohistochemistry
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Aalborg University Hospital
Neuropathy, Diabetic, Small Nerve Fiber Neuropathy
Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy
Predicting early onset neuropathy in people with type 1 diabetes
- Conditions
- Neuropathy, Diabetic, Small Nerve Fiber Neuropathy, Type 1 Diabetes
- Trial name
- NeuroPredict (NCT05546138)
- Testing
- Skin biopsies with quantification of intra-epidermal nerve fibre density, Perception Threshold Tracking, Thermal perception thresholds
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital