Clinical trials: sponsored by Aarhus University Hospital
Head and Neck Neoplasms
Remote Ischemic Preconditioning in Head and Neck Cancer Reconstruction - A Randomized Controlled Trial
The purpose of the trial is to investigate, if remote ischemic preconditioning reduces the risk of complications in patients undergoing resection of head and neck cancer and immediate reconstruction with autologous free tissue…
- Trial name
- RIPC-HNC (NCT02548377)
- Testing
- Remote ischemic preconditioning
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital Skejby
Fragility
Geriatrician-performed Comprehensive Geriatric Care in an Outpatient Community Rehabilitation Unit
Introduction: Older adults with multiple illnesses represent the fastest growing sector of society and make increasing demands on all sectors of the health care system, particularly in outpatient community rehabilitation units…
- Trial name
- GCGCCRU (NCT01506219)
- Testing
- Geriatrician-performed CGC
- Where
- 2 sites in Denmark
- Volunteers
- 368 people
- Sponsor
- Aarhus University Hospital
Breast Cancer
Metformin in Breast Cancer, Visualized With Positron Emission Tomography
The general purpose of the trial is to investigate whether metformin is taken up into the breast tumor. Studies in the last few years have shown an effect of metformin on cell proliferation on breast cancer.
- Trial name
- NCT02882581
- Testing
- 11C-metformin
- Where
- 2 sites in Denmark
- Volunteers
- 7 people
- Sponsor
- Aarhus University Hospital
Cancer
Dual Energy CT: A New Method for Better Dose Calculation in Proton Beam Therapy
Researchers want to compare proton stopping ratios, used for proton beam therapy planning, calculated based on single energy CT and dual energy CT images; with the intension of improve upon the proton range determination.
- Trial name
- (DUAL) (NCT02722109)
- Testing
- No intervention
- Volunteers
- 14 people
- Sponsor
- Aarhus University Hospital
Diabetes Mellitus, Type 2, Diabetes Complications
Arterial Stiffness and Complication Risk in Type 2 Diabetes
Background The prevalence and incidence of type 2 diabetes is increasing globally. A common complication of diabetes is the disease of the blood vessels, vascular diseases, which can cause disorders like myocardial infarction…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Complications, Diabetic Angiopathies, Diabetic Nephropathies
- Trial name
- NCT02001532
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Ulcerative Colitis
Amino Acids in Ileal Pouch-anal Anastomosis for Ulcerative Colitis
The detrimental effects of catabolism, insuline resistance and muscle wasting on surgical outcome is wellknown. This catabolism is especially pronounced in patients with acute or chronic inflammation (IBD, cancer) and for those…
- Trial name
- AMINOPOUCH (NCT02084550)
- Testing
- Vaminolac, Saline
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Aarhus University Hospital
Abdominal Obesity, Metabolic Syndrome
The Effect of Whey Protein and Dietary Fibers on Risk Markers of the Metabolic Syndrome and Bone Health
The prevalence of overweight and lifestyle related diseases such as cardiovascular disease (CVD) and type 2 diabetes (T2D) is increasing world wide.
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- MERITS (NCT02931630)
- Testing
- Whey protein powder, Maltodextrin powder, High fiber bread
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Obese
The Effect of Vitamin B3 on Substrate Metabolism, Insulin Sensitivity, and Body Composition in Obese Men
In animals, treatment with vitamin B3 improved insulin sensitivity and substrate metabolism. It is currently not know if vitamin B3 has the same positive effects in humans.
- Trial name
- NCT02303483
- Testing
- Nicotinamide riboside (NIAGEN TM, ChromaDex, CA, USA )
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Aortic Valve Stenosis
Transapical Transcatheter Treatment Versus Conventional Surgery in Patients With Native Aortic Valve Stenosis
This study is a randomised comparison of apical stent valve treatment versus conventional valve surgery in patients with severe aortic valve stenosis.
- Trial name
- NCT00986193
- Testing
- Transapical Aortic Valve Implantation, Conventional Aortic Valve Surgery
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Disease
Randomized Comparison of ExoSeal® and Angio-Seal Vascular Closure Devices: The CLOSE-UP II Trial
Is the ExoSeal VSD non-inferior to Angio-Seal vascular closure device (VSD) in the incidence of adverse access site related events at 30 days.
- Trial name
- CLOSE-UP II (NCT02234830)
- Testing
- Exoseal closure device, Angioseal closure device
- Where
- 2 sites in Denmark
- Volunteers
- 818 people
- Sponsor
- Aarhus University Hospital Skejby
Prematurity, Respiratory Distress Syndrome, Infant
Weaning of Nasal Continuous Positive Airway Pressure (CPAP) in Premature Infants
The aim of this study is to investigate two different strategies for the withdrawal of CPAP in preterm infants born before 32 weeks of gestation.
- Trial name
- NCT01721629
- Testing
- Sudden wean of nasal CPAP, Gradual wean of nasal CPAP
- Where
- 6 sites in Denmark
- Volunteers
- 380 people
- Sponsor
- Aarhus University Hospital
Coronary Artery Disease, Ischemic Heart Disease
Everolimus-eluting SYNERGY Stent Versus Biolimus-eluting Biomatrix NeoFlex Stent - SORT-OUT VIII
The purpose of this study is to perform a randomised comparison between the SYNERGY and the Biomatrix NeoFlex stents in treatment of unselected patients with ischemic heart disease.
- Trial name
- SORT-OUT VIII (NCT02093845)
- Testing
- Biomatrix NeoFlex coronary stent, SYNERGY stent
- Where
- 3 sites in Denmark
- Volunteers
- 2,800 people
- Sponsor
- Aarhus University Hospital Skejby
Obesity, Metabolic; Complications
Effect of Carbonated Soft Drinks on the Body Weight
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks…
- Conditions
- Obesity, Metabolic; Complications, Dietary Habits
- Trial name
- NCT00777647
- Testing
- Sugar-sweetened soft drink, Aspartame-sweetened soft drink, Semi-skimmed milk
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Prostate Cancer
MRI in Active Surveillance of Prostate Cancer
The purpose of this study is to investigate the hypothesis, that mMRI provides a more accurate and secure interpretation of the aggressiveness of prostate cancer initially/before mMRI defined as low risk.
- Trial name
- NCT02326246
- Testing
- multi-parametic MRI
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Aarhus University Hospital Skejby
Developmental Dysplasia of the Hip
Outcome After Arthroscopic Surgery in Patients Treated With PAO
The purpose of the study is to evaluate outcome after arthroscopy if the hip in patients previous treated with periacetabular osteotomy
- Trial name
- NCT02945995
- Testing
- hip arthroscopy
- Volunteers
- 45 people
- Sponsor
- Aarhus University Hospital
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Magnetic Resonance Diagnostics of Diabetic Peripheral Neuropathy
This project aims to develop high field MR techniques to detect nerve lesions in diabetic patients. The MRI findings will be compared to results from conventional evaluations and nerve conduction studies to determine the validity…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy, Hereditary Axonal Neuropathy
- Trial name
- NCT01847937
- Where
- 5 sites in Denmark, Germany
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Geriatric Disorder
Assessment of Functional Ability and Follow-up at Home for Older Medical Patients
The aim of this study is to examine the effect of an intervention that consist of assessment of functional ability, rehabilitation plan and follow-up at home for older medical patients.
- Trial name
- NCT02078466
- Testing
- Assessment of functional ability and follow-up at home
- Where
- Denmark
- Volunteers
- 380 people
- Sponsor
- Aarhus University Hospital
Hypertension
Renal Sympathectomy in Treatment Resistant Essential Hypertension, a Sham Controlled Randomized Trial
The purpose of this double blind, randomized and sham controlled study is to determine whether renal denervation in terms of catheter based ablation in the renal arteries is effective in lowering blood pressure in patients with…
- Trial name
- ReSET (NCT01459900)
- Testing
- Renal artery ablation, Renal angiography
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Aarhus University Hospital Skejby
Radial Angiography
Randomized Comparison of Sheaths for Radial Access
Coronary angiography (CAG) and possible angioplasty (Percutaneous Coronary Intervention = PCI) can be performed by access from the groin (a. femoralis), the wrist (a. radialis) or the elbow (a. brachialis).
- Trial name
- ACCESS-I (NCT02637843)
- Testing
- Slender Sheath
- Where
- Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Fuchs' Endothelial Corneal Dystrophy
Fuchs' Endothelial Dystrophy: Clinical Characteristics, Treatment Outcome, and Pathology
Background Fuchs' Endothelial Dystrophy Fuchs' Endothelial Dystrophy (Fuchs' ED) is characterized by changes on the inside of the cornea, which leads to a substantial decline in visual acuity.
- Trial name
- NCT01979250
- Testing
- DSAEK surgery
- Where
- Denmark
- Volunteers
- 81 people
- Sponsor
- Aarhus University Hospital