Clinical trials: sponsored by Aarhus University Hospital
Nonshivering Thermogenisis
Human Neck Brown Adipose Tissue mRNA Profile, a Seasonal Variation Study.
The primary objective in this study is to examine the seasonal variation in genetic markers in the deep neck adipose tissue in humans.
- Trial name
- NCT02486419
- Testing
- Outdoor weather
- Where
- Denmark
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Pain
Kryptonite - a Novel Osteosynthesis Method for Median Sternotomy
The aim of this study was to investigate the beneficial effect of bone cement in combination with wire cerclage on the stability of the sternum following median sternotomy.
- Trial name
- NCT02738437
- Testing
- Kryptonite-bone cement
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Aarhus University Hospital
Heart Transplant Recipients
The GRAFT Study: Evaluation of Graft Function, Rejection and Cardiac Allograft Vasculopathy in First Heart Transplant Recipients.
Objective: To assess the relationship between coronary allograft vasculopathy (CAV) and graft function, and to evaluate non-invasive methods for CAV diagnosis.
- Trial name
- NCT02077764
- Testing
- OCT and coronary angiography, Right heart cat., PET
- Where
- Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Spina Bifida
Incidence of Pregnancies and Births With Spina Bifida in Denmark in 2008-2014
Neural tube defects cover a group of severe embryo malformations such as anencephaly and spina bifida. The most severe forms of spina bifida causes numerous disabilities that demand lifelong treatment by a team consisting of…
- Trial name
- NCT02685813
- Where
- Denmark
- Volunteers
- 350,000 people
- Sponsor
- Aarhus University Hospital
Leukemia
Pharmacokinetics of Asparaginase and Antibody Formation in Interfant-06
Asparaginase is an important drug in the treatment of childhood leukemia including in infant (<1 year). The prognosis for infants is bad.
- Trial name
- NCT01025804
- Where
- 6 sites in Denmark, Finland and 3 more
- Volunteers
- 15 people
- Sponsor
- Aarhus University Hospital
Chronic Pain
Investigation of the Pain Relieving Properties of Lipotransplantation After Treatment for Breast Cancer
Background In Denmark, breast cancer is the most common fatal cancer in women with more than 4700 new cases annually. Unfortunately, up to 60% of women who are treated surgically for breast cancer, will experience chronic pain as…
- Trial name
- NCT01888419
- Testing
- Lipotransplantation
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Aarhus University Hospital
Under Nutrition
The Effect of Nutrition Follow up After Hospital Discharge in Undernourished Elderly
The purpose of this study is to test two different interventions of nutrition follow up after discharge from geriatric ward in undernourished geriatric patients.
- Trial name
- NCT01345032
- Testing
- Home visit, Telephone consultation
- Where
- 2 sites in Denmark
- Volunteers
- 208 people
- Sponsor
- Aarhus University Hospital
Narrow Band Imaging and PDD in Cystoscopy
Comparison of White Light, PDD and NBI in Detection of Flat Dysplasia and CIS at TURB - a Study of Trimodality
All patients planned for PDD guided TURB can be included in this study. Two different optics with PDD and NBI are applied to the resectoscope in addition to regular WL.
- Trial name
- DaBlaCa-8 (NCT02313662)
- Testing
- NBI and PDD
- Where
- 4 sites in Denmark, Norway
- Volunteers
- 153 people
- Sponsor
- Aarhus University Hospital
Hearing Loss - Conductive
Stability of the Cochlear Baha BI300/BA400 Implant System Loaded From 1 Week Post-surgery
Objectives To evaluate the safety of processor loading of the Cochlear BI300/BA400 implant system 1 week after implantation To evaluate the short term soft tissue healing and the long term skin reaction, with the new Cochlear…
- Trial name
- NCT02096809
- Testing
- One week loading of Bone Anchored Hearing Aid (BAHA), Cochlear Baha BI300/BA400 Implant System
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Aarhus University Hospital
Heart Disease, Pleural Effusion
Pleural and Pericardial Effusion Following Open Heart Surgery
One of the most common postoperative complications after open cardiac surgery is fluid accumulation between the pleural membranes or in the pericardial sac.
- Conditions
- Heart Disease, Pleural Effusion, Pericardial Effusion
- Trial name
- IMAGING (NCT02045641)
- Testing
- pleuracentesis
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- Aarhus University Hospital Skejby
Aortic Stenosis
Myocardial Efficiency of the Left Ventricle in Asymptomatic Patients With Aortic Valve Stenosis - a Prognostic Marker and a Target for Intervention?
Background - Aortic valve stenosis (AS) is the most common heart valve disease among adults in the Western world with a prevalence of 3 % in people older than 75 years of age.
- Trial name
- MELVAS (NCT02076711)
- Testing
- Metoprololsuccinate
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aarhus University Hospital
Femoral Neck Fracture
Dynaloc for Treatment of Femoral Neck Fractures
A prospective, randomized study comparing the effectiveness of a new system, Dynaloc compared with three cancellous screws, for osteosynthesis of femoral neck fractures
- Trial name
- NCT02030431
- Testing
- Dynaloc, Cancellous screws
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aarhus University Hospital
Parkinson´s Disease
Common Noradrenergic Mechanisms in Parkinson´s Disease and L-DOPA Induced Dyskinesia
The aims of this proposal include tests of hypotheses of the pathogenetic mechanisms of noradrenergic neurotransmission in Parkinson's disease in vivo, using positron emission tomography of patients with early and advanced…
- Trial name
- NORAPARK (NCT02578849)
- Testing
- L-DOPA
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Magnetic Resonance
Test-retest Stability of MR-parameters. A Neuroimaging Pilot-study in Healthy Volunteers
Aim: To study the stability of brain MR-scanning parameters (blood-flow, microstructure, volume, metabolism) over 1 week in health volunteers. Hypothesis: MR-scanning parameters are stable over 1 week in healthy volunteers
- Trial name
- NCT01239615
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Coronary Disease
The Does Optical Coherence Tomography Optimize Revascularization (DOCTOR) Recross Study
Prospective, controlled, double randomized, non-blinded, multicenter, investigator initiated, academic superiority trial comparing optical coherence tomography (OCT) guided vs.
- Trial name
- DOCTOR Recross (NCT02234804)
- Testing
- Xience Prime Stent, Medtronic Resolute Integrity stent, Angiography
- Where
- 3 sites in Belgium, Denmark and 1 more
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital Skejby
Ischaemic Heart Disease, Aortic Stenosis
Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.
To evaluate the effect on cognitive function, recovery, cardioprotection and haemodynamics of standard Remifentanil anaesthesia to standard Sufentanil anaesthesia in patients undergoing coronary artery bypass with or without…
- Trial name
- PRECON2 (NCT02053818)
- Testing
- Remifentanil, Sufentanil
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Rectal Prolapse
Laparoscopic Rectopexy for Rectal Prolapse
The aim of the present prospective, double-blind, randomized study is to study whether laparoscopic anterior mesh rectopexy is as good as laparoscopic posterior rectopexy with respect to obstructive defecation afterwards.
- Trial name
- NCT00946205
- Testing
- Laparoscopic posterior rectopexy, Laparoscopic anterior mesh rectopexy
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Aarhus University Hospital
Sepsis, Septic Shock
Piperacillin Pharmacokinetics in ICU Patients
Antibiotic dosing in critically ill patients poses a challenge for clinicians due to the pharmacokinetic changes seen in this population.
- Trial name
- NCT02478073
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital
Coronary Heart Disease, Heart Failure
Efficacy of Physical Exercise in Cardiac Rehabilitation
Physical rehabilitation is a key element in the treatment of patients with cardiovascular diseases, and recent evidence has shown that supervised exercise programmes can prevent cardiovascular events, improve physical function…
- Conditions
- Coronary Heart Disease, Heart Failure, Ischemic Heart Diseases
- Trial name
- NCT01617850
- Testing
- Supervised physical exercise training x3 weekly for 12 weeks, Supervised physical exercise training x2 weekly for 8 weeks
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aarhus University Hospital Skejby
Disorder of Cardiac Function
Conventional vs Ultrasound Guided Arteria Cannulation.
The aim of the project is to compare two methods for arterial cannulation. The traditional method with ultrasound guided cannulation. The investigators goal is to improve this procedure to reduce pain and complications.
- Trial name
- NCT01690416
- Testing
- Traditional palpation technique, Ultrasound DNTP
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aarhus University Hospital Skejby