Clinical trials: sponsored by Aarhus University Hospital
Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders
i-CBT Functional Gastrointestinal Disorders in Youth: the Impact of Negative Illness Understanding and Parental Illness Worries
The aim of the current study, embedded in The Danish FGID Treatment Study, is to test Danish versions of Swedish i-CBT programs for children and adolescents with FGID in a Danish clinical context and to further evaluate the…
- Conditions
- Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
- Trial name
- NCT05486585
- Testing
- Internet delivered cognitive behavioural therapy for functional gastrointestinal disorders
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Pain, Face
First-in-man Imaging of a New PET Radiotracer for Oxytocin Receptors
The investigators will test a new positron-emitting radiotracer to determine whether it is suitable for studying the oxytocin receptor by positron emission tomography (PET) in humans.
- Trial name
- NCT06955650
- Testing
- Imaging procedure to measure the distribution of a newly developed radiolabeled ligand for the oxytocin receptor
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Metastatic Breast Cancer, Estrogen-receptor-positive Breast Cancer
The FEMA Study: Feasibility of Exercise in Patients With Metastatic Breast Cancer and Adiposity
The goal of this clinical trial is to test a physical activity program in patients with metastatic breast cancer and overweight receiving endocrine-based treatment.
- Conditions
- Metastatic Breast Cancer, Estrogen-receptor-positive Breast Cancer, Adiposity
- Trial name
- NCT06343987
- Testing
- Physical Activity
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Aarhus University Hospital
Hiv
Early Administration of Romidepsin and 3BNC117 in Treatment-naïve HIV Patients Starting ART
To evaluate the effect of early viral reactivation by latency reversing agents (LRA) and/or administration of potent broadly neutralizing antibodies (bNAb) on the size of the latent HIV-1 reservoir in treatment naïve HIV-1…
- Trial name
- eCLEAR (NCT03041012)
- Testing
- Romidepsin, 3BNC117, Antiretrovirals
- Where
- 7 sites in Denmark, United Kingdom
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Eating Disorders, Psychiatric Disorder
Body Project SMIL: Prevention of Eating Disorders Among Young Women With Psychiatric Illness With the Body Project
The Body Project SMIL tests the effectiveness of a virtual, peer-led intervention aimed at reducing body dissatisfaction and preventing eating disorders in young women with psychiatric illnesses.
- Conditions
- Eating Disorders, Psychiatric Disorder, Body Dissatisfaction, Eating Disorder Symptom and Body Image Dissatisfaction
- Trial name
- BP_SMIL (NCT06893627)
- Testing
- Body Project, Expressive writing
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Aarhus University Hospital
Coronary Artery Disease
Influence of Lipid Lowering on Impaired Coronary Flow
This study assess in patients with stable chest pain and coronary artery disease (CAD) determined by coronary CTA whether cholesterol lowering with regression of coronary adverse plaque characteristics is associated with recovery…
- Trial name
- NCT05368545
- Testing
- High intensity lipid lowering
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Aarhus University Hospital
Chronic Fatigue, Cancer Survivors
Chrono-behavioral Therapy for Chronic Fatigue in Cancer
Cancer-related fatigue (CRF) is a severe and persistent side effect of cancer and its treatment, affecting up to 40% of patients and significantly reducing quality of life.
- Trial name
- ChronoBT (NCT06845267)
- Testing
- Chronotherapy, Control
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aarhus University Hospital
Atrial Fibrillation, Persistent
Re-ablation of Persistent Atrial Fibrillation
Pulmonary vein re-isolation plus Vein of Marshall ethanol ablation in combination with block of mitral and tricuspid isthmuses and dome line will be compared to pulmonary vein re-isolation alone in patients undergoing re-ablation…
- Trial name
- Re-AF (NCT06845085)
- Testing
- Intervention, Control
- Where
- 3 sites in Denmark, Netherlands and 1 more
- Volunteers
- 180 people
- Sponsor
- Aarhus University Hospital
Tic Disorders
Mobile App-assisted Behavioral Treatment in Children and Adolescents With Tics
Chronic tic disorders are neurodevelopmental disorders affecting 0.5-1% of children and adolescents. Tics present as sudden, rapid, repetitive non-rhythmic movements or vocalizations or a combination.
- Trial name
- NCT05390268
- Testing
- Mobile app-assisted behavioral treatment, Mobile app-assisted psychoeducation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Persistent Physical Symptoms
My Symptoms: an eHealth and GP Assisted Programme for Persistent Symptoms in Primary Care
The project 'My Symptoms' is part of a large research programme: eHealth and GP-assisted self-help interventions for persistent physical symptoms (eASY). See www.mine-symptomer.dk.
- Trial name
- eASY (NCT06163014)
- Testing
- My Symptoms eHealth programme
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Aarhus University Hospital
Chronic Tic Disorder
Treatment Outcome of Combined Virtual Tic Training in Children and Adolescents With a Chronic Tic Disorder
Tics are unwanted, repetitive movements or sounds that are either simple or complex in appearance. Tic disorders often have a huge impact on children's life.
- Trial name
- NCT04678180
- Testing
- Combined HRT and ERP
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Aarhus University Hospital
Binge-Eating Disorder, Emotion Regulation
Profiling the Dynamic of Binge Eating Disorder (PRODY-BED)
The goal of this observational study is to explore if different and specific profiles can be identified in adults with binge eating disorder (BED) depending on their additional eating pathology, emotion regulation and executive…
- Conditions
- Binge-Eating Disorder, Emotion Regulation, Executive Dysfunction, Eating Behavior
- Trial name
- PRODY-BED (NCT05726721)
- Testing
- Treatment as usual, Psychotherapy
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- Aarhus University Hospital
Breast Cancer
Preoperative Magnetic Resonance Imaging to Obtain Adequate Resection Margins in Breast Conserving Surgery, (PRIMAR) Trial
The goal of this randomised study is to investigate if a supplementary preoperative breast Magnetic Resonance Imaging (MRI) improves the assessment of breast cancer and can help surgical planning such that sufficient resection…
- Trial name
- PRIMAR (NCT05825768)
- Testing
- Breast MRI, standard breast imaging
- Where
- 2 sites in Denmark
- Volunteers
- 227 people
- Sponsor
- Aarhus University Hospital
Child Health, Child Behavior
Children's Cooperation Denmark: a 3-year System Dynamics Trial
Lack of physical activity (PA) and sedentary lifestyle in Danish children is a major challenge. New strategies are needed to combat this development.
- Conditions
- Child Health, Child Behavior, Physical Inactivity, Child Obesity
- Trial name
- Child-COOP (NCT06185413)
- Testing
- Participatory system dynamics approach
- Where
- 5 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Hyperparathyroidism, Primary
Autofluorescence in Surgery for Primary Hyperparathyroidism
The study aims to test if autofluorescence imaging (AF) is a useful surgical aid during parathyroidectomy (PTX) for primary hyperthyroidism (PHPT).
- Trial name
- NCT06230380
- Testing
- Surgery with autofluorescence
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Rectal Prolapse, Surgery
The Nordic Rectal Prolapse Study
The goal of this observational study is to gather data about surgical procedures for rectal prolapse in adult human subjects. The main question it aims to answer is: Which procedure is best for treating external rectal prolapse?…
- Conditions
- Rectal Prolapse, Surgery, Recurrence, Quality of Life
- Trial name
- NORDIC (NCT05569980)
- Where
- Denmark
- Volunteers
- 430 people
- Sponsor
- Aarhus University Hospital
Insomnia Chronic
Determination of Optimal Sleep Treatment Elements (The DOSE Project) - DISA
Insomnia is a widespread public health challenge considering its impact on daily life, comorbidity with other disorders, and socio-economic costs.
- Trial name
- DISA (NCT06781203)
- Testing
- Digitally delivered CBTI (eCBTI)
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aarhus University Hospital
Insomnia, Cognitive Impairment
RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
The goal of the study is to investigate whether treating insomnia using app-based cognitive behavioral therapy for insomnia (CBT-I) can improve cognitive impairment in breast cancer survivors compared to an active control group…
- Conditions
- Insomnia, Cognitive Impairment, Breast Cancer
- Trial name
- RESET-BRAIN (NCT06553235)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep hygiene education
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Aarhus University Hospital
Tracheostomy
Consequence of Open Versus Closed Tracheostomy Immediately After Decannulation
Tracheostomy is performed for prolonged mechanical ventilation. Ineffective bandaging following decannulation leaves the tracheostomy wound unsealed, reducing pulmonary function, coughing ability, and voice quality, ultimately…
- Trial name
- NCT06138093
- Testing
- Sealing device, No device
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital
Melanoma, Cognitive Impairment
Cognitive Function in Melanoma Patients Treated With Adjuvant Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) are a group of novel immunotherapies that boost the body's own defense against the cancer by improving the immune system's ability to recognize and destroy cancer cells.
- Conditions
- Melanoma, Cognitive Impairment, Fatigue, Sleep
- Trial name
- NCT04565769
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital