Clinical trials: sponsored by Aarhus University Hospital
Heart Failure, Sarcopenia
Mechanism of Sarcopenia in Heart Failure
The aim of the study is to provide information on the interaction between socioeconomic factors, daily physical activity, nutrition and lifestyle on loss of muscle mass and muscle function in patients with heart failure.
- Conditions
- Heart Failure, Sarcopenia, Cachexia
- Trial name
- MUSCLE-CHF (NCT05063955)
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Functional Gastrointestinal Disorders
Internet-delivered CBT for Functional Gastrointestinal Disorders (FGID) in Youth: a Single Case Experimental Design
Functional gastrointestinal disorders (FGID) are common among children and adolescents. They affect quality of life, cause functional disability, school absence and high health care use.
- Trial name
- NCT05237882
- Testing
- Internet delivered cognitive behavioural therapy for functional gastrointestinal disorders
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Aarhus University Hospital
Chronic Obstructive Pulmonary Disease, Emphysema or COPD
The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility
In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the…
- Trial name
- NCT06163131
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Aarhus University Hospital
Prostate Cancer
Danish Prostate Cancer Consortium Study-1
The purpose of the study is to investigate if a new promising microRNA-based urine biomarker test for prostate cancer, called uCaP, is better than the current standard test (PSA) to identify men who would benefit from an MRI scan…
- Trial name
- DPCC-1 (NCT05767307)
- Where
- 3 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Aarhus University Hospital
Coronary Heart Disease, Angina Pectoris
SORT OUT X - Combo Stent Versus ORSIRO Stent
The aim of the Danish Organisation for randomised trials with clinical outcome (SORT OUT) is to compare the safety and efficacy of the ComboTM stent and Orsiro™ stent in the treatment of unselected patients with ischemic heart…
- Conditions
- Coronary Heart Disease, Angina Pectoris, Myocardial Infarction
- Trial name
- SORT OUT X (NCT03216733)
- Testing
- COMBO, ORSIRO
- Where
- 4 sites in Denmark
- Volunteers
- 3,148 people
- Sponsor
- Aarhus University Hospital Skejby
Compliance, Patient
Treatment of Latent Tuberculosis in Socially Marginalised Citizens
An open-label, randomised controlled trial comparing compliance to treatment for latent tuberculosis infection in socially marginalised citizens.
- Trial name
- DOT-LTBI (NCT03266991)
- Testing
- Rifapentine, Isoniazid
- Where
- 2 sites in Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Irritable Bowel, Fibromyalgia
Psychiatric Disorders and Functional Somatic Disorders
The objectives of this study are: Firstly, to investigate the association between psychiatric disorders and functional somatic disorder (FSD).
- Conditions
- Irritable Bowel, Fibromyalgia, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT06006715
- Volunteers
- 7,493 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Acute Lymphoblastic Leukemia
The Association Between Asparaginase Enzyme Activity Levels and Toxicities in Childhood Acute Lymphoblastic Leukaemia in NOPHOALL 2008
Evaluation of the association between risk and severity of asparaginase associated toxicities and asparaginase enzyme activity levels in children with Acute Lymphoblastic Leukemia treated in the NOPHO-ALL 2008 protocol.
- Trial name
- NCT04187248
- Testing
- Asparaginase
- Where
- Denmark
- Volunteers
- 1,248 people
- Sponsor
- Aarhus University Hospital
Coronary Artery Disease
Miniaturized Extracorporeal Circulation Study
Rationale: Contemporary coronary artery bypass grafting (CABG) continues to be associated with a significant risk of postoperative bleeding.
- Trial name
- NCT03216720
- Testing
- CABG, Miniaturized extracorporeal circulation, Conventional extracorporeal circulation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital Skejby
Heart Surgery, Chest Tube
Timing for Removal of Chest Tubes in Adult Cardiac Surgery
Rationale: Evidence regarding the timing of chest tube removal after cardiac surgery is sparse. The timing of chest tubes removal constitutes a balancing act between risk of retained blood syndrome, infection, patient discomfort…
- Conditions
- Heart Surgery, Chest Tube, Effusion Pleural, Pain, Postoperative
- Trial name
- NCT04487262
- Testing
- Cardiac surgery
- Where
- Denmark
- Volunteers
- 515 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Bypass Surgery, Right-Sided Heart Failure
The SWEDEGRAFT Right-Heart-Substudy
BACKGROUND Right ventricular dysfunction is a common echocardiographic finding after cardiac surgery. Pericardial disruption has been suggested as the most probable cause as the phenomenon occurs within minutes after pericardial…
- Trial name
- NCT05049421
- Testing
- Echocardiography
- Where
- Denmark
- Volunteers
- 207 people
- Sponsor
- Aarhus University Hospital Skejby
Necrotizing Soft Tissue Infection
Characteristics of Patients With Necrotizing Soft Tissue Infections
To study the demographic characteristic of patients with necrotizing soft tissue infections.
- Trial name
- NCT04801615
- Testing
- Surgery
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Coronary Artery Disease, Exercise
Effect of Long-term Exercise on Haemostasis and Inflammation in Patients With Coronary Artery Disease
Introduction: Regular exercise training improves prognosis in patients with coronary artery disease (CAD). This study investigates whether the beneficial effects of exercise can be partly explained by favourable changes in…
- Conditions
- Coronary Artery Disease, Exercise, Inflammation, Hemostasis
- Trial name
- NCT04268992
- Testing
- Long-term exercise
- Where
- Faroe Islands
- Volunteers
- 142 people
- Sponsor
- Aarhus University Hospital
Coronary Artery Stenosis
iNav-based, Automated Coronary Magnetic Resonance Angiography for the Detection of Coronary Artery Stenosis
Ischaemic Heart Disease (IHD) is the worlds leading cause of death. IHD is often caused by a narrowing of the coronary arteries, which prevents blood from flowing to the heart muscle, causing pain and damage to the heart.
- Trial name
- iNav-AUTO CMRA (NCT05473117)
- Testing
- Coronary Magnetic Resonance Angiography (CMRA)
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Aarhus University Hospital
Transthyretin Amyloid Cardiomyopathy, Heart Failure
Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction
Clinical comparison of patients with transthyretin cardiac amyloidosis and patients with heart failure with reduced ejection fraction
- Trial name
- NCT05896904
- Testing
- Echocardiography
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital Skejby
Bladder Cancer, Renal Cancer
Gag-layer in the Urothelium of the Human Upper Urinary Tract
Urothelial carcinomas of the lower and upper urinary tract can be considered "twin diseases". Much of the current clinical decision-making surrounding Upper Tract Urothelial Carcinoma (UTUC) is extrapolated from evidence that is…
- Trial name
- NCT05400291
- Testing
- Chondroitin Sulfate Staining
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Aarhus University Hospital
Narrow Band Imaging in Flexible Cystoscopy
Narrow Band Imaging in Flexible Cystocopy
Patients with first time hematuria or patients previously diagnosed with papillomas/CIS of the bladder are included in the study. All surgeons are highly experienced in WL cystoscopy and familiar with NBI findings.
- Trial name
- DaBlaCa-7 (NCT02313636)
- Where
- 3 sites in Denmark
- Volunteers
- 955 people
- Sponsor
- Aarhus University Hospital
Non-muscle Invasive Bladder Cancer
Clinical and Functional Consequences of Photodynamic Diagnosis (PDD) and Intravesical Instillation Therapy
The aim is to evaluate and compare treatment strategies for non-muscle invasive bladder cancer. Furthermore, the impact of intravesical instillations on bladder function will be examined by urodynamic examination both prior to…
- Trial name
- URODYN (NCT04943094)
- Testing
- Urodynamic examination
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital
Acute Ischemic Stroke
Acute Subcutaneous SemaglutidE in Acute Ischemic sTroke
Can Semaglutide help reduce the damage caused by a stroke? ASSET trial is a national, multicenter, clinical trial, investigating the safety and efficacy of Semaglutide in non-diabetic patients with acute ischemic stroke.
- Trial name
- ASSET (NCT05630586)
- Testing
- Semaglutide, Standard care
- Where
- Denmark
- Volunteers
- 380 people
- Sponsor
- Aarhus University Hospital
Rectal Cancer, Recurrence
Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients
This study investigates the potential benefit of re-irradiation of patients with locally advanced rectal recurrences, by a prospective phase II clinical, imaging and translational research study.
- Conditions
- Rectal Cancer, Recurrence, Radiation Toxicity
- Trial name
- Re-RAD-I (NCT05816980)
- Testing
- Hyperfractionated external beam radiation
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 16 people
- Sponsor
- Aarhus University Hospital