Clinical trials: sponsored by Akdeniz University
Periodontitis, Type 2 Diabetes Mellitus (DM)
Evaluation of MTHFR and DNMT3B Gene Polymorphisms Along With Periodontal Clinical Parameters in Healthy Individuals and Individuals With Type 2 Diabetes and Periodontitis
Periodontitis is a chronic inflammatory disease that affects the tissues supporting the teeth and can lead to progressive tissue destruction.
- Trial name
- NCT07905209
- Testing
- MTHFR and DNMT3B Genetic Polymorphism Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Self Harm
The Impact of a Nursing Care Program Based on Human Caring Theory on Adolescents With Self-harm
The aim of this study is to examine the effect of a Nursing Care Program based on Human Caring Theory on self-esteem, coping, and self-compassion in adolescents exhibiting self-harming behavior.
- Trial name
- NCT07368556
- Testing
- Group receiving Nursing Care Program based on Human Caring Theory, Group receiving routine treatment and follow-up at the polyclinic.
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Akdeniz University
Delayed Onset Muscle Soreness (DOMS)
Effects of Sports Massage and Thai Massage on Delayed-Onset Muscle Soreness and Recovery
This study investigated the effects of sports massage and modified traditional Thai massage on delayed-onset muscle soreness (DOMS) and recovery following strenuous exercise in healthy, physically inactive young men.
- Trial name
- NCT07892118
- Testing
- Sports Massage, Traditional Thai Massage, Passive Recovery
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
68 Children Aged 7-10
The Effect of Storytelling With Metaphor Toys on Fear and Anxiety Levels in Children
The hospital environment is an unfamiliar environment for children, and unfamiliar people, unknown medical tools and equipment, sounds, and medical procedures in this environment can cause negative emotional states such as fear…
- Trial name
- NCT06611605
- Testing
- Storytelling with metaphor toys
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hypertension, Periodontitis
Evaluation of MTHFR Gene Polymorphism and Periodontal Clinical Parameters in Healthy, Hypertensive, and Periodontitis Individuals
This observational study aims to evaluate the relationship between MTHFR gene polymorphisms and periodontal clinical findings in healthy individuals, individuals with hypertension, individuals with periodontitis, and individuals…
- Trial name
- NCT07873385
- Testing
- MTHFR Gene Polymorphism Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Black Stains
Assessment of Black Stains on Teeth in Relation to Salivary Parameters, Periodontal Health, and Body Mass Index in Children
Objective The aim of this study is to compare salivary flow rate, salivary pH, salivary buffering capacity, plaque index, gingival index, DMFT/dft indices, and body mass index (BMI) in systemically healthy children aged 5-10…
- Trial name
- NCT06985446
- Testing
- Study Group:Black stain-positive, Control Group: Black stain-negative
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infant, Premature, Diseases, Premature Birth of Newborn
Elevated Midline Positioning During Diaper Change in Preterm Infants
Diaper changing is one of the most frequent routine care procedures in the neonatal intensive care unit (NICU) and is known to cause physiological instability and behavioral stress responses in preterm infants.
- Conditions
- Infant, Premature, Diseases, Premature Birth of Newborn, Pain
- Trial name
- NCT07865897
- Testing
- 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
Juvenile Idiopathic Arthritis (JIA)
YOGA FOR CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS
Juvenile Idiopathic Arthritis (JIA) is a chronic autoimmune condition starting before age 16, often leading to fatigue, joint stiffness, and decreased physical activity.
- Trial name
- JIA (NCT07661069)
- Testing
- Telerehabilitation-Based Yoga Group, Standard Home-Based Physical Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Akdeniz University
Pain, Fear
The Effect of Buzzy® and a Stress Ball on Reducing Pain and Fear During Peripheral Intravenous Cannulation in Children
This study aims to compare the effects of Buzzy®, a device that applies cold and vibration, and a stress ball on pain and fear during intravenous catheter insertion in children aged 7-12 years.
- Conditions
- Pain, Fear, Pain Management
- Trial name
- NCT07851909
- Testing
- Buzzy, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Anxiety, Pain
Effect of Recreational Play Activities on Anxiety in Children Receiving Chemotherapy and Their Parents
This single-group pretest-posttest study evaluated changes in anxiety levels among children undergoing inpatient chemotherapy and their parents following nurse-led recreational play activities.
- Trial name
- NCT07348900
- Testing
- Nurse-Led Recreational Play Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Exergaming, Virtual Reality Physical Activity
Virtual Reality Exergaming During Work Breaks in Office Employees
The goal of this trial is to learn how different exercise formats used during workplace breaks affect the immediate physical and emotional responses of office employees.
- Conditions
- Exergaming, Virtual Reality Physical Activity, Workplace Exercise
- Trial name
- NCT07749196
- Testing
- Gamified Virtual Reality Exergaming (GVRE), Serious Virtual Reality Exergaming (SVRE), Traditional Video Exercise (TVE)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cerebral Perfusion, Cerebral Oxygenation
Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia
The goal of this observational study is to determine the correlation between cerebral oxygenation values measured by near-infrared spectroscopy (NIRS) and other routine monitoring parameters in patients placed in the semi-sitting…
- Conditions
- Cerebral Perfusion, Cerebral Oxygenation, Hemodynamic Monitoring, Semi-sitting Position
- Trial name
- NCT07270341
- Testing
- Near-Infrared Spectroscopy (NIRS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Akdeniz University
Support of the Family as a Caregiving System
The Effect of an Electronic Decision Support System on Preventing Pressure Ulcers and Urinary Infections in Home Care
This study evaluated Care-Up, a mobile-compatible web-based decision support system for informal caregivers of patients receiving home healthcare.
- Trial name
- CARE-UP (NCT06927479)
- Testing
- Care-Up Electronic Decision Support System
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Akdeniz University
Peri-Implant Diseases
Salivary Biomarkers in Different Implant-Supported Prostheses
This observational cross-sectional study compared salivary biomarkers among adults with different types of implant-supported prosthetic rehabilitation and periodontally healthy adults with natural teeth.
- Trial name
- NCT07813845
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Parent, Anxiety
Effect of Progressive Muscle Relaxation on Parental Anxiety
This randomized controlled trial aims to evaluate the effect of progressive muscle relaxation exercises on anxiety levels among parents who are the primary caregivers of children diagnosed with cancer and receiving inpatient…
- Conditions
- Parent, Anxiety, Cancer, Progressive Muscle Relaxation
- Trial name
- PMR-PA (NCT07797608)
- Testing
- Progressive Muscle Relaxation
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Adolescent Idiopathic Scoliosis
Investigation of Muscle Activity With sEMG, Surface Topography and Radiographic Changes of Paraspinal Muscles in Individuals With Adolescent Idiopathic Scoliosis.
The aim of this study is to examine paraspinal muscle activity, body surface topography, posture, and radiographic characteristics in adolescents with idiopathic scoliosis.
- Trial name
- NCT07804836
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Genu Varum
Genu Varum, Change of Direction, and Reactive Agility in Youth Football Players
The goal of this observational study is to compare change-of-direction (COD) and reactive agility (RA) performance between football players with and without genu varum and to examine whether lower-limb alignment is associated…
- Trial name
- NCT07798869
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Attention-Deficit/Hyperactivity Disorder (ADHD)
Investigation of the Association of Multimodal Neuroimaging and Peripheral Biomarkers With Executive Functions and Emotional Regulation in Adolescents With Attention-Deficit/Hyperactivity Disorder
The purpose of this observational study is to investigate the relationships among resting-state brain connectivity, peripheral blood biomarkers, executive functions, and emotional regulation in adolescents with…
- Trial name
- NCT07800117
- Testing
- No Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Anxiety
Human Caring Theory-Based Yoga and Anxiety
This controlled interventional study aims to evaluate the effect of a Human Caring Theory-based yoga program on state anxiety levels in adolescents diagnosed with cancer.
- Trial name
- HCT-YA (NCT07797595)
- Testing
- Human Caring Theory-Based Individualized Online Yoga Program
- Volunteers
- 112 people
- Sponsor
- Akdeniz University
Nursing Education
Humanistic Approach-Based Caring Relationship Teaching in Nursing Students
This randomized controlled study aims to evaluate the effect of individualized caring relationship teaching based on Paterson and Zderad's Humanistic Nursing Approach on caring-oriented nurse-patient interaction among first-year…
- Trial name
- NCT07786948
- Testing
- Standardized-Patient Simulation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Akdeniz University