Clinical trials: sponsored by Al-Azhar University
Obturation
The Effect of Clinical Experience on the Quality of Obturation and Periapical Changes of Teeth Treated With Matched Cones in Combination With Bioceramic Sealer
Evaluation of the impact of clinical experience on the quality of obturation and periapical changes of clinical cases using lateral compaction with bioceramic sealers and matched cone obturation with bioceramic sealers both…
- Trial name
- NCT06260423
- Testing
- Experienced dentist using lateral compaction with bioceramic sealer., Unexperienced dentist using lateral compaction with bioceramic sealer., Experienced dentist using Single cone with bioceramic sealer.
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Non-muscle-invasive Bladder Cancer
Safety and Efficacy of Scheduled Intravesical Gemcitabine Versus Intravesical BCG for Intermediate and High Risk Non Muscle Invasive Bladder Cancer: A Prospective, Randomized Study
About 40%-80% of NMIBC recur within 6-12 months when managed with TURBT alone, and 10%-25% of the patient's progress to muscle invasive disease.
- Trial name
- NCT05626101
- Testing
- BCG, Gemcitabine
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Al-Azhar University
Hypospadias
Efficacy of Fibrin Sealant in Hypospadias Surgery
The aim of the study was to evaluate if application of a fibrin sealant over the urethroplasty suture line for waterproofing instead of a dartos vascularized pedicled flap to reduce complications and improve the outcome in…
- Trial name
- NCT05666206
- Testing
- fibrin sealant in hypospadias
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Periodontal Diseases
Effect of Probiotics on Periodontitis Stage III Grade C Molar-incisor Pattern
the research highlight the effectiveness of probiotics as adjuncts to SRP in the treatment of periodontitis stage III grade C molar-incisor pattern
- Trial name
- RCT (NCT06253988)
- Testing
- Probiotic Formula
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Carious Teeth, Adaptation
Marginal Evaluation of Zirconia Reinforced Lithium Disilicate Partial Coverage Restoration of Egyptian Posterior Teeth.
Objective: To evaluate the marginal adaptation of the zirconia reinforced lithium disilicate (VITA AMBRIA) glass ceramic Inlay/Onlay compared with lithium disilicate(IPS emax Press) glass ceramic Inlay/Onlay in decayed posterior…
- Trial name
- NCT05281861
- Testing
- Zirconia reinforced Lithium disilicate (Vita Ambria) ceramic onlay restoration, Lithium disilicate (IPS e-max press) ceramic onlay restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Emergencies
Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation
Mivacurium can be considered as an optimal choice for muscle relaxation in short duration surgeries, as butyrylcholinesterase can rapidly and reliably degrade this benzylisoquinoline muscle relaxant in vivo.
- Trial name
- RSI (NCT06072534)
- Testing
- "Mivacurium Chloride"
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Opioid Use
Opioid Free Anaesthesia Versus Opioid Based Anesthesia for Laparscopic Cholecystectomy
The aim of this study is to compare the efficacy of Opioid-free anesthesia (OFA) with opioid anaesthesia (OA) in patients undergoing laparoscopic cholecystectomy (LC).
- Trial name
- NCT06231992
- Testing
- opioid anaesthesia, Opioid free anaesthesia
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Periodontitis, Gingivitis
Regulatory T Cell With Related Interleukins in Periodontal Disease Progression
T Regulatory cells which suppressor subset of T cells and related cytokines remain in blood and infiltrates into the tissue under need.
- Trial name
- NCT06135116
- Testing
- Flow Cytometric Detection of Regulatory T Cells and Cytokines analysis by ELISA
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Atrophic Acne Scar
Combined Procedures in the Treatment of Severe Acne Scars
Many methods utilize for acne scar treatment including laser, cosmetic filler, microneedling, local tumescent, Subcision and chemical peels. These procedures can be used individually or as a combination therapy.
- Trial name
- NCT06227481
- Testing
- Scar subcision, Platelet rich plasma injection, Polydioxanone mono threads insertion
- Volunteers
- 48 people
- Sponsor
- Al-Azhar University
Sepsis, Obstructive Shock
Use of Renin Versus Lactic Acid as Tissue Perfusion Biomarkers for Mortality Prediction in Hypotensive Critically Ill Patients
Measurement of Whole Blood Lactate Concentrations Whole blood lactate concentrations will be measured at the time of study enrollment and at 24, 48, and 72 hours.
- Conditions
- Sepsis, Obstructive Shock, Critical Illness, Hypotensive
- Trial name
- NCT05810415
- Testing
- Renin levels and lactic acid levels
- Where
- 2 sites in Egypt
- Volunteers
- 84 people
- Sponsor
- Al-Azhar University
Orthopedic Disorder
Arthroscopic Partial Trapezictomy With Hematoma Distraction in Basal Thumb Arthritis
The basal joint, also referred to as the carpometacarpal (CMC) joint, of the thumb is one of the joints most commonly affected by arthritis.
- Trial name
- NCT05746091
- Testing
- wrist arthroscopy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Abnormal Uterine Bleeding
Evaluation of Abnormal Uterine Bleeding in Adolescents: A Cross Sectional Observational Study
Evaluation of Abnormal Uterine Bleeding in Adolescents: A Cross Sectional Observational Study
- Trial name
- NCT06201767
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Retinal Detachment
Evaluation of Vitrectomy With ILM Peeling in Myopic Macular Hole With Only Posterior Retinal Detachment
Retinal detachment (RD) resulting from the macular hole (MH), also known as MH-induced RD (MHRD), most commonly occurs in eyes with high myopia and results in irreversible visual disorders.
- Trial name
- NCT06194760
- Testing
- Vitrectomy with ILM peeling
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Al-Azhar University
Shoulder Injuries
Results of Distal Clavicle Graft in Shoulder Dislocation Clavicle Auto Graft in Patient With Recurrent Anterior Shoulder Dislocation
to evaluate the clinical and radiological Outcome of Distal Clavicle Auto graft in patient with recurrent Shoulder dislocation
- Trial name
- NCT06186362
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Accerleration of Tooth Movement
Assessment of Maxillary Canine Retraction Using Self-ligating Brackets System Assisted With Micro-osteoperforations
Assessment of maxillary canine retraction using self-ligating brackets system assisted with micro-osteoperforations: A prospective controlled clinical study
- Trial name
- NCT05595174
- Testing
- self ligating bracket with micro osteoperforation, conventional bracket with micro osteoperforation, conventional bracket without micro osteoperforation
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Anesthesia, Radical Mastectomy
Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II
Modified Radical Mastectomy accounts for 31% of all breast surgeries and considered the fundamental surgical management for breast cancer. Nearly 40-60% of patients experience severe acute postoperative pain.
- Trial name
- NCT06188156
- Testing
- Anethesia
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Al-Azhar University
Congenital Glaucoma
Non-penetrating Deep Sclerectomy Versus Trabeculotomy- Trabeculectomy Operation in Treatment of Primary Congenital Glaucoma
The high success rate of the non-penetrating deep sclerectomy (NPDS) procedure in adult glaucomatous patients motivated some glaucoma specialists to try it as an alternative procedure in childhood PCG.
- Trial name
- NCT06189326
- Testing
- non-penetrating deep sclerectomy, primary combined trabeculotomy-trabeculectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Intraoperative Hemodynamics, Liposuction
Effect of Adrenaline Concentration on Intraoperative Hemodynamics of Liposuction Patients
Liposuction is a procedure that has emerged over the last 30 years as a method to remove subcutaneous fat for cosmetic purposes.
- Trial name
- NCT05822765
- Testing
- Epinephrine concentration of 1:1000000, Epinephrine concentration of 1:500000
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Irreversible Pulpitis, Endodontic Inflammation
A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth
In this study, patients with symptoms of irreversible pulpitis in mature permanent molars were treated with two pulpotomies techniques after random allocation in either 2 groups: Diode laser pulpotomy and traditional pulpotomy…
- Trial name
- NCT06176378
- Testing
- traditional pulpotomy, diode laser pulpotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acne Vulgaris
Efficacy of Manuka Honey Nano-Formulation in the Treatment of Acne Vulgaris
The present study aims to manufacture manuka honey-loaded nano-formulation using natural materials as a potent tissue-healing remedy and compare it to commercially available antimicrobial therapy in order to reduce the severity…
- Trial name
- NCT06175819
- Testing
- Manuka honey( MgO 850, UMF+20) loaded nano-formulation
- Volunteers
- 102 people
- Sponsor
- Al-Azhar University