Clinical trials: sponsored by Al-Azhar University
Complete Edentulism
Comparison Between OT-Equator Versus Ball and Socket Attachment Systems in Implant-Retained Mandibular Complete Overdentures
This study compares two different attachment systems, OT Equator and Ball and Socket, used to retain mandibular complete overdentures supported by a single dental implant.
- Trial name
- NCT07804823
- Testing
- OT Equator Attachment System, Ball and Socket Attachment System
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Stage II Grade B Periodontitis
Clinical & Biochemical Evaluation of Antioxidant Vs. Chlorhexidine as an Adjunctive to Non-Surgical Treatment of Stage II-grade B Periodontitis
This randomized clinical trial aims to evaluate and compare the clinical and biochemical effects of an antioxidant agent and chlorhexidine when used as adjuncts to non-surgical periodontal therapy in patients with Stage II Grade…
- Trial name
- NCT07801417
- Testing
- Perioscience Gel, High Cure Chlorhexidine Gel, High Cure Chlorhexidine Gel + Perioscience Gel
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Al-Azhar University
Bacterial Colonization, Double-J Ureteral Stents
Risk Factors and Clinical Implications of Double-J Ureteral Stent Bacterial Colonization
This prospective cohort study will evaluate the risk factors associated with bacterial colonization of Double-J ureteral stents and examine its clinical implications.
- Trial name
- NCT07760792
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction, Tadalafil
Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erectile Dysfunction
This randomized trial will compare daily tadalafil 5 mg as adjunct therapy versus monotherapy in men with on-demand PDE5 inhibitor-resistant erectile dysfunction.
- Trial name
- NCT07753720
- Testing
- Tadalafil; Current on-demand PDE5 inhibitor, Tadalafil 5 mg
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Al-Azhar University
Percutaneous Nephrolithotomy
Flexible Nephroscopy-Assisted Single-Tract Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones
This randomized, parallel-group, non-inferiority trial will compare flexible nephroscopy-assisted single-tract percutaneous nephrolithotomy with conventional multi-tract percutaneous nephrolithotomy in patients with complex…
- Trial name
- NCT07753733
- Testing
- Flexible Nephroscopy-Assisted Single-Tract PCNL, Conventional Multi-Tract PCNL
- Where
- Egypt
- Volunteers
- 470 people
- Sponsor
- Al-Azhar University
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class II Malocclusion
Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion
The present study was conducted to evaluate the outcomes of conventionl versus 3D printed twin block appliances in growth modification of class II malocclusion (comparative clinical study) in both groups.
- Trial name
- RCT (NCT07792525)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Mycosis Fungoides of Skin (Diagnosis), Artificial Intelligence (AI) in Diagnosis
AI in MF Diagnosis
The aim of this observational study is to evaluate the diagnostic performance of an AI algorithm in the histopathological diagnosis of MF compared to certified dermatopathologists.
- Trial name
- AI\MF (NCT07795242)
- Testing
- this study does not include any intervention
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Zygomaticomaxillary Complex (ZMC) Fractures
Evaluation of Custom-Made Plates in the Treatment of Zygomaticomaxillary Complex (ZMC) Fractures.
This prospective, single-arm clinical trial evaluated the clinical and radiographic outcomes of custom-made, 3D-printed titanium plates in the surgical treatment of unilateral zygomaticomaxillary complex (ZMC) fractures.
- Trial name
- NCT07788885
- Testing
- Custom-made 3D-printed titanium plate
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Al-Azhar University
Seborrheic Keratoses, Artifical Intelligence
AI in SK Histopathological Diagnosis
The aim of this study is to evaluate the diagnostic performance of an Artificial Intelligence (AI) algorithm in the histopathological diagnosis of Seborrheic keratosis compared to Certified Dermatopathologists.
- Trial name
- AI\SK (NCT07787481)
- Testing
- This study doesn't include an intervention.
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Basal Cell Cancer
AI in Histipathological Diagnosis of Bcc
The goal of this study is to evaluate the diagnostic performance of an Artificial Intelligence (AI) algorithm in the histopathological diagnosis of bcc compared to certified dermatopathologists
- Trial name
- AI\bcc (NCT07786376)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Immediate Implant Placement in Chronic Infected Socket
Efficacy of Mixture of Vancomycin With Xenograft for Immediate Implant Placement in Chronic Infected Socket
Adding local vancomycin to xenografts greatly benefits stability, bone density, and limits marginal bone loss in dental implants in infected socket.
- Trial name
- RCT (NCT07784075)
- Testing
- immediate dental implants Placement in Chronic Infected Socket
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Erectile Dysfunction, Sexual Dysfunction
Male Sexual Function and Sexual Quality of Life in Polygamous Versus Monogamous Marriages
This web-based comparative cross-sectional survey will assess sexual function, sexual quality of life, psychological status, and marital satisfaction among Egyptian men in monogamous and polygamous marriages.
- Trial name
- NCT07783958
- Testing
- Monogamous marital structure, Polygamous marital structure
- Where
- Egypt
- Volunteers
- 1,820 people
- Sponsor
- Al-Azhar University
To Evaluate the Effectiveness of Intra-canal Nano-ketrolac as a Medicament in Reducing Post-endodontic Pain in Patients Undergoing Root Canal Treatment
The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain
After obtaining informed consent, the procedure begins with the administration of local anesthesia to ensure patient comfort. A standard approach involves using 2% lidocaine with 1:100,000 epinephrine, delivered either via…
- Trial name
- Post-Endodonti (NCT07064083)
- Testing
- intracanal nano-ketrolac, ketrolac gel
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Primary Monosymptomatic Nocturnal Enuresis
Bedtime Device Restriction and Desmopressin in PMNE.
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07776977
- Testing
- Desmopressin, Bedtime digital-device restriction
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al-Azhar University
Kidney Stone, Retrograde Intrarenal Surgery
Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones
Several studies evaluated the benefit of a short-term external ureteral catheter (UC) compared to double-J (DJ) ureteral stent after flexible ureteroscopy (URS); the results were controversial.
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery, Ureteral Stent
- Trial name
- NCT05738304
- Testing
- Retrograde intrarenal surgery with external ureteral catheter, Retrograde intrarenal surgery with double J internal ureteral stent
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Al-Azhar University
Renal Calculi
Role of Pre-stenting Before Retrograde Intrarenal Surgery With Miniaturized Flexible Ureteroscopes
This prospective randomized controlled trial will compare retrograde intrarenal surgery performed after routine preoperative ureteral stenting with direct retrograde intrarenal surgery without planned preoperative stenting in…
- Trial name
- NCT07773090
- Testing
- Preoperative double-J ureteral stenting followed by retrograde intrarenal surgery, Direct retrograde intrarenal surgery without planned preoperative ureteral stenting
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Al-Azhar University
Vasculogenic Erectile Dysfunction
Endothelial Markers and Tadalafil Response
This prospective cohort study will recruit eligible men attending the Urology/Andrology outpatient clinic. Baseline assessment will include demographic and clinical data, cardiovascular risk assessment, erectile-function…
- Trial name
- NCT07773103
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Periodontal Intrabony Defects, Stage III Grade B Periodontitis
Sub-junctional Pinhole Technique
Pinhole Regenerative Therapy (PRT) following minimally invasive non-surgical periodontal therapy (MINST) in the treatment of intrabony defects associated with Stage III Grade B periodontitis.
- Trial name
- PRT (NCT07763223)
- Testing
- Sub-junctional Pinhole Technique (S-PHT)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acne
577-nm Diode Laser in the Treatment of Non -Inflammatory Acne
The aim of this study is to evaluate the clinical efficacy and safety of the 577 nm diode laser in the treatment of non -inflammatory acne.
- Trial name
- NCT06909344
- Testing
- 577 nm Diode laser
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University