Clinical trials: sponsored by Al-Azhar University
Rhinitis
Nasal Packing Duration and Development of Pharyngitis After Septorhinoplasty Surgery
Septoplasty or septal reconstruction is a corrective surgical procedure performed to straighten the nasal septum. It may be associated with numerous complications.
- Trial name
- NCT06291402
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Preoperative Anxiety
Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery
Preoperative anxiety is a common issue in pediatric anesthesia. Children often experience anxiety and uneasiness due to uncertain outcomes.
- Trial name
- NCT06489327
- Testing
- melatonin (Circadin ®) 0.2 mg/kg, melatonin (Circadin ®) 0.4 mg/kg
- Where
- 2 sites in Egypt, Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Percutaneous Nephrolithotripsy (PCNL)
Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder Discomfort
The insertion of a urinary catheter in a patient undergoing a surgical procedure, especially urinary interventions, may lead to catheter-related bladder discomfort (CRBD) with varying degrees of severity during the postoperative…
- Trial name
- NCT06274333
- Testing
- Dexmedetomidine 0.5 mic/kg, Tramadol 1mg/kg, Paracetamol 10mg/kg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Abdominal Compartment Syndrome
Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication
An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti…
- Trial name
- NCT06291389
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Forearm Surgery, US-Guided Supraclavicular Block
Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
The etiology of tourniquet pain is complex, and the study team hypothesizes that blocking with Interscalene brachial plexus block (ISBPB) is more efficient in decreasing the incidence of tourniquet pain in comparison with other…
- Conditions
- Forearm Surgery, US-Guided Supraclavicular Block, Interscalene Analgesia, Tourniquet Pain
- Trial name
- NCT05602636
- Testing
- bupivacaine, midazolam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Vitiligo, Topical Fluorouracil
Topical 5-Fluorouracil Effervescent Powder in the Treatment of Vitiligo
A novel approach for 5-Fluorouracil delivery based on a solid effervescent formulation is proposed . 5-Fluorouracil is water soluble (~50mg/ml) and therefore has been used for the development of novel topical formulations…
- Conditions
- Vitiligo, Topical Fluorouracil, Effervescent Mixture
- Trial name
- NCT05536856
- Testing
- a new effervescent mixture 5-florouracil formula, 5-Fluorouracil plain powder
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Cesarean Section, Ultrasound Guided Transversus Abdominis Plane Block
Ultrasound Guided TAPB vs Surgical TAPB With Bupivacaine in Cesarean Section
The aim of this study is to compare Surgical Transversus abdominis plane block and Ultrasound guided transversus abdominis plane block (TAPB) as a postoperative analgesic regimen in female patients undergoing elective cesarean…
- Conditions
- Cesarean Section, Ultrasound Guided Transversus Abdominis Plane Block, Surgical Transversus Abdominis Plane Block, Bupivacaine
- Trial name
- NCT05750992
- Testing
- surgical TAP block, US guided TAP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Periodontitis Stage II
Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis
melatonin loaded in injectible platelet rich fibrin in treatment of periodontitis
- Trial name
- NCT07316582
- Testing
- Melatonin-Loaded Injectable Platelet-Rich Fibrin, injectible platelet rich fibrin (i-PRF )
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Lichen Planus, Oral
The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus
evaluate clinically and biochemically the efficacy of topically applied selenium as complementary or alternative to triamcinolone acetonide 0.1% and tacrolimus 0.1% in patients with oral lichen planus.
- Trial name
- RCT (NCT06362005)
- Testing
- Triamcinolone Acetonide 0.1% Oint, Tacrollimus Topical, Selenium
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Chronic Low Back Pain
Pain Neuroscience Education Combined With Lumbar Stabilization Exercises on Disability and Kinesiophobia Among Patients With Chronic Low Back Pain
This study will investigate the effect of adding Pain Neuroscience Education (PNE) to a standard lumbar stabilization exercise program on disability and kinesiophobia among patients with chronic low back pain in the Gaza Strip.
- Trial name
- NCT07307859
- Testing
- Experimental Group - Lumbar Stabilization Exercises + PNE, Control Group - Lumbar Stabilization Exercises Only
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Esthetic Zone
Efficacy of i-PRF Usage in Vestibular Socket Therapy
This study aims for evaluation of A novel method for evaluating i-PRF usage in vestibular socket therapy for immediate implant in defective fresh extraction site.
- Trial name
- NCT07304986
- Testing
- Immediate implant with VST, Immediate implant with VST and i-prf
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulmonary Atelectasis, Postoperative
Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery
the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include…
- Trial name
- LUS/PEEP/RM (NCT06654778)
- Testing
- PEEP, PEEP/RM, PEEP/RM/RF
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Malocclusion, Class I/II, Crowding
A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography
Comparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
- Conditions
- Malocclusion, Class I/II, Crowding, Maxillary First Molar Distalization
- Trial name
- MIDPAC (NCT07038902)
- Testing
- Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Shoulder Dislocation
Arthroscopic Subscapularis Augmentation
The glenohumeral joint is the most commonly dislocated joint of the human body, The stability of GH joint relies on a complex network of static and dynamic structures. Static stabilizers ::
- Trial name
- NCT07292740
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Edentulous Alveolar Ridge In Mandible, Edentulous Jaw
A Study Comparing Two Different Denture Base Materials in Implant Retained Overdentures
The aim of removable prosthodontics is not only to restore lost oral structures but also to preserve the remaining tissues. Implant-retained overdentures have shown superior outcomes over conventional dentures by reducing…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Edentulous Jaw, Edentulous Mouth, Implant Supported Overdenture
- Trial name
- NCT07271641
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Intrabony Defect, Intrabony Defects in Chronic Periodontitis
Treatment of Intrabony Defect in Patient With Periodontitis Stage III by Using I-PRF and Xenograft
Evaluate of the injectable platelet rich fibrin (I-PRF) with xenograft in Intrabony defects of Periodontitis patient stage III versus Xenograft alone.
- Trial name
- NCT07261878
- Testing
- injectable platelet rich fibrin and xenograft, Xenograft alone
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained Overdenture
The global increase in the aging population has led to a rise in total edentulism, which remains a major public health concern. two-implant-retained mandibular overdentures have been regarded as the standard of care, offering…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07250503
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
the Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain
Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain in Maxillary Premolars With Acute Irreversible Pulpitis
Post-endodontic pain refers to the discomfort experienced following endodontic procedures. The incidence of post-operative pain is reported to be 25-40% regardless of the pulp and periradicular condition.
- Trial name
- Instrumentatio (NCT07250399)
- Testing
- EdgeOne Fire reciprocating system, JZ file system
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Al-Azhar University
Non-vital Immature Anterior Teeth
Comparison Between Emdogain and Amniotic Membrane as a Scaffold in Endodontic Regeneration of Immature Anterior Teeth
To evaluate the clinical outcomes and cone-beam computed tomography findings of enamel matrix derivative and amniotic membrane in regenerative endodontic treatment of non-vital immature permanent anterior teeth
- Trial name
- NCT07252167
- Testing
- Regenerative endodontic treatment with conventional blood clot technique., regenerative endodontic treatment with emdogain., regenerative endodontic treatment with amniotic membrane
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Al-Azhar University
Effect of Piezocision and Injectable Platelets Rich Fibrin on Tooth Movement
Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction Orthodontic Canine Retraction: A Comparative Clinical Study
Comparison of piezocisin and injectable platelets rich fibrin during canine retraction
- Trial name
- NCT07239024
- Testing
- Iprf and piezocision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University