Clinical trials: completed, sponsored by Al-Azhar University
Dental Caries
Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics
There is limited data available on VITA AMBRIA glass ceramic , so this study is conducted to investigate the esthetic parameters of this new glass press system.
- Trial name
- NCT05437432
- Testing
- VITA AMBRIA, IPS e.max press
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Previous Endodontic Treatment Failure and Radiographically Confirmed Periapical Radiolucency
Efficacy of 810 nm Diode Laser Disinfection on Inflammatory Cytokines and Postoperative Pain After Endodontic Retreatment
The main cause of endodontic disorders is microbial infection. From the infected pulp tissue, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and…
- Trial name
- cytokines (NCT07141459)
- Testing
- 810 nm diode laser disinfection, Calcium Hydroxide Intracanal medication
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periapical Diseases
Effect of Combined Root Canal Therapies in Mandibular Molars With Coexistent Mature and Immature Apices on the Healing Outcome
Recent advancements in dentistry are driven by the development of dental materials and therapies that support tissue regeneration, including the application of bioactive, biocompatible calcium silicate-based materials like…
- Trial name
- NCT07891611
- Testing
- Bioceramic apical plug, Regenerative endodontic procedure
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Sepsis, Septic Shock
Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ
Study Title: Implementation of a Sepsis Management Protocol at Armed Forces Hospital Jazan (AFHJ). Purpose: The purpose of this quality improvement project is to determine if implementing a standardized, evidence-based "sepsis…
- Conditions
- Sepsis, Septic Shock, Systemic Inflammatory Response Syndrome (SIRS), Critical Illness
- Trial name
- NCT07460024
- Testing
- Adapted Surviving Sepsis Campaign (SSC) Protocol, Standard Clinical Care
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Polycystic Ovary Syndrome
Letrozole Versus Letrozole and Inositol
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders affecting women of reproductive age.
- Trial name
- NCT07873294
- Testing
- Letrozole tablets
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Plane Warts
Efficacy of Ivermectin in the Treatment of Plane Warts
This study aims to evaluate the efficacy of ivermectin in the treatment of plane warts( flat warts). patients diagnosed with plane warts will be included to assess the clearance ratre of the lesions.
- Trial name
- NCT07710638
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Labial Frenum Attachment, Gender Determination
Association Between Lip Print Patterns, Gingival Phenotype, Labial Frenum Attachment, And Gender Determination in A Group of Egyptians. A Cross Sectional Study.
This cross-sectional study aims to evaluate gingival phenotypes, cheiloscopic lip print patterns, and labial frenum attachment levels in healthy adult participants, and to investigate potential associations between these…
- Conditions
- Labial Frenum Attachment, Gender Determination, Lip Print
- Trial name
- NCT07854184
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Kidney Diseases
Cardio Protective Effect of SGL2I in Hemodialysis Patients and Its Impact on Patient Quality of Life
If this study has a cardio protective effect it will affect the mortality and morbidity of advanced CKD patients and improve their quality of life
- Trial name
- NCT06759077
- Testing
- Dapagliflozin (DAPA)
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Partially Edentulous Jaw
Evaluation of the Effect of PEEK Versus Co-Cr Digital Telescopic Mandibular Partial Denture on Patient Satisfaction and the Supporting Structure
This study evaluates and compares the clinical performance, retention, and patient satisfaction between Polyetheretherketone (PEEK) and Cobalt-Chromium (Co-Cr) digital telescopic mandibular removable partial dentures.
- Trial name
- NCT07849972
- Testing
- PEEK Telescopic Removable Partial Denture, Co-Cr Telescopic Partial Denture
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Diode Laser Therapy, Periodontal Disease
Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ.
Evaluation of the effect of liquorice nanogel versus diode laser on periodontitis stage Ⅲ clinically and microbiologically by molecular analysis of porphyromonas gingivalis using real time PCR.
- Conditions
- Diode Laser Therapy, Periodontal Disease, Liquorice Nanogel
- Trial name
- Periodontology (NCT07602738)
- Testing
- Liquorice Nanogel, diode laser
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Al-Azhar University
Treatment of Striae Alba
Compairing Micro Needling With Phenytoin Versus Microneedling Alone on Striae Alba
The aim of this study is to evaluate the efficacy and safety of Microneedling with Phenytoin versus Microneedling alone for the Treatment of Striae alba.The study is a comparative study which will be carried on 30 patients with…
- Trial name
- phenytoin (NCT07841366)
- Testing
- Phenytoin, Micro needling
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Neck Pain, Neck Pain Musculoskeletal
Sleep Hygiene Plus Physiotherapy for Sleep and Disability in Chronic Neck Pain
This study investigates the effectiveness of a combined intervention that integrates sleep hygiene education with physiotherapy exercises in patients suffering from chronic neck pain.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Sleep Disturbances, Fatigue, Mental
- Trial name
- NCT07178496
- Testing
- Sleep Hygiene Techniques, conventional physiotherapy program, Control arm
- Where
- Palestinian Territories
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Low Back Pain
Pilates and Resistance Training for Pain, Disability, and Sleep in Chronic Low Back Pain
This study will investigate the effect of Pilates and resistance training on pain, disability, and sleep quality in patients with chronic low back pain and sleep disturbances.
- Trial name
- NCT07291934
- Testing
- Combined Intervention (Pilates + Resistance Training), Pilates, Control (Usual Care)
- Where
- Palestinian Territories
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tongue Carcinoma, Tongue Neoplasms
Submental Island Flap vs Radial Forearm Free Flap in Tongue Reconstruction
This study evaluates and compares the postoperative surgical outcomes and quality of life (QoL) in patients undergoing tongue reconstruction after tongue cancer resection, comparing two reconstructive options: the Submental…
- Conditions
- Tongue Carcinoma, Tongue Neoplasms, Quality of Life
- Trial name
- SIPF-RFFF (NCT07819617)
- Testing
- Submental Island Pedicled Flap (SIPF), Radial Forearm Free Flap (RFFF)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Al-Azhar University
White Spot Lesion of Tooth
Effect of Diode Laser With Dye and Remineralizing Agent on Surface Area of White Spot Lesions by Using Digital Subtraction Radiograph Techniques.
The current study was conducted to compare effect of diode laser and perio green dye with reminerlizing agent on surface area white spot lesions by using digital subtraction radiographic techniques.
- Trial name
- NCT07818655
- Testing
- remin pro
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Psoriasis
Comparative Efficacy of Alpha Hydroxy Acids With and Without Nanocarriers Versus Calcipotriol Plus Betamethasone in Treatment of Plaque Psoriasis
The aim of this double blind comparative clinical study is to evaluate the efficacy of AHAs combined with nanocarriers and their use as a non steroidal alternative drug for long term management of plaque psoriasis
- Trial name
- NCT07816575
- Testing
- Alpha Hydroxy Acids with nanocarriers, Alpha Hydroxy Acids only., Calcipotriol plus betamethasone
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
TMJ Disc Displacement With Reduction
Evaluation of Intra-articular Injection of Hyaluronic Acid Versus Radiofrequency Current in Management of Reduced TMJ Disc Displacement
Aim of Study The aim of this study was to compare between three modalities in treatment of TMJ internal derangement aiming for optimizing treatment of this condition.
- Trial name
- NCT07802236
- Testing
- Hyalouronic acid, Radiofrequency
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Chronic Suppurative Otitis Media, Mastoid Cavity
Study the Impact of the Mastoid and Middle Ear Volume on the Success of Type 1 Tympanoplasty in Pediatric Age, With Comparing Using Cartilage and Fascial Grafts Through This, Strength the Hypothesis of That Total Tympanometry Volume Correlates With Ventilated Mastoid Air Cells Volume on CT Scans
The goal of this observational study is to know the impact of the mastoid and middle ear volume on the success of type 1 tympanoplasty in pediatric age, with a closer view on the comparison of using cartilage and fascial grafts…
- Conditions
- Chronic Suppurative Otitis Media, Mastoid Cavity, Pneumatization, Tympanoplasty
- Trial name
- NCT07806461
- Testing
- tympanoplasty type 1, Audiological Evaluation, HRCT scan temporal bone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Inferior Alveolar Nerve Block in Children
Clinical Success of 12 mm Needle IANB in Children
This prospective single-arm pilot study will evaluate the clinical success of an inferior alveolar nerve block performed using a 12 mm 30-gauge extra-short dental needle in children aged 4 to 12 years.
- Trial name
- NCT07791082
- Testing
- 12 mm 30-Gauge Extra-Short Dental Needle
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Complete Edentulism
Comparison Between OT-Equator Versus Ball and Socket Attachment Systems in Implant-Retained Mandibular Complete Overdentures
This study compares two different attachment systems, OT Equator and Ball and Socket, used to retain mandibular complete overdentures supported by a single dental implant.
- Trial name
- NCT07804823
- Testing
- OT Equator Attachment System, Ball and Socket Attachment System
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University