Clinical trials: sponsored by Alexandria University
Orbital Volume, Orbital Floor Reconstruction
Comparison Study Between Custom Made and Ready Made Titanium Mesh in Orbital Floor Reconstruction
compare between Custom made titanium mesh and ready-made titanium mesh in reconstruction of orbital floor.
- Trial name
- NCT07879729
- Testing
- reconstruction of orbital floor with custom made mesh, reconstruction of orbital floor with ready made mesh
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Severe Mental Illness, Bipolar Disorder
A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning…
- Conditions
- Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder
- Trial name
- MoodSync (NCT07879131)
- Testing
- MoodSync, Standard care
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Visceral Pain
Paragastric Neural Blockade and Laparoscopic Assisted Transversus Abdominis Plane Block on Visceral Pain After Surgery
after laparoscopic bariatric surgery, visceral pain (VP) remains a significant issue. VP causes autonomic symptoms, such as nausea and vomiting, and does not respond to conventional pain management methods that target incisional…
- Trial name
- NCT06973122
- Testing
- combined paragastric autonomic neural blockade and laparoscopic assisted transversus abdominis plane block, laparoscopic assisted transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 127 people
- Sponsor
- Alexandria University
Mental Health Stigma, Cognitive Flexibility
Integrated Mental Health Nursing Program: Effects on Stigma, Cognitive Flexibility, and Clinical Readiness
This quasi-experimental one-group pretest-posttest study aims to evaluate the effect of an Integrated Mental Health Nursing Educational Program on stigma, cognitive flexibility, and clinical readiness among undergraduate nursing…
- Conditions
- Mental Health Stigma, Cognitive Flexibility, Clinical Readiness, Mental Health Nursing Education
- Trial name
- IMHNEP (NCT07517861)
- Testing
- Integrated Mental Health Nursing Educational Program (IMHNEP)
- Where
- Egypt
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Stage III Periodontitis
Active Oxygen Releasing Gel With Photodynamic Therapy in Treating Stage III Periodontitis
Periodontitis is a serious gum disease that can damage the tissues supporting the teeth. The standard treatment is scaling and root planing of the teeth and roots.
- Trial name
- NCT07368699
- Testing
- Scaling and root planing, topical active oxygen-releasing gel, and photodynamic therapy using diode laser, Scaling and root planing and topical application of active oxygen-releasing gel, Scaling and root planing
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Alexandria University
Septic Shock, Sepsis
Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock Patients
The goal of this clinical trial is to assess the effect of targeting upper normal serum magnesium levels on norepinephrine requirements in adult patients with septic shock. The main questions it aims to answer are: 1.
- Trial name
- NCT07716956
- Testing
- magnesium sulfate, standard care treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Pleural Infection
Study of Medical Thoracoscopy in Early Pleural Infection
Pleural infection (which is the infection in the space around the lungs called the pleura) is a severe infection that is difficult to treat and can lead substantial disability or even death.
- Trial name
- STEP (NCT07858721)
- Testing
- Medical thoracoscopy plus standard of care, Standard of Care (Investigator Choice)
- Volunteers
- 128 people
- Sponsor
- Alexandria University
Pediatric Dental Anxiety, Pediatric Dental Pain
Brainwave Entrainment Technique in Managing Anxiety and Pain Perception in Pediatric Dental Patients.
Pediatric dental anxiety and pain management present significant clinical challenges during routine treatment. While conventional behavior management techniques exist, their inconsistent effectiveness necessitates the continuous…
- Trial name
- NCT07617662
- Testing
- Brainwave entrainment, Basic behavioral management technique
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Alexandria University
Hematologic Neoplasms, Gastrointestinal Symptoms
Effects of Synbiotic Supplementation on Gastrointestinal Symptoms, Appetite, and Nutritional Recovery in Patients After Autologous Bone Marrow Transplant
Patients undergoing autologous bone marrow transplantation (ABMT) receive high-dose chemotherapy and routine prophylactic antibiotics, which often disrupt the gut microbiome (dysbiosis).
- Conditions
- Hematologic Neoplasms, Gastrointestinal Symptoms, Malnutrition, Loss of Appetite
- Trial name
- NCT07845669
- Testing
- Tri-component Synbiotic Supplement
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Distal Hypospadias Repair
Topography Guided Repair Versus TIP for Distal Hypospadias
This study compares two surgical techniques used to repair distal hypospadias in children: topography-guided repair (TGR), a newer approach, and tubularized incised plate (TIP) repair, a commonly used standard technique.
- Trial name
- DPH repair (NCT07832760)
- Testing
- Topography Guided Repair, Tubularized Incised Plate Repair
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Alexandria University
Mandibular Fracture
Modified 3d Rectangular Grid Plate for Fixation of Anterior and Body Mandibular Fractures
Background: Fractures of anterior mandible (symphysis and parasymphysis) make up about 9% to 57%, of mandibular fractures, and body fractures make up about 21%; posing challenges for stabilization due to anatomical constraints.
- Trial name
- NCT07590401
- Testing
- Modified 3D Rectangular Grid plate, Two conventional miniplates
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Alexandria University
Mandibular Angle Fracture
Patient Specific 3d Titanium Plate Versus Standard Two Mini Plates in the Fixation of Mandibular Angle Fractures (a Randomized Controlled Clinical Trial)
To compare the effectiveness of custom-made (3D) titanium plates to standard two titanium mini plates in fixation of mandibular angle fracture.
- Trial name
- NCT07390734
- Testing
- custom-made 3D titanium plates, standared two mini plates
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
TMJ Disc Disorder
Arthrocentesis of Temporomandibular Joint Using Ozonated Water Alongside With Platelet Rich Plasma Injection in Management of Anterior Disc Displacement Without Reduction:
Background: The temporomandibular joint (TMJ) is a highly intricate and complex synovial joint found in the human body. When TMJ dysfunction occurs, it causes pain and difficulties in opening the mouth, significantly impacting…
- Trial name
- NCT07452289
- Testing
- Ozonated water and PRP injection, Ozonated water
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Procedural Pain
Stress-Ball Distraction for Pain and Anxiety During Painful Procedures in Critically Ill Patients
This study will examine whether using a small hand-held stress ball during painful procedures can help critically ill adult patients feel less pain and anxiety.
- Trial name
- NCT07836842
- Testing
- Stress-Ball Distraction, Standard care
- Volunteers
- 104 people
- Sponsor
- Alexandria University
Anticholinergic Delirium, Clozapine Poisoning
Rivastigmine as an Antidote for Clozapine-induced Central Nervous System Depression and Delirium
This study aims to evaluate the clinical efficacy and safety of rivastigmine in reversing the full spectrum of anticholinergic delirium including hypoactive delirium which is presented with CNS depression and hyperactive or…
- Conditions
- Anticholinergic Delirium, Clozapine Poisoning, Antipsychotic Toxicity, CNS Depression
- Trial name
- NCT07545382
- Testing
- Rivastigmine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Colorectal Disease Requiring Elective Laparoscopic Resection, Colorectal Anastomotic Leak
ICG Fluorescence Angiography to Reduce Anastomotic Leak After Laparoscopic Colorectal Resection
This prospective randomized controlled trial evaluates whether intraoperative indocyanine green (ICG) fluorescence angiography reduces clinically significant anastomotic leakage after elective laparoscopic colorectal resection…
- Trial name
- NCT07826156
- Testing
- Visual assessment, ICG visuals assessment
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Ridge Augmentation
Autogenous Sticky Bone Plus Platelet-rich Fibrin Membrane Versus Xenograft With Collagen Membrane for Posterior Atrophic Mandible
Background: Teeth loss in the posterior mandible initiates residual ridge resorption, this causes difficulty in implant placement so ridge augmentation must be done either simultaneous with implant placement or in a staged…
- Trial name
- NCT07825896
- Testing
- autogenous sticky bone + PRF membrane, Xenograft + collagen membrane
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Radiation-induced Oral Mucositis, Head and Neck Cancer
Citrus Sinensis Peel Gel for Radiation-Induced Oral Mucositis
This randomized controlled clinical trial aims to evaluate the efficacy of Citrus sinensis peel extract gel in the treatment of radiation-induced oral mucositis in head and neck cancer patients.
- Trial name
- NCT07813923
- Testing
- Citrus sinensis peel extract gel, Conventional supportive treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Blood Loss After a Total Hip Replacement
Evaluating the Effectiveness of Intramuscular Versus Intravenous Tranexamic Acid for Minimizing Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial
Intramuscular vs. Intravenous Tranexamic Acid for Total Hip Arthroplasty
- Trial name
- NCT07817537
- Testing
- Tranexamic Acid (TXA) intarmuscular, Tranexamic Acid (TXA) intravenous
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hemodialysis, Hemodialysis Patient
Calm in the Storm: Reducing Night Pain and Enhancing Sleep Through a Nurse- Led Benson's Relaxation Intervention in Hemodialysis Patients
Patients undergoing maintenance hemodialysis (HD) frequently experience persistent pain and sleep disturbances which negatively influence their quality of life and overall wellbeing.
- Trial name
- NCT07814469
- Testing
- Benson's Relaxation Intervention
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University