Clinical trials: sponsored by Alexandria University
Periodontitis, Diabetes Mellitus
Endocan Biomarker Level in Gingival Crevicular Fluid in Periodontitis Patients With Type 2 Diabetes Mellitus
Aim of the current study was to evaluate Endocan biomarker level in gingival crevicular fluid of patients with stage 1 or 2 (mild to moderate) periodontitis with controlled type 2 diabetes mellitus (DM) and compare it to that in…
- Trial name
- NCT05667051
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Alexandria University
Nausea and Vomiting, Postoperative
Supplemental Perioperative Intravenous Crystalloids for Postoperative Nausea and Vomiting in Children Undergoing Oncological Surgery
Postoperative nausea and vomiting (PONV) is a common complication in the paediatric population and is a source of significant morbidity.
- Trial name
- NCT05658406
- Testing
- Ringer's Lactate, normal Saline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Bone Loss
Immediate Implant vs.Socket Shield Technique in Esthetic Zone
immediate implant placement versus socket shield approach
- Trial name
- Implants (NCT05658419)
- Testing
- socket sheild
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Deep Overbite
Deep Bite Correction Using Auxiliary Intrusion Cantilevers With Initial Archwires in Adolescents
The purpose of this study was to determine the effect of auxiliary intrusion cantilevers used with resilient archwires during the leveling and alignment phase in intruding lower incisors.
- Trial name
- NCT05654558
- Testing
- Auxiliary cantilever intrusion arches on initial archwires, Routine leveling and alignment
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Alexandria University
Renal Transplantation; Complication
Hypomagnesemia and Its Association With Calcineurin Inhibitors Use in Renal Transplant Recipients
To assess the prevalence and risk factors of hypomagnesemia and its association with calcineurin inhibitor use among Egyptian renal transplant recipients.
- Trial name
- NCT05352880
- Testing
- serum magnesium level, FEMg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Uremic Pruritis
Sertraline Effect in Uremic Pruritis
This study aims to assess the effect of sertraline on uremic pruritis in patients undergoing regular haemodialysis.
- Trial name
- NCT05341843
- Testing
- sertraline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Carbon Monoxide Poisoning
The Efficacy of L-Carnitine in the Management of Acute Carbon Monoxide Poisoning
Carbon monoxide (CO) poisoning results in high morbidity and mortality worldwide. CO is described as a "silent killer" because CO is colorless, odorless, and tasteless but highly toxic.
- Trial name
- NCT05647707
- Testing
- L-Carnitine
- Volunteers
- 72 people
- Sponsor
- Alexandria University
Invasive Cancer, Pediatric Cancer
Comparing TIVA Using Propofol or Dexmedetomidine Versus Sevoflurane During Anaesthesia of Children Undergoing Bone-Marrow Aspiration
No doubt that children facing surgical procedures are subjected to perioperative distressing, anxious and worrying periods. Several factors included; parental deprivation, anxiety, previously mismanaged experience and…
- Trial name
- NCT05636566
- Testing
- Sevoflurane, Propofol infusion for maintance, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Clozapine Poisoning
The Efficacy of L-Carnitine in the Management of Acute Clozapine Intoxication
Clozapine is a dibenzodiazepine that is used atypical antipsychotic drug. Clozapine-induced cytotoxicity could be attributed to increases in reactive oxygen species (ROS) that oxidize mitochondrial proteins and disrupt cellular…
- Trial name
- NCT05632094
- Testing
- L-Carnitine
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Ascites Hepatic
Empagliflozin as a Novel Therapy in Refractory Ascites
The aim of the present study is to investigate the safety, efficacy and cost-effectiveness of empagliflozin, a sodium glucose transporter 2 inhibitor, as an add on therapy to the standard care for refractory ascites in patients…
- Trial name
- NCT05430243
- Testing
- Empagliflozin 10 MG, Diuretics
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Alexandria University
Clinical Efficacy, Treatment Efficacy
Lubiprostone for Functional Constipation in the Under 18 Years Patients
The investigators will enroll subjects 8 - < 18 years of age, fulfilling Rome IV criteria for functional constipation. Participants will be randomly assigned to either Lubiprostone treatment (study group), or the control group…
- Conditions
- Clinical Efficacy, Treatment Efficacy, Drug Side Effect
- Trial name
- NCT05144295
- Testing
- Lubiprostone Pill, Lactulose Oral Liquid Product, Bisacodyl 5 MG
- Where
- 2 sites in Egypt
- Volunteers
- 274 people
- Sponsor
- Alexandria University
Anterior Open Bite Malocclusion
Stability of Anterior Open Bite Treatment Using Extrusion Arches
This study investigated treatment effects and stability of anterior open bite cases using extrusion arches
- Trial name
- NCT05599074
- Testing
- extrusion arch
- Where
- Egypt
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Medication Reconcilitation Upon Hospital Admission
The Impact Of Clinical Pharmacists Medication Reconciliation Upon Patients Admission To Reduce Medication Discrepancies.
It is a quazai one arm study shows the impact of the role of the clinical pharmacists through medication reconciliation to patients admitted to the emergency department .The main aim is to show if the pharmacists intervention is…
- Trial name
- NCT04395443
- Testing
- medication reconciliation
- Where
- Egypt
- Volunteers
- 161 people
- Sponsor
- Alexandria University
Post Operative Pulmonary Complications
HFNC Versus Oxygen Face Mask on Postoperative Pulmonery Complications
Eighty adult patients were randomly categorized into two equal groups (forty patients each): HFNC was applied to group I, and a simple oxygen face mask was applied to group II.
- Trial name
- NCT05548309
- Testing
- HFNC, Oxygen face mask
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Alexandria University
ERAS, Surgery
Enhanced Recovery After Spinal Surgery Protocol Versus Conventional Care in Non Insulin Diabetic Patients ( ERAS )
enhanced recovery after spinal surgery protocol (ERAS) versus conventional care in non insulin diabetic patients. Our hypothesis is that non-insulin dependent diabetic patients who will undergo lumbar decompression surgery…
- Conditions
- ERAS, Surgery, Non Insulin Dependent Diabetes Mellitus, Lumbar Spine Disease
- Trial name
- NCT05033899
- Testing
- ERAS protocol
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Alexandria University
hCG, FET
Administration of Human Chorionic Gonadotrophin Before Secretory Transformation of Frozen-thawed Embryo Transfer Cycles
Successful embryo implantation is complicated process that requires synchrony between good-quality embryos and receptive endometrium.
- Conditions
- hCG, FET, Frozen-thawed Embryo Transfe, Human Chorionic Gonadotrophin
- Trial name
- NCT05340010
- Testing
- Human Chorionic Gonadotrophin Intramuscular injection 10.000 IU
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Alexandria University
Pleural Infection
Antiseptic Irrigation for Pleural Infection
The antiseptic povidone-iodine can safely be instilled into the pleural for the purpose of pleurodesis. Pleural irrigation with antiseptics is used in adults with open drainage for chronic empyema and has been described in the…
- Trial name
- NCT04761133
- Testing
- Povidone-Iodine pleural irrigation
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Space Maintenance
The Effectiveness of Combined Design Nance/Transpalatal Arch Appliance in Maintaining Arch Dimensions After Premature Extraction of Primary Molars
This study will evaluate the effectiveness of N-TPA appliance compared to Nance SM in maintaining the arch dimensions after bilateral premature extraction of primary molars in children.
- Trial name
- NCT05514145
- Testing
- Nance/Transpalatal arch space maintainer, Nance space maintainer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Shock
Role of Echocardiography in Guiding Fluid Therapy in Shocked Patients With Impaired Cardiac Contractility in Emergency Department
fluid therapy is one of the cornerstones in the management of shock but may result in iatrogenic fluid overload .The aim of this study was to assess the role of echocardiography in guiding fluid therapy in shocked patients with…
- Trial name
- NCT05488730
- Testing
- passive leg raising test and fluid challenge
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Female Infertility
Effect of GH Administration in Poor Responders Undergoing Intracytoplasmic Sperm Injection (ICSI)
Despite the use of various treatment strategies, poor response to ovarian stimulation remains a major clinical challenge with lower chance to obtain sufficient number of oocytes and thus less likely to conceive with high risk of…
- Trial name
- NCT05281341
- Testing
- Growth Hormone
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Alexandria University