Clinical trials: sponsored by Alexandria University
Polycystic Ovary Syndrome (PCOS)
Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome
The study aims to compare the efficacy of Empagliflozin or Linagliptin as an alternative to Metformin for treatment of non-diabetic patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05200793
- Testing
- Empagliflozin 25 mg, Linagliptin 10 mg, Metformin 1500 mg
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Alexandria University
Fatty Liver, Nonalcoholic, Diabetes Mellitus, Type 2
Anti-diabetic Drugs and Fatty Liver Management
Type 2 DM is one of the major risk factors for development of non-alcoholic fatty liver disease. The pooled prevalence of fatty liver among diabetics is 54% (95% CI 45%-64%).
- Trial name
- NCT05041673
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Wound Heal, Pain, Postoperative
Dry Heat Versus Sitz Bath On Episiotomy Wound Heating And Pelvic Pain
Objective: To compare the effect of dry heat versus moist heat application on episiotomy wound healing and pain among postnatal mothers.
- Trial name
- Dry_Heat (NCT05186532)
- Testing
- Dry Heat Application, Moist Heat Application
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Mucositis
Effectiveness of Photo-biomodulation in the Treatment of Chemotherapy Induced Mucositis
The aim of the current study was to study the effect of diode laser in the treatment of chemotherapy induced mucositis in young patients suffering from leukemia
- Trial name
- NCT05181943
- Testing
- Simpler diode laser, Conventional symptomatic treatment
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Alexandria University
Local Anaesthetic Drug Adverse Reaction
Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars
Background: Exodontia poses a psychological threat for children, increasing the need for profound local anesthesia to assure painless extraction and maintain child cooperation on the dental chair.
- Trial name
- NCT04739735
- Testing
- Dental Local Anaesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Thrombectomy, Ischemic Stroke
Direct Mechanical Thrombectomy Versus Bridging Therapy
This study compares the efficacy and safety of direct mechanical thrombectomy versus bridging therapy in patients with anterior circulation large vessel occlusion in a cohort of patients treated at the stroke unit of a single…
- Conditions
- Thrombectomy, Ischemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis)
- Trial name
- NCT05155540
- Testing
- Trevo and or Merci devices for stent retreival, Penumbra system for stent aspiration, recombinant tissue plasminogen activator
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Alexandria University
Pleural Infection
Short Versus Long Antibiotic Course for Pleural Infection Management (SLIM Trial)
Infection of the pleural space is serious condition that requires hospitalization, invasive interventions and long courses of antibiotics[1].
- Trial name
- SLIM (NCT04615286)
- Testing
- Short course (2-3 weeks) of antibiotics, Standard (long course) of antibiotics
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Behavior, Child
Effect of Kangaroo Mother Care Versus Hammock Positioning
Aim This study aimed to investigate the effect of kangaroo mother care (KMC)versus hammock positioning (HP) on physiological indices and behavioral organization among preterm neonates.
- Trial name
- Kangaroo (NCT05165004)
- Testing
- Kangaroo Mother Care, Hammock Positioning, Routine Care of NICU
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Orthodontic Appliance
Effect of Low Level Laser Therapy on Orthodontic Miniscrew Displacement
EFFECT OF LOW LEVEL LASER THERAPY ON ORTHODONTIC MINISCREW DISPLACEMENT
- Trial name
- Miniscrew (NCT05092633)
- Testing
- Miniscrew
- Where
- 2 sites in Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Periorbital Disorder
Carboxytherapy for Periorbital Dark Circles
the study evaluates carboxytherapy for the treatment of periorbital dark circles
- Trial name
- NCT04745078
- Testing
- Caboxy30, Caboxy60
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pyogenic Granuloma of Gingiva
Effectiveness of Diode Laser and Sclerotherapy in Treatment of Oral Pyogenic Granuloma
To clinically assess the effectiveness of diode laser versus sclerotherapy in the treatment of oral pyogenic granuloma. A randomized-controlled clinical trial conducted on 20 patients with oral pyogenic granuloma.
- Trial name
- NCT05099081
- Testing
- diode laser application, intra-lesional injection of ethanolamine oleate
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hepatocellular Carcinoma, Liver Cirrhosis
The Role of Long Non-coding RNAs WRAP53 and UCA-1 as Potential Biomarkers in Diagnosis of Hepatocellular Carcinoma
The aim of this work is to study the role of long non-coding RNAs WRAP53 and urothelial carcinoma-associated 1 (UCA1) as potential biomarkers in diagnosis of hepatocellular carcinoma.
- Conditions
- Hepatocellular Carcinoma, Liver Cirrhosis, Diagnoses Disease
- Trial name
- NCT05088811
- Testing
- WRAP53, UCA-1
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pain, Distress, Emotional
Mother Scented Simulated Hand for Mechanically Ventilated Preterm Neonates During Invasive Procedures?
This study aimed to determine the effect of Mother-Scented Simulated Hand (MSSH) on promoting comfort among mechanically ventilated preterm neonates during invasive procedures.
- Trial name
- Zaky-Hand (NCT05080582)
- Testing
- Mother-Scented Simulated Hand, NICU Standard Care
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Carpal Tunnel Syndrome
Radiofrequency, Perineural Injection, Idiopathic Carpal Tunnel Syndrome
Aim of the study The aim of the study is to evaluate the role of pulsed radiofrequency versus platelet rich plasma injection in treatment of idiopathic mild to moderate carpal tunnel syndrome Patients will be classified into…
- Trial name
- NCT05053477
- Testing
- mehylprednisolone injection, pulsed radiofrequency (PRF), platelet-rich plasma
- Where
- 2 sites in Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pelvic Floor Disorders
Evaluation of Levator Ani Muscle Injury in Primiparous
pelvic floor muscles play an important role in supporting the pelvic organs. Vaginal birth leads to defects in pelvic muscles and hence subsequent pelvic organ prolapse and urinary and fecal incontinence can occur .
- Trial name
- ULTRASOUND (NCT04980235)
- Testing
- transperineal 3D ultrasound
- Where
- Egypt
- Volunteers
- 355 people
- Sponsor
- Alexandria University
Osteopenia of Prematurity
Low and High Doses of Prophylactic Vitamin D in Prevention of Osteopenia of Prematurity
In this study the effects of low and high doses of prophylactic vitamin D on biochemical and radiological manifestations of osetopenia of prematurity will be tested.
- Trial name
- NCT04768439
- Testing
- Low Dose Vitamin D, High Dose Vitamin D
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Changes in Bacterial Count in Axilla After Laser Hair Removal
The Effect of Long-pulsed 1064 nm nd: Yag Laser-assisted Hair Removal on Some Skin Flora and Pathogens: an in Vivo Study
1. To evaluate the effect of ND-YAG laser hair removal on some skin flora and pathogens: an in vivo study. 2. To determine the immediate and long term effect of ND-YAG laser on total viable bacterial count, some skin flora and…
- Trial name
- NCT05034237
- Testing
- ND;YAG 1064NM LASER
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Changes in Facial Muscles Following Filler Injection
Dynamic Changes in Some Facial Muscles After Hyaluronic Acid Filler Injection
assess electrophysiological changes in some facial muscle dynamics following hyaluronic acid filler injection in superficial versus deep level of injection.
- Trial name
- NCT05034965
- Testing
- hyaluronic acid filler injection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Collagen Degeneration
Type I Collagen Fragments in the GCF and Saliva During OTM
Investigate the levels of type I Collagen fragments ICTP and CTX in GCF and saliva during initial leveling and alignment of the teeth in a sample of adolescents undergoing orthodontic treatment.
- Trial name
- NCT05020431
- Testing
- Biological measuring of collagen fragments biomarker during orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Urogenital Prolapse
Is Preoperative Urodynamics Essential for Women With Pelvic Organ Prolapse
urodynamic investigation when added in the diagnostic work-up of women with lower urinary tract dysfunction with POP is debatable.
- Trial name
- urodynaemics (NCT04980196)
- Testing
- urodynaemic studies
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University