Clinical trials: sponsored by Alexandria University
Craniofacial Abnormalities, Mandibular Hypoplasia
Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult Intubation
difficult problem in the paediatric age group because of their small mouth opening and un-cooperativeness.Currently used methods of sedation for fibreoptic intubation such as benzodiazepines, propofol or opioids may cause…
- Trial name
- NCT04426552
- Testing
- dexmedetomidine, sevoflurane
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Gastric Cancer
D2 Versus D1 Gastrectomy of Operable Gastric Cancer
Surgery is the mainstay treatment of operable gastric carcinoma but the optimal extent of lymph node (LN) dissection is controversial.
- Trial name
- NCT04429841
- Testing
- Radical gastrectomy with D1 lymphadenectomy, Radical gastrectomy with D2 lymphadenectomy
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Alexandria University
COVID-19
The Safety & Efficacy of Imatinib for the Treatment of SARS-COV-2 Induced Pneumonia
A randomized controlled pilot study on the safety \& efficacy of imatinib for the treatment of patient with moderate to severe SARS-COV-2 induced pneumonia.
- Trial name
- NCT04422678
- Testing
- Imatinib Mesylate, Standard of Care
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Alveolar Bone Loss
Evaluation of Short Implants' Success for Teeth Replacement in Atrophic Posterior Mandibular Ridge
The aim of this study was to evaluate clinically and radiographically the splinted short implants' and single short implants' stability and bone condition before and after loading, in atrophic posterior mandibular alveolar ridges.
- Trial name
- NCT04414709
- Testing
- Double short implant, Single short implant
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Dental Implant
Using Buccal Pad of Fat Free Tissue Transfer With Immediate Implant Placement
Implants placed immediately after tooth extraction usually present challenges in obtaining soft tissue coverage with high risk of bacterial invasion, wound dehiscence and subsequently adverse effect on the success rate of the…
- Trial name
- NCT04415619
- Testing
- Xenograft bone substitute (Osteo-biol)
- Volunteers
- 10 people
- Sponsor
- Alexandria University
COVID
Egyptian Initial Experience About 2019 Novel Corona Virus: Study of 48 Patients in Alexandria-Egypt Using Chest CT
Background: Corona virus disease 2019 (COVID-19) is a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT04382469
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Ventilation and Oxygenation, Obese; Positioning
Reverse Trendelenburg Position Versus Semi-recumbent Position in Obese Critically Ill Patients
The aim of this study is to assess the effect of reverse Trendelenburg position versus semi-recumbent position on ventilation and oxygenation parameters of obese critically ill patients
- Conditions
- Ventilation and Oxygenation, Obese; Positioning, Critically Ill
- Trial name
- NCT04376047
- Testing
- Reverse Trendelenburg position, Semi-recumbent position
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Alexandria University
Analgesia
Erector Spinae Plane Block in Pediatric Hip Surgery
Hip Surgery in pediatric patients is considered an extremely painful procedure. Managing pain in this surgery is challenging even with several available options, each with limitations.
- Trial name
- NCT04354571
- Testing
- Erector spinae plane block, caudal block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Nurse's Role
Virtual Reality Distraction Versus Positive Pre-Visit Imagery Intervention on Children's Dental Fear and Anxiety
Aim This study aimed to determine the effect of virtual reality distraction versus positive pre-visit imagery intervention on children's dental fear and anxiety during local anaesthesia injection. Research Hypotheses 1.
- Trial name
- NCT04348903
- Testing
- Virtual Reality Distraction, Positive Pre-Visit Imagery Intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Two Different Techniques to Perform Epidural Using Ultrasound
Accuro and the Use of Real Time Ultra Sound With Acoustic Puncture Assisted Device to Confirm Epidural Space End Point
Aim of the work: To compare the use of the Accuro ultrasound and a real time ultrasound guided epidural combined with the acoustic puncture assisted device to perform the epidural anesthesia Secondary aim is to compare the…
- Trial name
- NCT04204070
- Testing
- Accuro, APAD
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Bone Loss, Vertical Alveolar Bone Loss
Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
The purpose of the present research is to evaluate the effect of bioactive glass in bone regeneration immediately following extraction of mandibular and maxillary premolars.The hypothesis of the study assumes that this treatment…
- Conditions
- Bone Loss, Vertical Alveolar Bone Loss, Horizontal Alveolar Bone Loss
- Trial name
- NCT01878084
- Testing
- bioactive glass (sol-gel), empty extraction socket
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
RADICULAR CYSTS
Radicular Cyst Enucleation Using Piezosurgery Versus Conventional Surgery
AIM: The study was intended to evaluate the effectiveness of piezosurgery in enucleation of radicular odontogenic cysts in comparison to the conventional technique from both the clinical and radiographic perspectives.
- Trial name
- NCT04244422
- Testing
- PIEZOSURGERY VERSUS CONVENTIONAL SURGERY
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Zygomatic Arch Reduction
Reduction of Zygomatic Arch in Zygomaticomaxillary Fractures
To compare between ultrasound guided closed reduction and open reduction of zygomatic arch in cases of zygomaticomaxillary fracture. To evaluate the role of intra-operative ultrasound during zygomatic arch reduction.
- Trial name
- NCT04218058
- Testing
- reduction of zygomatic arch in zygomaticomaxillary complex fracture
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Ivabradine, Propranolol
Efficacy of Ivabradine Versus Propranolol Premedication During Hypotensive Anesthesia in Endoscopic Sinus Surgery
50 Patients, aged from 18 to 39 years, ASA physical status I and II, undergoing endoscopic sinus surgery will be enrolled in the study.The patients will be randomly allocated by simple randomization using a computer programme…
- Conditions
- Ivabradine, Propranolol, Hypotensive Anesthesia
- Trial name
- NCT04208594
- Testing
- Ivabradine, Propranolol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Stroke, Acute, Pulmonary Rehabilitation
Effect of Pulmonary Rehabilitation Program on Patients With Acute Ischemic Stroke, Mortality and Disability
Severe stroke remains an important cause of mortality and morbidity, despite advances in disease management, acute treatment and secondary measures.
- Conditions
- Stroke, Acute, Pulmonary Rehabilitation, Morality
- Trial name
- NCT04110652
- Testing
- pulmonary rehabilitation program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Postoperative Pain
Continuous Epidural Analgesia Versus Continuous Supra-Inguinal Fascia Iliaca Block in Total Hip Replacement Surgery
comparison of continuous epidural analgesia and ultrasound guided continuous supra-inguinal fascia iliaca compartment block after total hip replacement surgery
- Trial name
- S-FICB (NCT04196439)
- Testing
- continuous epidural analgesia, supra-inguinal fascia iliaca compartment block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Intravenous Cannulation
AccuVein AV400 Device Versus Ultrasound-guided Cannulation of the Great Saphenous Vein at the Ankle in Infants
Establishment of venousaccess in the age group ≤12 months can be difficult and associated with repetitive punctures . Numerous techniques to facilitate peripheral venous puncture have been described such as local warming…
- Trial name
- NCT04164862
- Testing
- AccuVein AV400 Device Versus Ultrasound-guided Cannulation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Mechanically Ventilated Patients
Effect Of Clustered Nursing Interventions On Physiological Response In Critically Ill Patients
To determine physiological responses related to clustered nursing interventions among critically ill patients.
- Trial name
- NCT04134481
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Skin Rejuvenation
Evaluation of the Efficacy and Tolerability of Autologous Adipose Tissue Derived Stem Cells on Facial Rejuvenation
This study is to evaluate the efficacy and tolerability of autologous adipose tissue derived stem cells in facial rejuvenation.
- Trial name
- NCT03928444
- Testing
- intradermal injection of adipose derived stem cells to one side of the face, intradermal injection of saline to one side of the face
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alexandria University