Clinical trials: sponsored by Alexandria University
Decision Making , Cesarean Section
The Impact of a Shared Decision-Making Intervention on Intraoperative Patient Experience During Elective Cesarean Delivery Under Spinal Anesthesia
Caesarean delivery (CD) is a common surgical procedure performed when vaginal delivery poses risks to the mother or fetus, with global rates projected to reach 28.5% by 2030.
- Trial name
- NCT07476482
- Testing
- Proactive Plan: prophylactic IV ketamine 0.2 mg/kg or IV midazolam 1 mg given prior to incision. Reactive Plan: no prophylactic medication; rescue IV fentanyl 50 mcg administered only if NRS ≥4., Control Group (Standard Care)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Shoulder Pain , Laparoscopic Cholecystectomy
The Impact of Saline Temperature and Local Anesthetic Adjuvants on Postoperative Shoulder Pain and Inflammatory Marker Levels Following Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy has become the gold standard for the operative treatment of gallbladder disease due to its minimally invasive nature and improved patient outcomes.
- Trial name
- NCT07450781
- Testing
- Room-temperature saline (25-30 ml/kg ) irrigation without local anesthetic., Room-temperature saline (25-30 ml/kg l) with local anesthetic ( 0.25% bupivacaine according to body weight)., Warm saline (37°C, 25-30 ml/kg ) irrigation without local anesthetic.
- Where
- Egypt
- Volunteers
- 216 people
- Sponsor
- Alexandria University
Electrocardiogram Interpretation, Nursing Education
Innovative Electrocardiogram Training Using Artificial Intelligence Clinical Scenarios for Nursing Staff
Background and Purpose Accurate interpretation of an Electrocardiogram is a vital skill for nursing staff to ensure patient safety and timely intervention in cardiovascular care.
- Conditions
- Electrocardiogram Interpretation, Nursing Education, Clinical Reasoning, Artificial Intelligence
- Trial name
- NCT07455357
- Testing
- Artificial Intelligence Driven Scenario-Based Learning Software, Traditional Electrocardiogram Educational Program
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Alveolar Bone Loss
Magnetic Mallet and Piezotome in Atrophic Anterior Maxillary Ridge Expansion With Simultaneous Bone Graft and Implant Placement (
Background: teeth loss in the anterior maxilla initiate residual ridge resorption, especially in the anterior region. The consequence of this resorption is a gradual medial or palatal shift of the crest of maxilla.
- Trial name
- NCT07467369
- Testing
- ridge expansion by magnetic mallet, ridge expansion by piezotome
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Pemphigus Vulgaris, Skin Erosion
Effect of Topical Insulin on Healing Rate of Pemphigus Lesions
This study investigates the efficacy of topical insulin in promoting healing of pemphigus vulgaris erosions. Twenty patients with pemphigus vulgaris were enrolled, each contributing three comparable lesions randomly allocated to…
- Conditions
- Pemphigus Vulgaris, Skin Erosion, Autoimmune Blistering Disease
- Trial name
- NCT07461103
- Testing
- insulin glargine, human insulin, 0.9% Normal Saline
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Dental Education
AI-Driven Digital Self-Assessment Framework for Preclinical Tooth Preparation
This study aims to compare traditional faculty-based assessment with two AI-assisted digital self-assessment software programs for evaluating tooth preparations for metal-ceramic crowns for undergraduate dental preclinical…
- Trial name
- NCT07462156
- Testing
- Non-metrology-grade digital group (NMG), metrology-grade digital group (MG), Traditional group (TG)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Sleeve Gastrectomy, Magnesium Sulfate
Effect of Adding Magnesium Sulphate to Bupivacaine in Laparoscopic Periportal Preperitoneal Local Infiltration in Laparoscopic Sleeve Gastrectomy
EFFECT OF ADDING MAGNESIUM SULPHATE TO BUPIVACAINE IN LAPAROSCOPIC PERIPORTAL PREPERITONEAL LOCAL INFILTRATION IN LAPAROSCOPIC SLEEVE GASTRECTOMY Our study shows that adding magnesium to the block will prolong duration of…
- Conditions
- Sleeve Gastrectomy, Magnesium Sulfate, Bupivacaine
- Trial name
- NCT07451327
- Testing
- ADDING MAGNESIUM SULPHATE TO BUPIVACAINE IN LAPAROSCOPIC PERIPORTAL PREPERITONEAL LOCAL INFILTRATION IN LAPAROSCOPIC SLEEVE GASTRECTOMY
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Alexandria University
Cleft Lip Palate, Class III Skeletal Malocclusion
Evaluation of Modified Le Fort I Osteotomy for Treating Cleft Lip and Palate Patients
Nine adults with Angle class III relation and persistent alveolar bone defect due to CL/P deformity were included. SLF-1 maxillary advancement was performed.
- Conditions
- Cleft Lip Palate, Class III Skeletal Malocclusion, Le Fort; I
- Trial name
- NCT07423806
- Testing
- segmental Le Fort I (SLF-1) osteotomy
- Where
- Egypt
- Volunteers
- 9 people
- Sponsor
- Alexandria University
Neonatal Sepsis
Chlorhexidine Gluconate and Alcohol Hand Rubbing on Healthcare-associated Infection
This study aims to compare of effect of chlorhexidine gluconate and alcohol hand rubbing on healthcare-associated infection (HCAI) in neonatal intensive care unit at Alexandria University Children Hospital.
- Trial name
- NCT07421323
- Testing
- Alcohol hand rub group, Chlorhexidine hand rub
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Dental Pain
Technology-based Distraction Techniques in Managing Children With Attention-deficit/Hyperactivity Disorder
The present study aims to assess and compare the effectiveness of different technology-based distraction techniques on pain perception and dental anxiety in children with Attention Deficit/Hyperactivity Disorder during different…
- Trial name
- NCT07411157
- Testing
- Virtual reality glasses, White noise, Basic behavior management techniques
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Condylar Fractures
Retromandibular Transparotid Approach Versus Transmasseteric Anteroparotid Approach for Fixation of Subcondylar Fracture
Background: Condylar fracture is one of mandibular fracture which accounts for 20-35%. It is the most controversial fractures regarding diagnosis and management.
- Trial name
- NCT07403708
- Testing
- transmasseteric anteroparotid approach, transparotid approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Mandibular Fracture, Virtual Plan of Mandibular Fracture
Evaluation of the Accuracy of 3d Printed Reduction Guide in Treatment of Mandibular Fractures Using Two Different Methods of Virtual Planning
This study will evaluate the accuracy of the use of 3-D printed reduction guide in treatment of mandibular fractures using two different methods of virtual planning.
- Trial name
- NCT07385924
- Testing
- Mandibular fracture treatment by 3d printed guide where virtual planning will be done using the manual reduction technique., Mandibular fracture treatment by 3d printed guide where virtual planning will be done using the mirror image reduction technique.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Periodontitis, Diabete Mellitus
Omega-3 Pufa and Aspirin as Adjunctive Therapy in Treatment of Smoker Patients With Stage Iii Periodontitis
Background: Smoking reduces the effect of non-surgical periodontal therapy, a host modulation regimen consisting of omega-3 polyunsaturated fatty acids (ω-3 PUFA) supplementation with low-dose aspirin (ASA) with or without…
- Trial name
- NCT07385300
- Testing
- Omega-3 PUFA and Aspirin as adjunctive therapy to (SRP), Omega-3 PUFA and Aspirin and doxycycline as adjunctive therapy to (SRP), scaling and root planning (SRP)
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
End Stage Kidney Disease (ESRD)
Optimizing Hemodialysis: How Low Dialysate Flow Alters Adequacy and Patient Recovery.
The goal of this clinical trial is to detect if lower dialysate flow rate can affect hemodialysis adequacy , dialysis recovery time and patients quality of life.
- Trial name
- NCT07360769
- Testing
- lower dialysate flow rate ( 300ml/min). then testing its effect on hemodialysis adequacy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
- Trial name
- NCT07356908
- Testing
- polysomnography
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Post Operative Pain
Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides
General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique.
- Trial name
- NCT07357233
- Testing
- Manual-less, Conventional technique
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Anxiety
Inhaled Lavender Oil, Rosemary Oil, and Their Combination in Reducing Dental Anxiety and Pain in Pediatric Dental Patients
Background: Dental anxiety and pain are common concerns in pediatric dentistry. These issues can lead to negative experiences for children and can make it difficult for them to cooperate during treatment.
- Trial name
- NCT07352397
- Testing
- Lavender group, Rosemary group, Combination of both lavender and rosemary
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
TMD
Two Treatment Modalities for Myogenous Temporomandibular Disorders
Temporomandibular disorder (TMD) is a common condition with multifactorial etiology, including trauma, emotional stress, parafunctional habits, and occlusal discrepancies.
- Trial name
- NCT07351812
- Testing
- Stabilization Appliance, Ear Stent
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Alexandria University
Premature, Feeding Disorders
Effect OF Lactase Enzyme Supplements ON Intolerance IN Preterm Neonates
This study aims to study the effect of lactase enzyme in preventing feeding intolerance in preterm neonates in neonatal intensive care unit at Alexandria University Children's Hospital.
- Conditions
- Premature, Feeding Disorders, Lactase Deficiency, Congenital
- Trial name
- NCT07088302
- Testing
- lactase administration
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Premature, Placental Transfusion
Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications and Effect on Their Hematological Profile
The objective of this study is to evaluate the general course and prognosis associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking and delayed cord clamping) in…
- Trial name
- NCT06812507
- Testing
- intact umbilical milking, cut umbilical milking, Delayed cord clamping
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Alexandria University