Clinical trials: sponsored by Alexandria University
Sarcoidosis Lung
Sarcoidosis Immunotsuppressive Therapy and Lymphoma Development
Impact of Immunosuppressive Therapy for Sarcoidosis on Lymphoma Development
- Trial name
- NCT07343401
- Testing
- lymph node biopsy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Caries Active
Bioceramic Putty Versus MTA in Pulpotomized Primary Teeth to be Covered With 3D Printed Resin Crowns Versus Stainless Steel Crown
children aged 5 to 7 years with deep carious second primary molars that require vital pulp therapy will be treated using either MTA or bioceramic putty, then will be fully covered using either stainless steel crowns or 3D printed…
- Trial name
- NCT07344038
- Testing
- Endo-sequence bioceramic putty pulpotomy, Bio MTA+ pulpotomy, Stainless Steel Crowns (SSCs)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Immediate Implant, Vestibular Socket Therapy
Immediate Implant Placement in Type ii Socket by Vestibular Socket Therapy Using Collagen Membrane
Background: Immediate implant placement has become a routine and regular clinical practice. When the labial bone plate develops a dehiscence-type defect, delayed implant placement was recommended to give suitable amount of time…
- Conditions
- Immediate Implant, Vestibular Socket Therapy, Type II Socket
- Trial name
- NCT07337837
- Testing
- vestibular socket therapy, open flap surgery
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Alexandria University
Oral Leukoplakia
Efficacy of Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia Treatment
Oral leukoplakia (OL) is recognized as the most common potentially malignant disorder of the oral mucosa. The pathogenesis of OL is complex and multifactorial, with oxidative stress playing a central role.
- Trial name
- NCT07331935
- Testing
- Coenzyme Q10 gel, Topical curcumin gel
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Alexandria University
Bariatric Surgery, Lidocaine
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours.
- Conditions
- Bariatric Surgery, Lidocaine, Dexmedetomidine
- Trial name
- NCT07327905
- Testing
- intravenous lidocaine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Palatal Lesion
Ozonated Gel and Titanium Platelet-rich Fibrin (on Palatal Wound Healing
Background: autogenous soft tissue grafts can be considered the gold standard for treatment of mucogingival problems. The most common site for harvesting the graft is the palate.
- Trial name
- NCT07320391
- Testing
- Ozonated Gel Application, T-PRF Application, Conventional treatment
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Alexandria University
Temporomandibular Joint Ankylosis
Patient-Specific Guides for Gap Pediatric Arthroplasty
To date, few reports have combined patient-specific guides with piezoelectric devices for gap arthroplasty in children. This study evaluates the feasibility, accuracy, and early outcomes of this approach, hypothesizing that the…
- Trial name
- NCT07320911
- Testing
- Patient-Specific Narrow-Slit Osteotomy Guides
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Alexandria University
Mandibular Resection, Mandibular Reconstruction* / Methods
Patient-specific Reconstruction Plate for Segmental Mandibular Defects
The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require…
- Conditions
- Mandibular Resection, Mandibular Reconstruction* / Methods, Mandibular Reconstruction
- Trial name
- NCT07320924
- Testing
- Patient specific reconstruction plate
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Alexandria University
Orbital Fractures, Zygomatic Fractures
Modified Anatomical Mesh In The Management Of Orbito-Zygomatico-Maxillary Complex Fractures
Orbito-Zygomaticomaxillary-complex fractures is a form of a complex orbital floor fracture, with affection of the inferior orbital rim and the orbital walls.
- Trial name
- NCT06958510
- Testing
- 3D-Modified Anatomical-Mesh., conventional orbital rim miniplates and orbital mesh configuration
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Apical Periodontitis
N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis
A randomized controlled trial comparing the postoperative pain intensity, periapical biomarkers level, and periapical healing in patients with necrotic mature teeth and apical periodontitis treated with N-acetylcysteine (NAC), as…
- Trial name
- NAC (NCT07262554)
- Testing
- Calcium hydroxide (Ca(OH)₂), N-Acetylcysteine (NAC)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Impacted Mandibular Third Molar
Efficacy of Er:YAG Laser in Removing Impacted Mandibular Third Molars
This randomized controlled clinical trial aims to evaluate the efficacy of the Er:YAG laser in the removal of impacted mandibular third molars compared to the conventional surgical technique.
- Trial name
- NCT07297043
- Testing
- Er:YAG laser, Conventional Rotary Instruments Surgery
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Postoperative Outcome, Whipple Procedures
Veno-arterial CO2 Pressure Difference to Arterio-venous O2 Difference Ratio & Blood Lactate Levels Are Predictors of Postoperative Outcome in Whipple Procedures
Whipple surgery is a complex abdominal procedure associated with a high risk of hemodynamic instability and splanchnic hypoperfusion leading to anastomotic leaks, delayed gastric emptying, and organ dysfunction Traditional…
- Trial name
- NCT07306845
- Testing
- predictors of postoperative outcome in Whipple Procedures
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Temporomandibular Disorder (TMD), Internal Derangement
Computer Guided Single Needle Arthrocentesis
The intra-articular injection is considered the first line of minimally invasive treatment in temporomandibular joint with internal derangement (TMJ-ID) patients who do not respond to conservative treatment.
- Conditions
- Temporomandibular Disorder (TMD), Internal Derangement, Anterior Disc Displacement
- Trial name
- NCT07306936
- Testing
- Computer-guided single needle arthrocentesis, conventional free hand single needle arthrocentesis
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Ameloblastoma
Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin
Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP).
- Trial name
- NCT07306962
- Testing
- Virtual lesion segmentation for mandibular ameloblastoma
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Alexandria University
BioFlex Crowns Using Hall Technique
Evaluation of Bioflex Crowns Using the Hall Technique in Primary Molars
The goal of this randomized controlled clinical trial is to to evaluate the clinical performance and radiographic success of BioFlex crowns versus SSCs using Hall Technique in primary dentition.
- Trial name
- NCT06847646
- Testing
- bioflex crown using hall technique, stainless steel crown using hall technique
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Alexandria University
Topical Anaesthesia, General Anesthetic Drug Adverse Reaction
Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Versus General Anesthesia
Comparison between cataract surgery under local versus general anesthesia regarding postoperative pain, complications and patient satisfaction and need for rescue analgesic intake after surgery The results will be followed up at…
- Conditions
- Topical Anaesthesia, General Anesthetic Drug Adverse Reaction, Cataract
- Trial name
- NCT07287683
- Testing
- Topical Anaesthesia group, General Anaesthesia group
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Piezotome, Implant-supported Single Crowns
Piezotome Atraumatic Tooth Extraction And Immediate Implant Placement In Maxillary Anterior Region
Tooth extraction is critical for dental treatment complications followed by immediate implant placement to restore the extracted tooth .
- Trial name
- NCT07041879
- Testing
- maxillary anterior teeth atraumatically extracted with piezotome extraction kit, and subsequent immediate implant placement, maxillary anterior teeth atraumatically extracted with periotome, and subsequent immediate implant placment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Fast-track Protocol, Hip Fracture
IMPLICATION OF FAST-TRACK PROTOCOL FOR HIP FRACTURE FIXATION IN ALEXANDRIA UNIVERSITY HOSPITALS
The present study aims to evaluate the impact of fast-track protocol of hip fracture fixation within 48 hours on patients' mortality and morbidities.
- Conditions
- Fast-track Protocol, Hip Fracture, 30 Days Mortality
- Trial name
- NCT06881121
- Testing
- Fast-track protocol for hip fracture fixation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Local Analgesia Via Infiltration, Caudal Epidural Anesthesia
Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery
The goal of this prospective study is to is to evaluate the perioperative pain management of Erector Spinae Block versus Caudal Block using the Face, Legs, Activity, Cry, Conceal ability (FLACC) Pain Scale inn children aged 2 to…
- Conditions
- Local Analgesia Via Infiltration, Caudal Epidural Anesthesia, Caudal Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07281235
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block, Caudal Block Anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Post-extraction Pain (PEP), Wound Healing
Effect of Low-Level Laser Therapy on Wound Healing and Post-extraction Pain Management of Primary Molars.
The goal of this clinical trial is to evaluate the effect of low-level laser therapy on wound healing of primary molar teeth extraction. in children aged 5-8 years with bilateral primary molars indicated for extraction.
- Trial name
- NCT07033403
- Testing
- Low Level Laser Therapy
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Alexandria University