Clinical trials: sponsored by Anhui Medical University
Ulcerative Colitis (UC)
Alpha-0261 Tablets for Moderate-to-Severe Ulcerative Colitis
The purpose of this protocol is to evaluate the safety and efficacy of Alpha-0261 in participants with moderately to severely active ulcerative colitis.
- Trial name
- NCT07744646
- Testing
- Alpha-0261
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Chronic Subdural Hematoma
Frontal vs Parietal Eminence Drainage for Chronic Subdural Hematoma
This clinical trial aims to find out whether the puncture site used during minimally invasive surgery with twist-drill puncture and closed-system drainage affects the treatment of chronic subdural hematoma (cSDH).
- Trial name
- NCT07731620
- Testing
- Frontal-region puncture drainage, Parietal Eminence region puncture drainage
- Where
- 3 sites in China
- Volunteers
- 440 people
- Sponsor
- The Second Hospital of Anhui Medical University
Problematic Screen Use in Preschool Children, Anxiety Symptoms in Preschool Children
Effects of an SMS-Based Parenting Intervention on Anxiety Symptoms in Preschool Children
Excessive screen use and anxiety symptoms in preschool children have become increasingly prominent public health problems. This randomized controlled trial aims to determine whether, compared with a control group, an ecological…
- Conditions
- Problematic Screen Use in Preschool Children, Anxiety Symptoms in Preschool Children, Social-emotional Behavior Problems in Preschool Children
- Trial name
- NCT07728344
- Testing
- Ecological Momentary Parenting Intervention, General Pediatric Health Education
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Chronic Subdural Hematoma
Template-Guided Burr-Hole Drainage With Middle Meningeal Artery Coagulation for Chronic Subdural Hematoma
Chronic subdural hematoma is a collection of blood and fluid on the surface of the brain that is common in older adults. Burr-hole drainage is a standard surgical treatment, but the hematoma may come back in some patients and…
- Trial name
- 3D-MMA-cSDH Tr (NCT07720687)
- Testing
- Standard Burr-Hole Drainage Group, 3D-Printed Template-Guided Burr-Hole Drainage With Attempted MMA Coagulation Group
- Where
- China
- Volunteers
- 440 people
- Sponsor
- The Second Hospital of Anhui Medical University
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Major Depressive Disorder (MDD)
Investigating Functional Changes in the Frontotemporal Cortex of Patients With Major Depressive Disorder Following Electroconvulsive Therapy or Magnetic Seizure Therapy Using Functional Near-infrared Spectroscopy (fNIRS)
Against the clinical backdrop of the growing global burden of neuropsychiatric disorders, the rapid rise in depression prevalence, and the frequent association of these conditions with cognitive impairment, this study highlights…
- Trial name
- NCT07533773
- Testing
- Electroconvulsive Therapy, Magnetic Seizure Therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Post-stroke Aphasia
Efficacy and Neural Mechanisms of Transcranial Direct Current Stimulation Targeting the Supplementary Motor Area for the Treatment of Subacute Post-stroke Aphasia
This study aims to investigate the efficacy of transcranial direct current stimulation (tDCS) in patients with post-stroke aphasia (PSA) and to explore its potential neural mechanisms.
- Trial name
- NCT07700537
- Testing
- transcranial direct current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Electroconvulsive Therapy, Major Depressive Disorder
Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy
To compare the efficacy and tolerability of Electroconvulsive Therapy (ECT) and Magnetic Seizure Therapy (MST) in patients with major depressive disorder (MDD).
- Conditions
- Electroconvulsive Therapy, Major Depressive Disorder, Magnetic Seizure Therapy
- Trial name
- NCT07473648
- Testing
- Electroconvulsive Therapy, Magnetic Seizure Therapy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Mild Cognitive Impairment (MCI)
Non-pharmacological Interventions for People With Mild Cognitive Impairment in the Community
Mild cognitive impairment (MCI) may increase the risk of dementia. This study will evaluate an 8-week community-family mutual support intervention for adults aged 60 years or older with MCI.
- Trial name
- CNPI-MCI (NCT07703267)
- Testing
- Community-Family Mutual Support Intervention, Routine Community Care
- Volunteers
- 70 people
- Sponsor
- Anhui Medical University
Obesity, Diabetes Mellitus, Type 2
AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes
This multicenter randomized controlled trial will evaluate whether an AI-assisted intensive lifestyle intervention can improve weight and glycemic management in adults with obesity and newly diagnosed type 2 diabetes, compared…
- Trial name
- AI-LIFE-T2D-OB (NCT07697391)
- Testing
- AI-Assisted Intensive Lifestyle Intervention, Tirzepatide, Standard Lifestyle Management
- Where
- 2 sites in China
- Volunteers
- 285 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Magnetic Stimulation, Behavioral and Psychological Symptoms in Alzheimer's Disease
Network-Guided Individualized TMS for BPSD in Alzheimer's Disease: A Double-blind Randomized Controlled Trial
Evaluate the safety and efficacy of personalized network-guided transcranial magnetic stimulation for treating behavioral and psychological symptoms in patients with Alzheimer's disease.
- Conditions
- Transcranial Magnetic Stimulation, Behavioral and Psychological Symptoms in Alzheimer's Disease, Individualized Navigation
- Trial name
- NET-BPSD (NCT07692542)
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Attention, Healthy Volunteers
The Impact of One-Year Boxing Training on Attention in Adolescent Athletes
This study focuses on adolescent boxing athletes as the research subjects, employing the Attention Network Test to systematically investigate the effects of one-year boxing training on the attentional functions of adolescent…
- Trial name
- NCT07688616
- Testing
- Boxing Group, Control Group
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
End-Stage Kidney Disease (ESKD), Maintenance Hemodialysis (MHD)
Health Coaching for Self-Management in Maintenance Hemodialysis Patients
This study is a quasi-experimental study designed to evaluate the effects of a health coaching intervention on self-management ability in patients undergoing maintenance hemodialysis.
- Trial name
- NCT07685626
- Testing
- Health Coaching, Routine Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Systemic Lupus Erythematosus (SLE), Visual Function
Study on Early Visual Dysfunction in Patients With Systemic Lupus Erythematosus
OCT, OCTA, fundus photography, and fundus autofluorescence ( FAF ) were used to observe the fundus physiological indexes of normal subjects and SLE patients, to explore the differences of subclinical retinal damage in SLE…
- Trial name
- NCT07679776
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
T2DM (Type 2 Diabetes Mellitus)
Anti-inflammatory Dietary Intervention in Patients With Type 2 Diabetes: A Randomized Controlled Trial
The goal of this clinical trial is to evaluate whether an evidence-based anti-inflammatory dietary intervention can reduce inflammation and improve glycemic control in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT07656805
- Testing
- Anti-inflammatory Dietary Intervention, Standard Diabetes Dietary Advice
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Anhui Medical University
Alzheimer's Disease, Transcranial Magnetic Stimulation
Safty and Efficacy of MCI Network Guided TMS for Early Alzheimer's Disease: A Randomized, Double-blind Trial
Estimate the safty and efficacy of personalized network neuronavigated transcranial magnetic stimulations in early Alzheimer's disease patients
- Conditions
- Alzheimer's Disease, Transcranial Magnetic Stimulation, Individualized Navigation
- Trial name
- SENS-eAD (NCT07138677)
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Thyroidectomy, Coughing Reflex
The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Non-inflatable Transoral Endoscopic Thyroid Surgery
This study intends to implement esketamine-assisted anesthesia in patients undergoing non-inflatable transoral endoscopic thyroidectomy through a prospective randomized controlled trial, in order to observe the effect of…
- Trial name
- NCT07641673
- Testing
- Esketamine（iv）, ESK spray, Normal Saline
- Where
- China
- Volunteers
- 186 people
- Sponsor
- The Second Hospital of Anhui Medical University
Thyroidectomy, Coughing Reflex
The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Open Thyroid Surgery
This study intends to conduct a prospective randomized controlled trial to implement esketamine-assisted anesthesia in patients undergoing open thyroidectomy, in order to observe the effect of esketamine on coughing during…
- Trial name
- NCT07625826
- Testing
- Esketamine, Normal Saline
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Second Hospital of Anhui Medical University
Insomnia
Effects of Aromatherapy on Sleep Quality in Hospitalized Elderly Female Patients With Insomnia
To evaluate the efficacy and safety of standardized aromatherapy compared with placebo in improving sleep quality among hospitalized elderly female patients with insomnia.
- Trial name
- NCT07373132
- Testing
- Aromatherapy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Academic Self-efficacy
Classroom Physical Activity in University Students
The goal of this study is to learn if a classroom-based physical activity program can improve academic self-efficacy in university students.
- Trial name
- NCT07594457
- Testing
- classroom based physical activity with Instructional videos
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University