Clinical trials: sponsored by Anhui Medical University
Academic Self-efficacy
Classroom Physical Activity in University Students
The goal of this study is to learn if a classroom-based physical activity program can improve academic self-efficacy in university students.
- Trial name
- NCT07594457
- Testing
- classroom based physical activity with Instructional videos
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Depression
Transcranial Direct Current Stimulation for Depression
Background: Depression is a common mental disorder characterized by persistent low mood and anhedonia. Pharmacological and psychotherapeutic treatments demonstrate only moderate efficacy.
- Trial name
- NCT07500064
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Second Hospital of Anhui Medical University
CHF - Congestive Heart Failure
A Prospective, Randomized, Blind, Controlled Multicenter Clinical Study Comparing the Effectiveness of Preventive Ventricular Arrhythmia Ablation on the Prognosis After Left Ventricular Assist Device (LVAD) Surgery.
To compare the preventive effect of preventive ventricular arrhythmia ablation on the composite events 30 days after surgery in the study population.
- Trial name
- PAVA-LVAD (NCT07589738)
- Testing
- preventive ablation group
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Temporal Interference Stimulation, Non Suicidal Self Injury
TIS for NSSI in Adolescent Depression
Temporal Interference Stimulation (TIS) has been successfully used to help patients with depression. However, its role in alleviating self injuries remained uncertain.
- Conditions
- Temporal Interference Stimulation, Non Suicidal Self Injury, Major Depressive Disorder
- Trial name
- NCT07554755
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Anhui Medical University
Stroke, Cerebrovascular Disorders
Intra-arterial Thrombolysis for Acute Ischemic Stroke With Medium Vessel Occlusion
Acute ischemic stroke (AIS) due to medium vessel occlusion (MeVO) or severe stenosis poses a significant clinical challenge. Recent large randomized controlled trials, DISTAL and ESCAPE-MeVO, demonstrated no significant benefit…
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Nervous System Diseases
- Trial name
- RESCUE MeVO (NCT07185022)
- Testing
- Intra-arterial Thrombolysis, Best Medical Treatment
- Where
- 6 sites in China
- Volunteers
- 282 people
- Sponsor
- The Second Hospital of Anhui Medical University
AIHA - Warm Autoimmune Hemolytic Anemia, UCART
UCAR T-cell Therapy Targeting CD19/BCMA in Relapsed/Refractory Autoimmune Hemolytic Anemia
This is an investigator-initiated trial to evaluate the safety and efficacy of universal allogeneic anti-CD19/BCMA CAR T-cells in AIHA who have failed ≥ 3 lines of therapy
- Trial name
- NCT07530380
- Testing
- QT-219C Cell Injection
- Where
- China
- Volunteers
- 15 people
- Sponsor
- The Second Hospital of Anhui Medical University
Post-stroke Aphasia
Clinical Study on the Safety and Efficacy of Temporal Interference Stimulation in the Treatment of Post-Stroke Aphasia
Neurological disorders encompass a wide variety of diseases, including congenital and neurodevelopmental disorders, cerebrovascular and neurodegenerative diseases, nervous system infections, neuroimmune diseases, neuromuscular or…
- Trial name
- NCT07346378
- Testing
- temporal interference stimulation, speech and language therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Depressive Disorder, Temporal Interference Stimulation
Intervention Effect of Temporal Interference Stimulation (TIS) on Depressive Disorder
To investigate the effect of Temporal Interference Stimulation (TIS) on associative memory (AM) in patients with depressive disorder
- Trial name
- NCT07191392
- Testing
- Temporal Interference Stimulation (TIS)
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Generalized Anxiety Disorder
Mapsd Dual-target cTBS (Auditory Cortex and M1) for Generalized Anxiety Disorder
The purpose of this study is to investigate the effectiveness of a dual-target non-invasive brain stimulation technique called continuous Theta Burst Stimulation (cTBS) for treating Generalized Anxiety Disorder (GAD).
- Trial name
- Dual-ACM1-GAD (NCT07403591)
- Testing
- Active Dual-target cTBS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Malignant Obstructive Jaundice
Comparison of Two Seed Strand Implantation Techniques for Biliary Cancer
This study aimed to compare the safety and effectiveness of two different methods for fabricating and implanting Iodine-125 (^125^I) radioactive seed strands combined with a metal stent for treating malignant obstructive…
- Trial name
- NCT07381439
- Testing
- Percutaneous transhepatic biliary stenting with conventional linear ^125^I seeds strand, Percutaneous transhepatic biliary stenting with novel spiral ^125^I seeds strand
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Alternating Current Stimulation, Depressive Disorder
Intervention Effect of High Definition Transcranial Alternating Current Stimulation (HD-tACS) on Depressive Disorder
To investigate the intervention effect of high definition transcranial alternating current stimulation (HD-tACS) on suicidal ideation in patients with depressive disorder and its underlying neural mechanism by magnetic resonance…
- Trial name
- NCT05932706
- Testing
- High definition transcranial alternating current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Antenatal Depression, Antenatal Anxiety
Effectiveness and Cost-effectiveness of Simultaneous Screening and Intervention for Antenatal Depression and Anxiety Symptoms From a Transdiagnostic Perspective: A Scale-up Feasibility Study
This scale-up study aimed to explore the effectiveness of simultaneous screening and intervention of antenatal depression and anxiety in preventing postpartum depression and anxiety and how scale-up might be successfully…
- Trial name
- NCT07349368
- Testing
- implementation group
- Where
- China
- Volunteers
- 3,314 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Non Small Cell Lung Cancer, Immune Checkpoint Inhibitors
Impact of Pretreatment Emotional Distress on Survival and the Predictive Role of Peripheral Biomarkers in Immunotherapy Response Among Gastroesophageal and Lung Cancer Patients
This is the prospective, observational cohort study to explore the impact of pretreatment emotional distress on survival and the predictive role of peripheral blood metabolic and inflammatory markers in immunotherapy response…
- Conditions
- Non Small Cell Lung Cancer, Immune Checkpoint Inhibitors, Inflammation, Cancer, Treatment-Related
- Trial name
- NCT06629714
- Testing
- Exposure: emotional distress status
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Anhui Medical University
Transcranial Direct Current Stimulation, Functional Magnetic Resonance Imaging
Intervention Effect of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on Depressive Disorder
To investigate the intervention effect of high definition transcranial direct current stimulation (HD-tDCS) on somatic symptoms in patients with depressive disorder and its underlying neural mechanism by MRI.
- Conditions
- Transcranial Direct Current Stimulation, Functional Magnetic Resonance Imaging, Depressive Disorder
- Trial name
- NCT05286645
- Testing
- High definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Anhui Medical University
MRD, Prostate Cancer
Minimal Residual Disease Used in Predicting Therapeutic Efficacy in Metastatic Hormone-sensitive Prostate Cancer
This study is a prospective, single-center, observational study of patients with newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC).
- Conditions
- MRD, Prostate Cancer, mHSPC
- Trial name
- NCT07112612
- Volunteers
- 50 people
- Sponsor
- Anhui Medical University
Generalized Anxiety Disorder
Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder
A placebo-controlled superiority design was used to evaluate the efficacy of 40 mg/ day of Crisugabalin capsules in the treatment of GAD.
- Trial name
- CEASE-GAD (NCT07330648)
- Testing
- Crisugabalin 20mg bid, Venlafaxine-XR 75mg bid, Crisugabalin capsules mimic 0mg/capsule bid
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Anhui Medical University
Prostate Cancer, Lymph Node Cancer Metastatic
Study of Predicting Lymph Node Metastasis of High-risk Prostate Cancer by Artificial Intelligence Multi-omics Analysis
The pathological-omics and imaging-omics in this study are combined to construct an artificial intelligence (AI) model that can predict whether high-risk prostate cancer patients may have lymph node metastasis.
- Conditions
- Prostate Cancer, Lymph Node Cancer Metastatic, Artificial Intelligence (AI)
- Trial name
- NCT07112599
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Anhui Medical University
Schizophrenia, Transcranial Magnetic Stimulation
Personalized iTBS in Real-World Clinical Settings for Schizophrenia
This study is designed to determine whether neuronavigation-guided, personalized Intermittent Theta-Burst Stimulation (iTBS) can produce clinically benefits for patients with schizophrenia when delivered in real-world treatment…
- Trial name
- EPSREAL-SC (NCT07176468)
- Testing
- Neuronavigation-guided individualized iTBS
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Parkinson Disease, Apathy
A Randomized Double-Blind Active-Controlled Crossover Trial of Respiratory-Gated Versus Non-Gated Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Motor and Non-Motor Symptoms in Parkinson's Disease
The goal of this clinical trial is to compare the effects of different modes and frequencies of transcutaneous auricular vagus nerve stimulation (taVNS) on motor and non-motor symptoms in people with Parkinson's disease.
- Conditions
- Parkinson Disease, Apathy, Sleep Disorder, Motor Disorders
- Trial name
- NCT06642454
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Anhui Medical University