Clinical trials: sponsored by Anhui Medical University
Acute Myocardial Infarction
Stellate Ganglion Morphine Infiltration on Myocardial Ischemia-Reperfusion Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion injury in AMI patients.
- Trial name
- tSGM-AMI (NCT06947135)
- Testing
- Morphine
- Where
- 3 sites in China
- Volunteers
- 166 people
- Sponsor
- The Second Hospital of Anhui Medical University
Artificial Intelligence, Colonoscopy
Real-time Feedback of Red-out Within Colonoscopy Intubation
This study will employ a prospective, multicenter, controlled design. It will be conducted across multiple centers, with participated centers randomly assigned to one of four groups: Group A, Group B, Group C, and Group D.
- Conditions
- Artificial Intelligence, Colonoscopy, Real-time Feedback
- Trial name
- NCT07273890
- Testing
- AI system
- Volunteers
- 576 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Post-ERCP Pancreatitis
Dose-escalation of Rectal Indomethacin for Preventing PEP
Our aim is to compare the efficacy of 100 mg versus 200 mg rectal indometacin in preventing post-ERCP pancreatitis (PEP) among high-risk patients without no pancreatic stenting.
- Trial name
- NCT07247682
- Testing
- standard-dose group VS high-dose group
- Where
- China
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Pathological Complete Response, Rectal Cancer
Clinical Study on the Safety and Relationship of Sintilimab Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma
This study is designed as a single-center, phase II exploratory clinical trial to evaluate the pathological response rate and safety of sintilimab (PD-1 inhibitor) combined with XELOX regimen (oxaliplatin + capecitabine) for…
- Conditions
- Pathological Complete Response, Rectal Cancer, Neoadjuvant Chemoimmunotherapy
- Trial name
- NCT07127497
- Testing
- Sintilimab combined with XELOX
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Magnetic Stimulation, Freezing of Gait
Dual-target, High-dose TMS for PD Patients With FOG
The aim of the current study was to verify whether high-dose TMS treatment of the motor and cognitive cortices is more effective in alleviating FOG than conventional-dose TMS of the motor cortex only.
- Trial name
- NCT05625386
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Anhui Medical University
Transcranial Magnetic Stimulation, Freezing of Gait
Effect of Theta-Burst Transcranial Magnetic Stimulation (TBS) for Freezing of Gait
To investigate the treatment effect of Theta-burst Transcranial Magnetic Stimulation (TBS) on patients with freezing of gait (FOG) and the underlying neural mechanism.
- Trial name
- NCT05192759
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Parkinson Disease, Apathy
Respiratory-gated Transcutaneous Auricular Vagus Nerve Stimulation for Improving Apathy in Parkinson's Disease
The goal of this clinical trial is to learn whether 100HZ respiratory-gated vagus nerve stimulation (RAVANS) can improve the non-motor symptoms in people with Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Apathy, Non-motor Symptoms, Vagus Nerve Stimulation
- Trial name
- NCT07118956
- Testing
- Active RAVANS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Intracranial Atherosclerosis, Cognitive Impairment
Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study
The purpose of this study is to explore the mechanism of cognitive impairment in patients with symptomatic intracranial atherosclerotic stenosis (ICAS), and further plans to explore the impact of different treatment options on…
- Conditions
- Intracranial Atherosclerosis, Cognitive Impairment, Cerebrovascular Event
- Trial name
- NCT06336174
- Testing
- Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin, Endovascular therapy,Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Anhui Medical University
Cardiometabolic Risk Factors
Effect of Vitamin D on Cardiovascular Metabolic Risk in Overweight/Obesity Adolescents in China
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency.
- Trial name
- NCT07053657
- Testing
- Dietary Supplement: Vitamin D3
- Where
- 2 sites in China
- Volunteers
- 130 people
- Sponsor
- Anhui Medical University
Adenotonsillar Hypertrophy
Remiazolam vs Propofol Total Intravenous Anesthesia on Postoperative Neurodevelopment After General Anesthesia in Children
The goal of this clinical trial is to learn the effects of remimazolam for total intravenous anesthesia on the neurodevelopment of children aged 3-6 years who underwent tonsil/adenoid removal surgery after general anesthesia when…
- Trial name
- REMPPON (NCT07194109)
- Testing
- Remimazolam based total intravenous anesthesia, Propofol based general anesthesia
- Volunteers
- 558 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Acute Promyelocytic Leukemia (APL)
Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia
This study aims to evaluate the safety and effectiveness of combining venetoclax with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) in patients with newly diagnosed acute promyelocytic leukemia (APL) who have very…
- Trial name
- NCT07187505
- Testing
- Venetoclax, All-trans retinoic acid, Arsenic Trioxide (ATO)
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Anhui Medical University
Metastatic Hormone-Sensitive Prostate Cance
A Novel Insight Into CRPC Progression and Immune: Evidence From Single-cell Spatial Transcriptome Multi-omics
This study will follow patients with metastatic hormone-sensitive prostate cancer (mHSPC) who receive androgen deprivation therapy (ADT) combined with different treatments.
- Trial name
- NCT07154914
- Testing
- Abiraterone + ADT
- Volunteers
- 396 people
- Sponsor
- Anhui Medical University
Depression Disorders, Non-suicidal Self-injury
The Impact of Beta-band Transcranial Alternating Current Stimulation (tACS) on Impulse Inhibition in Adolescents With Non-suicidal Self-injury
This clinical trial aims to determine whether beta-band transcranial alternating current stimulation (tACS) can improve impulse inhibition in adolescents with non-suicidal self-injury (NSSI) and to evaluate its safety.
- Trial name
- NCT07152925
- Testing
- Beta-frequency transcranial alternating current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Anxiety, Transcranial Magnetic Stimulation Repetitive
Neuroimage-guided Dual-target Continuous Theta Burst Stimulation for Generalized Anxiety Disorder
The aim of this clinical trial was to determine whether image-guided dual-target cTBS is effective for anxiety disorders. The main questions it aims to answer are: 1. Does dual-target cTBS improve patients' anxiety symptoms? 2.
- Trial name
- NCT06699706
- Testing
- Continuous theta-burst stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Malignant Tumors, Positron-Emission Tomography
FAP PET/CT or PET/MR Production in the Diagnosis, Staging, and Efficacy Assessment of Malignant Tumors Application
This clinical trial aims to investigate the value of fibroblast activation protein PET/CT(PET/MR) in the diagnosis, staging, and evaluation of treatment outcomes in malignant tumors.
- Trial name
- NCT06270394
- Testing
- 68Ga-Fibroblast activation protein inhibitor
- Where
- China
- Volunteers
- 22 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Semen Quality
Effect of Combined Aerobic and Resistance Exercise on Semen Quality Among Chinese College Students
The goal of this randomized controlled clinical trial is to investigate the effects of moderate-intensity combined aerobic and resistance exercise on semen quality in Chinese college students.
- Trial name
- NCT06867627
- Testing
- Moderate-intensity combined aerobic and resistance exercise training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Diabetic Retinopathy (DR), Visual Perception
Study on the Recovery of Visual Perceptual Function Dysfunction in Patients With Diabetes
Investigators aim to investigate the effectiveness of visual perceptual learning on visual perceptual function in participants with diabetic retinopathy and to provide novel therapeutic insights for visual functional…
- Trial name
- NCT07095777
- Testing
- visual perceptual learning
- Where
- China
- Volunteers
- 36 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Cerebrovascular Disorders, Intracranial Hemorrhages
Statins for Treatment of Primary Intracerebral Hemorrhage
The STOP ICH trial is a multicenter, prospective, randomized, open-label, blinded end-point (PROBE) study designed to assess the efficacy and safety of atorvastatin in patients with intracerebral hemorrhage (ICH) presenting…
- Conditions
- Cerebrovascular Disorders, Intracranial Hemorrhages, Intracranial Hemorrhage, Intracerebral Haemorrhage
- Trial name
- STOP ICH (NCT07088250)
- Testing
- Atorvastatin Treatment, Best Medical Treatment
- Where
- 22 sites in China
- Volunteers
- 264 people
- Sponsor
- The Second Hospital of Anhui Medical University
After Cardiac Surgery, Diuretic Resistance
Evaluation of the Efficacy of rhBNP in Patients With Diuretic Resistance After Cardiac Surgery
evaluation of the efficacy of recombinant human brain natriuretic peptide in patients with diuretic resistance after cardiac surgery: a prospective single-center single-blind randomized controlled study
- Trial name
- rhBNP (NCT07086287)
- Testing
- rhBNP and standard basic treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Direct Current Stimulation (tDCS), Breast Cancer Survivor
Transcranial Direct Current Stimulation for Cancer-related Cognitive Impairment in Breast Cancer Survivors
This study aims to evaluate the efficacy of transcranial direct current stimulation (tDCS) in improving cancer-related cognitive impairment (CRCI) in breast cancer survivors.
- Conditions
- Transcranial Direct Current Stimulation (tDCS), Breast Cancer Survivor, Cognitive Impairment
- Trial name
- NCT07083518
- Testing
- Anodal transcranial direct current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University