Clinical trials: sponsored by Anhui Medical University
Obsessive-Compulsive Disorder, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Obsessive Compulsive Disease
To investigate the treatment effect of repetitive transcranial magnetic stimulation on Obsessive-compulsive disorder, and the underlying neural mechanism by functional MRI.
- Conditions
- Obsessive-Compulsive Disorder, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Event-Related Potentials
- Trial name
- NCT03393078
- Testing
- transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Anhui Medical University
Schizophrenia, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Schizophrenia Patients With Auditory Hallucinations
To investigate the treatment effect of continuous transcranial magnetic stimulation on schizophrenia patients with auditory hallucinations, and the underlying neural mechanism by functional MRI
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
- Trial name
- NCT02863094
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Opioid Consumption
Application of Rectus Sheath Block based-on Incision in Upper Abdominal Surgery
General anesthesia combined subcostal transversus abdominis plane (TAP)or rectus sheath block (RSB)can significantly reduce the use of opiates in minimally invasive surgery.However, similar reduction was not observed in open…
- Trial name
- NCT04306159
- Testing
- Subcostal TAP, Modified RSB, General anesthesia
- Where
- China
- Volunteers
- 126 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Cholelithiasis, Laparoscopic Cholecystectomy
Rouviere Sulcus Plane and Hepatic Hilum Plane, Which is Better as a Landmark in Laparoscopic Bile Duct Surgerys
RS and the RS plane are important anatomical markers in laparoscopic cholecystectomy. However, there are many variations in the shape and orientation of the RS, and the RS plane is an imaginary plane, which can be misjudged by…
- Trial name
- NCT05002426
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Anhui Medical University
Magnetic Resonance Imaging, Asymptomatic Intracranial Stenosis
Cognitive Decline in Asymptomatic Intracranial Stenosis Patients: A 1-Year Follow-Up Study
To investigate the cognitive decline after standard medical treatment without stenting in Asymptomatic Intracranial Stenosis patients and the underlying neural mechanism by fMRI.
- Conditions
- Magnetic Resonance Imaging, Asymptomatic Intracranial Stenosis, Medical Treatment
- Trial name
- NCT04850001
- Testing
- Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Long-term Heart-specific Mortality in the Presence of Competing Risks Among Patients With Gastric Adenocarcinoma Undergoing Resection and Chemotherapy
Long-term Heart-specific Mortality in the Presence of Competing Risks Among Patients With Non-metastatic Gastric Adenocarcinoma Undergoing Resection and Chemotherapy
In this population-based cohort study, data on patients diagnosed with nmGaC in 2004 through 2016, managed with resection and chemotherapy, followed up until the end of 2016, and surviving ≥1 month were retrieved from the US…
- Trial name
- GaCCoR-01 (NCT04820569)
- Testing
- Resection and chemotherapy
- Volunteers
- 21,257 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Premature Ovarian Failure, Primary Ovarian Insufficiency
Prospective Genetic Study in Patients With Ovarian Insufficiency
genetic screening and etiological analysis was conducted on patients with ovarian insufficiency and decline in ovarian reserve. All patients were enrolled in the IVF-treated and non-IVF-treated groups, followed up for long-term…
- Conditions
- Premature Ovarian Failure, Primary Ovarian Insufficiency, Ovarian Dysgenesis, Diminished Ovarian Reserve
- Trial name
- NCT03474120
- Testing
- IVF treatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Endothelial Dysfunction, Blood Brain Barrier Defect
Endothelial Injury Mechanism in Elderly Patients Undergoing Major Surgery
The incidence of postoperative cognitive injury is high in elderly patients, especially after major surgery. The relevant pathophysiological mechanisms are still unclear, and the possible mechanisms that have been proposed so far…
- Conditions
- Endothelial Dysfunction, Blood Brain Barrier Defect, Postoperative Cognitive Dysfunction
- Trial name
- NCT03639896
- Testing
- Dexmedetomidine, Saline
- Where
- 2 sites in China
- Volunteers
- 464 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Magnetic Stimulation, Magnetic Resonance Imaging
Effect of Theta-Burst Transcranial Magnetic Stimulation (TBS) for Early Alzheimer's Disease
To investigate the treatment effect of theta-burst transcranial magnetic stimulation on Alzheimer patients, and the underlying neural mechanism by MRI.
- Conditions
- Transcranial Magnetic Stimulation, Magnetic Resonance Imaging, Alzheimer Disease
- Trial name
- NCT03612622
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Anhui Medical University
Hepatolithiasis, Laparoscopic Liver Resection
Open Versus Laparoscopic Left Hepatic Sectionectomy
Laparoscopic left sectionectomy has been associated with shorter hospital stay and reduced overall morbidity compared with open left sectionectomy. Strong evidence has not, however, been provided.
- Conditions
- Hepatolithiasis, Laparoscopic Liver Resection, Open Liver Resection, Enhanced Recovery
- Trial name
- NCT03958825
- Testing
- laparoscopic hepatic sectionectomy, open left hepatic sectionectomy
- Where
- China
- Volunteers
- 88 people
- Sponsor
- The Second Hospital of Anhui Medical University
Transcranial Direct Current Stimulation, Major Depressive Disorder
tDCS Intervention on Motivational Anhedonia of Major Depressive Disorder
Study of tDCS intervention on motivational anhedonia of Major Depressive Disorder
- Conditions
- Transcranial Direct Current Stimulation, Major Depressive Disorder, Event-Related Potentials
- Trial name
- NCT04425278
- Testing
- transcranial direct current stimulation with real current
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Stomach Diseases
Diagnosis of Gastric Lesions From Exhaled Breath and Saliva
The investigators study the feasibility of a novel method in oncology based on breath analysis with a nanosensors array for identifying gastric diseases.
- Trial name
- NCT01420588
- Where
- 2 sites in China, Latvia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Gastric Cancer
Capecitabine or Observation for Patients With pT1N+M0 or pT2-3N0M0 Gastric Adenocarcinoma Undergoing R0 Resection
Gastric cancer (GC) is one of the most common and lethal malignancies in Asia. For early (stage T1) GC, it has been found by analyzing surgical specimens that ~5% of cancers have lymph node metastasis.
- Trial name
- CAPOGA (NCT03817268)
- Testing
- Capecitabine monotherapy
- Where
- China
- Volunteers
- 768 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Treatment Resistant Depression, Transcranial Magnetic Stimulation
rTMS Intervention on Motivational Anhedonia of Treatment Resistant Depression and Brian Network Mechanism
Study of individualized accurate targeting rTMS intervention on motivational anhedonia of treatment resistant depression and brain network mechanism
- Conditions
- Treatment Resistant Depression, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Event-Related Potentials
- Trial name
- rTMS (NCT03991572)
- Testing
- repeated transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Circulating Tumor Cell, Volatile Organic Chemicals
Diagnostic Power Comparison Between VOCs and CTCs
Early diagnosis of malignant tumors is pivotal for improving their prognoses. Circulating tumor cells (CTC) in peripheral blood and Volatile organic compounds (VOCs) in exhaled breath are newly developed diagnosis method.
- Conditions
- Circulating Tumor Cell, Volatile Organic Chemicals, Breast Cancer, Gastric Cancer
- Trial name
- NCT03958812
- Testing
- Circulating tumor cells, Volatile organic compounds
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Volatile Organic Compounds, Cancer
Cancer Diagnoses From Exhaled Breath With Na-nose
Early diagnoses of malignant tumors are pivotal for improving their prognoses. The Exhaled Breath is made up of oxygen, carbon dioxide, nitrogen, water, inert gases and volatile organic compounds (VOCs).
- Conditions
- Volatile Organic Compounds, Cancer, Diagnoses Disease
- Trial name
- NCT03967652
- Testing
- Nanomaterial-based sensors
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Cardiac Disease, High Risk Sex
The Effects of Individualized Oxygen Dynamic on Prognosis of Patients With High-risk Cardiac Surgery
Anesthesia-related factors have been linked to poor perioperative outcomes. Our observational study suggested that the cumulative duration of a triple-low state [intraoperative low mean arterial pressure (MAP), low bispectral…
- Trial name
- NCT03103633
- Testing
- mean artery pressure, bispectral index, Brain oxygen saturation
- Where
- China
- Volunteers
- 286 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Parkinson Disease
To investigate the treatment effect of continuous transcranial magnetic stimulation on patients with Parkinson disease, and the underlying neural mechanism by functional MRI
- Conditions
- Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Parkinson Disease
- Trial name
- NCT02969941
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Anhui Medical University
Awake Tracheal Intubation
The Application of Docozine Combined With Sufentanil for Awake Tracheal Intubation
Mortality associated with difficult airway in anesthesia is up to 30%. So, it is urgent to find a safe and effective method for intubation.
- Trial name
- NCT02673723
- Testing
- Docozine, Saline
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Lung Cancer
The Real Word Study of Albumin-binding Taxol for Lung Cancer Treatment
The investigators conduct the real world study to explore the efficacy and safety of Albumin-binding taxol in lung cancer .
- Trial name
- NCT03802409
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University