Clinical trials: sponsored by Asan Medical Center
Gastrointestinal Subepithelial Tumors
EUS-guided Fine Needle Aspiration (EUS-FNA) Versus EUS-guided Fine Needle Biopsy (EUS-FNB) for Diagnosis of Subepithelial Tumors
Background: Preoperative pathologic diagnosis of subepithelial tumor (SET) can improve clinical decision making. Although EUS-guided fine needle aspiration (FNA) is currently considered the standard method for sampling SET, its…
- Trial name
- NCT02943837
- Testing
- Device: 22G FNA needle, Device: 20G FNB needle
- Sponsor
- Asan Medical Center
Crohn's Disease, Ulcerative Colitis
Epidemiology of Inflammatory Bowel Disease in the Songpa-Kangdong District, Seoul, Korea.
The purpose of this study is to evaluate the incidence, prevalence, clinical characteristics and prognosis of Crohn's disease and ulcerative colitis over time in a district of Seoul, Korea.
- Conditions
- Crohn's Disease, Ulcerative Colitis, Epidemiology, Korea
- Trial name
- NCT01731665
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Asan Medical Center
Healthy Volunteer, Alzheimer Disease
Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain
The overall goal of this imaging trial is to evaluate [18F]PI-2620, a tau targeted positron emission computed tomography radioligand, in individuals with tauopathies and healthy volunteers (HV).
- Conditions
- Healthy Volunteer, Alzheimer Disease, Frontotemporal Dementia, Parkinson Disease
- Trial name
- NCT03510572
- Testing
- [18F]PI-2620
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Ulcerative Colitis, Dysplasia
Surveillance in Ulcerative Colitis: Narrow Band Image Versus Chromoendoscopy for High-risk Groups
The risk of colorectal cancer (CRC) is increased in patients having ulcerative colitis (UC). Patients with long-standing extensive colitis, concomitant primary sclerosing cholangitis, or previous history of dysplasia carry an…
- Trial name
- SUNRISE-High (NCT04257084)
- Testing
- chromoendoscopy with target biopsy; NBI with target biopsy
- Volunteers
- 188 people
- Sponsor
- Asan Medical Center
Urachal Cancer
A Multicenter Prospective Phase II Study of Modified FOLFIRINOX for 1st Line Treatment for Advanced Urachus Cancer
This study aims to assess objective response rate of modified FOLFIRINOX in advanced urachaus cancer. Patients with locally advanced, recurrent, or metastatic urachal carcinoma of bladder, urachal will be enrolled this study.
- Trial name
- NCT04611724
- Testing
- FOLFIRINOX
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Asan Medical Center
Interstitial Cystitis, Stem Cell Transplant
Safety of Human Embryonic Stem Cell (hESC)-Derived Mesenchymal Stem Cells in Interstitial Cystitis
This study primarily aimed to evaluate the safety of human embryonic stem cell (hESC)-derived mesenchyma stem cells in interstitial cystitis.
- Conditions
- Interstitial Cystitis, Stem Cell Transplant, Mesenchymal Stem Cell
- Trial name
- NCT04610359
- Testing
- MR-MC-01
- Where
- South Korea
- Volunteers
- 3 people
- Sponsor
- Asan Medical Center
Breast Cancer
Music and Surgery Associated With Relationship and Satisfaction
In this study, the investigators want to check whether it has a direct effect on the participants first, and secondly, whether it affects the relationship between the patient and the doctor or treatment satisfaction, by reducing…
- Trial name
- MARS (NCT04555057)
- Testing
- Music therapy
- Where
- South Korea
- Volunteers
- 304 people
- Sponsor
- Asan Medical Center
Abdominal Pain, Zoster With Other Complications
Frequency of Putative Enteric Zoster Diagnosed Using Saliva Samples in Patients With Abdominal Pain: a Prospective Study
The aim of this study is to identify the frequency of enteric zoster using salivary varicella zoster virus (VZV) DNA PCR in patients who visit the emergency room due to acute abdominal pain.
- Trial name
- NCT03862092
- Testing
- Salivary VZV-DNA PCR
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
CAVD
Randomized, Open-label Trial of Inhibitory Effect of Evogliptin on Progression of CAVD
The purpose of this study is to assess an inhibitory effect of Evogliptin on the progression of mild-to-moderate aortic stenosis in patients with T2DM and calcific aortic stenosis.
- Trial name
- NCT04521452
- Testing
- Evogliptin
- Where
- South Korea
- Volunteers
- 218 people
- Sponsor
- Asan Medical Center
Breast Cancer, Neutropenia
Intermittent G-CSF in Patients With Breast Cancer Receiving Adjuvant Docetaxel, Doxorubicin, and Cyclophosphamide (TAC)
To compare the efficacy and safety of Day 2 (D2) once a cycle pegfilgrastim with Intermittent Every Other Days of 5 Shot (D3-11) filgrastim in early breast cancer patients treated with adjuvant Docetaxel, Doxorubicin, and…
- Conditions
- Breast Cancer, Neutropenia, Febrile Neutropenia
- Trial name
- NCT02685111
- Testing
- Filgrastim, Peg-filgrastim
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Asan Medical Center
Metastatic Breast Cancer
Study of GnRH-A [Leuprorelin(Lorelin Depot] Plus Leterozole +/- Everolimus for Premenopausal Women With Metastatic Breast Cancer
The purpose of this study is to evaluate the efficacy of addition of everolimus to letrozole with LHRH agonist in premenopausal metastatic breast cancer patients who failed to tamoxifen treatment.
- Trial name
- LEO (NCT02344550)
- Testing
- Everolimus(afinitor), Letrozole, Leuprolide(Lorelin Depot)
- Where
- South Korea
- Volunteers
- 137 people
- Sponsor
- Asan Medical Center
Metastatic Breast Cancer
Eribulin Plus Gemcitabine (EG) vs Paclitaxel Plus Gemcitabine (PG) in HER2-Negative Metastatic Breast Cancer
Metastatic breast cancer (MBC) is an incurable disease and is needed to improve effective chemotherapy. Paclitaxel plus Gemcitabine (PG) combination chemotherapy is one of the preferred chemotherapeutic regimens for patients with…
- Trial name
- EG_PG (NCT02263495)
- Testing
- Paclitaxel, Eribulin, Gemcitabine
- Where
- 2 sites in South Korea
- Volunteers
- 118 people
- Sponsor
- Asan Medical Center
Gastrointestinal Stromal Tumors (GISTs)
L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors
we aim to evaluate the efficacy of L-carnitine for the treatment of muscle cramps after imatinib in patients with GIST and apply in the future.
- Trial name
- NCT03426722
- Testing
- L-carnitine
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Asan Medical Center
Dyspepsia
Change of Gut Microbiome and Symptom After H.Pylori Eradication Therapy in Patients With Functional Dyspepsia
The aims of the investigators' study are to investigate the effect of H.pylori eradication on the human gut microbiome and symptoms of functional dyspepsia.
- Trial name
- NCT04449185
- Testing
- Tegoprazan 50mg bid + amoxicillin 1000mg bid + clarithromycin 500mg bid for 10 days
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Caudal Epidural Block
Estimation of Injection Volume for Caudal Epidural Block Using Dynamic US Imaging in Children
Caudal epidural block is the most commonly used technique for analgesia in pediatric patients. Although there are clinically used doses of local anesthetics for caudal epidural block, we do not know exactly how much levels are…
- Trial name
- NCT04039295
- Testing
- ultrasound guided caudal epidural block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Laryngeal Masks, Urinary Bladder Neoplasms
Effect of Head Elevation on LMA Insertion
The purpose of this study is to compare the first attempt success rate of laryngeal mask airway insertion according to the degree of head elevation.
- Trial name
- NCT04229862
- Testing
- Laryngeal mask airway insertion
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
COVID-19
Comparison of Lopinavir/Ritonavir or Hydroxychloroquine in Patients With Mild Coronavirus Disease (COVID-19)
In vitro studies revealed that lopinavir/ritonavir and hydroxychloroquine have antiviral activity against Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT04307693
- Testing
- Lopinavir/ritonavir, Hydroxychloroquine sulfate
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Asan Medical Center
Free Tissue Flaps
Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap
Comparing the changes of arterial anastomotic blood flow between general anesthesia alone and general anesthesia with epidural anesthesia in patients who undergoing free flap transposition using Duplex ultrasound.
- Trial name
- NCT03330808
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Inhospital Cardiac Arrest
Neurological Outcomes After In-Hospital Cardiac Arrest
Little is known about the long-term neurological outcomes after in-hospital cardiac arrest (IHCA). It is also not known whether withdrawal of life-sustaining measures will influence rates of survivors with poor neurological…
- Trial name
- NO-IHCA (NCT03006484)
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 322 people
- Sponsor
- Asan Medical Center
Head and Neck Neoplasm
Preoxygenation With a High-flow Nasal Cannula or a Simple Mask Before General Anesthesia in Head and Neck Surgery
Objectives: To assess arterial oxygen partial pressure (PaO2) at defined time points during the preoxygenation and to compare between high flow heated humidified nasal oxygen versus standard preoxygenation with oxygen insufflation…
- Trial name
- NCT03896906
- Testing
- High-flow nasal cannula, simple mask
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center