Clinical trials: sponsored by Asan Medical Center
Prostate Cancer
Effect of Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy
The purpose of this study was to evaluate the difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia in patients…
- Trial name
- NCT03271502
- Testing
- Total intravenous anesthesia, Inhalation anesthesia
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Asan Medical Center
Bladder Cancer, Ureter Cancer
Four Cycles Versus Six Cycles of Cisplatin-based Chemotherapy in Metastatic Urothelial Carcinoma
The objective is to show non-inferiority of overall survival between four cycles and six cycles of first-line cisplatin based chemotherapy to determine the optimal duration of chemotherapy in patients with advanced urothelial…
- Conditions
- Bladder Cancer, Ureter Cancer, Urethral Cancer, Transitional Cell Carcinoma
- Trial name
- FOCUS (NCT03296306)
- Testing
- Treatment duration of cisplatin based chemotherapy
- Where
- 19 sites in South Korea
- Volunteers
- 330 people
- Sponsor
- Asan Medical Center
Hepatocellular Carcinoma
Sorafenib vs.TransArterial Chemoembolization Plus RadioTherapy in Hepatocellular Carcinoma With Macrovascular Invasion
To evaluate and compare the efficacy and safety of sorafenib versus trans-arterial chemoembolization plus external beam radiation therapy in patients with hepatocellular carcinoma invading major intrahepatic vessels
- Trial name
- START (NCT01901692)
- Testing
- TACE+External beam RT, Sorafenib
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Asan Medical Center
Pancreatic Neoplasm, Pancreatic Periampullary Cancer
The Effect of Application of TachoSil® in Pancreatoduodenectomy
Fibrinogen/thrombin-coated collagen patch (TachoSil®) is known to have the effect of strengthening tissue anastomosis and promoting suturing to prevent leakage.
- Conditions
- Pancreatic Neoplasm, Pancreatic Periampullary Cancer, Pancreatic Bordeline Tumor
- Trial name
- NCT03269955
- Testing
- Fibrinogen/thrombin-coated collagen patch
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Asan Medical Center
Breast Cancer
Neoadjuvant Combined Endocrine and HER2 Target Therapy in Postmenopausal Women With ER and Her2 Positive Breast Cancer
Cross-talk between epidermal growth factors and the ER occurs at multiple levels and seems to play a crucial role in breast cancer progression and endocrine resistance.Combined HER1/HER2-targeted therapy with aromatase inhibitors…
- Trial name
- Neo-All-In (NCT01275859)
- Testing
- Letrozole, Lapatinib
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Asan Medical Center
Breast Cancer
Neoadjuvant Chemotherapy of 6 Cycles vs 8 Cycles in Node Positve Breast Cancer
Various regimens and schedule as neoadjuvant chemotherapy regimens were investigated and sequential treatment of anthracyclines followed by taxanes, which has shown superior pathologic complete respone (pCR) rate (NSABP-B27…
- Trial name
- Neo-shorter (NCT02001506)
- Testing
- FEC3-D3
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Asan Medical Center
Esophageal Squamous Cell Carcinoma
Role of Esophagectomy in Complete Responders to CCRT
To investigate the role of esophagectomy in complete responders to preoperative chemoradiotherapy for squamous cell carcinoma of esophagus, patients will be randomized to either observation or esophagectomy after concurrent…
- Trial name
- ESOPRESSO (NCT01740375)
- Testing
- esophagectomy
- Where
- South Korea
- Volunteers
- 486 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Effect of Mannitol on Optic Nerve Sheath Diameter in Patients Undergoing Robotic Prostatectomy
We aim to evaluate the change in optic nerve sheath diameters as a surrogate of intracranial pressure before and after mannitol administration in patients who undergo robot assisted laparoscopic radical prostatectomy with…
- Trial name
- NCT03214055
- Testing
- Mannitol
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Asan Medical Center
Gastric Cancer
Dovitinib Plus Docetaxel in Gastric Cancer
Docetaxel is currently one of standard second-line therapy in patients with gastric cancer. As angiogenesis and FGFR pathway has been suggested to be associated with gastric cancer, dovitinib, dual VEGFR and FGFR inhibitor, may…
- Trial name
- NCT01921673
- Testing
- Dovitinib and docetaxel
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Asan Medical Center
Type 2 Diabetes Mellitus
Correlation Between Change of HbA1c, Urinary Glucose Excretion and Other Factors in Patients Treated With Ipragliflozin
The purpose of this study is to examine the correlation between change of HbA1c, urinary glucose excretion and other factors when ipragliflozin is added to preexisting therapy in subjects with type 2 diabetes.
- Trial name
- NCT02791035
- Testing
- Oral administration of Ipragliflozin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Pulmonary Emphysema
The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients
To assess efficacy of bronchoscopic lung volume reduction in Korean emphysema patients
- Trial name
- NCT01869205
- Testing
- Endobronchial valve
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Asan Medical Center
Bladder Cancer, Ureter Cancer
Pemetrexed Maintenance in Patients With Urothelial Carcinoma Who Completed First Line Platinum-based Chemotherapy
This study aims to verify superiority of pemetrexed maintenance to observation for patient without disease progression after 1 st line cisplatin-based chemotherapy.
- Conditions
- Bladder Cancer, Ureter Cancer, Transitional Cell Carcinoma
- Trial name
- PREMIER (NCT03193788)
- Testing
- pemetrexed, Folic Acid, Vitamin B12 Injection
- Where
- 21 sites in South Korea
- Volunteers
- 74 people
- Sponsor
- Asan Medical Center
Periampullary Tumor
The Effect of ERAS on Pancreaticoduodenectomy
Enhanced Recovery After Surgery (ERAS) is not the program that aim to reduce postoperative hospital stay, but the multimodal strategies that aim to attenuate the loss of, and improve the restoration of,functional capacity after…
- Trial name
- ERAS (NCT02372331)
- Testing
- ERAS perioperative management
- Where
- South Korea
- Volunteers
- 276 people
- Sponsor
- Asan Medical Center
Advanced or Recurrent Endometrial Cancer
Efficacy Study of Chemotherapy to Treat Advanced or Recurrent Endometrial Cancer
The purpose of this study is to treat advanced or recurrent endometrial cancer, paclitaxel-containing regimen is the preferred chemotherapeutic regimen which is selected by most physicians.
- Trial name
- NCT01461759
- Testing
- Doctaxel, Cisplatin
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Asan Medical Center
Cervical Intraepithelial Neoplasia, Cervical Cancer
The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP)
This study is aimed at identifying the efficacy of Tachosil® for prevention of hemorrhage in patients with cervical intraepithelial neoplasia or cervical cancer after undergoing a loop electrosurgical excisional procedure (LEEP).
- Trial name
- TACO (NCT02629510)
- Testing
- Tachosil
- Where
- South Korea
- Volunteers
- 268 people
- Sponsor
- Asan Medical Center
Cervical Cancer
Significance of Fluorescence Colposcopy With Autofluorescence Imaging for Cervical Cancer
Clinical Trial to access Significance of fluorescence colposcopy with autofluorescence imaging for the screening of cervical cancer
- Trial name
- NCT01854983
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Gynecologic Cancer, Cervical Cancer
Efficacy Study of FloSeal for Prevention of Lymphocele After Lymphadenectomy for Gynecologic Cancer
To compare the incidence of lymphocele and lymphatic ascites between patient who use versus who do not use FloSeal during lymph node dissection
- Conditions
- Gynecologic Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT01679483
- Testing
- FloSeal application
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Cervical Cancer
Radical Hysterectomy Followed by Tailored Adjuvant Therapy Versus Primary Chemoradiation Therapy in Bulky Early-stage Cervical Cancer (KGOG 1029)
To compare 5-year overall survival between patients who undergo radical hysterectomy followed by tailored adjuvant therapy and patients who receive primary chemoradiation therapy in FIGO stage IB2 and IIA2 cervical cancer
- Trial name
- NCT01680523
- Testing
- Radical hysterectomy, Tailored adjuvant therapy, Primary chemoradiation therapy
- Where
- South Korea
- Volunteers
- 409 people
- Sponsor
- Asan Medical Center
Epithelial Ovarian Cancer
Study on Neutropenia Induced by Adjuvant Paclitaxel/Carboplatin Chemotherapy in Patients With Epithelial Ovarian Cancer
To develop a robust prediction model to predict the occurrence of grade 3-4 neutropenia induced by adjuvant paclitaxel/carboplatin chemotherapy in patients with epithelial ovarian cancer and to validate this model.
- Trial name
- NCT01680575
- Where
- South Korea
- Volunteers
- 750 people
- Sponsor
- Asan Medical Center
Cervical Cancer
Efficacy and Safety Study of Concurrent Chemoradiation Therapy to Treat Locally Advanced Cervical Cancer
Concurrent chemoradiation therapy with weekly cisplatin is the current standard treatment for patients with locally advanced cervical cancer. However, weekly cisplatin is related to renal toxicity and not convenient regimen.
- Trial name
- NCT01461772
- Testing
- Radiation therapy, Carboplatin, Cisplatin
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Asan Medical Center